Presentation
MF was present in four athletes (range 1-8 g) and not present in five athletes. MF was located near the insertion points of the right ventricular free wall on the left ventricle in three athletes and in the epicardial lateral wall in one athlete. [ncbi.nlm.nih.gov]
Entire Body System
- Congestive Heart Failure
We describe a 27-year-old woman with a 6 year history of severe polymyositis and persistent elevation of creatine phosphokinase-MB isoenzyme who suddenly developed congestive heart failure and bradycardia-tachycardia syndrome. [ncbi.nlm.nih.gov]
Clinically, may be silent or producing stabile angina pectoralis leading to congestive heart failure. [pathologyatlas.ro]
- Swelling
[…] fibrosis (EMF) has an insidious onset, and symptoms relate to the specific chambers and valves where the disease is most extensive, including the following: When right ventricular involvement or tricuspid regurgitation predominates, lower extremity swelling [emedicine.medscape.com]
Its symptoms include chest pain, some abdominal swelling, nausea and fatigue. This usually indicates an array of heart problems, with progressive heart failure being a prime example. [wisegeekhealth.com]
- Myxedema
A case of myxedema with diffuse myocardial fibrosis proven by endomyocardial biopsy. [medical-dictionary.thefreedictionary.com]
- Weakness
[…] agonists suggest that some other agents in this class, such as lisuride and terguride, may not have similar consequences. 15 The finding of a significantly greater mitral tenting area in the non-ergot group than in the control group could be evidence of a weak [doi.org]
Cardiovascular
- Heart Disease
Abstract Myocardial fibrosis is one of the most common histopathological lesions found in chronic heart diseases. Progressive development of myocardial fibrosis will cause heart failure, an extremely debilitating and life threatening condition. [ncbi.nlm.nih.gov]
These include four anatomical and clinical entities : Chronic ischemic heart disease stabile angina pectoralis Acute ischemic heart disease unstabile angina pectoralis myocardium infarct sudden death Etiology : coronary artery atherosclerosis (90 %), [pathologyatlas.ro]
- Tachycardia
We describe a 27-year-old woman with a 6 year history of severe polymyositis and persistent elevation of creatine phosphokinase-MB isoenzyme who suddenly developed congestive heart failure and bradycardia-tachycardia syndrome. [ncbi.nlm.nih.gov]
With these studies, it is possible to determine the number of arrhythmic morphologies, the ease of tachycardia induction, tolerance to tachycardic events, and the capacity for the tachycardia to develop into lethal arrhythmias. [af-ablation.org]
- Cardiomegaly
A tachycardia of 145 beats per min and radiological evidence of cardiomegaly indicated involvement of the heart, but an ECG failed to show signs of myocarditis or cardiac hypertrophy. [ncbi.nlm.nih.gov]
Therefore, most of these cases may be a sequela of myocarditis, and more correctly termed post-myocarditic cardiomegaly. [link.springer.com]
[…] catheterization 心[臓]カテーテル法 cardiac cycle 心[臓]周期 cardiac death心臓死 cardiac index (CI)心係数 cardiac muscle (= myocardium)心筋 cardiac output 心拍出量 cardiac rupture心[臓]破裂 cardiac silhouette心陰影 cardiac standstill心静止 cardiac tamponade 心タンポナーデ cardiogenic shock 心原性ショック cardiomegaly [tokyo-med.ac.jp]
Psychiatrical
- Suggestibility
It is suggested that, when drug induced pneumonitis is noted, careful screening of left ventricular function should be performed in order to diagnose myocardial fibrosis and subsequent cardiac failure. [ncbi.nlm.nih.gov]
Abstract Limited evidence suggests that myocardial fibrosis might be associated with dietary cardiovascular risk factors. [vuir.vu.edu.au]
Neurologic
- Stroke
Footnotes This work was supported by the Heart and Stroke Foundation of Canada and Quebec, Canadian Institutes of Health Research, and “Fonds de la Recherche de l'Institut de Cardiologie de Montréal” (FRICM). M. [doi.org]
If required, a biopsy of the heart muscle may be ordered Some potential complications of Restrictive Cardiomyopathy include aberrant heartbeats (arrhythmia), sudden cardiac arrest, development of blood clot, stroke, and fluid build-up in the tissues and [dovemed.com]
Phase-contrast velocity images in the ascending aorta were obtained to measure stroke volume and rule out significant aortic insufficiency. [omicsonline.org]
(1)拍動 (2)卒中、発作〈脳の〉 stroke index (SI)一回拍出係数 stroke volume (SV)一回拍出量 stunned myocardium気絶心筋 subacute bacterial endocarditis (SBE)亜急性細菌性心内膜炎 subclavian artery鎖骨下動脈 subendocardial心内膜下 【形】 sudden death急死〈頓死〉、突然死 superior vena cava (SVC)上大静脈 supraventricular [tokyo-med.ac.jp]
Workup
QT, RR, ST Intervals
- ST Elevation
Impact of primary coronary angioplasty delay on myocardial salvage, infarct size, and microvascular damage in patients with ST-segment elevation myocardial infarction: insight from cardiovascular magnetic resonance. J. Am. Coll. [nature.com]
Treatment
Furthermore, the level of NT-proBNP was reduced significantly after TEA plus OMT treatment. Consistent with echocardiography parameters, the LVEF measured by CMR also was increased markedly. [ncbi.nlm.nih.gov]
The no-intent-to-treat group was randomized into 2 subgroups: group ND-NT (no dysfunction-no treatment), in which patients received all necessary, guideline-based treatment for their condition but no treatment for cardiomyopathy or heart failure; and [neurologyadvisor.com]
A longer steroid treatment duration was found to be associated with a lower age‐related increase in myocardial fibrosis burden. [musculardystrophynews.com]
Prognosis
These have yielded new insights into disease prognosis and response to treatment. [heart.bmj.com]
CMR is superior to conventional echocardiography for the detection of myocardial fibrosis in desmin-related cardiomyopathy, which may be useful to detect early cardiac involvement and predict the patient prognosis. [ncbi.nlm.nih.gov]
Etiology
Cardiomyopathies/therapy* Death, Sudden, Cardiac/etiology Death, Sudden, Cardiac/prevention & control Defibrillators, Implantable Electric Countershock/instrumentation Electrocardiography Fibrosis Heart Rate* Humans Magnetic Resonance Imaging Myocardium [ncbi.nlm.nih.gov]
In a novel study Assomull et al. [ 40 ] examined patients with new-onset heart failure of unknown etiology. They examined the diagnostic accuracy of LGE to determine the etiology of heart failure in this patient collective. [omicsonline.org]
Epidemiology
Original Research Association of Cardiovascular Risk Factors and Myocardial Fibrosis With Early Cardiac Dysfunction in Type 1 Diabetes: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study, Bharath [care.diabetesjournals.org]
DESIGN AND METHODS: Participants with type 1 diabetes aged 13-39 years without a known history of cardiovascular disease (CVD) ( n = 1,441) were recruited into the Diabetes Control and Complications Trial (1983-1993) and subsequently followed in the Epidemiology [ncbi.nlm.nih.gov]
Chagas disease in Latin America: an epidemiological update based on 2010 estimates. WHO: Wkly Epidemiol Rec 2015; 90:33-43. [ Links ] 2. Büllow, T. von. ¿Existe en Costa Rica la tripanosomiasis humana? Rev Méd Costa Rica 1941; 4: 410-4. [ Links ] 3. [scielo.sa.cr]
Pathophysiology
There are multiple types of myocardial fibrosis that occur in response to different pathophysiologic stimuli. Recent advances in imaging technology have made detection and quantification of the types of myocardial fibrosis possible. [ncbi.nlm.nih.gov]
Myocardial fibrosis is the pathophysiological hallmark of failing heart. [kclpure.kcl.ac.uk]
Prevention
Inhibition of T-cell factor (TCF)/β-catenin-mediated transcription with ICG-001 or genetic loss of β-catenin also prevented TGF-β-induced myofibroblasts formation. [ncbi.nlm.nih.gov]
The bottom line is that this shows for the first time that cardiac fibrosis is preventable.” [chemdiv.com]