Presentation
In addition, mortality is substantial among bacteremic patients with respiratory conditions or other chronic debilities, especially when respiratory copathogens are present. [ncbi.nlm.nih.gov]
Entire Body System
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Fever of Unknown Origin
A case of bacterial endocarditis caused by Moraxella catarrhalis in an apparently immunocompetent Greek male is presented, which was diagnosed after a 2-month history of low-grade fever of unknown origin. [ncbi.nlm.nih.gov]
Gastrointestinal
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Regurgitation
During antibiotic treatment, fever and infectious parameters disappeared, but severe aortic regurgitation developed. Aortic valve replacement was performed, during which extensive destruction of the aortic valve was noted. [ncbi.nlm.nih.gov]
Workup
Diagnostic workup as per BTS guidelines helped in finding the etiologies which lead to change in the patient management. [cureus.com]
Treatment
Bacteremia due to this organism therefore requires prompt treatment, as serious organ complications, including endocarditis, can occur. [ncbi.nlm.nih.gov]
Treatments for Moraxella Catarrhalis: In this section, we will know about some of the treatment for Moraxella Catarrhalis. [epainassist.com]
The ESR was 2 mm/1st h and CRP was 20.5 mg/l after the end of treatment. [ard.bmj.com]
Prognosis
The prognosis is good for febrile neutropenic patients with underlying leukemia or lymphoma when the neutropenia resolves. [ncbi.nlm.nih.gov]
Prognosis among the immunocompromised, those with underlying lung disease, those in hospital, the elderly and the very young is variable but tends to be worse. [patient.info]
It is noted that the prognosis for Moraxella Catarrhalis is pretty good if the infection is detected early. Usually with 5-7 days of antibiotic treatment, the infection clears off. [epainassist.com]
Etiology
Multibacterial etiology was seen in 34 (38%) samples, and M. catarrhalis was detected in most (85%) of those cases. Fifteen signals for M. catarrhalis were strong, suggesting a highly probable etiological role of the pathogen. [ncbi.nlm.nih.gov]
To our knowledge, Moraxella species have been reported as the etiologic agent in three cases [jamanetwork.com]
Epidemiology
ISSN: 0950-2688 EISSN: 1469-4409 URL: /core/journals/epidemiology-and-infection [cambridge.org]
Author information 1 Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. 2 Milken Institute School of Public Health, Department of Epidemiology and Biostatistics [ncbi.nlm.nih.gov]
Pathophysiology
The case presented suggests the pathophysiology of this rare condition. One previous case of septic arthritis caused by M. catarrhalis without documented bacteremia has been reported. [ncbi.nlm.nih.gov]
The case presented suggests the pathophysiology ofthis rare condition. One previous case of septic arthritis caused by M. catarrhalis without documented bacteremia has been reported. [academic.oup.com]
Pathophysiology and Etiology Studies have shown that M catarrhalis colonizes the upper respiratory tract in 28-100% of humans in the first year of life. In adults, the colonization rate is 1-10.4%. [emedicine.medscape.com]
Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases. Am J Physiol Lung Cell Mol Physiol 2003;284:L566–L577. Richman-Eisenstat JB, Jorens PG, Hebert CA, Ueki I, Nadel JA. [erj.ersjournals.com]
Prevention
A vaccine to prevent M. catarrhalis infections would have an enormous impact globally in preventing morbidity caused by M. catarrhalis in these populations. [ncbi.nlm.nih.gov]