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Mycobacterial Infection

Mycobacterial Infectious Disease


Presentation

  • The clinical presentation, magnetic resonance imaging findings (including diffusion-weighted imaging), and pathologic findings of subcutaneous NTM infection are described and compared with those of tuberculosis and tumor presentations to provide a more[ncbi.nlm.nih.gov]
Gaucher Disease
  • Both patients had no clinical evidence of inherited Gaucher disease. The first case was a patient with AIDS and Mycobacterium avium intracellulare involving the lung, spleen, and bone marrow.[ncbi.nlm.nih.gov]
Pseudotumor
  • "Mycobacterium pseudotumor" is a nonneoplastic condition and should be distinguished from true KS as these 2 entities differ in their prognosis and treatment.[ncbi.nlm.nih.gov]
Leg Swelling
  • On subsequent clinic visits, the patient had decreased leg swelling and resolution of the papular lesions.[ncbi.nlm.nih.gov]
Abdominal Mass
  • Herein, we describe a 9-year-old girl and a 14-year-old boy with multiple large abdominal masses, fever, weight loss, and anemia.[ncbi.nlm.nih.gov]
Hypertension
  • Medical history included diabetes with peripheral neuropathy and renal insufficiency, hypertension, and right-sided heart failure felt to be due to obstructive sleep apnea.[ncbi.nlm.nih.gov]
Visual Impairment
  • Three children (27.3%) developed a visual impairment secondary to EMB, with delays of 4, 7 and 36 weeks.[ncbi.nlm.nih.gov]
Osteoporosis
  • Abstract Patients with Crohn's disease (CD) have higher risk for osteoporosis following decreased level of osteocalcin.[ncbi.nlm.nih.gov]
Skin Ulcer
  • M. ulcerans infection causes chronic skin ulcerations, usually on an arm or leg. Atypical mycobacteria infections can also occur without causing any symptoms. In such cases, a tuberculin skin test may be positive.[medical-dictionary.thefreedictionary.com]
Ecthyma
  • Ecthyma gangrenosum typically occurs in patients who are immunocompromised. It is most often associated with a Pseudomonas aeruginosa bacteremia but other pathogens can be found.[ncbi.nlm.nih.gov]
Facial Swelling
  • A four-year-old male presented with right-sided facial swelling near the angle of the mandible. Despite the presence of multiple dental carious lesions, the cervical lymphadenopathy did not appear to be of dental origin.[ncbi.nlm.nih.gov]
Renal Insufficiency
  • Medical history included diabetes with peripheral neuropathy and renal insufficiency, hypertension, and right-sided heart failure felt to be due to obstructive sleep apnea.[ncbi.nlm.nih.gov]

Workup

  • Interestingly, the diagnostic workup revealed that the patient had Lady Windermere syndrome which is one of features for Mycobacterium avium complex (MAC) pulmonary disease.[ncbi.nlm.nih.gov]
  • In cases of lung infection, a diagnostic workup will include a chest x ray and tests on discharges from the respiratory passages (sputum).[medical-dictionary.thefreedictionary.com]
Mycobacterium Kansasii
  • Mycobacterium kansasii should be treated with at least 3 drugs for 12–18 months. One of the drugs must be rifampicin, which is still the cornerstone of treatment for these infections.[dermnetnz.org]
  • The most common species of mycobacterium that cause such infections include: Mycobacterium avium-intracellulare Mycobacterium kansasii Mycobacterium marinum Mycobacterium ulcerans Mycobacterium chelonae Mycobacterium fortuitum Mycobacterium abscessus[dovemed.com]
  • Mycobacterium kansasii Infection with Mycobacterium kansasii (kan-ZAS-e-eye) causes a lung disease similar to tuberculosis, although not as severe.[humanillnesses.com]
  • These organisms include: Mycobacterium avium-intracellulare : 60% (on bronchial secretions) see: pulmonary MAIC infection Mycobacterium kansasii : 25% Mycobacterium fortuitum Mycobacteriumgordonae Mycobacterium szulgai Mycobacterium scrofulaceum / Mycobacterium[radiopaedia.org]
Mycobacterium Chelonae
  • We evaluated a patient with disseminated Mycobacterium tuberculosis and Mycobacterium chelonae infection, of which he died. He also developed autoimmune (type I) diabetes and primary hypothyroidism.[ncbi.nlm.nih.gov]
  • While the ulcerans and marinium forms of the bacteria have very specific areas of exposure, mycobacterium chelonae is prevalent in many water sources, including tap water.[ozarkderm.com]
  • chelonae : pulmonary Mycobacterium chelonae infection Mycobacterium simiae Mycobacterium abscesssus : pulmonary Mycobacterium abscessus infection 2 Risk factors The organisms have a predilection for individuals with pre-existing chronic obstructive pulmonary[radiopaedia.org]

Treatment

  • Our goal was to determine the clinical features of musculoskeletal NTM infection and to present the treatment outcomes.[ncbi.nlm.nih.gov]

Prognosis

  • Immune-reconstitution syndrome (IRS) occurred to 19 (79%) patients (8 paradoxical and 11 unmasking), and prognosis tended to be better in unmasking-IRS than the other patients (n 13) (p 0.078).[ncbi.nlm.nih.gov]
  • Treatment and prognosis Detailed guidelines on the management approach are available 12.[radiopaedia.org]
  • Prognosis The prognosis is good with proper medical and surgical treatment.[patient.info]

Etiology

  • A differential diagnosis of nondental etiologies of cervical lymphadenopathy in young children is described.[ncbi.nlm.nih.gov]
  • (Etiology) Atypical Mycobacterial Infections are caused by any species of non-tuberculous mycobacteria. Up to 13 distinct species of atypical mycobacteria are known to cause human infection.[dovemed.com]

Epidemiology

  • He recalled no antecedent trauma and denied any unusual epidemiologic exposure.[ncbi.nlm.nih.gov]
  • Section I presents basic concepts of epidemiology, pathophysiology, diagnosis, medical and surgical therapy, drug-resistant tuberculosis, vaccines, and tuberculosis in enclosed populations.[asmscience.org]
  • Introduction Nontuberculous mycobacterial infections Epidemiology demographics often found in marine workers location hand and wrist are involved in 50% of cases risk factors immunocompromised host Pathophysiology incubation average incubation period[orthobullets.com]
Sex distribution
Age distribution

Pathophysiology

  • Section I presents basic concepts of epidemiology, pathophysiology, diagnosis, medical and surgical therapy, drug-resistant tuberculosis, vaccines, and tuberculosis in enclosed populations.[asmscience.org]
  • Introduction Nontuberculous mycobacterial infections Epidemiology demographics often found in marine workers location hand and wrist are involved in 50% of cases risk factors immunocompromised host Pathophysiology incubation average incubation period[orthobullets.com]
  • Recent results support the use of zebrafish as a model for studying the pathophysiology of mycobacterial infection and for the development of novel interventions for tuberculosis (TB) control.[sabio-irec.com]
  • Effective prevention and therapy of MAC has the potential to contribute substantially to improved quality of life and duration of survival for HIV-infected persons. [12] Pathophysiology [ edit ] Mycobacterium avium complex is the most commonly found form[en.wikipedia.org]
  • Mycobacterium smegmatis may be either pigmented or nonpigmented. [3, 4, 5, 6] Pathophysiology Atypical mycobacteria are obligate aerobes that can be found in the environment in soil, water, vegetables, and even in domestic animals and dairy products.[emedicine.medscape.com]

Prevention

  • This study underlines the urgent need to intensify screening for mycobacteria coinfection with HIV and to prevent the spread of drug-resistant TB among HIV-infected patients.[ncbi.nlm.nih.gov]
  • You can prevent MAC by starting antiretroviral therapy (ART) early and not allow your CD4 count to get low.[webmd.com]
  • Can People Prevent Atypical Mycobacterial Infections? Because mycobacteria are common in the environment, these infections are difficult to prevent, especially in people with weakened immune systems.[encyclopedia.com]
  • The course developed a detailed understanding of immunopathogenic, clinical, therapeutic and preventive aspects of mycobacterial infections associated with the most common comorbidities.[escmid.org]

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