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Moraxella Catarrhalis

Branhamella Catarrhalis


Presentation

  • In addition, mortality is substantial among bacteremic patients with respiratory conditions or other chronic debilities, especially when respiratory copathogens are present.[ncbi.nlm.nih.gov]
  • Pathology revealed a synchronous presentation of an osteoma and mucopyocele with intracranial abscess caused by M. catarrhalis. Synchronous presentation of a frontal osteoma with mucopyocele is a rare event.[ncbi.nlm.nih.gov]
  • This report presents a case history of a 22-year-old man with compromised immune status and severe pneumonia caused by M. catarrhalis.[ncbi.nlm.nih.gov]
  • The present case report describes clinical and initial chest roentgenographic presentations of Moraxella catarrhalis pneumonia in AIDS patient.[ncbi.nlm.nih.gov]
  • A brief review of the literature describing the disease entities with which M. catarrhalis has been associated is presented.[ncbi.nlm.nih.gov]
Fever of Unknown Origin
  • A case of bacterial endocarditis caused by Moraxella catarrhalis in an apparently immunocompetent Greek male is presented, which was diagnosed after a 2-month history of low-grade fever of unknown origin.[ncbi.nlm.nih.gov]
Altered Mental Status
  • A 63-year-old man with an aortic bioprosthetic valve was brought to the emergency room with altered mental status.[ncbi.nlm.nih.gov]

Treatment

  • Bacteremia due to this organism therefore requires prompt treatment, as serious organ complications, including endocarditis, can occur.[ncbi.nlm.nih.gov]
  • Finally, we demonstrate that endovascular embolization may be part of the treatment paradigm of frontal osteomas in selected cases.[ncbi.nlm.nih.gov]
  • The infection responded to treatment with broad-spectrum antibiotics, and 2 months after presentation the visual acuity had returned to 20/50.[ncbi.nlm.nih.gov]
  • If she has clinically defined treatment failure after 3 days of treatment, administer high-dose amoxicillin-clavulanate, cefuroxime axetil, or I.M. ceftriaxone.[journals.lww.com]

Prognosis

  • The prognosis is good for febrile neutropenic patients with underlying leukemia or lymphoma when the neutropenia resolves.[ncbi.nlm.nih.gov]
  • The overall prognosis of M. catarrhalis bacteraemia was good, the exception being when it caused endocarditis (5 cases), where mortality rates as high as 80% have been reported.[ncbi.nlm.nih.gov]
  • Prognosis among the immunocompromised, those with underlying lung disease, those in hospital, the elderly and the very young is variable but tends to be worse.[patient.info]
  • What Is the Prognosis for Moraxella Catarrhalis? Despite aggressive moraxella catarrhalis treatment, some people may experience complications.[enkiverywell.com]
  • Prognosis The prognosis of M catarrhalis infection is poor in hospitalized patients with underlying conditions, especially the following: Patients hospitalized for prolonged periods Patients in pulmonary units or pediatric intensive care units Patients[emedicine.medscape.com]

Etiology

  • Multibacterial etiology was seen in 34 (38%) samples, and M. catarrhalis was detected in most (85%) of those cases. Fifteen signals for M. catarrhalis were strong, suggesting a highly probable etiological role of the pathogen.[ncbi.nlm.nih.gov]
  • Moraxella catarrhalis (M. catarrhalis) is the third most common bacteria found in acute otitis media, and in recent years its importance as an etiological factor of acute otitis media has markedly increased in certain geographic areas.[ncbi.nlm.nih.gov]
  • To our knowledge, Moraxella species have been reported as the etiologic agent in three cases[jamanetwork.com]

Epidemiology

  • Author information 1 Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. 2 Milken Institute School of Public Health, Department of Epidemiology and Biostatistics[ncbi.nlm.nih.gov]
  • ISSN: 0950-2688 EISSN: 1469-4409 URL: /core/journals/epidemiology-and-infection[cambridge.org]
  • The clinical and epidemiological features of an outbreak of nosocomial Moraxella catarrhalis infection in a respiratory unit are described.[ncbi.nlm.nih.gov]
  • Molecular and typing studies have shown that the M. catarrhalis species is genetically heterogeneous and these methods have aided epidemiological investigation.[ncbi.nlm.nih.gov]
  • […] last authored: last reviewed: Introduction The Case of... return to top Epidemiology There is nearly 50% carrier rate. return to top Classification and Characteristics M. catarrhalis is a small gram negative cocco-baccili. return to top Transmission and[sharinginhealth.ca]
Sex distribution
Age distribution

Pathophysiology

  • The case presented suggests the pathophysiology of this rare condition. One previous case of septic arthritis caused by M. catarrhalis without documented bacteremia has been reported.[ncbi.nlm.nih.gov]
  • The case presented suggests the pathophysiology ofthis rare condition. One previous case of septic arthritis caused by M. catarrhalis without documented bacteremia has been reported.[academic.oup.com]
  • Pathophysiology and Etiology Studies have shown that M catarrhalis colonizes the upper respiratory tract in 28-100% of humans in the first year of life. In adults, the colonization rate is 1-10.4%.[emedicine.medscape.com]
  • The outer membrane protein OlpA has been shown to play a role in the pathophysiology of M. catarrhalis. Bernard et al. demonstrated that this outer membrane protein binds Factor H, an important complement regulator.[antimicrobe.org]

Prevention

  • Given the global impact of otitis media and COPD, an effective vaccine to prevent M. catarrhalis infection would have a huge impact on the quality of life in both patient populations by preventing disease, thus reducing morbidity and health care costs[ncbi.nlm.nih.gov]
  • A vaccine to prevent M. catarrhalis infections would have an enormous impact globally in preventing morbidity caused by M. catarrhalis in these populations.[ncbi.nlm.nih.gov]
  • Collaboration, Nonthaburi. 4 Division of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia. 5 Medical Research Council Unit, Basse, The Gambia. 6 Department of Paediatrics, University of[ncbi.nlm.nih.gov]
  • […] catarrhalis OMPCD, in addition to its functions related to bacterial growth and adherence to human epithelial cells, plays a very important role in bacterial physiology and pathogenesis, including aspects such as stabilizing bacterial cell morphology and preventing[ncbi.nlm.nih.gov]
  • As virtually all M. catarrhalis isolates are β-lactamase positive, the goal of this study was to investigate whether M. catarrhalis OMVs carry β-lactamase and to analyze if OMV consequently can prevent amoxicillin-induced killing.[ncbi.nlm.nih.gov]

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