Case presentation The authors describe a 57-year-old Brazilian woman who presented with an increase in abdominal girth in February 2003. Imaging studies showed a giant abdominal pelvic mass with probable origin in the right ovary. [jmedicalcasereports.biomedcentral.com]

Abstract The present case is that of a 27 years old woman who had received right oophorectomy for ovarian cancer nine years previously. The histological diagnosis at that time was mucinous cystadenocarcinoma with anaplastic areas. [ncbi.nlm.nih.gov]

• Ascites

  Abstract Rabbit antiserum to a tissue extract of human mucinous cystadenocarcinoma of the ovary reacted with tissue extracts of normal ovary and various ovarian malignancies, and ascitic or cystic fluids of ovarian origin by Ouchterlony double gel diffusion [ncbi.nlm.nih.gov]

  D, ascitic fluid demonstrates bland mucinous columnar epithelial cells with low-grade nuclei, arranged in strips, sheets, and nests, in the background of abundant mucin, also seen in the cell block (inset). [jaoa.org]

  On the contrary, Pseudo- Meigs syndrome is characterized by the co-existence of hydrothorax, ascites and ovarian tumor either benign or malignant other than ovarian fibroma. [banglajol.info]

  There is no ascites orperitoneal deposits and no lymphadenopathy. At pathology this was a mucinous cystadenocarcinoma of low malignant potential. [radiologyassistant.nl]

• Asymptomatic

  In conclusion, this case proves that huge asymptomatic Brenner's tumors still occur in patients. Proper histological examination of the surgically removed specimens is essential to confirm the diagnosis. [cancerjournal.net]

  Under follow-up for more than 10 years, she is asymptomatic and with normal imaging and laboratory parameters, including the cancer antigen-125 marker. [jmedicalcasereports.biomedcentral.com]

  Generally asymptomatic. If symptoms are present, they are usually related to mass effect with displacement of adjacent structures, e.g. loops of bowel, adnexal torsion. [radiopaedia.org]

  Symptoms Of Mucinous Cystadenoma In Ovary Many cases of benign mucinous cystadenoma of ovary remain asymptomatic. The growth of tumor is slow. Normally only one ovary is affected. Sometime the disease is bilateral. [tandurust.com]

  Cold as a trigger for attacks, frequent headaches and asymptomatic papilloedema (swelling at the back of the eye) are examples. [dermnetnz.org]

• Swelling

  They are usually asymptomatic and the patient presents with abdominal swelling because of its size. [ispub.com]

  Cold as a trigger for attacks, frequent headaches and asymptomatic papilloedema (swelling at the back of the eye) are examples. [dermnetnz.org]

  The case herein concerns a 70 year old postmenopausal woman presented with the complaints of progressive shortness of breath on exertion and progressive swelling of lower abdomen. [banglajol.info]

  In both cases, the women described a progressive infraumbilical swelling and abdominal pain [ 14 ]. [jmedicalcasereports.biomedcentral.com]

  The lesions become more pruritic with swelling and erythema when rubbed. [quizlet.com]

• Anemia

  Other blood tests could be taken and analyzed as well to see if a patient has leukocytosis (an increase in the number of white cells in the blood), anemia (a deficiency of red blood cells or hemoglobin in the blood), an elevated C-reactive protein level [raregenomics.org]

  […] mouth [ more ] 0000174 Abnormality of the genital system Genital abnormalities Genital abnormality Genital anomalies Genital defects [ more ] 0000078 Abnormality of the nose Nasal abnormality 0000366 Abnormality of the voice Voice abnormality 0001608 Anemia [rarediseases.info.nih.gov]

  Other complications associated with teratoma are infection, rupture (spontaneous or trauma) and, rarely, hemolytic anemia (resolves with resection). [radiologyassistant.nl]

  A CBC reveals a hypochromic, microcytic anemia (hemoglobin = 8 g/dL). Bimanual pelvic examination reveals an enlarged uterus with multiple, irregular masses. [quizlet.com]

• Surgical Procedure

  The normal surgical procedure to treat patients suffering from mucinous ovarian cancer is to remove the uterus, ovaries and fallopian tubes. [omicsonline.org]

  The treatment for Mucinous Adenocarcinoma of Ovary may include a combination of chemotherapy (drugs), radiation therapy, and surgical procedures that are employed by the healthcare provider to treat the condition. [dovemed.com]

• Pleural Effusion

  Her clinical and radiological examination revealed a massive right sided pleural effusion, mild ascites and a large heterogeneous pelvic mass with solid and cystic components, suggestive of left ovarian tumor. [banglajol.info]

  There was mild ascites along with mild bilateral pleural effusion. The levels of serum cancer antigen 125 (CA-125), serum lactate dehydrogenase (LDH), and alpha fetoprotein were 179.4 U/ml, 715.9 IU/L, and 0.96 ng/ml, respectively. [ccij-online.org]

  She also had moderate pelvic ascites, and right pleural effusions. Things were really bad. Moffitt was doing everything to find a "secondary primary" as the new source of this cancer. [inspire.com]

  Chest X-ray showed blunting of the right-sided costophrenic angle suggestive of mild pleural effusion. [karnatakaanaesthj.org]

  Both ovaries may demonstrate cystic enlargement with ascites or pleural effusion ( Fig. 13 ) [ 35, 36 ]. [e-ultrasonography.org]

• Respiratory Distress

  Case report An 11-year-old premenopausal girl presented with 3 months history of abdominal distension and respiratory distress. [ccij-online.org]

  Wittkowski H, Sturrock A, van Zoelen MA, Viemann D, van der Poll T, Hoidal JR, Roth J, Foell D: Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome. [arthritis-research.biomedcentral.com]

• Dyspnea

  Immunofluorescent staining of skin with anti-IgG For the past 3 days, a 25-year-old man known to be infected with HIV has had increasing fever, cough, and dyspnea, which has culminated in acute respiratory failure. [quizlet.com]

• Abdominal Pain

  Patient was admitted in our hospital with abdominal pain of one-month duration. On abdominal ultrasound, a huge heterogeneous mass was found to encompass the whole abdomen. [cancerjournal.net]

  In both cases, the women described a progressive infraumbilical swelling and abdominal pain [ 14 ]. [jmedicalcasereports.biomedcentral.com]

  pain Benign cystic lesions: Ruptured hemorrhagic follicle cyst with a small effusion Benign cystic lesions: Hemorrhagic ovarian cyst with sedimentation of the hemorrhagic contents A 6 mm thick appendix was found without signs of inflammation. [ultrasoundcases.info]

  Additional features include severe chronic fatigue, recurrent headaches, cognitive impairment, ocular involvement (conjunctivitis, uveitis, episcleritis), oral aphthosis, lymphadenopathy, thoracic and abdominal pain. [orpha.net]

  As with other forms of this syndrome, it presents with recurrent episodes of fever, skin rash, joint pain, abdominal pain and conjunctivitis, but in addition sufferers typically develop a progressive sensorineural deafness and amyloidosis. [dermnetnz.org]

• Abdominal Mass

  Although this tumour is rare, this diagnosis should be considered in 11 to 15-year-old girls presenting with a very large abdominal mass. [link.springer.com]

  She presented with pain in abdomen and abdominal mass of 34 weeks size. Ultrasound revealed multiloculated large ovarian cyst, Staging laparotomy and left side salphingoophorectomy was done. [jpgo.org]

  Cystadenocarcinoma This middle aged female patient presented with abdominal mass extending from pelvis to above the umbilical region. On sonography there was a complex mass having both solid and cystic components extending upwards from the pelvis. [ultrasound-images.com]

  On physical examination, a large abdominal mass was palpable predominantly on left side extending above the umbilical region. Ultrasound (USG) examination shows ovarian mass (12.5 cm × 11 cm × 7 cm) with both solid and cystic components. [ccij-online.org]

  She had an intra-abdominal mass of 26 weeks size, which was mobile and tender. There was no evidence of ascitis. Examination of the genitalia showed a normal vulva with an intact hymen for which a digital vaginal examination was suspended. [ispub.com]

• Pelvic Mass

  Her clinical and radiological examination revealed a massive right sided pleural effusion, mild ascites and a large heterogeneous pelvic mass with solid and cystic components, suggestive of left ovarian tumor. [banglajol.info]

  Top Magn Reson Imaging 14:305–327 CrossRef Google Scholar Saksouk FA, Johnson SC (2004) Recognition of the ovarian origin of pelvic masses with CT. [link.springer.com]

  Imaging studies showed a giant abdominal pelvic mass with probable origin in the right ovary. Cancer antigen-125 was elevated, while carcinoembrionic antigen and alpha-fetoprotein were normal. [jmedicalcasereports.biomedcentral.com]

  Cystourethrogram showed a urinary bladder with extrinsic pressure effect superiorly due to a pelvic mass. A diagnosis of a right ovarian mass was made. The patient was counselled and prepared for surgery. Informed consent was obtained. [ispub.com]

  Pattern recognition of pelvic masses by gray-scale ultrasound imaging: the contribution of Doppler ultrasound. Ultrasound Obstet Gynecol 1999;14:338–347. 4. Brown DL, Dudiak KM, Laing FC. Adnexal masses: US characterization and reporting. [e-ultrasonography.org]

• Abdominal Distension

  Case report An 11-year-old premenopausal girl presented with 3 months history of abdominal distension and respiratory distress. [ccij-online.org]

  All children presented with marked abdominal distension and discomfort. Except for one child who had ultrasound scan alone, all the others had either CT or MRI scan as well. [link.springer.com]

  This patient presented with increasing abdominal distension with no pressure symptoms. Modern methods of investigation particularly ultrasonography can identify the nature of the tissue as in this case. [ispub.com]

  Case Report A 37-year-old lady presented with gross abdominal distension that had progressively worsened over the past 8 months. [karnatakaanaesthj.org]

• Peritoneal Disease

  Peritoneal Implants Serous borderline tumors have a disconcertingly high frequency of extraovarian disease. [nature.com]

• Jaundice

  She was neither pale, febrile to torch or jaundiced. She had an intra-abdominal mass of 26 weeks size, which was mobile and tender. There was no evidence of ascitis. [ispub.com]

  There was no pallor, jaundice, edema or lymphadenopathy. Cardiac and chest examinations were unremarkable. Abdomen was grossly distended by a pelvi-abdominal mass corresponding to the size of a 36 weeks pregnant uterus by palpation. [cancerjournal.net]

• Neglect

  These huge neglected masses can mimic other medical conditions on clinical examination, such as pregnancy, massive ascites and colonic volvulus. [12] Surgical management is the usual way to manage these patients. [cancerjournal.net]

• Adnexal Mass

  B and C, bilateral adnexal masses (arrow), omental caking, diffuse disease with peritoneal involvement including the diaphragmatic surface and liver capsule, and an inflamed appendix (asterisk) secreting mucinous material (triangles). [jaoa.org]

  MD-Medical Data 2014;6(1): 023-027 Originalni ~lanci/ Original More information MR diagnostics of adnexal masses MR diagnostics of adnexal masses Poster No.: C-1499 Congress: ECR 2017 Type: Educational Exhibit Authors: O. Nikolic, J. Ostojic, M. [healthdocbox.com]

  Most of sonographically indeterminate adnexal masses turn out to be common benign entities that can be readily diagnosed by magnetic resonance imaging. [link.springer.com]

  Ultrasound typically large cystic adnexal mass multilocular with numerous thin septations loculations may contain low-level internal echogenicity due to increased mucin content different locules may contain various degrees of echogenicity MRI Mucinous [radiopaedia.org]

  Pattern recognition of pelvic masses by gray-scale ultrasound imaging: the contribution of Doppler ultrasound. Ultrasound Obstet Gynecol 1999;14:338–347. 4. Brown DL, Dudiak KM, Laing FC. Adnexal masses: US characterization and reporting. [e-ultrasonography.org]

• Pelvic Pain

  Case Report A 27-year-old unmarried female presented with complaints of right-sided pelvic pain and a sensation of fullness in her lower abdomen. [cjhr.org]

  In such cases, the signs and symptoms associated with the accompanying syndrome may exist Following are the common signs and symptoms associated with this tumor type: Abdominal pain (the pain is usually a pelvic pain) Abdominal swelling due to the mass [dovemed.com]

  It affects women during the reproductive years and may cause chronic pelvic pain associated with menstruation. The ovaries are involved in approximately 75% of patients with endometriosis. [radiologyassistant.nl]

  Physical examination shows no abnormal vaginal discharge or evidence of pelvic pain but does reveal redness on the lower side of the left breast. [quizlet.com]

  Most of these tumors are asymptomatic; the most common symptoms are abdominal mass, abdominal and/or pelvic pain, and infertility, many are discovered during abdominal or pelvic surgery for other pathology. [glowm.com]

• Mass of Ovary

  Ultrasound demonstrated a large multiloculated cystic mass arising from the pelvis reaching the level of the xiphoid. CT demonstrated an enormous mass occupying almost the entire abdomen. [link.springer.com]

Physical examination and careful systemic workup were negative. The diagnosis of a (primary) skin mucinous carcinoma was confirmed. KEYWORDS – Adenocarcinoma, mucinous. [revista.spdv.com.pt]

On top of the renal amyloidosis his medical workup revealed presence of sensorineural hearing loss (up to 30 dB in frequency of 6,000 Hz). Within 2 days of anakinra therapy all his systemic features disappeared. [frontiersin.org]

• Ovarian Mass

  […] benign ovarian cyst Benign cystic lesions: Multiloculated cystic ovarian mass with a vascularized mass. [ultrasoundcases.info]

  Figure 1: Above (a) intraoperative picture of ovarian mass. (b) Postoperative ovarian mass and excised omentum. (c) Ultrasound shows ovarian mass with both solid, cystic components and loculations with thin-walled septa. [ccij-online.org]

  Macroscopically the ovarian mass measured 35 x 20 cm, weighed 4.5 kg. On cut section the mass was multiloculated with mucinous fluid of 4 liters with some solid components (figure 2). Figure 2. Gross appearance of the tumor. [jpgo.org]

  No ovarian mass of such weight has been ever reported in our hospital before, and it is one of the largest ovarian masses reported in the literature in Egypt. > References 1. Chen VW, Ruiz B, Killeen JL, Cote TR, Wu XC, Correa CN. [cancerjournal.net]

  It includes a standardized methodology for the US evaluation of ovarian masses and definitions of the ultrasonographic parameters of ovarian masses [ 6, 8, 9 ]. [e-ultrasonography.org]

• Multilocular Cyst

  […] cystadenomas are usually seen as large multilocular cysts containing fluid of various viscosity. [radiopaedia.org]

  […] as multilocular cyst. [e-ultrasonography.org]

  Grossly, the outer surface of mass was smooth with intact capsule and cut surface having multilocular cyst with solid areas [Figure 1]. The cyst contained mucinous material. [ccij-online.org]

  cysts with smooth surfaces. [emedicine.medscape.com]

• Pleural Effusion

  Her clinical and radiological examination revealed a massive right sided pleural effusion, mild ascites and a large heterogeneous pelvic mass with solid and cystic components, suggestive of left ovarian tumor. [banglajol.info]

  There was mild ascites along with mild bilateral pleural effusion. The levels of serum cancer antigen 125 (CA-125), serum lactate dehydrogenase (LDH), and alpha fetoprotein were 179.4 U/ml, 715.9 IU/L, and 0.96 ng/ml, respectively. [ccij-online.org]

  She also had moderate pelvic ascites, and right pleural effusions. Things were really bad. Moffitt was doing everything to find a "secondary primary" as the new source of this cancer. [inspire.com]

  Chest X-ray showed blunting of the right-sided costophrenic angle suggestive of mild pleural effusion. [karnatakaanaesthj.org]

  Both ovaries may demonstrate cystic enlargement with ascites or pleural effusion ( Fig. 13 ) [ 35, 36 ]. [e-ultrasonography.org]

Mucinous epithelial ovarian cancer: A separate entity requiring specific treatment. J Clin Oncol 2004;22:1040-4. 6. Guruprasad B, Jacob LA. Mucinous cystadenocarcinoma of ovary: Changing treatment paradigms. World J Obstet Gynecol 2012;10:42-5. 7. [ccij-online.org]

Mucinous cystadenocarcinoma of ovary: Changing treatment paradigms. [wjgnet.com]

What will you tell the family about risks/benefits of the available treatment options Table III. [cancertherapyadvisor.com]

The survival rate of patients with advanced-stage mucinous cystadenocarcinoma of the ovary is dismal and no best treatment is known. [ncbi.nlm.nih.gov]

Two interleukin-1 antagonists have FDA approval for the treatment of Muckle–Wells syndrome. Rilonacept has been approved for the treatment of MWS for adults and children from the age of 12 years. [dermnetnz.org]

The prognosis was related to the most aggressive area of the tumor as the histologic grade was based on the maximum number of mitoses per high-powered field. [ncbi.nlm.nih.gov]

In patients with stage II-IV disease, the prognosis is different; an increased stage is associated with a worse prognosis and only age at diagnosis and the presence of invasive implants are shown to influence prognosis. [emedicine.medscape.com]

Abstract To elucidate the genetic etiology of sporadic epithelial ovarian carcinoma, we examined replication errors (RER) in its two common types, serous cystadenocarcinoma (SAC) and mucinous cystadenocarcinoma (MAC). [ncbi.nlm.nih.gov]

Cell. vol. 140. 2010. pp. 784(A review of current thinking about the etiology of autoinflammatory diseases and recent advances that offer new opportunities for therapeutic intervention.) Ombrello, MJ, Kastner, DL. [cancertherapyadvisor.com]

Etiology Thought to largely derive from ovarian epithelial inclusions, which itself is derived from fallopian tube epithelium. Location They can be bilateral in ~15% of cases. [radiopaedia.org]

Etiology MWS is due to dominant mutation in the NLRP3 (1q44) gene which encodes cryopyrin. [orpha.net]

Causes Of Ovarian Mucinous Cystadenoma The etiology of benign mucinous cystadenoma of ovary is not fully understood. These tumors develop spontaneously. [tandurust.com]

Angiology (103) Gastroenterology and Hepatology (98) Microbiology (82) Endocrinology, Metabolism (79) Haematology (76) Oncology, Radiation Therapy (75) Neurosurgery (70) Psychiatry, Psychology, Sexology (69) Obstetrics, Gynaecology (64) Nephrology (63) Epidemiology [portal.mefanet.cz]

Summary Epidemiology The prevalence of MWS is unknown. However a French survey through genetic laboratories has reported 135 cases and estimated CAPS prevalence at 1/360,000. [orpha.net]

Mutations in the autoinflammatory cryopyrin-associated periodic syndrome gene: epidemiological study and lessons from eight years of genetic analysis in France. Ann Rheum Dis. 2011;70(3):495–499. 2. [dovepress.com]

Genetic epidemiological studies of early-onset deafness in the US school-age population. Am J Med Genet 1993;46:486-91. Morton NE. Genetic epidemiology of hearing impairment. Ann N Y Acad Sci 1991;630:16-31. Davis A, Parving A. [kjorl.org]

Paediatrics, Neonatology (387) Internal Medicine (386) Pathology and Forensic Medicine (274) Neurology (261) Physiology and Pathophysiology (242) Genetics (224) Surgery, Traumatology and Orthopaedics (183) Medical Chemistry and Biochemistry (174) Infectology [portal.mefanet.cz]

In: Pharmacotherapy: A pathophysiologic approach.8th ed. Dipiro JT, Talbert RL, Yee GC et al., New York: McGraw-Hill; 2008: 2361-75. [en.wikipedia.org]

Progressively, they could develop various psychological problems such as drug addictions or severe depression leading to suicide.10 Understanding CAPS pathophysiology has allowed efficacious treatment targeting IL-1β. [dovepress.com]

Pharmacotherapy: A pathophysiologic approach 2361-2375. GorgoneS, MinnitiC, IlaquaA, BarbusciaM (2008) Giant mucinous cystadenoma in a young patient. A Case Report g Chir 29: 42-44. [omicsonline.org]

Sudden death in nondilated cardiomyopathies: pathophysiology and prevention. Curr Heart Fail Rep. 2005 Sep. 2(3):118-23. [Medline]. Palladini G, Perfetti V, Obici L, Caccialanza R, Semino A, Adami F. [medscape.com]

Mucinous Cystadenoma Prevention and Treatment Mucinous Cystadenoma usually do not shrink by themselves they may remain as non- interfering in some cases. Smaller sized cystadenomas can be removed by laparoscopic method. [mucinous.org]

It is too soon to tell if early medication treatment for MWS or NOMID/CINCA will prevent or decrease the development of hearing loss, but there is great hope that it will make a significant difference. [autoinflammatory.org]

Rapid sequence induction and intubation would, therefore, be required to prevent acid aspiration syndrome. All the above mentioned concerns were addressed in the anesthetic plan formulated for the present patient. [karnatakaanaesthj.org]

Gastroenterology and Hepatology (98) Microbiology (82) Endocrinology, Metabolism (79) Haematology (76) Oncology, Radiation Therapy (75) Neurosurgery (70) Psychiatry, Psychology, Sexology (69) Obstetrics, Gynaecology (64) Nephrology (63) Epidemiology, Preventive [portal.mefanet.cz]