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Mycobacterium Lepraemurium


Presentation

  • The present work suggests that M. leprae has a special position in mycobacterial phylogeny.[ncbi.nlm.nih.gov]
  • ISSN: 1098-612X Subject: cats , Mycobacterium lepraemurium , disease diagnosis , medical treatment , case studies , leprosy , Greece Abstract: A 2-year-old, 4 kg, healthy, domestic shorthair female cat presented with ulcerated subcutaneous nodules on[pubag.nal.usda.gov]
  • J Immunol June 1, 1988, 140 (11) 3956-3961; Abstract Mycobacterium lepraemurium failed to stimulate a normal respiratory burst when presented to mouse peritoneal or bone marrow macrophages.[jimmunol.org]
  • GPLs are present on the outermost layer of the cell wall, and therefore, they play an important role in sliding motility, biofilm formation, and pathogenesis ( 24 ).[mbio.asm.org]
  • (to the extent they do not conflict with the terms of this Agreement), you may use the images on the Site solely for (a) editorial use by press and/or industry analysts, (b) in connection with a normal, peer-reviewed, scientific publication, book or presentation[pacb.com]
Weakness
  • C57BL mice that had lost their delayed-type hypersensitivity to MLM during the course of a disseminated infection showed a fairly strong antibody response to three antigens and a weak response to three others.[ncbi.nlm.nih.gov]
  • Macrophages primed in vitro by exposure to Escherichia coli LPS for 24 h did show a moderate O2- response when stimulated by M. lepraemurium, but macrophages primed by exposure to IFN-gamma muramyl dipeptide, or M. lepraemurium showed a weak response[jimmunol.org]
Fishing
  • Etymology: N.L. gen. masc. n. shottsii, of Shotts, named after Emmett Shotts, an American fish bacteriologist.[bacterio.net]
Ulcer
  • Skin mycobacteriosis was diagnosed after detection of numerous acid-fast bacilli in Ziehl Neelsen-stained smears from the ulcers.[pubag.nal.usda.gov]
  • Disease occurs mainly in the skin and lymph nodes, causing induration, alopecia and eventual ulceration. Nodular lesions, involving subcutaneous tissues, may be solitary or multiple and usually confined to the head region or the limbs.[en.wikipedia.org]
  • M. lepraemurium is one of the causative agents of leprosy in cats and causes granulomatous skin lesions that often involve ulceration ( 5 ). In humans, leprosy is primarily caused by Mycobacterium leprae and Mycobacterium lepromatosis .[mbio.asm.org]
  • Etymology: L. part. adj. ulcerans, making sore, causing to ulcerate. Approved Lists reference: SKERMAN (V.B.D.), McGOWAN (V.) and SNEATH (P.H.A.) (editors): Approved Lists of Bacterial Names. Int. J. Syst.[bacterio.net]
Skin Lesion
  • M. lepraemurium is one of the causative agents of leprosy in cats and causes granulomatous skin lesions that often involve ulceration ( 5 ). In humans, leprosy is primarily caused by Mycobacterium leprae and Mycobacterium lepromatosis .[mbio.asm.org]
  • .): A strain of Mycobacterium isolated from skin lesions of a cold blooded animal, Xenopus laevus, and its relation to atypical acid-fast bacilli occurring in man. Journal of Hygiene, 1959, 57, 57-67.[bacterio.net]
Alopecia
  • Disease occurs mainly in the skin and lymph nodes, causing induration, alopecia and eventual ulceration. Nodular lesions, involving subcutaneous tissues, may be solitary or multiple and usually confined to the head region or the limbs.[en.wikipedia.org]
Suggestibility
  • The present work suggests that M. leprae has a special position in mycobacterial phylogeny.[ncbi.nlm.nih.gov]
  • In M. lepraemurium , gene MLM_2357 (homologous to MAV_2928 ) and MLM_1265 (homologous to MAV_1346 ) are functional, suggesting that they may help its survival in macrophages.[mbio.asm.org]
  • Due to the similar clinical manifestations of human and murine leprosy and the difficulty of growing both bacilli axenically, Mycobacterium leprae and M. lepraemurium were once thought to be closely related, although it was later suggested that M. lepraemurium[mbio.asm.org]
  • The results suggest that M. lepraemurium is taken into macrophages by a mechanism that bypasses the FcR and other receptors that are capable of triggering the production of O2-.[jimmunol.org]
  • These authors suggest, but not formally propose, the designation " Mycobacterium avium subsp. hominissuis " for the isolates from humans and pigs.[bacterio.net]

Treatment

  • Harvard APA Vancouver Author BibTeX @article{1d7beec1859c4dafa63638d085773be1, title "In vitro sensivity of Mycobacterium lepraemurium for antimycobacterial drugs", keywords "B780-tropical-medicine, Mycobacterium lepraemurium, Bacteriology, Laboratory, Treatment[pure.itg.be]
  • Surgical excision of the lesions is the preferred treatment. Only the densely and uniformly stained forms appear to be infectious for animals, in contrast to the degenerate unevenly stained forms.[en.wikipedia.org]
  • ISSN: 1098-612X Subject: cats , Mycobacterium lepraemurium , disease diagnosis , medical treatment , case studies , leprosy , Greece Abstract: A 2-year-old, 4 kg, healthy, domestic shorthair female cat presented with ulcerated subcutaneous nodules on[pubag.nal.usda.gov]
  • ID with epilepsy in children is a chronic and devastating disorder that has poor treatment options and disease outcomes.[thermh.org.au]

Etiology

  • Biológicas, Instituto Politécnico Nacional, Carpio y Plan de Ayala, Colonia Santo Tomás, 11340 México México Source of Support: None, Conflict of Interest: None DOI: 10.4103/ijmy.ijmy_24_16 Objective/Background: Mycobacterium lepraemurium (MLM), the etiologic[ijmyco.org]
  • Determination of the etiology of presumptive feline leprosy by 16S rRNA gene analysis, Journal of Clinical Microbiology, 35, 1997, 2464 – 2471.[doi.org]
  • .): Etiology of farcy in African bovines: nomenclature of the causal organisms Mycobacterium farcinogenes Chamoiseau and Mycobacterium senegalense (Chamoiseau) comb. nov. International Journal of Systematic Bacteriology, 1979, 29, 407-410.[bacterio.net]

Prevention

  • There they inhibit phagosome maturation by preventing acidification to a pH below 6.4, and thus, prevent fusion with the extremely acidic lysosome.[mbio.asm.org]

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