We used the vigilance promoting drug modafinil to prevent such attacks in a case presented with endozepine stupor. [ncbi.nlm.nih.gov]

• Anhedonia

  CONCLUSIONS: The present study showed that modafinil affects reward processing in the NAc in healthy subjects through enhancing more positive anticipation, and it may provide a basis for the use of this drug for treating anhedonia observed in psychiatric [ncbi.nlm.nih.gov]

  His dysphoric mood and lethargy improved and his level of anhedonia and amotivation decreased. In literature, only one case study has been reported on modafinil dependence at higher doses. [doi.org]

  There are, however, reported withdrawal symptoms like lethargy, anhedonia, insomnia, and anxiety. [ukmeds.co.uk]

• Dysphoric Mood

  His dysphoric mood and lethargy improved and his level of anhedonia and amotivation decreased. In literature, only one case study has been reported on modafinil dependence at higher doses. [doi.org]

• Auditory Hallucination

  The course of illness was continuous characterized by withdrawn behavior, preoccupation, fear, auditory hallucinations, referential delusions and decline in social and occupational functioning. [doi.org]

• Sexual Dysfunction

  Premature ejaculation (PE) is considered to be the most common form of male sexual dysfunction. [ncbi.nlm.nih.gov]

• Hyperactivity

  Drugs under investigation for attention-deficit hyperactivity disorder. Curr Opin Investig Drugs 2002 ; 3: 1207 – 11. Google Scholar | Medline 4. [dx.doi.org]

  The drug resolved both the inattention/hyperactivity symptoms as well as the amphetamine abuse. Modafinil may be a suitable candidate treatment for adults with ADHD and stimulant abuse. [ncbi.nlm.nih.gov]

• Agitation

  We describe 2 cases in which administration of modafinil exacerbated agitation and hallucinations in DLB, and we also review data that may explain the mechanisms underlying this effect. [ncbi.nlm.nih.gov]

  Mental illness: Modafinil may reactivate certain mental disorders or cause confusion and agitation. [chealth.canoe.com]

  […] urinating uncontrolled movements of the face, mouth, or tongue unusual bleeding or bruising unusual tiredness or weakness Get emergency help immediately if any of the following symptoms of overdose occur while taking modafinil: Symptoms of Overdose Agitation [drugs.com]

  Side effects which have been reported by patients include: Headache Diarrhoea Nervousness or anxiety Agitation confusion Tremors Insomnia Hypertension (high blood pressure) Palpitations Tachycardia Angioedema Psychosis Depression or other behavioural [unitedpharmacies-uk.md]

• Akinesia

  The profound akinesia induced by reserpine (4 mg/kg s.c.; 5 h before testing) was reversed by (+)amphetamine 2 mg/kg but not by modafinil 40 mg/kg. [ncbi.nlm.nih.gov]

• Dyslipidemia

  As co-morbidities the patient demonstrated overweight (IMC=29), systemic arterial hypertension and dyslipidemia. [ncbi.nlm.nih.gov]

No adverse events of treatment with modafinil and intranasal mometasone furoate were reported. Cost of treatment and beneficial effect after discontinuation were both significantly greater for the IMFG compared with the MG. [ncbi.nlm.nih.gov]

We did not include studies comparing different types of cancer‐modifying treatment and the effect on prognosis and quality of life. We also excluded those studies which did not focus on pharmacological treatment. [doi.org]

Deficits in the dopamine receptor system are involved in the etiology of apathy; modafinil's increased dopaminergic transmission is thought to help alleviate apathy. [ncbi.nlm.nih.gov]

Thus, despite numerous investigations, the etiology of SLE-associated cognitive dysfunction remains unclear. There is no known means for preventing cognitive dysfunction in SLE. [clinicaltrials.gov]

Michael Thorpy, Current concepts in the etiology, diagnosis and treatment of narcolepsy, Sleep Medicine, 2, 1, (5), (2001). Michael H. Silber, Sleep disorders, Neurologic Clinics, 19, 1, (173), (2001). [doi.org]

Patients completed the Center for Epidemiological Studies-Depression Scale (CES-D) and Profile of Mood States depression-dejection subscale at baseline and posttest. [ncbi.nlm.nih.gov]

Epidemiology, evaluation of the sleepy patient, diagnostic investigations including neuroimaging, subjective and objective testing, cognitive effects of sleepiness, motor vehicle driving issues, medico-legal aspects of sleepiness, and therapy are also [books.google.it]

Tiredness, sedation assessed with scales such as the Chalder Fatigue Scale (CFS) or Center for Epidemiologic Studies Depression (CESD) scale. [doi.org]

In accord with this mission, this peer-reviewed, rapid-publication, international journal publishes both basic and clinical contributions from all disciplines and research areas relevant to the pathophysiology and treatment of major psychiatric disorders [elsevier.com]

Circadian rhythm sleep disorders: pathophysiology and treatment. J Clin Neurophysiol 1996 ;13: 17 - 31 20. Zisapel N. Circadian rhythm sleep disorders: pathophysiology and potential approaches to management. CNS Drugs 2001 ;15: 311 - 328 21. [nejm.org]

This effect may also interact with underlying pathophysiology in this system, manifest in either neurochemical disturbances and/or altered responses to cognitive demands 35, 36, 37, 38, 39. [nature.com]

We used the vigilance promoting drug modafinil to prevent such attacks in a case presented with endozepine stupor. [ncbi.nlm.nih.gov]

Modafinil dose-dependently prevented the decline in motor activity normally produced by MPTP treatment. [springerlink.com]

We test modafinil, a novel wake-promoting agent, as monotherapy for atypical depression in a double-blind, placebo-controlled, relapse prevention trial after open-label treatment. [oadoi.org]