March 1, 2008 Arch Ophthalmol. 2008;126(3):431-432. doi:10.1001/archopht.126.3.431 We recently encountered a case of developmental glaucoma with systemic malformations including polydactyly, retained testis, hydronephrosis, and epilepsy. [jamanetwork.com]

The surgical procedures performed will depend upon the severity of the anatomical abnormalities and their associated symptoms. [rarediseases.org]

Restriction of salt in the diet, drugs that help to eliminate excessive fluid from the body (diuretics), and/or bed rest may also be effective therapies for congestive heart failure. [rarediseases.org]

Symptoms associated with cardiac failure may include an abnormally rapid rate of breathing (tachypnea), wheezing, an unusually fast heartbeat (tachycardia), abnormal enlargement of the liver (hepatomegaly), and/or failure to thrive. [rarediseases.org]

Maternal serum alpha‐fetoprotein (AFP) screening at 19 weeks' gestation demonstrated a high level of 2·5 multiples of the median (MOM) and ultrasonography at 27 weeks' gestation showed severe intrauterine growth retardation, cardiomegaly, an occipital [obgyn.onlinelibrary.wiley.com]

X-ray studies may reveal abnormal enlargement of the heart (cardiomegaly) or malformation of other heart structures. An EKG, which records the heart’s electrical impulses, may reveal abnormal electrical patterns. [rarediseases.org]

At 2 months of age, he was admitted to another hospital and developmental glaucoma was suspected based on findings of enlarged corneal diameter, ocular hypertension, and bilateral abnormal optic discs. [jamanetwork.com]

Symptoms associated with cardiac failure may include an abnormally rapid rate of breathing (tachypnea), wheezing, an unusually fast heartbeat (tachycardia), abnormal enlargement of the liver (hepatomegaly), and/or failure to thrive. [rarediseases.org]

The proband postnatally displayed additional abnormalities such as microphthalmia, hypertelorism, large low‐set ears, and micrognathia. [obgyn.onlinelibrary.wiley.com]

ears; and/or a short neck with abnormal skin folds (webbing). [rarediseases.org]

There were Haab striae but no embryotoxon or corneal edema in both corneas. The vertical cup to disc ratio was 0.95. The pupil, lens, retina, and vitreous appeared normal bilaterally. Trabeculotomy was performed in both eyes on the same day. [jamanetwork.com]

Symptoms associated with cardiac failure may include an abnormally rapid rate of breathing (tachypnea), wheezing, an unusually fast heartbeat (tachycardia), abnormal enlargement of the liver (hepatomegaly), and/or failure to thrive. [rarediseases.org]