Taking into account the small numbers in the present report, the specificity would be 100%. [erj.ersjournals.com]

Intraocular tuberculosis is uncommon and has various clinical presentations. Lack of specific clinical clues can make the diagnosis challenging. [ncbi.nlm.nih.gov]

• Burkina Faso

  West Africa is dominated by the presence of the Cameroon lineage, present in Burkina Faso, Ghana, Nigeria and Cameroon. [journals.plos.org]

• Purulent Sputum

  Case C was a 66-yr-old male who produced purulent sputum for a few months. There were no complaints of fever, haemoptysis or weight loss. [erj.ersjournals.com]

However, such a highly sensitive tool results in low specificity, with 90.5% of the patients without TB receiving respiratory isolation and workup for TB, which may be infeasible. [erj.ersjournals.com]

(See Workup.) The usual treatment regimen for TB cases from fully susceptible M tuberculosis isolates consists of 6 months of multidrug therapy. [emedicine.medscape.com]

• Plasmodium Falciparum

  Joy DA, Feng X, Mu J, Furuya T, Chotivanich K, et al. (2003) Early origin and recent expansion of Plasmodium falciparum. Science 300: 318–321. View Article Google Scholar 29. [doi.org]

  Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite. Proc Natl Acad Sci U S A. 2012;109:13052–7. [genomebiology.biomedcentral.com]

Treatment: With appropriate antibiotic treatment, TB can be cured in most people. Treatment usually combines several different antibiotic drugs that are given for at least 6 months and up to 12 months. [en.vircell.com]

(5102295715)-ar.png 504x634; 317 KB Extensively Drug-Resistant Tuberculosis (XDR TB) Diminishing Options for Treatment (5102295715).jpg 504x634; 161 KB First-Line Treatment of Tuberculosis (TB) for Drug-Sensitive TB (5102307249).jpg 721x573; 212 KB Fluh2 [commons.wikimedia.org]

Abstract Although tuberculosis treatment is dependent on drug-susceptibility testing (DST) and molecular drug-resistance detection, treatment failure and relapse remain a challenge. [ncbi.nlm.nih.gov]

Its prognosis is poor and optimal therapy has not been determined. Tuberculous meningitis has a high mortality in those also infected with HIV, especially in the developing world, and better therapies are urgently needed. [ncbi.nlm.nih.gov]

Treatment and prognosis Treatment consists of combination antibiotic therapy for at least six months. The agents isoniazid, rifampin, ethambutol, and pyrazinamide are considered first-line antituberculosis agents. [radiopaedia.org]

[…] usually in the lungs) to other organs and tissues via the bloodstream Skin lesions are small (millet-sized) red spots that develop into ulcers and abscesses More likely in immunocompromised patients, eg HIV, AIDS, cancer The patient is generally sick Prognosis [dermnetnz.org]

What should you tell the family about the patient’s prognosis? Outcome is determined by the organ involved and the stage at which treatment is initiated. [infectiousdiseaseadvisor.com]

Potential etiological factors include: tumors, allergy, parasitic infections, trauma. [ncbi.nlm.nih.gov]

Demonstrating mycobacterial antigens is useful in establishing mycobacterial etiology and can be used as an alternative method to the conventional Ziehl-Neelsen method. [biocare.net]

All isolates were previously typed by spoligotyping and IS6110-RFLP, and for each strain epidemiological records were available ( 14, 24 ). Forty-four isolates with no known epidemiological links were chosen within 12 groups (Table 2 ). [doi.org]

The worldwide threat of tuberculosis to human health emphasizes the need to develop novel approaches to a global epidemiological surveillance. [ncbi.nlm.nih.gov]

Thus, new insights into the pathophysiological features of the Mtb complex strains are required for development of novel vaccines and for control of MDR/XDR Mtb infection, eventually leading to refinement of treatment regimens and the health care system [ncbi.nlm.nih.gov]

Pathophysiology M. tuberculosis is transmitted airborne, i.e. by droplet infection. M. tuberculosis is a facultative intracellular parasite. When inhaled, the organism is taken up by alveolar macrophages. [radiopaedia.org]

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Each year, Mycobacterium tuberculosis accounts for approximately 1.4 million deaths and is responsible for 9 million newly diagnosed [mayomedicallaboratories.com]

Pathophysiology Infection with M tuberculosis results most commonly through exposure of the lungs or mucous membranes to infected aerosols. [emedicine.medscape.com]

[…] for Disease Control and Prevention, Beijing, China. 2 Beijing Center for Diseases Prevention and Control, Beijing 100013, China. 3 State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control [ncbi.nlm.nih.gov]

Its cell wall prevents the fusion of the phagosome with a lysosome. Specifically, M. tuberculosis blocks the bridging molecule, early endosomal autoantigen 1 (EEA1); however, this blockade does not prevent fusion of vesicles filled with nutrients. [microbiologyinpictures.com]

[…] and Prevention) - PDF Tuberculosis: General Information (Centers for Disease Control and Prevention) - PDF [medlineplus.gov]