Presentation
Abstract The present case is that of a 27 years old woman who had received right oophorectomy for ovarian cancer nine years previously. The histological diagnosis at that time was mucinous cystadenocarcinoma with anaplastic areas. [ncbi.nlm.nih.gov]
Case presentation The authors describe a 57-year-old Brazilian woman who presented with an increase in abdominal girth in February 2003. Imaging studies showed a giant abdominal pelvic mass with probable origin in the right ovary. [jmedicalcasereports.biomedcentral.com]
Breast
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Nipple Discharge
A 30-year-old woman presents with nipple discharge of 3 weeks in duration. Physical examination reveals a white dis- charge from both nipples. The patient has not menstruated for the past 4 months, and she is not pregnant. [quizlet.com]
Urogenital
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Adnexal Mass
MD-Medical Data 2014;6(1): 023-027 Originalni lanci/ Original More information MR diagnostics of adnexal masses MR diagnostics of adnexal masses Poster No.: C-1499 Congress: ECR 2017 Type: Educational Exhibit Authors: O. Nikolic, J. Ostojic, M. [healthdocbox.com]
Most of sonographically indeterminate adnexal masses turn out to be common benign entities that can be readily diagnosed by magnetic resonance imaging. [link.springer.com]
B and C, bilateral adnexal masses (arrow), omental caking, diffuse disease with peritoneal involvement including the diaphragmatic surface and liver capsule, and an inflamed appendix (asterisk) secreting mucinous material (triangles). [jaoa.org]
Ultrasound typically large cystic adnexal mass multilocular with numerous thin septations loculations may contain low-level internal echogenicity due to increased mucin content different locules may contain various degrees of echogenicity MRI Mucinous [radiopaedia.org]
Subjective assessment of adnexal masses with the use of ultrasonography: an analysis of interobserver variability and experience. Ultrasound Obstet Gynecol 1999;13:11–16. 2. Valentin L. [e-ultrasonography.org]
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Pelvic Pain
Case Report A 27-year-old unmarried female presented with complaints of right-sided pelvic pain and a sensation of fullness in her lower abdomen. [cjhr.org]
In such cases, the signs and symptoms associated with the accompanying syndrome may exist Following are the common signs and symptoms associated with this tumor type: Abdominal pain (the pain is usually a pelvic pain) Abdominal swelling due to the mass [dovemed.com]
It affects women during the reproductive years and may cause chronic pelvic pain associated with menstruation. The ovaries are involved in approximately 75% of patients with endometriosis. [radiologyassistant.nl]
Physical examination shows no abnormal vaginal discharge or evidence of pelvic pain but does reveal redness on the lower side of the left breast. [quizlet.com]
Most of these tumors are asymptomatic; the most common symptoms are abdominal mass, abdominal and/or pelvic pain, and infertility, many are discovered during abdominal or pelvic surgery for other pathology. [glowm.com]
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Dyspareunia
[…] such as constipation Feeling full soon after eating less (having a feeling of satiety after eating less) Loss of appetite Weight loss Fatigue, feeling tired easily Frequent urination (polyuria) and difficulty while urinating Frequent pain during sex (dyspareunia [dovemed.com]
Patients with ovarian tumors occasionally complain of dyspareunia, infertility, and urinary frequency. [glowm.com]
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Enlarged Uterus
Gynecologic examination reveals an enlarged uterus. The hysterectomy specimen shows a large polypoid mass involving the endometrium and myometrium. [quizlet.com]
Workup
Physical examination and careful systemic workup were negative. The diagnosis of a (primary) skin mucinous carcinoma was confirmed. KEYWORDS – Adenocarcinoma, mucinous. [revista.spdv.com.pt]
On top of the renal amyloidosis his medical workup revealed presence of sensorineural hearing loss (up to 30 dB in frequency of 6,000 Hz). Within 2 days of anakinra therapy all his systemic features disappeared. [frontiersin.org]
Serum
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Dyslipidemia
She underwent an appendectomy and cholecystectomy, respectively, at the ages of 16 and 29, and had arterial hypertension and dyslipidemia. She denied the use of tobacco, alcohol or illicit drugs. [jmedicalcasereports.biomedcentral.com]
Ultrasound
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Ovarian Mass
Figure 1: Above (a) intraoperative picture of ovarian mass. (b) Postoperative ovarian mass and excised omentum. (c) Ultrasound shows ovarian mass with both solid, cystic components and loculations with thin-walled septa. [ccij-online.org]
Intraoperatively a left sided huge ovarian mass of variable consistency with intact capsule, with no surface growth was found. There was no evidence of ascites or metastasis to peritoneum or paraaortic or pelvic lymph nodes. [jpgo.org]
mass with vascularization in some of the septations Benign cystic lesions: Mucinous cystadenoma with a septated cystic ovarian mass Benign cystic lesions: Mucinous cysteadenoma Benign cystic lesions: Mucinous cysteadenoma Benign cystic lesions: Mucinous [ultrasoundcases.info]
Discussion Giant ovarian masses are extremely rare. [cancerjournal.net]
It includes a standardized methodology for the US evaluation of ovarian masses and definitions of the ultrasonographic parameters of ovarian masses [ 6, 8, 9 ]. [e-ultrasonography.org]
Treatment
The survival rate of patients with advanced-stage mucinous cystadenocarcinoma of the ovary is dismal and no best treatment is known. [ncbi.nlm.nih.gov]
Mucinous epithelial ovarian cancer: A separate entity requiring specific treatment. J Clin Oncol 2004;22:1040-4. 6. Guruprasad B, Jacob LA. Mucinous cystadenocarcinoma of ovary: Changing treatment paradigms. World J Obstet Gynecol 2012;10:42-5. 7. [ccij-online.org]
CONCLUSION In the past the standard treatment for all advanced stage epithelial ovarian cancer was cytoreductive surgery followed by standard postoperative treatment with platinum based chemotherapy. [wjgnet.com]
The primary treatment for early stage mucinous neoplasm is surgical (total abdominal hysterectomy, bilateral salpingo-oophorectomy, and surgical staging as with serous tumors). [jpgo.org]
What will you tell the family about risks/benefits of the available treatment options Table III. [cancertherapyadvisor.com]
Prognosis
The prognosis was related to the most aggressive area of the tumor as the histologic grade was based on the maximum number of mitoses per high-powered field. [ncbi.nlm.nih.gov]
In early stage ovarian cancer, systematic lymph node dissection is required for meticulous staging, which is helpful for adjuvant treatment planning and to explain prognosis. [ccij-online.org]
Etiology
Abstract To elucidate the genetic etiology of sporadic epithelial ovarian carcinoma, we examined replication errors (RER) in its two common types, serous cystadenocarcinoma (SAC) and mucinous cystadenocarcinoma (MAC). [ncbi.nlm.nih.gov]
Etiology Thought to largely derive from ovarian epithelial inclusions, which itself is derived from fallopian tube epithelium. Location They can be bilateral in 15% of cases. [radiopaedia.org]
Cell. vol. 140. 2010. pp. 784(A review of current thinking about the etiology of autoinflammatory diseases and recent advances that offer new opportunities for therapeutic intervention.) Ombrello, MJ, Kastner, DL. [cancertherapyadvisor.com]
Etiology MWS is due to dominant mutation in the NLRP3 (1q44) gene which encodes cryopyrin. [orpha.net]
Causes Of Ovarian Mucinous Cystadenoma The etiology of benign mucinous cystadenoma of ovary is not fully understood. These tumors develop spontaneously. [tandurust.com]
Epidemiology
Angiology (103) Gastroenterology and Hepatology (98) Microbiology (82) Endocrinology, Metabolism (79) Haematology (76) Oncology, Radiation Therapy (75) Neurosurgery (70) Psychiatry, Psychology, Sexology (69) Obstetrics, Gynaecology (64) Nephrology (63) Epidemiology [portal.mefanet.cz]
Summary Epidemiology The prevalence of MWS is unknown. However a French survey through genetic laboratories has reported 135 cases and estimated CAPS prevalence at 1/360,000. [orpha.net]
Mutations in the autoinflammatory cryopyrin-associated periodic syndrome gene: epidemiological study and lessons from eight years of genetic analysis in France. Ann Rheum Dis. 2011;70(3):495–499. 2. [dovepress.com]
Genetic epidemiological studies of early-onset deafness in the US school-age population. Am J Med Genet 1993;46:486-91. Morton NE. Genetic epidemiology of hearing impairment. Ann N Y Acad Sci 1991;630:16-31. Davis A, Parving A. [kjorl.org]
Pathophysiology
Paediatrics, Neonatology (387) Internal Medicine (386) Pathology and Forensic Medicine (274) Neurology (261) Physiology and Pathophysiology (242) Genetics (224) Surgery, Traumatology and Orthopaedics (183) Medical Chemistry and Biochemistry (174) Infectology [portal.mefanet.cz]
In: Pharmacotherapy: A pathophysiologic approach.8th ed. Dipiro JT, Talbert RL, Yee GC et al., New York: McGraw-Hill; 2008: 2361-75. [en.wikipedia.org]
Progressively, they could develop various psychological problems such as drug addictions or severe depression leading to suicide.10 Understanding CAPS pathophysiology has allowed efficacious treatment targeting IL-1β. [dovepress.com]
Pharmacotherapy: A pathophysiologic approach 2361-2375. GorgoneS, MinnitiC, IlaquaA, BarbusciaM (2008) Giant mucinous cystadenoma in a young patient. A Case Report g Chir 29: 42-44. [omicsonline.org]
Sudden death in nondilated cardiomyopathies: pathophysiology and prevention. Curr Heart Fail Rep. 2005 Sep. 2(3):118-23. [Medline]. Palladini G, Perfetti V, Obici L, Caccialanza R, Semino A, Adami F. [medscape.com]
Prevention
Mucinous Cystadenoma Prevention and Treatment Mucinous Cystadenoma usually do not shrink by themselves they may remain as non- interfering in some cases. Smaller sized cystadenomas can be removed by laparoscopic method. [mucinous.org]
It is too soon to tell if early medication treatment for MWS or NOMID/CINCA will prevent or decrease the development of hearing loss, but there is great hope that it will make a significant difference. [autoinflammatory.org]
Rapid sequence induction and intubation would, therefore, be required to prevent acid aspiration syndrome. All the above mentioned concerns were addressed in the anesthetic plan formulated for the present patient. [karnatakaanaesthj.org]
Gastroenterology and Hepatology (98) Microbiology (82) Endocrinology, Metabolism (79) Haematology (76) Oncology, Radiation Therapy (75) Neurosurgery (70) Psychiatry, Psychology, Sexology (69) Obstetrics, Gynaecology (64) Nephrology (63) Epidemiology, Preventive [portal.mefanet.cz]