More than 100 different subtypes have been described, with a wide range of clinical manifestations, presentations, and histologies. [scienceopen.com]

Xanthomatous lesions may also be present. The destructive osteoarthritis tends to be symmetrical and involves primarily the joints in the hands. The knees and wrists are also involved in greater than 50% of cases. [link.springer.com]

No iron, fat, or Touton or other giant cells were present. Ultrastructural study disclosed laminar bodies but no Langerhans' cells or Langerhans' granules. The process responded to low-dose intravenous vinblastine sulfate treatment. [jamanetwork.com]

PRESENTATION DE 2 CAS (fr) Author FRIEYRO SEGUI JE; MARTINEZ LOPEZ DE LETONA J; MASA VAZQUEZ C; PEREZ MAESTU R; ALAMO ANTUNEZ A; ALONSO ALONSO JJ; GUERRERO ESPEJO A; FRAILE DE ABAJO L UNIV. AUTON., FAC. MED., DEP. MED.,MADRID,ESP Source REV. CLIN. [pascal-francis.inist.fr]

[…] and prognosis Management is typically challenging and successful treatment regimens are only guided by case reports and series given the rarity of the condition 11. [radiopaedia.org]

The treatments used in these articles were critically analyzed and graded for their relative efficacy for skin and joint manifestations. [scienceopen.com]

The process responded to low-dose intravenous vinblastine sulfate treatment. (Arch Dermatol 1982;118:913-917) [jamanetwork.com]

Drug treatments Pascal 002 Biological and medical sciences / 002B Medical sciences / 002B08 Dermatology Pascal 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases Discipline Blood diseases Dermatology [pascal-francis.inist.fr]

Successful treatment of multicentric reticulohistiocytosis with alendronate. Arthritis & Rheumatism 48:3538-3541, 2003. Gorman et al. [med.upenn.edu]

[…] atlantoaxial involvement no or mild periarticular osteopenia (unlike rheumatoid arthritis) often a disproportion between severity of joint destruction and mildness of symptoms regardless of therapy absent or minimal periosteal reaction Treatment and prognosis [radiopaedia.org]

[…] reticulohistiocytosis without systemic involvement, and multicentric reticulohistiocytosis with identical light microscopic and ultrastructural findings suggests that these conditions probably represent a spectrum of clinical expressions of similar etiologic [jamanetwork.com]

Etiology and pathogenesis of necrolytic migratory erythema: review of the literature. Med Gen Med 2004; 6:4. Google Scholar Anhalt GJ, Kim SC, Stanley JR et al. Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia. [link.springer.com]

Paraneoplastic acral vascular syndrome: epidemiologic features, clinical manifestations, and disease sequelae. J Am Acad Dermatol 2002; 47:47–52. CrossRef PubMed Google Scholar Schwartz RA. Sign of Leser-Trelat. J Am Acad Dermatol 1996; 35:88–95. [link.springer.com]