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Mycoplasma Genitalium


Presentation

  • Men infected with M. genitalium frequently present with dysuria, while women may present with or without urogenital symptoms.[ncbi.nlm.nih.gov]
  • Methods: Endocervical specimens were collected from women presenting with primary and secondary infertility and from fertile women as control group.[ncbi.nlm.nih.gov]
  • One or more pathogens were detected in 129 (43%) of the symptomatic men, with N. gonorrhoeae in 50 (16.7%); C. trachomatis in 37 (12.3%) and T. vaginalis present in 24 (8.0%) patients.[ncbi.nlm.nih.gov]

Workup

Rickettsia Rickettsii
  • Penetration of host cells by Rickettsia rickettsii appears to be mediated by a phospholipase of rickettsial origin.[ncbi.nlm.nih.gov]
HLA-B27
  • We report a case of reactive arthritis complicating M. genitalium urethritis in an HLA-B27-positive patient.[ncbi.nlm.nih.gov]

Treatment

  • […] the 1.5 g extended dose treatment.[ncbi.nlm.nih.gov]
  • Current guidelines recommend treatment with 1 gram of azithromycin; however, treatment failure has increasingly been reported. This meta-analysis estimates treatment efficacy following treatment with 1 gram of azithromycin.[ncbi.nlm.nih.gov]
  • Nine sets of specimens obtained before and after treatment from patients who experienced azithromycin treatment failure were examined with use of sequencing of polymerase chain reaction products.[ncbi.nlm.nih.gov]

Etiology

  • Mycoplasma genitalium is an etiological agent of sexually transmitted infections, but due to its fastidious growth requirements, only a few M. genitalium strains are available for determination of the activity of currently used and new antimicrobial agents.Recent[ncbi.nlm.nih.gov]
  • In some populations, M. genitalium is significantly associated with HIV-1 infection, and is also an etiological agent in pelvic inflammatory disease.[ncbi.nlm.nih.gov]

Epidemiology

  • Transcription-mediated amplification has additionally identified novel facets of M. genitalium and T. vaginalis epidemiology that warrant further investigation.[ncbi.nlm.nih.gov]
  • Author information 1 Department of Epidemiology, Tulane University School of Public Health. 2 Department of Internal Medicine, Section of Infectious Diseases, Louisiana State University Health Sciences Center, New Orleans. 3 Departments of Epidemiology[ncbi.nlm.nih.gov]
  • This article summarizes the epidemiologic evidence linking Mycoplasma genitalium to sexually transmitted disease syndromes, including male urethritis, and female cervicitis, pelvic inflammatory disease, infertility, and adverse birth outcomes.[ncbi.nlm.nih.gov]
  • Such clear epidemiological correlation has to our knowledge not been published before. The urethral infections led to clinical symptoms, but the rectal infections did not.[ncbi.nlm.nih.gov]
  • Collectively, the basic scientific discussions herein should provide a framework for understanding the clinical and epidemiological outcomes described in the accompanying articles in this supplemental issue. The Author 2017.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Prospective studies on the prevalence, pathophysiology, and long-term reproductive consequences of M. genitalium infection in the general population are needed to determine if screening protocols are necessary.[ncbi.nlm.nih.gov]
  • Useful For Suggests clinical disorders or settings where the test may be helpful Rapid, sensitive, and specific identification of Mycoplasma genitalium from genitourinary and reproductive sources Clinical Information Discusses physiology, pathophysiology[mayomedicallaboratories.com]

Prevention

  • KEYWORDS: Mycoplasma genitalium; prevention; public health[ncbi.nlm.nih.gov]
  • Understanding the role of infectious agents on cancer development might be useful for developing new approaches to its prevention.[doi.org]
  • The European Centre for Disease Prevention and Control and the European Office of the World Health Organisation also contributed to their development. 2016 European Academy of Dermatology and Venereology.[ncbi.nlm.nih.gov]
  • Prevention of Mycoplasma Genitalium Like most STIs, Mycoplasma Genitalium infections can be prevented by using a condom during sexual contact.[novosanis.com]

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