Presentation
The focus was on the 46-kDa protein that is present in M. penetrans strain HF-2 but not in the type strain, GTU. [ncbi.nlm.nih.gov]
Entire Body System
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Intravenous Drugs
Abstract Antibodies to Mycoplasma penetrans were found at an unusually high frequency in male homosexuals with AIDS (55 of 149; 37%) and in human immunodeficiency virus (HIV)-infected asymptomatic homosexuals (13 of 49; 26.5%) but not in intravenous drug [ncbi.nlm.nih.gov]
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Pathologist
After the double staining with lead and uranium, sections were examined under transmission electron microscope and photographed by a senior pathologist. [doi.org]
Respiratoric
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Respiratory Distress
Three days before hospital admission, she became ill with respiratory distress, generalized weakness, anorexia, and inability to walk. [doi.org]
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Pertussis
Here, we describe a 78-kDa protein from M. penetrans, designated MYPE9110, that exhibits sequence similarity to known ADP-ribosyltransferases (ADPRTs) such as Bordetella pertussis pertussis toxin and Mycoplasma pneumoniae community-acquired respiratory [ncbi.nlm.nih.gov]
Cardiovascular
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Hypertension
On admission to the hospital (day 1), physical examination showed severe pallor, a swollen cervical lymph node, slight edema of both legs, tachycardia, and no hypertension. [doi.org]
Workup
Microbiology
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Helicobacter Pylori
Carcinogenesis of Helicobacter pylori. Gastroenterology 133 : 659–672. De Marzo AM, Platz EA, Sutcliffe S, Xu J, Grönberg H, Drake CG et al. (2007). Inflammation in prostate carcinogenesis. Nat Rev Cancer 7 : 56–69. [doi.org]
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Bordetella Pertussis
Here, we describe a 78-kDa protein from M. penetrans, designated MYPE9110, that exhibits sequence similarity to known ADP-ribosyltransferases (ADPRTs) such as Bordetella pertussis pertussis toxin and Mycoplasma pneumoniae community-acquired respiratory [ncbi.nlm.nih.gov]
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Staphylococcus Aureus
The 46-kDa protein band was excised from the gel and treated with Staphylococcus aureus V8 protease (Sigma-Aldrich, Steinheim, Germany). [doi.org]
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Giardia Lamblia
(D) Topology-based sequence alignment of CK from Mycoplasma penetrans, Enterococcus faecalis, Pyrococcus furiosus and Giardia lamblia. [doi.org]
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Pseudomonas
(D) Topology-based sequence alignment of ADI from Mycomplasma penetrans, Mycoplasma arginini and Pseudomonas aeruginosa. [doi.org]
Treatment
In addition, proteinase K treatment of the M. penetrans cells resulted in removal of the capsule, suggesting that polypeptides may contribute in anchoring it to the membrane or in its stability. [ncbi.nlm.nih.gov]
On day 3, the antibiotic treatment was changed to ceftazidime (1 gm q8h i.v.). [doi.org]
There have also been cases of malignant pleural effusion, when patients exhibited chronic M. penetrans infection with various immunodeficiencies (such as HIV infections or anticancer treatment). [en.wikipedia.org]
Etiology
Mycoplasma penetrans, a rare bacterium so far only found in HIV-infected persons, was isolated in the blood and throat of a non-HIV-infected patient with primary antiphospholipid syndrome (whose etiology and pathogenesis are unknown). [ncbi.nlm.nih.gov]
The analysis of the results will allow to decide on algorithms to be used for the etiologic diagnosis of CAP. [uantwerpen.be]
One application of multiplex PCR is to increase the ability of clinicians to determine the causative agent in diseases with an unknown etiology such as CFS, FMS, RA, and GWS. [thearthritiscenter.com]
Birmingham, Birmingham, Alabama, USA Cite This Article Abstract Mycoplasma penetrans, a rare bacterium so far only found in HIV-infected persons, was isolated in the blood and throat of a non-HIV-infected patient with primary antiphospholipid syndrome (whose etiology [wwwnc.cdc.gov]
[…] respiratory tract with bacteremic dissemination, particularly in persons with antibody deficiencies, indicating the importance of the humoral immune system in host defense against these organisms. [9] Ureaplasma species are the most common nonbacterial etiologies [emedicine.medscape.com]
Epidemiology
M. penetrans is apparently transmitted sexually through homosexual activity and is epidemiologically linked to formation of KS in homosexual men with AIDS. Parallel tests with M. genitalium revealed no similar link to KS in the same study sample. [ncbi.nlm.nih.gov]
An epidemiological survey of Mycoplasma hominis and Ureaplasma urealyticum in gynaecological outpatients, Rome, Italy. Epidemiology & Infection 2013 ; 141 : 2650 – 2657. 13. Haggerty, CL, Ness, RB. [cambridge.org]
Epidemiology, clinical manifestations, pathogenesis and laboratory detection of Mycoplasma pneumoniae infections. FEMS Microbiol. Rev. 2008, 32, 956-973. Go to original source... Go to PubMed... [mmsl.cz]
Epidemiology, clinical manifestations, pathogenesis and laboratory detection of Mycoplasma pneumoniae infections. FEMS Microbiol. Rev. 32 :956-973. Balish, M.F., and D.C. Krause. 2006. Mycoplasmas: a distinct cytoskeleton for wall-less bacteria. J. [miamioh.edu]
Prevention
A marked decrease in the extent of vacuolation was observed when peroxide accumulation was partially prevented by alpha-tocopherol. [ncbi.nlm.nih.gov]
Hence, more attention should be paid to prevention and treatment of Mpe infection in patients with immunodeficiency. [doi.org]