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Mycoplasma Pneumoniae


Presentation

  • Abstract We report 3 previously normal children that presented for evaluation of new onset seizures.[ncbi.nlm.nih.gov]
  • To the best of our knowledge, this is the first case presenting monosymptomatic visual loss without papillitis, neurological symptoms, and abnormal findings on brain imaging.[ncbi.nlm.nih.gov]
  • Presented is a patient with likely Mycoplasma pneumoniae infection and progression to TEN. A 19-year-old male presented with 1-week history of pneumonia like symptoms and prescribed antibiotics for suspected community-acquired pneumonia.[ncbi.nlm.nih.gov]
  • In this cohort, 17 children (26%) had a severe form of GBS and 47% of patients with M. pneumoniae infection presented with severe GBS.[ncbi.nlm.nih.gov]
  • We report coinfection of Mycoplasma pneumoniae in swine influenza A H1N1 child who presented with extensive pneumonia and expired within 48 hours.[ncbi.nlm.nih.gov]
Dysarthria
  • Symptoms are usually hemiplegia and dysarthria. We report a case of a 6-year-old boy who suffered cortical blindness due to a stroke 2 days after M. pneumoniae infection.[ncbi.nlm.nih.gov]
Tonic-Clonic Seizure
  • Case 3, an 11-year-old male, presented with a generalized tonic clonic seizure and worsening hallucinations responding to intravenous corticosteroids and 1 antiepileptic medication.[ncbi.nlm.nih.gov]
Areflexia
  • A 38-yr-old man who had been treated with antibiotics for serologically proven M. pneumoniae pneumonia presented with a sudden onset of diplopia, ataxic gait, and areflexia.[ncbi.nlm.nih.gov]

Workup

  • The complexity of aHUS, and the importance of the requirement for full differential diagnostic workup of all HUS cases is further highlighted by the current case history.[ncbi.nlm.nih.gov]
  • The results of a full uveitis workup were negative for antinuclear antibody, rheumatoid factor, antineutrophil cytoplasmic antibody, HLA-B27, angiotensin-converting enzyme, Lyme disease, syphilis, and B henselae .[jamanetwork.com]
  • Laboratory workup revealed a Hemoglobin of 13.5 g/ dL, leukocytosis of 23,700 c/mm 3 and platelet count of 57,000 c/mm 3 . Moderate renal insufficiency was also present with a creatinine of 2.02.[bloodjournal.org]
Right Pleural Effusion
  • She completed treatment with no noticeable adverse events, and the right pleural effusion disappered and diffuse right pleural thickening improved.[ncbi.nlm.nih.gov]
Human Herpesvirus 6
  • Human herpesvirus 6 (HHV-6) is the only virus known to integrate into human chromosomes and be transmitted from parents to offspring. Less than 1% of the population carries integrated HHV-6 in their genomes.[ncbi.nlm.nih.gov]
Plasmodium Falciparum
  • Plasmodium falciparum and Mycoplasma pneumoniae co-infection occurring in vivo manifests clinical features that are plausibly a result of the interaction between the two microorganisms.[ncbi.nlm.nih.gov]

Treatment

  • CONCLUSION: A macrolide-resistant population might develop in individual patients up to 24 days after initiation of macrolide treatment.[ncbi.nlm.nih.gov]
  • RESULTS: Seven days after enrollment, the average F 2 after treatment of group A was the shortest.[ncbi.nlm.nih.gov]
  • Currently, no clear treatment guidelines have been established for its treatment using glucocorticoid and immunosuppressive. In this study, we report an adult who admitted to our hospital due to fever and gross hematuria.[ncbi.nlm.nih.gov]
  • QTF treatment also decreased TM expression. In conclusion, QTF treatment inhibited the progression of MPP, reduced vascular permeability, and improved pulmonary microcirculation more effectively than conventional treatment with Western medicine.[ncbi.nlm.nih.gov]
  • A total of 120 wistar rats were randomly divided into 5 groups: a normal group, infection group, Qingfei Mixture treatment group, azithromycin treatment group, and Qingfei Mixture azithromycin treatment group.[ncbi.nlm.nih.gov]

Prognosis

  • Mycoplasma pneumoniae-induced acute postinfectious glomerulonephritis has various pathological changes and relatively poor prognosis. It often occurs in children, barely in adults.[ncbi.nlm.nih.gov]
  • Related articles about ON after M. pneumoniae infection were reviewed to summarize the clinical presentation, possible mechanisms, clinical survey, treatment, and prognosis of this condition.[ncbi.nlm.nih.gov]
  • Owing to different therapeutic approaches and the way these affect the prognosis, the early and correct diagnostic determination of the etiology of a cardiac mass is of utmost importance and essential for the appropriate management of patients.We report[ncbi.nlm.nih.gov]
  • Although montelukast had little effect on improving the immune function, it was certainly beneficial for controlling the symptoms of asthma and improving the prognosis.[ncbi.nlm.nih.gov]
  • Prognosis of M.pneumoniae-associated MERS is excellent. Type II MERS may increase a risk of neurological sequelae.[ncbi.nlm.nih.gov]

Etiology

  • It is well known that the most important etiologies of acute pancreatitis are gallstones and alcohol consumption.[ncbi.nlm.nih.gov]
  • Mycoplasma is a well-documented etiology of SJS, but rarely documented as an etiology of TEN. This case suggests the potential of Mycoplasma infection causing more severe mucocutaneous disease in the spectrum of SJS and TEN.[ncbi.nlm.nih.gov]
  • Some of the biomarkers used for etiologic diagnosis in children with CAP and they also have been used the MP infection severity.[ncbi.nlm.nih.gov]
  • Delay in identification of M. pneumoniae infection in this case prompted treatment with systemic and topical steroids for presumed autoimmune etiology.[ncbi.nlm.nih.gov]
  • Etiological research showed positivity of IgM antibodies to Mycoplasma pneumoniae after seven days of admission. The child has been successfully treated with antibiotic therapy, without the use of macrolides, for a duration of 4 weeks.[ncbi.nlm.nih.gov]

Epidemiology

  • […] real-time PCR Publication type, MeSH terms, Substances Publication type Multicenter Study MeSH terms Adolescent Anti-Bacterial Agents/therapeutic use Child Child, Preschool Drug Resistance, Bacterial/genetics* Female Humans Infant Infant, Newborn Japan/epidemiology[ncbi.nlm.nih.gov]
  • Weekly Epidemiological Record Relevé épidémiologique hebdomadaire, 56 (‎39)‎, 310.[apps.who.int]
  • Keywords: Atypical bacterial pneumonia, CAP, epidemiology, Mycoplasma pneumoniae.[eurekaselect.com]
  • Clinical and epidemiological features of Mp PCR-positive and -negative children were compared using logistic regression. Macrolide susceptibility was assessed by genotyping isolates.[ncbi.nlm.nih.gov]
  • Medical CenterRotterdam, Netherlands; Laboratory of Pediatrics, Division of Pediatric Infectious Diseases and Immunology, Erasmus MC-Sophia Children's Hospital, University Medical CenterRotterdam, Netherlands; Division of Infectious Diseases and Hospital Epidemiology[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • The pathophysiology of this process remains unknown.[ncbi.nlm.nih.gov]
  • Thus, the pathophysiology of MP-HLH may differ from that of EBV-HLH.[ncbi.nlm.nih.gov]
  • Evidence of central nervous system inflammation in the absence of direct infection suggests an immune-mediated pathophysiology.[ncbi.nlm.nih.gov]
  • The pathophysiology of this disorder may be post-infectious and autoimmune.[ncbi.nlm.nih.gov]
  • Useful For Suggests clinical disorders or settings where the test may be helpful Diagnosis of infections due to Mycoplasma pneumoniae Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory[mayomedicallaboratories.com]

Prevention

  • Therefore, the implementation of effective and practical prevention measures has become an urgent need.[ncbi.nlm.nih.gov]
  • Centers for Disease Control Collaboration, Nonthaburi, Thailand. 4 Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.[ncbi.nlm.nih.gov]
  • Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00207584 Centers for Disease Control and Prevention Principal Investigator: Julia A Schillinger, MD Centers for Disease Control and Prevention Additional relevant MeSH terms[clinicaltrials.gov]
  • The identification of triggers related to this pathology can allow new therapeutic targets or preventive strategies.[ncbi.nlm.nih.gov]
  • So it is essential for pediatricians to recognize severe or refractory or severe MP early, treat it promptly and prevent the progress of the disease. In recent years, several new biomarkers have been tested in children with CAP.[ncbi.nlm.nih.gov]

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