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Mumps Meningitis


Presentation

  • Thus, the differences in febrile presentation between the 2 groups seem to reflect differences in pathophysiology.[ncbi.nlm.nih.gov]
  • Patient had traveled to the New York City and New Jersey area a couple weeks before presentation.[academic.oup.com]
  • The purpose of the present study was to determine factors associated with mumps meningitis and to discuss the effect of vaccination on this disease.[semanticscholar.org]
  • The common presenting signs and symptoms seen in patients with mumps CNS infection are summarized in Table 16.1. The most frequently reported presentation is a triad of fever, vomiting, and headache.[oncohemakey.com]
  • A mumps viral infection is characterized by parotid gland swelling (31% to 65%), while other clinical presentations such as aseptic meningitis (1% to 10%) and encephalitis (0.1%) are rarer [ 3 ].[omicsonline.org]
Cervical Lymphadenopathy
  • Physical examination was remarkable for bilateral parotid gland enlargement, left submandibular and anterior cervical lymphadenopathy, and left testicular edema and erythema. Both testes had normal lie and positive cremasteric reflexes.[academic.oup.com]
Fever
  • You do not need any treatment if symptoms are mild Paracetamol or ibuprofen can be beneficial to ease fever and pain. Give children lots to drink, particularly if they have a fever.[brownlowhealth.co.uk]
  • Patients Table 2 Clinical features and cerebrospinal fluid profiles of mumps meningitis patients Findings Value Fever 18 (94.7) No. of days of fever 4 (1-6) Headache 16 (84.2) Nausea/vomiting 14 (73.7) Meningeal irritation signs 19 (100) Diagnosis of[ncbi.nlm.nih.gov]
  • Symptoms usually begin with a headache and fever, followed by a swelling of glands in the neck.[news.liverpool.ac.uk]
  • Mumps typically starts with a few days of fever, headache, muscle aches, tiredness, and loss of appetite, and is followed by swelling of salivary glands.[meningitis-angels.org]
  • However, intermittent vomiting associated with severe headache and high fever persisted.[omicsonline.org]
Stridor
  • He did not have poor dentition, dental abscesses, stridor, meningismus, trismus, tonsillar exudate, erythema, or edema. Initial laboratory results obtained in the ED were significant for an amylase level of 397.[academic.oup.com]
Dental Abscess
  • He did not have poor dentition, dental abscesses, stridor, meningismus, trismus, tonsillar exudate, erythema, or edema. Initial laboratory results obtained in the ED were significant for an amylase level of 397.[academic.oup.com]
Tonsillar Exudate
  • He did not have poor dentition, dental abscesses, stridor, meningismus, trismus, tonsillar exudate, erythema, or edema. Initial laboratory results obtained in the ED were significant for an amylase level of 397.[academic.oup.com]
Jaw Pain
  • CASE PRESENTATION A 26-year-old previously healthy male presented to the ED with a chief complaint of jaw pain for 2 days. He endorsed subjective fevers, chills, body aches, and left-sided jaw pain. The patient has no other prior medical history.[academic.oup.com]
Meningism
  • […] of aseptic meningitis in children.[scielo.br]
  • The patients were divided into 2 groups: those with meningitis (the meningitis group) and those without meningitis (the nonmeningitis group).[ncbi.nlm.nih.gov]
  • If you need a replacement, please ask at your Hall, at Brownlow Health, or via Meningitis Now. A free Meningitis ACWY Vaccination / Meningitis Booster is available for any unprotected individual under 25 years of age.[news.liverpool.ac.uk]
  • […] that Mimicked Tuberculous Meningitis.[omicsonline.org]
  • Parotiditis preceded meningitis in all our patients with an average of 8.3 days, while orchiepididymitis, when it occurred, appeared at the same time or after meningitis.[neurologia.com]
Neurologic Manifestation
  • Neurological manifestations and sequelae are generally more common in older patients 7, 8).[ncbi.nlm.nih.gov]

Workup

Staphylococcus Aureus
  • Without parotitis or hyperamylasemia, a differential diagnosis may include infection by Staphylococcus aureus, a gram-negative bacterium, and atypical mycobacteria [ 3 ], as cerebrospinal fluid (CSF) samples from affected individuals often contain a substantial[omicsonline.org]
Human Herpesvirus 6

Treatment

  • Currently, there is no specific treatment for mumps. Supportive care should be given as needed. If someone becomes very ill, they should seek medical attention.[meningitis-angels.org]
  • What is the treatment for mumps? There is no drug that kills the mumps virus. TFor most people, mumps improves over a week with no long-term problems. Treatment aims to ease symptoms until the body’s immune system clears the virus.[brownlowhealth.co.uk]
  • Although most people recover without treatment, in some cases it can cause complications such as inflammation of the testicles or ovaries, and in very rare cases, meningitis and deafness.[news.liverpool.ac.uk]
  • Conservative treatment was given with an intravenous drip infusion of 10% glycerin and empirical administration of acyclovir started on the day of admission (Day 1).[omicsonline.org]
  • If a doctor suspects meningitis, he or she may collect samples for testing by: Swabbing your nose or throat Obtaining a stool sample Taking some blood Drawing fluid from around your spinal cord Treatment In most cases, there is no specific treatment for[cdc.gov]

Prognosis

  • DOI: 10.1084/jem.34.6.537 Published December 1, 1921 Abstract It has been shown that an aseptic meningitis of 3 to 5 days duration and favorable prognosis can be induced in cats by intrathecal injection of sterile saliva filtrate from early cases of parotitis[jem.rupress.org]
  • It is important for the clinician to establish whether an individual patient with mumps has clear evidence of encephalitis because that diagnosis has important implications for management and prognosis.[oncohemakey.com]

Etiology

  • The etiologic viral diagnosis was based on serological tests and the isolation of virus from appropriate cell cultures which distinguished between attenuated and virulent mumps virus.[nature.com]
  • The patient was diagnosed as having aseptic meningitis with a probable viral etiology.[omicsonline.org]
  • An etiologic relationship between gestational mumps and endocardial fibroelastosis has been postulated ( 138 ).[oncohemakey.com]
  • Worldwide literature over the past 5 years has been very focused as to finding a potential etiology as to the resurgence of mumps.[academic.oup.com]

Epidemiology

  • Keywords Cerebrospinal fluid Epidemiology Orchiepididymitis Vaccination Classified in Infecciones You may be interested[neurologia.com]
  • An epidemiological study from prevaccine era 22) showed that the peak incidence of mumps meningitis was at the age of 7 years, while the highest rate of mumps meningitis was in those age 15 or more.[ncbi.nlm.nih.gov]
  • Epidemiology The following is the clinical definition of mumps for the purpose of epidemiological surveillance: Any person with fever and at least one of the following: (1) sudden onset of unilateral or bilateral tender swelling of the parotid gland or[ecdc.europa.eu]
  • Takeshima S, Yoshimoto T, Shiga Y, Kanaya Y, Neshige S, et al. (2015) Clinical, epidemiological and etiological studies of adult aseptic meningitis: Report of 13 cases with mumps meningitis. Rinsho Shinkei 55: 630-636.[omicsonline.org]
  • The true epidemiology of mumps in the United States is difficult to ascertain.[academic.oup.com]
Sex distribution
Age distribution

Pathophysiology

  • Thus, the differences in febrile presentation between the 2 groups seem to reflect differences in pathophysiology.[ncbi.nlm.nih.gov]
  • PATHOGENESIS AND PATHOPHYSIOLOGY Mumps is highly contagious, although some studies have suggested that it is less contagious than varicella or measles ( 68 ).[oncohemakey.com]

Prevention

  • We need to be more aggressive about prevention of mumps outbreak which bring on substantial socioeconomic loss.[koreamed.org]
  • Mumps prevention and the MMR Vaccination It is strongly advised that students who have not previously had TWO doses of the MMR (measles, mumps and rubella) vaccine contact their GP as soon as possible to arrange to have this free vaccination.[news.liverpool.ac.uk]
  • Mumps immunisation An effective vaccine to prevent mumps is available. It is part of the MMR vaccine. This is routinely offered to all children aged 12-15 months in the UK.[brownlowhealth.co.uk]
  • Our findings probably suggest that vaccination effectively prevents mumps meningitis, at least in children under a certain age or within a certain vaccination interval.[ncbi.nlm.nih.gov]
  • Prevention The best way to prevent mumps is to be vaccinated against the disease. Most people have immunity to mumps once they're fully vaccinated.[mayoclinic.org]

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