Presentation
It may present early by direct invasion following initial infection, or late as a post infectious (ADEM) event. [adc.bmj.com]
Orchitis presents with high fevers (39-41°C), severe testicular pain accompanied by swelling, and erythema of the scrotum. Nausea, vomiting, and abdominal pain are often present. [reference.medscape.com]
In the present case, hydrocephalus, a condition which presents as a late complication of mumps [8], [14], was detected and treated at the early stages of the disease. [ijri.org]
I am presently interested in historical subjects including historical virology: see for example To Catch a Virus, Booss and August, ASM Press, 2013; and Neurovirology in the Elsevier series Handbook of Clinical Neurology, eds, Tselis and Booss, forthcoming [books.google.com]
Encephalitis and meningitis may exist together; one clinical presentation may predominate, or findings of both may be present (meningoencephalitis). Altered mental status is the key physical finding. [infectiousdiseaseadvisor.com]
Entire Body System
- High Fever
Call your doctor if your child has a high fever, especially if he or she also has a childhood illness (like measles, mumps, or chickenpox) or is recovering from one. [kidshealth.org]
On arrival, he was in a confused state with high fever and neck stiffness. There was no parotitis. Visual and auditory hallucinations were observed. There was no abnormality in the cerebral nerves except for a tongue tremor of 5∼6 Hz. [ajnr.org]
from having a high fever (about 1 out of every 3,000 doses) Temporary (short-term) low platelet count (about 1 out of every 30,000 doses) Like any medicine, there's a very small chance that the mumps vaccine could cause a serious reaction. [vaccines.gov]
Orchitis presents with high fevers (39-41°C), severe testicular pain accompanied by swelling, and erythema of the scrotum. Nausea, vomiting, and abdominal pain are often present. [reference.medscape.com]
Mumps has become an uncommon illness and is sometimes misdiagnosed with a high fever and swollen salivary glands that are actually indicative of tonsillitis [3]. [microbewiki.kenyon.edu]
- Infertility
Orchitis does not result in infertility for adolescents or adult men. Females could suffer from oophoritis and/or mastitis. [livestrong.com]
However, this is very rarely large enough to cause infertility. [nhs.uk]
[…] period – 12-25 days (average, 16-18 days) ( CDC, 2017) 25-30% of all infections are silent Most common clinical feature is bilateral or unilateral parotitis Secondary complications Orchitis – particularly in teenagers, can lead to decreased fertility or infertility [arupconsult.com]
Infection of the pancreas caused by the virus could lead to the development of juvenile diabetes, and infection of the testes and ovaries can lead to infertility. The initial symptoms of the mumps virus are similar to having a cold. [study.com]
Mumps Other names Epidemic parotitis Child with mumps Specialty Infectious disease Symptoms Fever, muscle pain, headache, feeling generally unwell, painful swelling of the parotid gland [1] Complications Meningitis, pancreatitis, deafness, infertility [en.wikipedia.org]
- Severe Pain
This disorder causes abdominal pain, severe nausea, and vomiting. These symptoms disappear in about a week, and the person recovers completely. [merckmanuals.com]
Severe pain (often requiring hospitalization for pain management ) was one-sided in most cases. Some affected testicles atrophied (decreased in size), and some demonstrated impaired fertility. The "common knowledge" of sterility was actually rare. [medicinenet.com]
Mumps orchitis is characterized by marked testicular swelling and severe pain, accompanied by fever, nausea, and headache ( 121 – 123 ). The pain and swelling resolve within 5 to 7 days, although residual testicular tenderness can persist for weeks. [oncohemakey.com]
- Anorexia
After this period, prodromal symptoms (such as low-grade fever, malaise, myalgias, headache, and anorexia) occur; these symptoms can last 3-5 days. [reference.medscape.com]
CLINICAL COURSE AND NATURAL HISTORY Mumps usually begins with a short prodromal phase characterized by low-grade fever, malaise, headache, and anorexia. Young children may initially complain of ear pain. [oncohemakey.com]
- Unconsciousness
On physical examination, the patient was unconscious, had neck stiffness, his temperature was 38°C, his blood pressure was normal; he had bilateral swellings in the parotid regions and findings of unilateral orchitis. [ijri.org]
Gastrointestinal
- Loss of Appetite
The symptoms of mumps include fever, headache, fatigue, loss of appetite and inflammation and tenderness of one or both salivary glands. The more serious and long-term side effects are described below. A Mother looking after her sick son. [livestrong.com]
Other symptoms of acute pancreatitis can include: feeling or being sick diarrhoea loss of appetite high temperature tenderness of the belly less commonly, yellowing of the skin and the whites of the eyes ( jaundice ) Although pancreatitis associated with [nhs.uk]
Others have a low-grade fever, headache, weakness, fatigue, and loss of appetite starting 14 to 24 days after they are actually infected. [medbroadcast.com]
Other possible symptoms can include fatigue, loss of appetite, and muscle aches. Source: MedicineNet What is mumps? Mumps is a vaccine-preventable viral infection transmitted by and affecting only humans. [medicinenet.com]
Early symptoms are uncommon but may include fever loss of appetite, achiness, and headache with a moderately high temperature, usually lasting for 3-4 days. [bu.edu]
- Lower Abdominal Pain
Symptoms include lower abdominal pain, fever and chills. Orchitis does not result in infertility for adolescents or adult men. Females could suffer from oophoritis and/or mastitis. [livestrong.com]
Swollen ovaries One in 20 females who get mumps after puberty experience swelling of the ovaries (oophoritis), which can cause: lower abdominal pain high temperature being sick The symptoms of oophoritis usually pass once the body has fought off the underlying [nhs.uk]
Urogenital
- Testicular Swelling
Orchitis (testicular swelling) happens in up to 50% of post-pubertal males, with oophritis (ovarian swelling) happening in only 5% of women. Orchitis often results in testicular atrophy but very rarely in sterility. [web.uconn.edu]
Symptoms of orchitis are testicular swelling and pain, usually involving one testis only. The testis or testes may shrink while healing, but sterility is rare. 4. [health24.com]
Mumps orchitis is characterized by marked testicular swelling and severe pain, accompanied by fever, nausea, and headache ( 121 – 123 ). The pain and swelling resolve within 5 to 7 days, although residual testicular tenderness can persist for weeks. [oncohemakey.com]
[…] becomes inflamed. [3] Testicular swelling has been documented as late as 6 weeks after parotid-gland swelling. [3] Decreased fertility is an uncommon consequence of testicular inflammation from mumps and infertility is rare. [3] Studies have reached [en.wikipedia.org]
Neurologic
- Agitation
People might receive other drugs such as steroids (to reduce inflammation), diuretics (to reduce pressure inside the head), and sedatives (to calm people if they are agitated and to help control seizures). [brainandspine.org.uk]
A year later, by then four years old, he was still suffering from seizures and he became increasingly lethargic, disoriented and agitated. His walking was increasingly uncoordinated and he began to lose his eyesight. [greenmedinfo.com]
Rabies encephalitis may be accompanied by hydrophobia and agitation. A vesicular rash may accompany varicella encephalitis; however, this may be absent. Therefore, a normal skin exam does not exclude this as a possible cause of encephalitis. [infectiousdiseaseadvisor.com]
Over the next few months, the child’s neurological condition deteriorated, with increasing seizures together with episodes of lethargy, disorientation, agitation, ataxic gait, visual loss and eventual hospitalisation. [link.springer.com]
- Clumsiness
When this infection is not very severe, the symptoms may be similar to those of other illnesses: Fever that is not very high Mild headache Low energy and a poor appetite Other symptoms include: Clumsiness, unsteady gait Confusion, disorientation Drowsiness [medlineplus.gov]
There may be stiffness of the limbs, slow movements, and clumsiness. The patient may also be drowsy and have a cough. [medicalnewstoday.com]
[…] drowsiness and confusion problems with memory speech problems changes in personality and uncharacteristic behaviour epilepsy (seizures) Other symptoms can include sensitivity to bright light and a lack of co-ordination (unsteadiness when walking or clumsiness [brainandspine.org.uk]
- Stupor
[…] recognize: Body stiffness Irritability and crying more often (these symptoms may get worse when the baby is picked up) Poor feeding Soft spot on the top of the head may bulge out more Vomiting Emergency symptoms: Loss of consciousness, poor responsiveness, stupor [medlineplus.gov]
There is a broad range of possible manifestations of altered mental status including personality changes, irritability lethargy, stupor, or coma. [infectiousdiseaseadvisor.com]
- Altered Mental Status
Symptoms then progress to fever, headache and altered mental status. [infectiousdiseaseadvisor.com]
- Myoclonus
Localized neurologic abnormalities, including cranial nerve palsies, seizures, hemiparesis, hypotonia or myoclonus, can be seen. A flaccid paralysis may be seen in WNV infection, mimicking or poliomyelitis. [infectiousdiseaseadvisor.com]
Workup
(See Workup.) Child with mumps. Even though the mumps virus, Rubulavirus, shares similar morphologic features to human parainfluenza viruses (known as hPIVs, as part of the Paramyxovirus genus), no cross-immunity between these viruses is known. [reference.medscape.com]
Treatment
Information about a therapy, service, product or treatment does not in any way endorse or support such therapy, service, product or treatment and is not intended to replace advice from your doctor or other registered health professional. [betterhealth.vic.gov.au]
Anti-infective agents Choice of treatment varies widely based on suspected or confirmed etiologic agent. Please see Table II for treatment options. Table II. Treatment options and adjunctive therapies for specific organisms. [infectiousdiseaseadvisor.com]
Treatment Treatment for encephalitis focuses on alleviating symptoms. [medicalnewstoday.com]
Treatment Treatment of the symptoms includes giving plenty of fluids. Paracetamol may be given for fever and pain. There is no specific antiviral treatment. [sahealth.sa.gov.au]
Treatment aims to ease symptoms until the body's immune system clears the virus: You do not usually need any treatment if your symptoms are mild. Paracetamol or ibuprofen can ease fever and pain. [patient.info]
Prognosis
Autism Mechanism Autism Classification Autism Screening Autism Prognosis [news-medical.net]
What should you tell the family about the patient's prognosis? The most predictive factor for prognosis in patients with encephalitis is the severity of disease. [infectiousdiseaseadvisor.com]
PROGNOSIS : Secondary bacterial infections of the respiratory and urinary tracts are major complications of acute encephalitis. [atsu.edu]
It is important for the clinician to establish whether an individual patient with mumps has clear evidence of encephalitis because that diagnosis has important implications for management and prognosis. [oncohemakey.com]
Etiology
Annual age-specific and age-standardized admission rates in each calendar year were analyzed in addition to trends in admission rates with a noted etiology with the introduction of PCR testing and measles-mumps-rubella (MMR) vaccines. [healio.com]
In this study we evaluated the incidence rates, seasonal variety and the main etiologic agents of AME, and identified factors that could be used to predict the etiologic agents. [journals.plos.org]
In the majority of cases, an etiologic agent is never identified. [infectiousdiseaseadvisor.com]
The etiology of the contacts’ illness was determined by viral culture, genomic sequencing, serology and epidemiological linking. [medscienceresearch.com]
Next, we investigated the ability of NGS to detect viral sequences in 18 pediatric patients with acute encephalitis/encephalopathy of unknown etiology. [nature.com]
Epidemiology
However, little is known about the epidemiology of all-cause childhood encephalitis in England because previous studies have either involved a specific etiological group — for example, viral encephalitis — or a predominantly adult population,” Mildred [healio.com]
Epidemiology The following is the clinical definition of mumps for the purpose of epidemiological surveillance: Any person with fever and at least one of the following: (1) sudden onset of unilateral or bilateral tender swelling of the parotid gland or [ecdc.europa.eu]
Describe the changing epidemiology of mumps. Monitor vaccine effectiveness. [who.int]
Tabs Content Clinical Overview Diagnosis Indications for Testing Atypical presentation of secondary complications in patients with apparent mumps Suspected outbreak – test patients for epidemiologic evidence Laboratory Testing Limited role for laboratory [arupconsult.com]
The IOM found no relevant epidemiologic studies of quality in the literature assessing an association between vaccination and MIBE [8]. [vaccinesafety.edu]
Pathophysiology
Provides in-depth coverage of CSF examination and analysis, CSF physiology and pathophysiology, approach to diagnosis, and future directions in CSF analysis. [books.google.com]
PATHOGENESIS AND PATHOPHYSIOLOGY Mumps is highly contagious, although some studies have suggested that it is less contagious than varicella or measles ( 68 ). [oncohemakey.com]
Prevention
Prevention Exclude the person with mumps from childcare, preschool, school and work for 5 days after the onset of swelling tissues and other objects soiled with nasal secretions should be disposed of appropriately mumps is best prevented by the measles [sahealth.sa.gov.au]
Emergencies & Disasters Find out about our Trauma system, volunteer, or see how we prepare and respond to emergencies Prevention & Healthy Living Quit tobacco, take care of your teeth, prevent HIV/AIDS, screen your breasts, get active. [healthy.arkansas.gov]
Epidemiology and Prevention of Vaccine-Preventable Diseases (9th ed.). Centers for Disease Control and prevention. Fulltext. [ dead link ] ^ Kanra G, Isik P, Kara A, Cengiz AB, Seçmeer G, Ceyhan M (2004). [en.wikipedia.org]
[…] vomiting medication to prevent seizures (anticonvulsant) medication to reduce fever, such as paracetamol fluids to prevent dehydration, but not too much as this can worsen cerebral oedema (swelling of the brain). [betterhealth.vic.gov.au]
Can Encephalitis Be Prevented? Encephalitis can't be prevented, but you can avoid the illnesses that may lead to it. Immunizations protect kids from many common childhood illnesses. So follow the immunization schedule recommended by your doctor. [kidshealth.org]