No iron, fat, or Touton or other giant cells were present. Ultrastructural study disclosed laminar bodies but no Langerhans' cells or Langerhans' granules. The process responded to low-dose intravenous vinblastine sulfate treatment. [jamanetwork.com]

• Soft Tissue Swelling

  Features are bilateral and symmetric and include: sharply demarcated marginal erosions: can have a strikingly bilateral symmetrical distribution and is often sharply circumscribed and rapidly progressive nodular soft tissue swelling: may be appreciated [radiopaedia.org]

[…] and prognosis Management is typically challenging and successful treatment regimens are only guided by case reports and series given the rarity of the condition 11. [radiopaedia.org]

The process responded to low-dose intravenous vinblastine sulfate treatment. (Arch Dermatol 1982;118:913-917) [jamanetwork.com]

Successful treatment of multicentric reticulohistiocytosis with alendronate. Arthritis & Rheumatism 48:3538-3541, 2003. Gorman et al. [med.upenn.edu]

[…] atlantoaxial involvement no or mild periarticular osteopenia (unlike rheumatoid arthritis) often a disproportion between severity of joint destruction and mildness of symptoms regardless of therapy absent or minimal periosteal reaction Treatment and prognosis [radiopaedia.org]