Ragged-red fibers, a characteristic microscopic abnormality observed in muscle biopsy, are commonly present with this form.[5] In some individuals, encephalomyopathy does not begin until childhood or adulthood. [rarediseases.info.nih.gov]

• Heart Disease

  Some affected individuals have a form of heart disease called cardiomyopathy, which can lead to heart failure. Most people with mitochondrial complex III deficiency have a buildup of a chemical called lactic acid in the body (lactic acidosis). [ghr.nlm.nih.gov]

• Global Developmental Delay

  developmental delay 0001263 Hallucinations Hallucination Sensory hallucination [ more ] 0000738 Hyperreflexia Increased reflexes 0001347 Hypertrophic cardiomyopathy Enlarged and thickened heart muscle 0001639 Hypoglycemia Low blood sugar 0001943 Increased [rarediseases.info.nih.gov]

• Hyperreflexia

  Weight faltering [ more ] 0001508 Feeding difficulties in infancy 0008872 Generalized hypotonia Decreased muscle tone Low muscle tone [ more ] 0001290 Global developmental delay 0001263 Hallucinations Hallucination Sensory hallucination [ more ] 0000738 Hyperreflexia [rarediseases.info.nih.gov]

You may also want to contact a university or tertiary medical center in your area, because these centers tend to see more complex cases and have the latest technology and treatments. [rarediseases.info.nih.gov]

Endothelial dysfunction and coronary artery disease: assessment, prognosis and treatment. Coron Artery Dis, 25(8), 713-724. [ Links ] 30. Hadi, H., Carr, C. and Suwaidi, J. (2005). [scielo.sa.cr]

Antimycin A locks the b hemes in the reduced state by preventing their re-oxidation at the Qi site, which, in turn, causes the steady-state concentrations of the Qo semiquinone to rise, the latter species reacting with oxygen to form superoxide. [en.wikipedia.org]