Presentation
We present a case of a healthy gravid individual who presented with chorioamnionitis and neonatal seizures associated with M. morganii. This organism, which causes severe morbidity, is fortunately rare in obstetrics and gynecology. [ncbi.nlm.nih.gov]
Entire Body System
- Anemia
We present here a case of non-drug-induced sulfhemoglobinemia in a 7-day-old preterm infant complicated by hemolytic anemia. [ncbi.nlm.nih.gov]
- Intermittent Fever
However, she was readmitted due to intermittent fever. The result of blood culture obtained before surgery disclosed M. morganii, which was resistant to clindamycin and cefazolin. Her symptoms resolved after administration of intravenous flomoxef. [ncbi.nlm.nih.gov]
Gastrointestinal
- Abdominal Guarding
She was febrile (38°C), had involuntary abdominal guarding and rebound tenderness on physical examination. Dialysate white blood cell count was 1100/mm3 (79% neutrophils). [revistanefrologia.com]
- Lower Abdominal Pain
A 54-year-old menopausal woman visited the emergency room with lower abdominal pain, vomiting, and fever for 4 days. Pelvic examination revealed lifting tenderness over the right adnexum without motion tenderness of the uterus. [ncbi.nlm.nih.gov]
Musculoskeletal
- Knee Effusion
M morganii was also isolated sedimentafrom the exudate of a diabetic ulcer in the left foot, with antibiotic susceptibilities identical to those from the knee effusion. [ncbi.nlm.nih.gov]
- Joint Effusion
Septic arthritis should be considered as a possible diagnosis in all elderly patients with joint effusions. [ncbi.nlm.nih.gov]
Eyes
- Lacrimation
During careful intraoperative examination the abscess was seen to directly extend from the lacrimal sac. Cultures were taken and grew Morganella morganii, a Gram negative rod uncommon in ocular and periocular infections. [ncbi.nlm.nih.gov]
- Corneal Infiltrate
A 52-year-old female patient presented with marked bilateral corneal infiltration and hypopyon without any usual predisposing factors for bilateral infectious keratitis. [ncbi.nlm.nih.gov]
Skin
- Skin Lesion
The presence of organisms in the bullae, demonstrated by Gram strain and culture, and the acral location of the bullae suggest that the skin lesions were due directly to blood-borne infection. [ncbi.nlm.nih.gov]
- Dermatitis
Topical corticosteroid-induced rosacea-like dermatitis was diagnosed by dermatologist because of the characteristic eruptions and long history of using the corticosteroids-containing cosmetic creams on her face. [ncbi.nlm.nih.gov]
Neurologic
- Neonatal Seizures
We present a case of a healthy gravid individual who presented with chorioamnionitis and neonatal seizures associated with M. morganii. This organism, which causes severe morbidity, is fortunately rare in obstetrics and gynecology. [ncbi.nlm.nih.gov]
Reports involving M. morganii infections in immunocompromised individuals include chorioamnionitis and neonatal seizures in a pregnant woman ( 51 ), a postoperative foot infection in a diabetic ( 37 ), and pyomyositis ( 1a ) and meningitis ( 63a ) in [doi.org]
Treatment
The mother responded to treatment with ampicillin, metronidazole, and gentamicin following delivery and had an uncomplicated recovery. [ncbi.nlm.nih.gov]
As in the cold shock treatment, heat shock treatment under the conditions tested did not affect the susceptibility of M. morganii to NaCl and low pH. [onlinelibrary.wiley.com]
Prognosis
This study heralds in a need for more research in this area as infections caused by these two pathogens are on the rise.Moreover,resistance to antimicrobials is also an increasingly common problem thus delaying the treatment and prognosis of disease. [physiciansweekly.com]
Prognosis The prognosis depends on the type of infection and the particular host. Data suggest that inappropriate antimicrobials (ones that an organism is resistant to) are associated with a worse outcome. Tucci V, Isenberg HD. [emedicine.medscape.com]
Etiology
Currently, there are no known reported cases in the literature of M. morganii as an etiologic pathogen for a postoperative foot infection. [ncbi.nlm.nih.gov]
In 1906 Morgan isolated, from the stools of infants with "summer diarrhea," a previously undescribed gram-negative bacterium, Morgan's bacillus No. 1, which he considered of possible etiologic significance. [doi.org]
Presenting signs, etiology, bacteriology and localisation. Acta Paediatr Scand. 1983 Nov. 72(6):879-83. [Medline]. Casanova-Roman M, Sanchez-Porto A, Casanova-Bellido M. [emedicine.medscape.com]
Epidemiology
Infection Control & Hospital Epidemiology ISSN: 0899-823X EISSN: 1559-6834 URL: /core/journals/infection-control-and-hospital-epidemiology Cited by 29 Crossref Citations This article has been cited by the following publications. [cambridge.org]
In this review, we summarized the epidemiology of M. morganii, particularly on its resistance profile and resistant genes, as well as the disease spectrum and risk factors for its infection. Copyright © 2016 The Author(s). [ncbi.nlm.nih.gov]
Samonis Clinical and Epidemiological Study Abstract Background: Morganella morganii is a commensal Gram-negative bacillus of the intestinal tract of humans and other mammals and reptiles. [doi.org]
Pathophysiology
Diagnosis requires a high index of suspicion and imaging tests. [3] Pathophysiology M morganii has been associated with urinary tract infections, sepsis, pneumonia, wound infections, musculoskeletal infections, CNS infections, pericarditis, chorioamnionitis [emedicine.medscape.com]
Prevention
Hence, F. ulmaria exhibits inhibitory activity against bacterial HDC and might be effective for preventing food poisoning caused by histamine. Received: July 19, 2015; Accepted: November 11, 2015; [jfoodprotection.org]
Hence, F. ulmaria exhibits inhibitory activity against bacterial HDC and might be effective for preventing food poisoning caused by histamine. [meridian.allenpress.com]
Early diagnosis, treatment, and active surveillance play an important role in prevention of complications. [woundsresearch.com]
In order to prevent phage resistance from happening, one way was to apply phage cocktail to repress the development of resistance. [microbewiki.kenyon.edu]
To prevent this phenomenon, confirmed M. morganii sepsis should be treated with a combination of third-generation cephalosporin and aminoglycoside. [19,22,29]. Conclusion M. morganii is a rare cause of neonatal sepsis and meningitis. [jscholaronline.org]