Results: A 23 year old woman with a history of migraines presented with one day of headache, nausea, vomiting, fever, and vertical diplopia in the context of an upper respiratory tract infection. [neurology.org]

HDM extracts are made from natural animal material which opens up the possibility for different kinds of bacteria to be present in them from the mite of origin. [citeqbiologics.com]

A 20-year-old man presented with a 1-month history of blurry vision. Prior to presentation, he completed a 1-week course of oral levofloxacin for community-acquired pneumonia. His visual acuity was 20/25 in the right eye and 20/30 in the left eye. [jamanetwork.com]

• Malaise

  Infection occurs in 3 to 4 year cycles in temperate climates and chiefly affects children and young adults, causing an atypical pneumonia characterised by an influenza-like respiratory illness of gradual onset with headache, malaise, fever and cough [gpnotebook.co.uk]

  Tabs Content Clinical Overview Diagnosis Indications for Testing Mild illness consisting of upper or lower respiratory illness with gradual onset of Malaise Fever Headache Sore throat Persistent cough Atypical pneumonia appearance on chest x-ray (patchy [arupconsult.com]

  The clinical symptoms associated with M. pneumoniae infection are diverse, but the disease is characterised by the onset of fever, headache, general malaise, pharyngitis, tracheobronchitis and a persistent cough that increases in severity. [thenativeantigencompany.com]

  The symptoms reported by patients varies: fever, malaise, headache, coughing sore throat, chills, ear pain, diarrhea, nausea / vomiting, chest pain and skin rashes with fever, cough, malaise and headache. [lyme-basics.com]

  Typical symptoms include fever, cough, bronchitis, sore throat, headache, and malaise. A common result of Mycoplasma infection is pneumonia (sometimes called "walking pneumonia" because it is usually mild and rarely requires hospitalization). [www1.nyc.gov]

• Chills

  Symptoms develop over 1 to 3 weeks and include: fever dry cough headache chills heavy sweating scratchy sore throat sore trachea (the large airway between the mouth and the lungs) sore chest malaise (feeling of being unwell). [sahealth.sa.gov.au]

  Other symptoms are like those of other respiratory infections: Fever Headaches Chills Sweating Chest pain Ear pain Sore throat What other tests might I have along with this test? You may also have a chest X-ray to diagnose pneumonia. [urmc.rochester.edu]

  […] myalgias, sore throat, headache (retro-orbital), ear pain, and fever Advanced infection Dry, nonproductive cough occurs 3-5 days after onset of initial nonspecific symptoms Cough may produce mucopurulent sputum later in illness May be accompanied by chills [arupconsult.com]

  Common symptoms include any of the following: Chest pain Chills Cough, usually dry and not bloody Excessive sweating Fever (may be high) Headache Sore throat Less common symptoms include: Ear pain Eye pain or soreness Muscle aches and joint stiffness [ufhealth.org]

• High Fever

  The most common symptoms are Bronchitis Upper respiratory tract infections, including sore throats and, at times, ear infections Children with this infection may also have a high fever, long-lasting weakness, and in some cases, headaches and a rash. [healthychildren.org]

  Patients usually do not have severe shortness of breath, high fever, and a productive cough with MP. They more commonly have low-grade fever, dry cough, mild shortness of breath especially with exertion, and fatigue. [healthline.com]

• Lymphadenopathy

  Other reported plain film findings include bilateral lesions, pleural effusion (uncommon - in ~25% of cases) and hilar lymphadenopathy. [radiopaedia.org]

  Narita M, Yamada S, Nakayama T, Sawada H, Nakajima M, et al. (2001) Two cases of lymphadenopathy with liver dysfunction due to Mycoplasma pneumoniae infection with mycoplasmal bacteraemia without pneumonia. J Infect 42: 154–156. [journals.plos.org]

  Cutaneous T-cell lymphoma can cause harmless swelling, known as ´reactive´ or ´dermopathic´ lymphadenopathy, or result in malignant growth in the lymph nodes. [dermnetnz.org]

  It mostly presents with erythema, together with lymphadenopathy and blood involvement with Sézary cells. [dovepress.com]

  On examination, patients present with a sore throat that rarely has exudates or lymphadenopathy. Upon auscultation, the patient may have variable findings dependent on the extent of infection. [ncbi.nlm.nih.gov]

• Rigor

  Symptoms may include the following: Generalized aches and pains Fever (usually ≤ 102°F) Cough - Usually nonproductive Sore throat (nonexudative pharyngitis) Headache/myalgias Chills but not rigors Nasal congestion with coryza Earache General malaise In [medscape.com]

  Therefore, we individually assessed the following domains of potential bias: source population, method of participant selection, rigor of the exposure measurement, rigor of the outcome measure, control for confounding, and whether the reported data were [doi.org]

  The chronic, flu-like nature of the mycoplasma-caused disease, contrasting with the abrupt, rigorous onset of most bacterial pneumonias, has led to its nickname "walking pneumonia". [globin.bx.psu.edu]

• Dry Cough

  Patients usually do not have severe shortness of breath, high fever, and a productive cough with MP. They more commonly have low-grade fever, dry cough, mild shortness of breath especially with exertion, and fatigue. [healthline.com]

• Productive Cough

  Most cases of M. pneumoniae infection are mild and self-limited, causing nonspecific symptoms such as bronchitis, a runny nose, and a non-productive cough that may persist for several weeks. [labtestsonline.org.uk]

  Patients usually do not have severe shortness of breath, high fever, and a productive cough with MP. They more commonly have low-grade fever, dry cough, mild shortness of breath especially with exertion, and fatigue. [healthline.com]

• Chest Pain

  and fever Advanced infection Dry, nonproductive cough occurs 3-5 days after onset of initial nonspecific symptoms Cough may produce mucopurulent sputum later in illness May be accompanied by chills, chest pain, shortness of breath, nausea, vomiting, [arupconsult.com]

  Other symptoms are like those of other respiratory infections: Fever Headaches Chills Sweating Chest pain Ear pain Sore throat What other tests might I have along with this test? You may also have a chest X-ray to diagnose pneumonia. [urmc.rochester.edu]

  Common symptoms include any of the following: Chest pain Chills Cough, usually dry and not bloody Excessive sweating Fever (may be high) Headache Sore throat Less common symptoms include: Ear pain Eye pain or soreness Muscle aches and joint stiffness [ufhealth.org]

  These can include: difficulty breathing rapid, shallow breathing wheezing chest pain that feels worse when a person breathes or coughs raised heart rate sweating and shivering a loss of appetites malaise, or a general feeling of being unwell A person [medicalnewstoday.com]

  The symptoms reported by patients varies: fever, malaise, headache, coughing sore throat, chills, ear pain, diarrhea, nausea / vomiting, chest pain and skin rashes with fever, cough, malaise and headache. [lyme-basics.com]

• Urticaria

  Association of acute urticaria with Mycoplasma pneumoniae infection in hospitalized children. Ann Allergy Asthma Immunol 2009; 103: 134–9. [dermnetnz.org]

  It has been associated with other diseases, such as pleuropericarditis, pleuritis, reactive arthritis, predominantly cutaneous vasculitis, cold urticaria, lymphocytic meningitis, disseminated encephalomyelitis, Guillain–Barré syndrome, Adie syndrome and [analesdepediatria.org]

  Skin rash, urticaria and pityriasis rosea. Erythema multiforme. An infectious cause of Stevens-Johnson syndrome. In immunocompromised skin conditions are worse. [lyme-basics.com]

  Mycoplasma pneumoniae infection-induced erythema nodosum, anaphylactoid purpura, and acute urticaria in 3 people in a single family. J Am Acad Dermatol. 2007 Aug. 57(2 Suppl):S33-5. Fearon D, Hesketh EL, Mitchell AE, Grimwood K. [emedicine.medscape.com]

• Eruptions

  Diagnosis of M. pneumoniae infection Clinical suspicion of M. pneumoniae infection arises in a patient with a respiratory illness and any type of rash, but especially an erythema multiforme-like eruption. [dermnetnz.org]

  A continuing self-healing eruption, clinically bening - histologically malignant. Arch Dermatol. 1968;97:23-30. [ Links ] 10. El-Shabrawi-Caelen L, Kerl H, Cerroni L. Lymphomatoid papulosis. [scielo.br]

  Mycoplasma pneumoniae may with mucocutaneous eruptions related to erythema multiforme and Steven Johnson syndrome. Urticaria and anaphylactoid purpura are rare findings. [ncbi.nlm.nih.gov]

  Mycoplasma infections in humans are associated with skin eruptions in 17% of cases.[22]:293 Sexually transmitted infections[edit] Mycoplasma and Ureaplasma species are not part of the normal vaginal flora. [en.wikipedia.org]

• Meningism

  More rare complications include meningitis, brain abscess, endocarditis, wound infections, and bacteremia. Ureaplasma and M. hominis have been associated with bacteremia, pneumonia and meningoencephalitis in neonates. [infectiousdiseaseadvisor.com]

  The patient was conscious and alert, and exhibited no meningeal or focal neurologic signs. The blood tests performed at admission revealed a normal complete blood count and a mixed acid-base disorder with hyponatraemia and hypochloraemia (Table 1). [analesdepediatria.org]

  Congenital pneumonia, bacteremia, meningitis, and death have occurred in infants with very low birth weight due to Ureaplasma or Mycoplasma infection of the lower respiratory tract. [emedicine.medscape.com]

  […] severe disease Extrapulmonary manifestations of M. pneumoniae infection Syndromes caused by spread of organism Bullous hemorrhagic otitis Arthritis Acute respiratory distress syndrome Myocarditis with conduction disturbances and chest pain Encephalitis / meningitis [arupconsult.com]

  Maternal infection can lead to major neonatal complications such as pneumonia, bacteremia, and meningitis. [antimicrobe.org]

• Guillain-Barré Syndrome

  Detecting Guillain-Barré syndrome caused by Zika virus using systems developed for polio surveillance. http://www.who.int/bulletin/volumes/94/9/16-171504/en/. Published July 5, 2016. Accessed January 8, 2019. 15. [hologic.com]

  Skin rashes Erythema nodosum or erythema multiforme Thrombocytopenia Guillain-Barré syndrome ARUP Lab Tests Tests generally appear in the order most useful for common clinical situations. [arupconsult.com]

  Immunoadsorption therapy for a child with Guillain-Barré syndrome subsequent to Mycoplasma infection: a case study. Brain Dev 2005;27:431-433. [ Links ] 9. Falini A, Kesavadas C, Pontesilli S, Rovaris M, Scotti G. [scielo.br]

  It has been associated with other diseases, such as pleuropericarditis, pleuritis, reactive arthritis, predominantly cutaneous vasculitis, cold urticaria, lymphocytic meningitis, disseminated encephalomyelitis, Guillain–Barré syndrome, Adie syndrome and [analesdepediatria.org]

• Agitation

  Results of general physical examination were unremarkable, and neurologic examination revealed agitation, disorientation, but no focal findings. [jamanetwork.com]

  All steps of staining and washing were performed using slow agitation on an orbital mixer (50 rpm). [bmcmicrobiol.biomedcentral.com]

An extensive infectious and autoimmune workup was pursued. Mycoplasma IgM serology (enzyme immunoassay and confirmatory immunoflourescence) returned positive. She was treated with a course of azithromycin and IvIG with rapid improvement. [neurology.org]

The results of a full uveitis workup were negative for antinuclear antibody, rheumatoid factor, antineutrophil cytoplasmic antibody, HLA-B27, angiotensin-converting enzyme, Lyme disease, syphilis, and B henselae. [jamanetwork.com]

Admission laboratory workup revealed leukocyte count of 6.1 × 103 µL (reference range 4.5–11.0 × 103) with 72% neutrophils, hemoglobin of 16.2 g/dL (reference range 13.0–17.0), hematocrit of 48.2% (reference range 39–53), platelet count of 149 × 103 µL [hindawi.com]

• Gram-Positive Bacteria

  Murray proposed to divide the kingdom Bacteria into three divisions (= phyla) on the basis of the cell wall types: Gram-negative Gracilicutes, with a thin cell wall and little peptidoglycan; Gram-positive "Firmacutes", with a thicker cell wall and more [en.wikipedia.org]

  Mycoplasma are flask-shaped and are most likely descended from Gram-positive bacteria. Due to their seriously degraded genome they cannot perform many metabolic functions, such as cell wall production or synthesis of purines. [microbewiki.kenyon.edu]

  The class Mollicutes is the only class in the division Tenericutes (wall-less bacteria), which is at an equivalent taxonomic level to the gram-positive eubacteria, the gram-negative eubacteria, and the archaebacteria (comprising four divisions of the [globin.bx.psu.edu]

  In vitro data indicate that this agent has broad-spectrum activity against gram-positive and gram-negative bacteria, including organisms carrying fluoroquinolone-resistance determinants [59]. [academic.oup.com]

• Leukocytosis

  Additionally, these symptoms were accompanied by fever and elevated inflammatory markers, including leukocytosis, thrombocytosis, elevated C-reactive protein, and erythrocyte sedimentation rate. [pediatrics.aappublications.org]

  Laboratory Diagnosis Nonspecific Laboratory Diagnosis Roughly a third of patients with upper respiratory tract infection by M. pneumoniae can have leukocytosis and/or an elevated erythrocyte sedimentation rate. [scielo.br]

Plasmocin™ Treatment (25 mg/ml): to eliminate mycoplasmas, use at 25 µg/ml for 2 weeks. [invivogen.com]

Appropriate empirical antimicrobial treatment is necessary to achieve an optimal therapeutic outcome. [ncbi.nlm.nih.gov]

[…] previous treatment failure. [hindawi.com]

Treatment efficacy, treatment failures and selection of macrolide resistance in patients with high load of Mycoplasma genitalium during treatment of male urethritis with josamycin. BMC infectious diseases 2015;15:40. [mshc.org.au]

treatment group and from 1 of 3 (33%) in the 1000-mg group. [academic.oup.com]

Links: clinical features investigations treatment of mycoplasma pneumonia complications prognosis [gpnotebook.co.uk]

Patients with limited disease generally have an excellent prognosis. In the more advanced stages, the prognosis is poor. (WHO, 2001) [ 1 ] Mycosis fungoidess most frequently harbor alterations in ERBB4, AR, WT1, USP28, and TSHR [ 2 ]. [mycancergenome.org]

Prognosis The disease is slowly progressive (it may evolve over 10 to 30 years after the initial presentation). The prognosis depends on the stage at diagnosis. The documents contained in this web site are presented for information purposes only. [orpha.net]

Treatment and prognosis Most patients recover well although a small proportion of patients may develop bronchiectasis in the affected region or Swyer James syndrome. Promoted articles (advertising) [radiopaedia.org]

Defining the microbial etiology of culture-negative prosthetic joint infection (PJI) can be challenging. Metagenomic shotgun sequencing is a new tool to identify organisms undetected by conventional methods. [ncbi.nlm.nih.gov]

Mycoplasma pneumoniae is one of the main etiological agents of community-acquired pneumonia, although its incidence is generally unknown in Brazil. [scielo.br]

The etiologic agent of primary atypical pneumonia, it has also been implicated in both upper and lower respiratory tract infections, including tracheobronchitis, bronchitis and bronchiolitis. [uniprot.org]

These results point to an etiologic role for chronic infection in lung carcinogenesis. [doi.org]

Etiology The etiology remains unknown. Diagnostic methods The diagnosis is based on clinical presentation and should be confirmed by a skin biopsy. [orpha.net]

A few epidemiological studies, however, continue to raise concern over such a linkage. [ncbi.nlm.nih.gov]

It is characterised by hypertrophy of the gastric folds of the fundus and body, mucosal hypersecretion, protein loss and hypochlorhydria.1 Its pathophysiology has not been established, with different authors suggesting the possibility of infectious, autoimmune [analesdepediatria.org]

In sequencing these genomes researchers hope to increase understanding of the pathophysiology of the pathogen, by identifying virulence factors. [microbewiki.kenyon.edu]

Taken together, these studies show a relationship between M. genitalium infection and the female physiology, pregnancy, and pathophysiology. 3.3. [hindawi.com]

Pathophysiology Mycoplasma is an obligate parasite and primarily an extracellular pathogen that has developed a specialized organelle for attachment to host cells. [ncbi.nlm.nih.gov]

Plasmocin™ prophylactic can be used as a routine addition in liquid media to prevent mycoplasma and more generally bacterial contamination in mammalian cell cultures. [invivogen.com]

Catalog #: VZA-2021 Sales unit: items MycoZap TM Plus-CL Antibiotic formulation for prevention of bacteria, fungi and mycoplasma contaminations in cell line cultures. [bioscience.lonza.com]

Thermo Fisher Scientific has Mycoplasma detection kits and more resources on preventing and detecting contamination on its Mycoplasma Detection page. [thermofisher.com]