Presentation
We report the case of a 12-year-old patient who presented with acute onset of orofacial tics, motor restlessness, compulsive behavior, and cerebellar symptoms. Cerebrospinal fluid examination demonstrated lymphocytic meningitis. [ncbi.nlm.nih.gov]
An 11-year-old boy presented with a new onset seizure. [neurology.org]
The available literature regarding this subject is also presented. [content.iospress.com]
Patients with M pneumoniae –associated encephalitis are predominantly pediatric, and their presentations are clinically similar to enterovirus encephalitis, although they frequently require intensive care with prolonged hospitalizations. [pediatrics.aappublications.org]
Entire Body System
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Hypersomnia
Sugeno N, Kawaguchi N, Hasegawa T, Kuroda T, Nakashima I, et al. (2012) A case with anti-galactocerebroside antibody-positive Mycoplasma pneumoniae meningoencephalitis presenting secondary hypersomnia. Neurol Sci 33: 1473–1476. [journals.plos.org]
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Turkish
[…] associated MERS was conducted from November 2004 till August 2016 using PubMed and Google Scholar data base for Chinese-, Croatian-, Czech-, Danish-, English-, French-, German-, Hungarian-, Italian-, Korean-, Polish-, Portuguese-, Russian-, Spanish-, and Turkish-language [bmcinfectdis.biomedcentral.com]
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Pediatric Disease
Succinct, targeted coverage of normal childhood growth and development, as well as the diagnosis, management, and prevention of common pediatric diseases and disorders, make this an ideal medical reference book for students, pediatric residents, nurse [books.google.de]
Skin
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Kinky Hair
They have been associated with such conditions as cerebral palsy, residual brain damage, undefined infections, infantile neuroaxonal dystrophy, Menkes’ kinky-hair syndrome, and congenital muscular dystrophy. 2–4 There is one case report of extreme spindles [neurology.org]
Musculoskeletal
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Motor Restlessness
We report the case of a 12-year-old patient who presented with acute onset of orofacial tics, motor restlessness, compulsive behavior, and cerebellar symptoms. Cerebrospinal fluid examination demonstrated lymphocytic meningitis. [ncbi.nlm.nih.gov]
Psychiatrical
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Visual Hallucination
The clinical manifestations included fever (94%), altered consciousness (65%), seizure (41%), personality or behavior changes (29%), meningeal sign (24%), visual hallucination (24%), ataxia (12%), Guillain-Barré syndrome (6%), blurred vision (6%), and [ncbi.nlm.nih.gov]
Neurologic
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Dysarthria
Although these six patients completely recovered without sequela, dysarthria persisted in one patient with MERS and cerebellar lesions. Mild intellectual impairment persisted in one patient with limbic encephalitis. [ci.nii.ac.jp]
Workup
The routine diagnostic workup of M. pneumoniae encephalitis should therefore aim for the detection of M. pneumoniae antibodies in both CSF and serum, in addition to M. pneumoniae PCR in CSF. [journals.plos.org]
Workup should include a thorough history and physical exam to determine if the clinical course could be consistent with AE. [aealliance.org]
EEG
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Focal Epileptiform Discharges
This is supported by the EEG finding; normal to mild abnormality (i.e. slow wave) as in MERS by other causes [ 26 ] versus diffuse cortical dysfunction and focal epileptiform discharge in M.pneumoniae -associated encephalitis [ 27, 29 ]. [bmcinfectdis.biomedcentral.com]
Treatment
Treatment with corticosteroids has been proposed for this illness, but experience with this therapy is limited to case reports and small series; neither efficacy nor appropriate courses of treatment are well established. [ncbi.nlm.nih.gov]
Control 163 5 Vaccines 164 6 Political Issues 165 7 Ethics 166 References 167 RSV and Influenza Treatment and Prevention 169 14 Surfactant 170 17 Antiviral Treatment 171 22 Amantadine 172 25 Cold Adapted Influenza Vaccine CAIV 173 References 174 EncephalitisBeyond [books.google.de]
This case emphasizes the importance of CNS complications of M. pneumoniae and shows that corticosteroid therapy has a place for treatment of mycoplasma encephalitis. The available literature regarding this subject is also presented. [content.iospress.com]
View Article Google Scholar 39. van Doorn PA, Ruts L, Jacobs BC (2008) Clinical features, pathogenesis, and treatment of Guillain-Barré syndrome. Lancet Neurol 7: 939–950. View Article Google Scholar 40. [journals.plos.org]
Prognosis
Prognosis Encephalitis causes high rates of illness and death. [ 1 ] The prognosis depends on the age of the patient and the underlying aetiology. [patient.info]
Conclusions Prognosis of M.pneumoniae -associated MERS is excellent. Type II MERS may increase a risk of neurological sequelae. [bmcinfectdis.biomedcentral.com]
FLAIR : hyperintense DWI : hyperintense ADC: hypointense T1 C (Gd) : linear cranial nerve enhancement ring enhancement (abscess) heterogeneous if extensive inflammation MR spectroscopy : allows differentiation between abscess from tumor Treatment and prognosis [radiopaedia.org]
In addition, even experienced physicians often are uncertain about the cause, appropriate therapy, and prognosis. [pedsinreview.aappublications.org]
Etiology
Abstract Mycoplasma pneumoniae is an important etiologic agent of acute childhood encephalitis. [ncbi.nlm.nih.gov]
A hasty—and faulty—etiological diagnosis of disturbed family interaction caused additional suffering in a situation in which worries were already overwhelming. [link.springer.com]
Mycoplasma pneumoniae, a common respiratory pathogen, has been implicated as an etiology of encephalitis. [pediatrics.aappublications.org]
Epidemiology
153 7 Conclusion 154 Congenital Cytomegalovirus Infection Epidemiology and Treatment 155 13 Maternal Age 156 2 Therapeutic Interventions 157 3 Summary 158 References 159 Global Control of Rotavirus Disease 161 3 Epidemiology 162 4 Approaches to Disease [books.google.de]
Epidemiology of Mycoplasma pneumoniae infection in the British Isles, 1974—9. J Infect 1980; 2:191-194. Ramirez JA, Ahkee S, Tolentino A, Miller RD, Summersgill JT. [lci.rivm.nl]
Epidemiology Annual summary of respiratory Mycoplasma pneumoniae laboratory surveillance data England and Wales 2018 ( PDF, 467KB, 10 pages ) Laboratory reports of Mycoplasma pneumoniae infection made to CIDSC from PHE and NHS laboratories in England [gov.uk]
Epidemiology and clinical features of segmental/lobar pattern Mycoplasma pneumoniae pneumonia: a ten-year retrospective clinical study. Exp Ther Med. 2015;10:2337–44. [bmcinfectdis.biomedcentral.com]
"Epidemiology and outcomes of acute encephalitis". Current Opinion in Neurology. 28 (3): 277–82. doi : 10.1097/WCO.0000000000000199. PMID 25887770. Jmor F, Emsley HC, et al. (October 2008). [en.wikipedia.org]
Pathophysiology
"Encephalitis: Practice Essentials, Background, Pathophysiology". 2018-08-07. Archived from the original on 2015-08-03. Larner, A. J. (2013-05-02). Neuropsychological Neurology: The Neurocognitive Impairments of Neurological Disorders. [en.wikipedia.org]
Prevention
221 3 Vaccine Formulation 222 4 Immunological Memory 224 5 Carriage 225 7 Immunologies Issues in PracticeThe UK Experience 226 8 Conclusion 228 Strategies for Preventing Group B Streptococcal Disease 231 3 Tackling GBS Disease 232 4 Treatment or Prevention [books.google.de]
Prevention Exclusion from childcare, preschool, school or work is not necessary no vaccine is currently available cover a cough or sneeze with a tissue or your arm, not with your hand. [sahealth.sa.gov.au]
Preventing encephalitis It's not always possible to prevent encephalitis, but some of the infections that cause it can be prevented with vaccinations. [nhs.uk]
Prevention Vaccine is not available at the moment. [chp.gov.hk]