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Mydriasis


Presentation

  • This unique presentation of pharmacological mydriasis reinforces the importance of supplement histories in our military populations for various health presentations.[ncbi.nlm.nih.gov]
  • We suggest that the transitory mydriasis previously present could be considered as an unusual form of migrainous aura. A possible pathogenetic mechanism is proposed.[ncbi.nlm.nih.gov]
  • BACKGROUND: Approximately 50% of patients with Fisher's syndrome show involvement of the pupillomotor fibers and present with mydriasis and light-near dissociation.[ncbi.nlm.nih.gov]
  • PURPOSE: To present 4 cases of unilateral mydriasis associated with orthognathic surgery and to review the differential diagnosis and management related to this condition.[ncbi.nlm.nih.gov]
  • Proper Lewy bodies were also present. Differences seemed to prevail vs the Shy-Drager syndrome.[ncbi.nlm.nih.gov]
Hypersalivation
  • Common signs of neurotoxic envenoming included bilateral ptosis, persistently dilated pupils, limb weakness, breathlessness, hypersalivation, dysphonia and dysphagia.[ncbi.nlm.nih.gov]
Cardiomegaly
  • The main features were: mydriasis, cardiac arrhythmia, cardiomegaly, hypohidrosis, respiratory failure, and muscular weakness. METHODS: Pupillometry, evaporimetry, and isokinetic power measurements were carried out.[ncbi.nlm.nih.gov]
Small Hand
  • The purpose of this study was to determine whether a small, hand-held, mydriasis-free, full-field flicker electroretinographic (ERGs) device called RETeval can be used to screen for DR.[ncbi.nlm.nih.gov]
Transient Blindness
  • They include transient blindness (amaurosis), ophthalmoplegia, ptosis, mydriasis and diplopia. These events may occur following the intravascular administration of anaesthetic solution and are distressing to both patient and operator alike.[ncbi.nlm.nih.gov]
Unilateral Ptosis
  • Abstract We report a patient who has a tremor and unilateral ptosis and mydriasis without extraocular muscle paresis from an intra-axial lesion demonstrated on neuroimaging.[ncbi.nlm.nih.gov]
Limb Weakness
  • Common signs of neurotoxic envenoming included bilateral ptosis, persistently dilated pupils, limb weakness, breathlessness, hypersalivation, dysphonia and dysphagia.[ncbi.nlm.nih.gov]
  • Unilateral miosis or Horner’s syndrome often raises the suspicion of carotid artery dissection, especially if painful and accompanied by contralateral limb weakness. 1 In contrast, isolated mydriasis has rarely been reported in connection with compromised[neurology.org]
  • There was no limb weakness or ataxia, but the patient's deep tendon reflexes were decreased in the upper extremities and absent in the lower extremities. His plantar responses were flexor. His sensations of touch, pain, and vibration were normal.[karger.com]

Workup

  • But when a patient has isolated, episodic unilateral mydriasis and migraine, such a patient may be reassured and further workup undertaken only if symptoms worsen or change.[ncbi.nlm.nih.gov]
Pneumoperitoneum
  • Induction of pneumoperitoneum for laparoscopy may be particularly hazardous in a patient with a phaeochromocytoma.[ncbi.nlm.nih.gov]

Treatment

  • Cases were randomly assigned to 1 of 6 groups receiving the following treatments: (1) diclofenac (0.1%); (2) pranoprofen (0.1%); (3) control, physiological normal saline solution; (4) diclofenac (0.1%) and epinephrine; (5) pranoprofen (0.1%) and epinephrine[ncbi.nlm.nih.gov]
  • Treatment : Treatment is oriented towards reducing the symptoms and protecting the eyes. If timely treatment is given mydriasis can be cured. Drugs like murocol 2, phenylephrine and scopolamine are given for treating the condition of dilated pupils.[diseasespictures.com]
  • Treatment included bolus doses of esmolol, nicardipine and urapidil (an alpha 1 adrenergic antagonist) by constant intravenous infusion and mechanical ventilation. Postoperative cerebral CT scan was normal.[ncbi.nlm.nih.gov]
  • The patient showed bilateral mydriasis and a missing light reflex 8 hours after changing sedation from intravenous treatment with midazolam and esketamine to volatile administration of isoflurane.[ncbi.nlm.nih.gov]

Prognosis

  • BACKGROUND: Pupils' abnormalities are associated to bad prognosis in traumatic brain injury.[ncbi.nlm.nih.gov]
  • Patients with episodes similar in characteristics to the ones described in this survey appear to have a benign neurologic prognosis, and do not require further neurodiagnostic studies.[ncbi.nlm.nih.gov]
  • Mydriasis Prognosis The condition has a positive outcome which actually depends on the management of the disease and its timely treatment. If cured in time, the condition can be only temporary.[hxbenefit.com]
  • Prognosis Prognosis is excellent for pharmacologic dilation of the pupil, and the condition should completely resolve with removal of the precipitating agent. Resolution of dilation depends on the different agents' half life.[eyewiki.org]

Etiology

  • CONCLUSION: In the absence of neurologic deficits, clinical history should search for a toxic or pharmacologic etiology of abnormal mydriasis.[ncbi.nlm.nih.gov]
  • The specific clinical context (cancer) reported here may have led to the misinterpretation of the etiology of mydriasis.[ncbi.nlm.nih.gov]
  • They remain a diagnostic challenge for specialists as they may be due to several etiological factors. In the absence of other accompanying symptoms, anisocorias are usually due to benign processes.[ncbi.nlm.nih.gov]
  • Depending on the etiology of your mydriasis, other symptoms may also present.[belmarrahealth.com]

Epidemiology

  • SUBJECTS, MATERIAL AND METHODS: We describe the epidemiological and clinical characteristics of patients with BEM, assessed in a neuro-ophthalmology unit in a tertiary hospital.[ncbi.nlm.nih.gov]
  • The quality of the SIDIAP data has been previously documented, and the database has been widely used to study the epidemiology of a number of health outcomes [ 16, 17 ].[journals.plos.org]
Sex distribution
Age distribution

Pathophysiology

  • The postulated pathophysiologic aetiology is a partial third nerve palsy with the pupillary fibres for light and accommodation-convergence affected and motor fibres spared. The mechanism responsible for the postulated lesion is speculative.[ncbi.nlm.nih.gov]
  • Benign episodic mydriasis (BEM) is an isolated cause of intermittent pupil asymmetry, in which the pathophysiology is still not fully understood, and is predominant in young women with migraine.[ncbi.nlm.nih.gov]
  • Changes in pupil size are governed by pupillary sphincter (parasympathetic) and the pupillary dilator muscle (sympathetic) tone in response to ambient light, adrenergic and cholinergic tone, and local pharmacologic or pathophysiologic conditions.[ajnr.org]
  • Pathophysiology Anticholinergic mydriasis occurs via blockade of parasympathetic muscarinic acetylcholine receptors on the iris sphincter muscle.[eyewiki.org]

Prevention

  • The pupil constricts in bright light exposure to prevent and protect the eye from the aberration of light ray and attain an expected acuity in bright environment. Leave a Reply[healthosphere.com]
  • Early detection and treatment could prevent vision loss. See an eye care professional right away if you have a sudden change in vision, if everything looks dim, or if you see flashes of light.[icdlist.com]
  • Recently, a new combination of phenylephrine and ketorolac (Omidria ) has been approved by United States Food and Drug Administration for use during cataract surgery to maintain intraoperative mydriasis, prevent miosis, and reduce postoperative pain and[doi.org]

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