A total of 190 patients were diagnosed to have MMA in our institute over the last 27 years and this is the first case of familial MMA. [ncbi.nlm.nih.gov]

In conclusion, a large cohort of patients with monomelic amyotrophy seen over 35 years (1976–2010) is described. [doi.org]

Over 20 NEW test entries present the latest tests and procedures, with a strong focus on affordable, clinically relevant genetic tests. [books.google.com]

On neutral studies, cervical lordosis was scored as either normal or abnormal and LOA was determined as either present or absent at each cervical level and the first thoracic level by using the methods described by Chen et al. 8 Cervical lordosis was [doi.org]

Neutral position MRI showed loss of cervical lordosis in 10/11 (91%), localized lower cervical cord atrophy in 9/11 (82%), asymmetric cord flattening in 11/11 (100%) and intramedullary hyperintensity in 2/11 (18%); flexion study showed loss of dural attachment [ncbi.nlm.nih.gov]

Studies consistently note a loss of normal neck curvature (the cervical lordosis) and compression of the cervical chord by the dural sac in forward flexion. [en.wikipedia.org]

Physiotherapy is helpful in preventing complications resulting from immobility such as joint stiffness and muscle wasting. [jmedicalcasereports.biomedcentral.com]

He denied history of trauma, shoulder pain, or sensory symptoms, and he was not on any medications prior to development of symptoms. [jmedicalcasereports.biomedcentral.com]

Furthermore, this atrophy is rarely associated with osteophyte compression of the anterior spinal cord or with disc bulges. [cns.org]

Other symptoms are: • Difficulty in gripping • Hand tremors • Weak and atrophied hand, forearm muscles • Weakness of a single limb • Fine motor control issues Diagnoses The diagnostic criterion for Monomelic Amyotrophy isn’t different. [startstemcells.com]

The signs and symptoms of Hirayama's disease can include: No pain Weak grip Clawed hand Hand tremors Weak hand muscles Wasted hand muscles Wasting of a single limb Weak lower arm muscles Weakness of a single limb Wasted lower arm muscles Fine motor control [disabled-world.com]

Arch Neurol 54 : 46 – 50 1997 Search Google Scholar Export Citation 24 Sakai K Ono K Okamoto Y Murakami H Yamada M : Cervical flexion myelopathy in a patient showing apparent long tract signs: a severe form of Hirayama disease. [doi.org]

Necropsy in 1 patient identified anterior horn cell shrinkage, necrosis, and gliosis in appropriate spinal cord segments. Symptoms and signs often progress for several years before spontaneously arresting. [ncbi.nlm.nih.gov]

An autopsy study on a patient with MA noticed anterior horn cell shrinkage and necrosis, various degrees of degeneration of small and large nerve cells, mild gliosis, and some circulatory insufficiency in the territory of the spinal cord. [jmedicalcasereports.biomedcentral.com]