Presentation
We report a case in a 67-yr-old previously healthy woman who presented with a disseminated NTM infection in the uterine cervix. The primary presentation was general fatigue and body weight loss. [ncbi.nlm.nih.gov]
Immune System
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Generalized Lymphadenopathy
We described a patient with neutralizing autoantibodies to interferon-gamma (IFN-γ) and elevated levels of serum IgG4 presenting with generalized lymphadenopathy and reactive dermatosis. [ncbi.nlm.nih.gov]
Entire Body System
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Gaucher Disease
Both patients had no clinical evidence of inherited Gaucher disease. The first case was a patient with AIDS and Mycobacterium avium intracellulare involving the lung, spleen, and bone marrow. [ncbi.nlm.nih.gov]
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Pseudotumor
"Mycobacterium pseudotumor" is a nonneoplastic condition and should be distinguished from true KS as these 2 entities differ in their prognosis and treatment. [ncbi.nlm.nih.gov]
Gastrointestinal
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Abdominal Mass
Herein, we describe a 9-year-old girl and a 14-year-old boy with multiple large abdominal masses, fever, weight loss, and anemia. [ncbi.nlm.nih.gov]
Liver, Gall & Pancreas
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Hepatosplenomegaly
Thrombocytopenia, anemia, hepatosplenomegaly, and bone manifestations are the most typical signs of GD type 1 (GD1). [ncbi.nlm.nih.gov]
Eyes
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Visual Impairment
Three children (27.3%) developed a visual impairment secondary to EMB, with delays of 4, 7 and 36 weeks. [ncbi.nlm.nih.gov]
Skin
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Skin Ulcer
M. ulcerans infection causes chronic skin ulcerations, usually on an arm or leg. Atypical mycobacteria infections can also occur without causing any symptoms. In such cases, a tuberculin skin test may be positive. [medical-dictionary.thefreedictionary.com]
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Ecthyma
Ecthyma gangrenosum typically occurs in patients who are immunocompromised. It is most often associated with a Pseudomonas aeruginosa bacteremia but other pathogens can be found. [ncbi.nlm.nih.gov]
Face, Head & Neck
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Facial Swelling
A four-year-old male presented with right-sided facial swelling near the angle of the mandible. Despite the presence of multiple dental carious lesions, the cervical lymphadenopathy did not appear to be of dental origin. [ncbi.nlm.nih.gov]
Workup
Interestingly, the diagnostic workup revealed that the patient had Lady Windermere syndrome which is one of features for Mycobacterium avium complex (MAC) pulmonary disease. [ncbi.nlm.nih.gov]
In cases of lung infection, a diagnostic workup will include a chest x ray and tests on discharges from the respiratory passages (sputum). [medical-dictionary.thefreedictionary.com]
The diagnostic workup in May 2015 revealed an incidental 5-mm small pulmonary nodulus in the right upper lobe, which was observed to be metabolically active in PET–CT. [wwwnc.cdc.gov]
Microbiology
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Mycobacterium Chelonae
We evaluated a patient with disseminated Mycobacterium tuberculosis and Mycobacterium chelonae infection, of which he died. He also developed autoimmune (type I) diabetes and primary hypothyroidism. [ncbi.nlm.nih.gov]
While the ulcerans and marinium forms of the bacteria have very specific areas of exposure, mycobacterium chelonae is prevalent in many water sources, including tap water. [ozarkderm.com]
chelonae : pulmonary Mycobacterium chelonae infection Mycobacterium simiae Mycobacterium abscesssus : pulmonary Mycobacterium abscessus infection 2 Risk factors The organisms have a predilection for individuals with pre-existing chronic obstructive pulmonary [radiopaedia.org]
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Mycobacterium Kansasii
Mycobacterium kansasii should be treated with at least 3 drugs for 12–18 months. One of the drugs must be rifampicin, which is still the cornerstone of treatment for these infections. [dermnetnz.org]
These organisms include: Mycobacterium avium-intracellulare : 60% (on bronchial secretions) see: pulmonary MAIC infection Mycobacterium kansasii : 25% Mycobacterium fortuitum Mycobacteriumgordonae Mycobacterium szulgai Mycobacterium scrofulaceum / Mycobacterium [radiopaedia.org]
The most common species of mycobacterium that cause such infections include: Mycobacterium avium-intracellulare Mycobacterium kansasii Mycobacterium marinum Mycobacterium ulcerans Mycobacterium chelonae Mycobacterium fortuitum Mycobacterium abscessus [dovemed.com]
Mycobacterium kansasii Infection with Mycobacterium kansasii (kan-ZAS-e-eye) causes a lung disease similar to tuberculosis, although not as severe. [humanillnesses.com]
Treatment
Our goal was to determine the clinical features of musculoskeletal NTM infection and to present the treatment outcomes. [ncbi.nlm.nih.gov]
Prognosis
Immune-reconstitution syndrome (IRS) occurred to 19 (79%) patients (8 paradoxical and 11 unmasking), and prognosis tended to be better in unmasking-IRS than the other patients (n 13) (p 0.078). [ncbi.nlm.nih.gov]
Treatment and prognosis Detailed guidelines on the management approach are available 12. [radiopaedia.org]
Prognosis The prognosis is good with proper medical and surgical treatment. [patient.info]
Etiology
A differential diagnosis of nondental etiologies of cervical lymphadenopathy in young children is described. [ncbi.nlm.nih.gov]
Precise identification of etiologic NTM organisms could help predict treatment outcomes in patients with NTM-LD due to mixed infections. [aac.asm.org]
(Etiology) Atypical Mycobacterial Infections are caused by any species of non-tuberculous mycobacteria. Up to 13 distinct species of atypical mycobacteria are known to cause human infection. [dovemed.com]
Epidemiology
He recalled no antecedent trauma and denied any unusual epidemiologic exposure. [ncbi.nlm.nih.gov]
Section I presents basic concepts of epidemiology, pathophysiology, diagnosis, medical and surgical therapy, drug-resistant tuberculosis, vaccines, and tuberculosis in enclosed populations. [asmscience.org]
Introduction Nontuberculous mycobacterial infections Epidemiology demographics often found in marine workers location hand and wrist are involved in 50% of cases risk factors immunocompromised host Pathophysiology incubation average incubation period [orthobullets.com]
Pathophysiology
Section I presents basic concepts of epidemiology, pathophysiology, diagnosis, medical and surgical therapy, drug-resistant tuberculosis, vaccines, and tuberculosis in enclosed populations. [asmscience.org]
Introduction Nontuberculous mycobacterial infections Epidemiology demographics often found in marine workers location hand and wrist are involved in 50% of cases risk factors immunocompromised host Pathophysiology incubation average incubation period [orthobullets.com]
Recent results support the use of zebrafish as a model for studying the pathophysiology of mycobacterial infection and for the development of novel interventions for tuberculosis (TB) control. [sabio-irec.com]
Effective prevention and therapy of MAC has the potential to contribute substantially to improved quality of life and duration of survival for HIV-infected persons. [12] Pathophysiology [ edit ] Mycobacterium avium complex is the most commonly found form [en.wikipedia.org]
Mycobacterium smegmatis may be either pigmented or nonpigmented. [3, 4, 5, 6] Pathophysiology Atypical mycobacteria are obligate aerobes that can be found in the environment in soil, water, vegetables, and even in domestic animals and dairy products. [emedicine.medscape.com]
Prevention
This study underlines the urgent need to intensify screening for mycobacteria coinfection with HIV and to prevent the spread of drug-resistant TB among HIV-infected patients. [ncbi.nlm.nih.gov]
You can prevent MAC by starting antiretroviral therapy (ART) early and not allow your CD4 count to get low. [webmd.com]
The course developed a detailed understanding of immunopathogenic, clinical, therapeutic and preventive aspects of mycobacterial infections associated with the most common comorbidities. [escmid.org]
Prevention People with HIV infection can prevent or delay the onset of MAC by taking disease-preventing drugs such as rifabutin. [medical-dictionary.thefreedictionary.com]