Presentation
We propose that eosinophilic cystitis in children who present with peripheral eosinophilia will often require long-term treatment. [ncbi.nlm.nih.gov]
We also present the positions of the FDA, manufacturer, and national organizations of allergists and immunologists on the possible role of montelukast in suicidality. [oadoi.org]
Entire Body System
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Turkish
Impurities (sulfoxide, cis-isomer, Michael adducts-I&II, methylketone, methylstyrene) were quantified using RP-HPLC analysis on commercial products available in Turkish market. [ncbi.nlm.nih.gov]
Musculoskeletal
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Osteopenia
However, side effects due to long term use of steroids such as growth stunting and bone osteopenia should also be considered before recommending. Trial registered at CTRI no. REF/2012/09/004035. [ncbi.nlm.nih.gov]
Face, Head & Neck
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Facial Numbness
Upon arrival at the ED, the patient had severe jaw tightness, facial numbness, uncontrollable cheek lifting, swollen eyes, and a swollen protruding tongue and was unable to catch her breath. [ncbi.nlm.nih.gov]
Urogenital
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Urinary Urgency
When montelukast 10 mg was initiated for allergic rhinitis symptoms, a substantial improvement in urinary urgency and pain during therapy was noted. This improvement subsequently disappeared when montelukast was stopped. [ncbi.nlm.nih.gov]
Neurologic
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Neurologic Manifestation
Abstract Churg-Strauss syndrome (CSS) is a disseminated small vessel vasculitis characterized by late-onset asthma, upper airways disease, eosinophilia and late neurological manifestations such as peripheral neuropathy. [ncbi.nlm.nih.gov]
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Sensory Deficit of the Lower Extremity
The patient was admitted in our hospital with fever, malaise, sensory deficits in the lower extremities, diffuse musculoskeletal and thoracic pain. [ncbi.nlm.nih.gov]
Treatment
In general, treatment for IC includes systemic medical therapy, local bladder treatment, surgical and neurosurgical procedures, and intravesical drug installation. [ncbi.nlm.nih.gov]
Prognosis
Some of these cases are characterized by severe prognosis (i.e. neurological deficit and fatal hepatotoxicity). Key Message: The use of montelukast can be burdened by several ADRs, of which physicians should be aware in their clinical practice. [ncbi.nlm.nih.gov]
This rare vasculitis presents a broad range of clinical manifestations, sometimes characterized by a severe prognosis and permanent sequelae. CSS affects especially adult patients of both genders. [karger.com]
Prognosis for spontaneous resolution of OSA in children. Chest 2015 ;148: 1204 – 1213. 17. Trosman SJ, Eleff DJ, Krishna J, Anne S. [atsjournals.org]
We have also taken into account that the study was performed in patients with a late diagnosis of BOS (mean time of diagnosis around 5y after LTx), and it is known that late-onset BOS patients have a better prognosis than rapid decliners and early-onset [journals.plos.org]
Etiology
Briggs, Freeman, & Yaffe – Montelukast is not teratogenic in animals, and few adverse outcomes in humans do not demonstrate a pattern that suggests a common etiology. [americanpregnancy.org]
In recent years, increasing evidence has suggested that regulatory T-cells are involved in various skin diseases and play a pivotal role in the etiology of AD. [peertechz.com]
Epidemiology
More accurate epidemiological studies, in order to discover risk factors favouring montelukast-associated ADRs, are demanded. 2014 S. Karger AG, Basel. [ncbi.nlm.nih.gov]
Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA; 5 Department of Clinical Pharmacy, School of Pharmacy, University of Colorado, Aurora, CO, USA; 6 Division of Epidemiology [dx.doi.org]
Division of Epidemiology and Biostatistics, School of Public Health University of Illinois at Chicago Chicago USA 4. Center for Management of Complex Chronic Care Hines VA Hospital Hines USA 5. [oadoi.org]
Pathophysiology
Eosinophilic peritonitis is a recognised complication of peritoneal dialysis and has an incompletely understood pathophysiology. [ncbi.nlm.nih.gov]
Drugs used in the treatment of asthma must be targeted at reversing three principle pathophysiologic features: bronchoconstriction, mucus plugging/hypersecretion and inflammation. [oadoi.org]
Prevention
(via oxoacid ) leukotriene antagonist A drug designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. [ebi.ac.uk]
In conclusion, montelukast is an effective option for prevention of OHSS, as well as cabergoline. Montelukast may be a new treatment option to prevent and control the OHSS. [ncbi.nlm.nih.gov]