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Mycobacterium Fortuitum


Presentation

  • Abstract Orbital infection with nontuberculous mycobacteria is rare and usually presents as an inflammatory process.[ncbi.nlm.nih.gov]
  • Wound discharge, fever, and pain at generator site were the most common presenting features. At presentation they had a median duration of symptoms of 34 days. Concomitant bacteremia was present in half of the cases.[ncbi.nlm.nih.gov]
  • Patients usally present with vague complaints of abdominal pain, vomitting, diarrhea, weight loss and change in peritoneal transport characte-ristics.[ncbi.nlm.nih.gov]
  • BACKGROUND: Prosthetic valve endocarditis presents unique challenges for both diagnosis and treatment. A potential role of biofilm has been hypothesized in the pathogenesis of these infections.[ncbi.nlm.nih.gov]
  • LESSONS: Although the M.fortuitum infection presenting as septicemia is rare, a high suspicion of M.fortuitum is required, particularly in the immunosuppressive patients. Timely and adequate treatment is necessary.[ncbi.nlm.nih.gov]
Fever
  • No episodes of fever occurred during the follow-up to date. LESSONS: RGM infections remain a challenging issue for TIVAPs.[ncbi.nlm.nih.gov]
  • Abstract A 14-year-old male child presented with high grade intermittent fever with altered sensorium since 5-6 days and generalised seizures. On examination neck stiffness noticed with normal haemogram and chest X-ray.[ncbi.nlm.nih.gov]
  • Wound discharge, fever, and pain at generator site were the most common presenting features. At presentation they had a median duration of symptoms of 34 days. Concomitant bacteremia was present in half of the cases.[ncbi.nlm.nih.gov]
  • After initiation, of treatment with amikacin to which the strain was sensitive and clarithromycin and removal of the central line the patient's fever defervesced and repeat blood cultures were negative.[ncbi.nlm.nih.gov]
  • She gradually developed a high-grade fever with a growing infiltrative shadow on chest CT and an enlarging bilateral cervical mass.[ncbi.nlm.nih.gov]
Soft Tissue Swelling
  • We report a case of localized recurrent soft tissue swelling of the foot by Mycobacterium fortuitum in a healthy adult male. The case is being reported for its uncommon clinical presentation and the associated etiological agent.[ncbi.nlm.nih.gov]
Varicella-Zoster Virus Infection
  • Here, we report a case of Mycobacterium fortuitum infection in a previously healthy 9-year-old patient who developed cervical lymphadenitis evolving to a suppurative ulcer associated with a varicella-zoster virus infection.[ncbi.nlm.nih.gov]
High Fever
  • PATIENT CONCERNS: A 48-year-old immunocompromised male with extranodal NK/T-cell lymphoma, nasal type was admitted to the hospital because of high fever for 10 days.[ncbi.nlm.nih.gov]
Pleural Effusion
  • To our knowledge, this is the first reported case of haemorrhagic pleural effusion in an immunocompetent patient without underlying diseases.[ncbi.nlm.nih.gov]
  • Clinically, he had a right pleural effusion and gross hepatomegaly. The patient was lymphopaenic and had deranged liver function test. Repeat paired blood cultures were positive for M. fortuitum.[ncbi.nlm.nih.gov]
  • Previously rare, cases of peritonitis in dialysis patients, catheter-associated sepsis, pulmonary infection, and pleural effusion, including empyema, are now on the increase ( 2 , 6 , 7 ).[jcm.asm.org]
Respiratory Distress
  • He was febrile, toxic-looking and was in respiratory distress. Clinically, he had a right pleural effusion and gross hepatomegaly. The patient was lymphopaenic and had deranged liver function test.[ncbi.nlm.nih.gov]
  • His postnatal course was complicated by respiratory distress syndrome, requiring intubation, ventilation and 1 dose of surfactant.[journals.lww.com]
Hepatomegaly
  • Clinically, he had a right pleural effusion and gross hepatomegaly. The patient was lymphopaenic and had deranged liver function test. Repeat paired blood cultures were positive for M. fortuitum.[ncbi.nlm.nih.gov]
Diplopia
  • We report a case of a 34-year-old male hospital worker with a positive purified protein derivative skin test who had Mycobacterium fortuitum infection that presented as an orbital mass causing diplopia.[ncbi.nlm.nih.gov]
Skin Ulcer
  • […] pulmonary disease: the commonest atypical mycobacterial infection caused by M. kansasii or M. avium-intracellulare commonest in white males over 45 years with pre-existing lung disease lymphadenitis: a disease of childhood caused by M. avium-intracellulare skin[gpnotebook.co.uk]
Neck Swelling
  • Abstract A 31-year-old African man with a blameless medical history presented with an enlarging neck swelling of 6 months duration. He was systemically well with normal heamatobiochemistry.[ncbi.nlm.nih.gov]

Workup

Right Pleural Effusion
  • Clinically, he had a right pleural effusion and gross hepatomegaly. The patient was lymphopaenic and had deranged liver function test. Repeat paired blood cultures were positive for M. fortuitum.[ncbi.nlm.nih.gov]
Mycobacterium Chelonae
  • The rapidly growing nontubercular mycobacteria, such as Mycobacterium fortuitum and Mycobacterium chelonae, are of increasing clinical importance because infections due to these organisms are often hospital acquired.[ncbi.nlm.nih.gov]
  • Among them, the rapidly growing organisms such as Mycobacterium chelonae, Mycobacterium fortuitum and Mycobacterium abscessus are widespread in nature and in hospital environments [16].[medical-dictionary.thefreedictionary.com]
  • Mycobacterium chelonae keratitis after laser in situ keratomileusis successfully treated with medical therapy and flap removal. Am J Ophthalmol 2000;129:382-84. 5. Garg P, Bansal AK, Sharma S, Vemuganti GK.[ijo.in]
  • Swenson JM, Wallace RJ Jr, Silcox VA, Thornsberry C: Antimicrobial susceptibility of five subgroups of Mycobacterium fortuitum and Mycobacterium chelonae. Antimicrob Agents Chemother 1985;28:807–811.[karger.com]
Pleural Effusion
  • To our knowledge, this is the first reported case of haemorrhagic pleural effusion in an immunocompetent patient without underlying diseases.[ncbi.nlm.nih.gov]
  • Clinically, he had a right pleural effusion and gross hepatomegaly. The patient was lymphopaenic and had deranged liver function test. Repeat paired blood cultures were positive for M. fortuitum.[ncbi.nlm.nih.gov]
  • Previously rare, cases of peritonitis in dialysis patients, catheter-associated sepsis, pulmonary infection, and pleural effusion, including empyema, are now on the increase ( 2 , 6 , 7 ).[jcm.asm.org]

Treatment

  • Timely and adequate treatment is necessary.[ncbi.nlm.nih.gov]
  • Treatment was complicated by delayed diagnosis, requirement for special investigations, treatment with multiple antibiotics, and conversion to haemodialysis following removal of her Tenckhoff catheter.[ncbi.nlm.nih.gov]
  • Herein, we report one case of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with antibiotics for the treatment of multiple skin abscesses in the hands caused by M. fortuitum.[ncbi.nlm.nih.gov]
  • The lesions developed at the injection sites of mesotherapy treatment. M. fortuitum was cultured from a biopsy specimen and purulent fluid drained from lesions.[ncbi.nlm.nih.gov]
  • CONCLUSION: To our knowledge, this is the first case report of parotitis caused by M. fortuitum and its successful medical treatment.[ncbi.nlm.nih.gov]

Prognosis

  • Clinical observations, with special reference to factors influencing prognosis, Rev. Infect.[books.google.ro]

Etiology

  • The case is being reported for its uncommon clinical presentation and the associated etiological agent. The patient recovered completely following therapy with amikacin and clarithromycin.[ncbi.nlm.nih.gov]
  • CONCLUSIONS: This case demonstrates the importance of suspecting mycobacterial etiology in patients with nodules and abscesses in the areas of mesotherapy treatment.[ncbi.nlm.nih.gov]
  • This microorganism is an uncommon etiological agent of lung lesions; among lung lesions caused by M. fortuitum, thoracic empyema is particularly rare.[ncbi.nlm.nih.gov]
  • These organisms are more often identified when the clinician suspects a more unusual etiology of infection because of poor response to standard antimicrobial therapy.[scholarworks.wmich.edu]
  • ., An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis, Science, 244, 362, 1989. ‎[books.google.de]

Epidemiology

  • Herein is reported a case of native valve endocarditis caused by M. fortuitum; the epidemiology and management of this rare cause of culture-negative endocarditis is discussed.[ncbi.nlm.nih.gov]
  • DESIGN: Descriptive epidemiology. SETTING: Private practice. PATIENTS OR OTHER PARTICIPANTS: Case subjects were customers of a single beauty salon who were treated with mesotherapy injections.[ncbi.nlm.nih.gov]
  • Copyright 2015 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. KEYWORDS: Breast; Mycobacterium fortuitum; Surgical wound infection; Water supply[ncbi.nlm.nih.gov]
  • Epidemiology of nontubercuious mycobacterial diseases in the United States. Am review of Respir Dis. 1987;135:1007-14 8. DalovisioJR Panky GA, Wallace RJ, Jones DB.[ijmm.org]
  • Patient Population: Prevalence and Epidemiology Knee // Shoulder & Elbow // Hip // Spine // Foot & Ankle // Hand & Wrist Fragility Fractures: Diagnosis and Treatment Shoulder & Elbow The Characteristics of Surgeons Performing Total Shoulder Arthroplasty[amjorthopedics.com]
Sex distribution
Age distribution

Prevention

  • Explorative laparoscopy prior to catheter reinsertion revealed multiple adhesions within the peritoneal cavity, preventing adequate catheter function.[ncbi.nlm.nih.gov]
  • Author information 1 Department of Infectious Diseases, Microbiology and Preventive Medicine, University Hospital Virgen del Rocio, Sevilla, Spain. 2 Paediatric Infectious Diseases and Immunopathology Unit, University -Hospital Virgen del Rocio, Sevilla[ncbi.nlm.nih.gov]
  • The most recent estimates come from voluntary reports tracked by the Centers for Disease Control and Prevention (CDC).[emedicine.medscape.com]
  • Biosafety level 2 The 2007 guideline “Official American Thoracic Society (ATS) and Infectious Diseases Society of America (IDSA) statement: diagnosis, treatment, and prevention of non-tuberculosis mycobacterial diseases”, notes that M. fortuitum isolates[en.wikipedia.org]

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