Presentation
The aim of the present study was to assess the exposure of Catalonian population to the combined mycotoxins T2 and HT2. [ncbi.nlm.nih.gov]
Even if a toxigenic fungus is present, it does not necessarily mean that the mold is producing toxins. [mycotoxintestinglab.com]
Some of these substances may be present as contaminants from mold or may occur naturally in foodstuffs or in livestock feeds. Symptoms may occur among exposed humans or animals. [emergency.cdc.gov]
Mycotoxin Detection Solutions Mycotoxins are found in almost all types of agricultural feedstuffs and grains, which has been a major concern with regards to feed contamination and presents a genuine risk to livestock animal production. [elabscience.com]
Hardtmann - U27186 | 2015 Corporate Presentation. About Bühler. 3 | © Bühler | Gluten free pasta production – basic technological aspects. | S. Hardtmann - U27186 | 2015 Bühler at a glance. [buhlergroup.com]
Entire Body System
- Weakness
Symptoms and signs Skin Local pain Pruritus Skin redness Vesicle s Skin necrosis and sloughing Respiratory Nose and throat pain Nasal discharge Itch ing and sneezing Cough Dyspnea Wheezing Chest Pain Hemoptysis Severe systemic Prostration Weakness Ataxia [fpnotebook.com]
Paralysis of the skeletal muscles follows with a proportional, downward and growing weakness that may result in sudden respiratory failure. [firehouse.com]
The symptoms of chemical toxicity are typically neurological and include headache, extreme fatigue, dizziness, weakness, nausea, disorientation, memory problems, slowed reaction time, peripheral neuropathy, sensory neuropathy, and personality/mood changes [spoonielife.wordpress.com]
Systemic symptoms can develop with all routes of exposure (especially inhalation) and might include weakness, ataxia, hypotension, coagulopathy, and death (1). [emergency.cdc.gov]
Systemic symptoms can develop with all routes of exposure and might include weakness, ataxia, hypotension, coagulopathy, and death. In airborne form, Trichothecene mycotoxins can be dispersed through the air or mixed in food or beverages. [globalsecurity.org]
- Pain
Symptoms and signs Skin Local pain Pruritus Skin redness Vesicle s Skin necrosis and sloughing Respiratory Nose and throat pain Nasal discharge Itch ing and sneezing Cough Dyspnea Wheezing Chest Pain Hemoptysis Severe systemic Prostration Weakness Ataxia [fpnotebook.com]
Cx typically occur within 1 hr of exposure B - balance, loss of - bladder and kidney pain - bleeding lungs - blood pressure irregularities - body aches and muscle pains - boils on skin, especially neck, especially following disturbance of moldy materials [o2wizard.com]
When nasal mucosa is exposed to mycotoxins, this produces nasal pain, sneezing, rhinorrhea, dyspnea, wheezing, cough, and blood tinged saliva and sputum. Exposure of the eyes to mycotoxins produces eye pain, tearing, redness, and blurred vision. [mycotoxintestinglab.com]
Chronic inflammation goes rampant in the body and brain, resulting in debilitating wide-spread chronic pain and fatigue, a profound list of progressive symptoms, and irreversible damage. [spoonielife.wordpress.com]
Symptoms included vomiting, dizziness, seizures, and respiratory malaise, and survivors would continue to suffer from joint pains, memory loss, and rashes. [globalsecurity.org]
- Fever
However, these irritant effects are transient and self-limiting H - hair loss - headaches - heart attack - Hypersensitivity Pneumonitis - (Extrinsic Allergic Alveolitis) - tightness of chest, difficulty breathing, cough, fever, muscle aches, reactions [o2wizard.com]
These include SEB, Q-Fever, tularemia, plague and some of the chemical agents. Treatment for victims of ricin poisoning remains supportive. [firehouse.com]
A: An allergy produces hay fever-like symptoms such as sneezing, runny nose, itching, nasal stuffiness, watering eyes, wheezing, and coughing. Allergy symptoms, while difficult, are generally regarded as different degrees of a nuisance. [spoonielife.wordpress.com]
In 1940, Soviet scientists coined the term stachybotryotoxicosis to describe the acute syndrome (sore throat, bloody nasal discharge, dyspnea, cough, and fever) resulting from the inhalation of Stachybotrys mycotoxin. [emedicine.medscape.com]
These progress into fever, chills, myalgias, and bone marrow depression causing granulocytopenia and sepsis. [mycotoxintestinglab.com]
- Fatigue
Chronic inflammation goes rampant in the body and brain, resulting in debilitating wide-spread chronic pain and fatigue, a profound list of progressive symptoms, and irreversible damage. [spoonielife.wordpress.com]
Other Systemic Symptoms. - Fatigue, headache and/or irritability. [o2wizard.com]
Deoxynivalenol Diacetoxyscirpenol HT-2 mycotoxins Neosolaniol Nivalenol Satratoxin-H T-2 mycotoxins Verrucarin A Vomitoxin Trichothecene Mycotoxin Symptoms Exposure to trichothecene mycotoxins can cause these symptoms in people: Dry eyes Tiredness, fatigue [moldpedia.com]
The most common symptoms of mycotoxins exposure include diarrhoea, headaches, skin irritation and fatigue and in worst cases also impaired or altered immune function. [blackmould.me.uk]
- Inflammation
[…] contaminated bird droppings or construction dusts G - Glucan sensitivity: Glucans are glucose polymers that are components of most fungal cell walls, and exposure to airborne 13-beta-D-glucan has been known to cause irritation symptoms due to airway inflammation [o2wizard.com]
Chronic inflammation goes rampant in the body and brain, resulting in debilitating wide-spread chronic pain and fatigue, a profound list of progressive symptoms, and irreversible damage. [spoonielife.wordpress.com]
It should be noted that an explosion proof blender is recommended for use with inflammable solvents such as acetone and methanol. [fao.org]
Little data is available on human inhalation exposure, but victims would be expected to develop severe lung inflammation with a progressive cough, dyspnea, cyanosis and pulmonary edema. [firehouse.com]
Respiratoric
- Cough
anaphylaxis - apnea, sleep - Aspergilloma (fungal growth in lung), cough, coughing up blood, weight loss. [o2wizard.com]
Symptoms and signs Skin Local pain Pruritus Skin redness Vesicle s Skin necrosis and sloughing Respiratory Nose and throat pain Nasal discharge Itch ing and sneezing Cough Dyspnea Wheezing Chest Pain Hemoptysis Severe systemic Prostration Weakness Ataxia [fpnotebook.com]
During the 1940s, humans were accidentally exposed to sub-lethal doses that produced fever, chest tightness, cough, dyspnea, nausea and arthralgias within four to eight hours. [firehouse.com]
A: An allergy produces hay fever-like symptoms such as sneezing, runny nose, itching, nasal stuffiness, watering eyes, wheezing, and coughing. Allergy symptoms, while difficult, are generally regarded as different degrees of a nuisance. [spoonielife.wordpress.com]
Ocular exposure might result in blurred vision, and inhalational exposure might cause nasal irritation and cough. [emergency.cdc.gov]
- Sneezing
Symptoms and signs Skin Local pain Pruritus Skin redness Vesicle s Skin necrosis and sloughing Respiratory Nose and throat pain Nasal discharge Itch ing and sneezing Cough Dyspnea Wheezing Chest Pain Hemoptysis Severe systemic Prostration Weakness Ataxia [fpnotebook.com]
Rhinitis, sneezing and/or wheezing. - Central nervous system. Anxiety, depression, memory deficits and/or loss of ability to concentrate. - Menstrual abnormalities. Severe premenstrual tension and/or menstrual irregularities. [o2wizard.com]
A: An allergy produces hay fever-like symptoms such as sneezing, runny nose, itching, nasal stuffiness, watering eyes, wheezing, and coughing. Allergy symptoms, while difficult, are generally regarded as different degrees of a nuisance. [spoonielife.wordpress.com]
When nasal mucosa is exposed to mycotoxins, this produces nasal pain, sneezing, rhinorrhea, dyspnea, wheezing, cough, and blood tinged saliva and sputum. Exposure of the eyes to mycotoxins produces eye pain, tearing, redness, and blurred vision. [mycotoxintestinglab.com]
When inhaled, the symptoms include itching and pain, sneezing, epistaxis (bleeding from the nose) and rhinorrhea. Other symptoms include pulmonary/tracheobronchial toxicity by dyspnea, wheezing, and cough. [firehouse.com]
- Dyspnea
Symptoms and signs Skin Local pain Pruritus Skin redness Vesicle s Skin necrosis and sloughing Respiratory Nose and throat pain Nasal discharge Itch ing and sneezing Cough Dyspnea Wheezing Chest Pain Hemoptysis Severe systemic Prostration Weakness Ataxia [fpnotebook.com]
- asthma and asthmatic signs - asthma, adult onset - asthma, sudden onset, any age - asthma, increased symptoms or renewal of previously diminished symptoms - Asthma due to fungal allergens: chest tightness, wheezing, cough, dyspnea. [o2wizard.com]
During the 1940s, humans were accidentally exposed to sub-lethal doses that produced fever, chest tightness, cough, dyspnea, nausea and arthralgias within four to eight hours. [firehouse.com]
In 1940, Soviet scientists coined the term stachybotryotoxicosis to describe the acute syndrome (sore throat, bloody nasal discharge, dyspnea, cough, and fever) resulting from the inhalation of Stachybotrys mycotoxin. [emedicine.medscape.com]
When nasal mucosa is exposed to mycotoxins, this produces nasal pain, sneezing, rhinorrhea, dyspnea, wheezing, cough, and blood tinged saliva and sputum. Exposure of the eyes to mycotoxins produces eye pain, tearing, redness, and blurred vision. [mycotoxintestinglab.com]
- Nasal Discharge
Symptoms and signs Skin Local pain Pruritus Skin redness Vesicle s Skin necrosis and sloughing Respiratory Nose and throat pain Nasal discharge Itch ing and sneezing Cough Dyspnea Wheezing Chest Pain Hemoptysis Severe systemic Prostration Weakness Ataxia [fpnotebook.com]
In 1940, Soviet scientists coined the term stachybotryotoxicosis to describe the acute syndrome (sore throat, bloody nasal discharge, dyspnea, cough, and fever) resulting from the inhalation of Stachybotrys mycotoxin. [emedicine.medscape.com]
Recurrent episodes of Candida vaginitis associated with the classic symptoms of pruritus, burning and abnormal discharge. - Gastrointestinal. Heartburn, bloating, diarrhea or constipation. - Respiratory allergy. [o2wizard.com]
- Rhinorrhea
When nasal mucosa is exposed to mycotoxins, this produces nasal pain, sneezing, rhinorrhea, dyspnea, wheezing, cough, and blood tinged saliva and sputum. Exposure of the eyes to mycotoxins produces eye pain, tearing, redness, and blurred vision. [mycotoxintestinglab.com]
When inhaled, the symptoms include itching and pain, sneezing, epistaxis (bleeding from the nose) and rhinorrhea. Other symptoms include pulmonary/tracheobronchial toxicity by dyspnea, wheezing, and cough. [firehouse.com]
Gastrointestinal
- Vomiting
Deoxynivalenol Toxin produced by Fusarium molds which causes livestock feed refusal, vomiting and interferes with growth and development. [vicam.com]
Symptoms included vomiting, dizziness, seizures, and respiratory malaise, and survivors would continue to suffer from joint pains, memory loss, and rashes. [globalsecurity.org]
Diacetoxyscirpenol HT-2 mycotoxins Neosolaniol Nivalenol Satratoxin-H T-2 mycotoxins Verrucarin A Vomitoxin Trichothecene Mycotoxin Symptoms Exposure to trichothecene mycotoxins can cause these symptoms in people: Dry eyes Tiredness, fatigue General discomfort Vomiting [moldpedia.com]
[…] vaginal yeast infections - wee Women' health problems (below) - vertigo or dizziness - VOC sensitivity: volatile chemicals may reach levels sufficient to produce central nervous system symptoms such as headache, inability to concentrate, or dizziness - vomiting [o2wizard.com]
Mylar Flush (neurological) Large boils on neck Burning after urination, frequent urination, dark urine Insensitivity to heat and alcohol Nose bleeds (stachybotrys) Coughing up blood, black looking debris Difficulty swallowing, choking, spitting up (vomiting [spoonielife.wordpress.com]
- Abdominal Pain
pain Mental impairment Rash Bleeding There is more information about the symptoms of trichothecenes at the Toxic Black Mold Symptoms page. [moldpedia.com]
If the mycotoxins are ingested, they produce a lethal illness called alimentary toxic aleukia (ATA) with the following initial symptoms: abdominal pain, diarrhea, vomiting, and prostration. [mycotoxintestinglab.com]
200 Mold, (Odor & Bacteria) Related Illnesses and Health Complaints, both Medical and Anecdotal A - abdominal pain - abnormal pap smears - acid reflux - acne - allergy symptoms (wide variety of) - mild to severe and from transitory to chronic - Ref: Middleton [o2wizard.com]
pains, stomach lesions Joint and muscle stiffness, pain and weakness Cognitive dysfunction (progressive brain fog); memory loss, slurred speech, confusion, dementia Balance problems, dizziness, vertigo Ringing in ears, loss of hearing (aspergillus niger [spoonielife.wordpress.com]
- Nausea
The symptoms of chemical toxicity are typically neurological and include headache, extreme fatigue, dizziness, weakness, nausea, disorientation, memory problems, slowed reaction time, peripheral neuropathy, sensory neuropathy, and personality/mood changes [spoonielife.wordpress.com]
During the 1940s, humans were accidentally exposed to sub-lethal doses that produced fever, chest tightness, cough, dyspnea, nausea and arthralgias within four to eight hours. [firehouse.com]
[…] infections - wee Women' health problems (below) - vertigo or dizziness - VOC sensitivity: volatile chemicals may reach levels sufficient to produce central nervous system symptoms such as headache, inability to concentrate, or dizziness - vomiting (nausea [o2wizard.com]
Cardiovascular
- Chest Pain
Symptoms and signs Skin Local pain Pruritus Skin redness Vesicle s Skin necrosis and sloughing Respiratory Nose and throat pain Nasal discharge Itch ing and sneezing Cough Dyspnea Wheezing Chest Pain Hemoptysis Severe systemic Prostration Weakness Ataxia [fpnotebook.com]
Fungus: doctorfungus.org - central nervous system disorders (CNS) - chest pain associated with excessive coughing - chills - choking - cholesterol or triglycerides unusual variations - chronic fatigue syndrome (CFS) - chronic sinus infections - coated [o2wizard.com]
Some patients may also exhibit shortness of breath and retrosternal (behind the breast bone) type of chest pain. Fevers of between 103 and 106 degrees Fahrenheit generally last for two to five days and a cough may persist for several weeks. [firehouse.com]
- Tachycardia
Balance problems, dizziness, vertigo Ringing in ears, loss of hearing (aspergillus niger) Chronic allergies, congestion, sneezing, sinusitis Asthma, wheezing, shortness in breath, coughing, chronic bronchitis Heart palpitations, irregular heart beat, tachycardia [spoonielife.wordpress.com]
Once the mycotoxins enter the system, symptoms include weakness, prostration, dizziness, ataxia, loss of coordination, and in fatal cases, tachycardia, hypothermia, and hypotension. Death may occur in minutes, hours, or days. Diagnosis. [mycotoxintestinglab.com]
When victims have been exposed to lethal doses, tachycardia, hypothermia and hypotension follow. Death may occur in minutes, hours or days. Decontamination of victims is very important to remove the mycotoxins from the skin and eyes. [firehouse.com]
Skin
- Blister
Dermal exposure in some situations could lead to burning pain, redness, and blisters, and oral exposure may lead to vomiting and diarrhea. [emergency.cdc.gov]
While larger amounts of T-2 toxin is required for a lethal dose than for other chemical warfare agents such as VX, soman, or sarin, its potent effect as a blistering agent is well noted. [emedicine.medscape.com]
Dermal exposure leads to burning pain, redness, and blisters, and oral exposure leads to vomiting and diarrhea. Ocular exposure might result in blurred vision, and inhalational exposure might cause nasal irritation and cough. [globalsecurity.org]
When skin is exposed to mycotoxins, burning, redness, blistering, and skin necrosis occur. When nasal mucosa is exposed to mycotoxins, this produces nasal pain, sneezing, rhinorrhea, dyspnea, wheezing, cough, and blood tinged saliva and sputum. [mycotoxintestinglab.com]
Initial symptoms include burning skin pain, redness, tenderness, blistering, and progression to skin necrosis (tissue death) with leathery blackening and sloughing of large areas of skin in lethal cases. [firehouse.com]
- Flushing
called the Mylar Flush (neurological) Large boils on neck Burning after urination, frequent urination, dark urine Insensitivity to heat and alcohol Nose bleeds (stachybotrys) Coughing up blood, black looking debris Difficulty swallowing, choking, spitting [spoonielife.wordpress.com]
[…] rashes - diarrhea - difficulty concentrating - difficulty in swallowing - dirt-like taste in mouth - disorientation - dizziness E - endometriosis - eye infections, (beware of undiagnosed fungal eye infections), loss of vision - eye irritation F - face flushing [o2wizard.com]
- Pruritus
Symptoms and signs Skin Local pain Pruritus Skin redness Vesicle s Skin necrosis and sloughing Respiratory Nose and throat pain Nasal discharge Itch ing and sneezing Cough Dyspnea Wheezing Chest Pain Hemoptysis Severe systemic Prostration Weakness Ataxia [fpnotebook.com]
Recurrent episodes of Candida vaginitis associated with the classic symptoms of pruritus, burning and abnormal discharge. - Gastrointestinal. Heartburn, bloating, diarrhea or constipation. - Respiratory allergy. [o2wizard.com]
Face, Head & Neck
- Epistaxis
If the patient survives these initial stages, the next set of symptoms are painful pharyngeal/laryngeal ulceration and diffuse bleeding into the skin, bloody diarrhea, hematuria, hematemesis, epistaxis, and vaginal bleeding. [mycotoxintestinglab.com]
When inhaled, the symptoms include itching and pain, sneezing, epistaxis (bleeding from the nose) and rhinorrhea. Other symptoms include pulmonary/tracheobronchial toxicity by dyspnea, wheezing, and cough. [firehouse.com]
Neurologic
- Irritability
الصفحة 128 - Irritant: A chemical, which is not corrosive, but which causes a reversible inflammatory effect on living tissue by chemical action at the site of contact. [books.google.com]
Other Systemic Symptoms. - Fatigue, headache and/or irritability. [o2wizard.com]
Local infections such as ringworm and thrush are also fungi infections.ii Irritants: Fungi can cause skin irritation and irritation of the eyes and nose. Allergens: To an allergist, Fungi are at the bottom of the list for allergic sensitization. [mycotoxintestinglab.com]
The most common symptoms of mycotoxins exposure include diarrhoea, headaches, skin irritation and fatigue and in worst cases also impaired or altered immune function. [blackmould.me.uk]
Rheumatoid Arthritis Scleroderma Asthma COPD Chronic Sinusitis Chronic Bronchitis Dysautonomia Autism Parkinson’s Mental Illness Alzheimer’s Chronic Lyme Disease Symptoms of Mycotoxicosis: Headaches, migraines, brain lesions Chronic fatigue, exhaustion Irritable [spoonielife.wordpress.com]
- Ataxia
Symptoms and signs Skin Local pain Pruritus Skin redness Vesicle s Skin necrosis and sloughing Respiratory Nose and throat pain Nasal discharge Itch ing and sneezing Cough Dyspnea Wheezing Chest Pain Hemoptysis Severe systemic Prostration Weakness Ataxia [fpnotebook.com]
Systemic symptoms can develop with all routes of exposure (especially inhalation) and might include weakness, ataxia, hypotension, coagulopathy, and death (1). [emergency.cdc.gov]
Systemic symptoms can develop with all routes of exposure and might include weakness, ataxia, hypotension, coagulopathy, and death. In airborne form, Trichothecene mycotoxins can be dispersed through the air or mixed in food or beverages. [globalsecurity.org]
Once the mycotoxins enter the system, symptoms include weakness, prostration, dizziness, ataxia, loss of coordination, and in fatal cases, tachycardia, hypothermia, and hypotension. Death may occur in minutes, hours, or days. Diagnosis. [mycotoxintestinglab.com]
Irrespective of the route of exposure, when the toxin reaches the rest of the body's systems, it may cause weakness, prostration, dizziness, ataxia and loss of coordination. [firehouse.com]
- Burning Sensation
[…] mouth - burning eyes - burning throat - burning lungs C - cancer - candida, systemic - Chronic Candidiasis FAQ - see Dr. [o2wizard.com]
Other symptoms may include respiratory difficulty, rash, burning sensations in the nose and mouth, and gastrointestinal disorders. Serious toxicity may result in impaired speech, seizures, stroke, and paralysis. [spoonielife.wordpress.com]
Workup
Microbiology
- Fusarium
Definition (MSH) A potent mycotoxin produced in feedstuffs by several species of the genus FUSARIUM. It elicits a severe inflammatory reaction in animals and has teratogenic effects. [fpnotebook.com]
Deoxynivalenol Toxin produced by Fusarium molds which causes livestock feed refusal, vomiting and interferes with growth and development. [vicam.com]
Codes of practice – fusarium and ochratoxin A We have developed two specific codes of practice for England, Wales and Northern Ireland to reduce fusarium and ochratoxin A mycotoxins in cereals, and a leaflet which summarises these codes of practice for [food.gov.uk]
However, commercially produced poultry in modern production units can still be exposed to considerable levels of Fusarium spp. mycotoxins in feed due to the heavy reliance on cereal grains. [wattagnet.com]
Author information 1 Applied Mycology Unit, Food Technology Department, University of Lleida, XaRTA-UTPV, Lleida, Spain. [email protected] Abstract HT-2 toxin (HT2) and T-2 toxin (T2) are mycotoxins produced in several cereals by species of Fusarium [ncbi.nlm.nih.gov]
Treatment
Treatment The most effective treatment is removal of the source of toxins. Addition of antifungal feed preservatives is also helpful. Increasing protein level in the feed until mortality reduces may also be beneficial. [thepoultrysite.com]
However, immediate treatment is critical in preventing continued degeneration, anaphylaxis, cancer, organ failure, and death. Treatment may provide some mild symptom relief, which most people with mycotoxicosis are ever so desperate for. [spoonielife.wordpress.com]
Treatment. Again, exposure can be prevented with a gas mask and protective chemical gear. All treatment is supportive because no antitoxins or antifungals are presently available. [8,16,17] (8.) [mycotoxintestinglab.com]
Treatment for victims of ricin poisoning remains supportive. [firehouse.com]
[…] triglycerides unusual variations - chronic fatigue syndrome (CFS) - chronic sinus infections - coated tongue - coccidioidomycosis - colds, recurrent - constipation - cough, dry hacking - coughing up blood - cryptococcosis D - dandruff resistant to usual treatments [o2wizard.com]
Etiology
The case can be confirmed if laboratory testing was not performed because either a predominant amount of clinical and nonspecific laboratory evidence of a particular chemical was present or the etiology of the agent is known with 100% certainty. [emergency.cdc.gov]
Epidemiology
Macmahon, B. (1994) The epidemiological evidence on the carcinogenicity of Beryllium to Humans, J. [books.google.com]
Probable : A clinically compatible case in which a high index of suspicion (credible threat or patient history regarding location and time) exists for trichothecene mycotoxins exposure, or an epidemiologic link exists between this case and a laboratory-confirmed [emergency.cdc.gov]
Pathophysiology
Pathophysiology Agent Trichothecene Mycotoxins Produced by filamentous fungi (molds) Inactivation Extremely stable in heat and UV light Destruction requires heating 1500 F for 30 minutes Brief exposure to sodium Hypochlorite inactivates Transmission Used [fpnotebook.com]
Prevention
Prevention Mycotoxicoses may be prevented by careful choice of feed raw materials, reduction in water content of the raw materials and hygienic storage. Antimycotic feed additives may also be used but may not deal with toxins already formed. [thepoultrysite.com]
Prevention No Vaccine or antitoxin available Decontamination Images: Related links to external sites (from Bing) Ontology: T-2 Toxin (C0039185) Definition (CSP) potent mycotoxin produced in feedstuffs by some Fusarium species. [fpnotebook.com]
Again, exposure can be prevented with a gas mask and protective chemical gear. All treatment is supportive because no antitoxins or antifungals are presently available. [8,16,17] (8.) [mycotoxintestinglab.com]
Experimental vaccines are also under development for prevention of botulinum intoxication. Staphylococcal enterotoxin B (SEB) is a common cause of food poisoning. [firehouse.com]
However, immediate treatment is critical in preventing continued degeneration, anaphylaxis, cancer, organ failure, and death. Treatment may provide some mild symptom relief, which most people with mycotoxicosis are ever so desperate for. [spoonielife.wordpress.com]