Presentation
A case of sudden death of a previously asymptomatic young man, having a definitive autoptic diagnosis of dilated cardiomyopathy with endomyoelastofibrosis, is presented. [ncbi.nlm.nih.gov]
The majority of intracardiac IMTs occur in pediatric patients, with approximately half presenting in children aged 1 In addition to cardiac signs and symptoms, the clinical presentation of IMTs may also include constitutional signs such as fever, anemia [pediatrics.aappublications.org]
The mean age of presentation is 46 years and they are twice as common in males than in females. We present the case of a patient with a primary pericardial mesothelioma presenting with ST-elevation myocardial infarction. [elsevier.pt]
Pericardial tamponade is by far the most frequent manifestation; however the patient presentation is a based on the area of cardiac involvement (3, 4). [ctsnet.org]
Patients present with cardiac atrophy, which resolves after disease treatment. [escardio.org]
Entire Body System
- Pain
Angina was defined as oppressive precordial pain associated with electrocardiographic changes occurring at admission or follow-up, excluding inducible angina during risk stratification tests. [revespcardiol.org]
Chest pain or tightness in the chest. More general symptoms mimic the symptoms of endocarditis and may also include: Fever or cough. Involuntary weight loss. Joint pain. [hopkinsmedicine.org]
Clinical Presentation Cardiac and non-cardiac manifestations Location and size of tumor the major determinants of specific signs and symptoms Signs & symptoms similar to all form of heart disease: Chest pain Syncope Heart failure Murmurs Arrhythmias Conduction [slideshare.net]
The inflammation may cause a fever, and the patient may have joint pain or not feel well. What causes cardiac tumors? A small percentage of patients with cardiac tumors have a family history of the condition. [my.clevelandclinic.org]
Clinical History A 35 year-old woman with no prior medical history presented to an outside hospital with pleuritic chest pain. A non-gated chest CTA scan showed a cardiac mass and pericardial pleural effusions. [massgeneral.org]
- Inflammation
Biopsies were analyzed for TNF-alpha, C5b-9, markers of inflammation and for viral genome. [ncbi.nlm.nih.gov]
Conclusions: These data suggest that Losartan may mitigate tumor-induced myocardial dysfunction and inflammation. [epublications.marquette.edu]
The recent recognition that inflammation is a risk factor and prognostic factor for heart disease has laid ground for preventive medicine and even anti-infective strategies in prevention and treatment of heart failure. معاينة هذا الكتاب » [books.google.com]
The inflammation may cause a fever, and the patient may have joint pain or not feel well. What causes cardiac tumors? A small percentage of patients with cardiac tumors have a family history of the condition. [my.clevelandclinic.org]
- Surgical Procedure
Treatment Removing a noncancerous primary heart tumor surgically is an option and results in the elimination of the tumor. Other surgical procedures may be possible to assist heart function for larger noncancerous primary heart tumors. [hopkinsmedicine.org]
Benign heart tumors occasionally manifest in critical areas which may complicate the surgical procedure, or prolong the time of surgery. [symbiosisonlinepublishing.com]
- Swelling
Presenting complaint was swelling of the face. [wagwalking.com]
Swelling of the legs, ankles or abdomen. Causes Causes of tumors vary, but generally are thought to be the result of abnormal regulation of cell division. [hopkinsmedicine.org]
Gastrointestinal
- Diarrhea
Malignant Carcinoid Tumors that elaborate vasoactive amines (eg serotonin), kinins, indoles responsible for diarrhea, flushing, labile BP Gastrointestinal carcinoids Almost exclusively in the right side Occur only with hepatic metastases substance [slideshare.net]
There was no history of diarrhea, bloody stools, or sick contacts. Her medical history was otherwise unremarkable. Growth parameters were appropriate for age. [pediatrics.aappublications.org]
- Constipation
Hypothyroidism Clinical Findings: Systemic signs and symptoms Weight gain, weakness, lethargy, fatigue, depression Constipation, cold intolerance, dry skin, coarse hair Menstrual disorders, impotence or decreased libido 60. [slideshare.net]
Cardiovascular
- Left Ventricular Dysfunction
Discussion Left ventricular thrombus formation is a frequent complication in the patient with history of anterior wall myocardial infarct and in those patients with systolic left ventricular dysfunction. [omicsonline.org]
Excessive tumor necrosis factor activation after infarction contributes to susceptibility of myocardial rupture and left ventricular dysfunction. Circulation. 2004;110:3221-8. Medline 15. Saraste A, Voipio-Pulkki LM, Laine P, Nieminem MS, Pulkki K. [revespcardiol.org]
Neurologic
- Stroke
Benign neoplasm of the heart increases the risk of first ischemic stroke: a population-based cohort study. Int J Stroke. 2015 Feb. 10 (2):202-6. [Medline]. Salcedo EE, Cohen GI, White RD, Davison MB. Cardiac tumors: diagnosis and management. [emedicine.medscape.com]
Al Ali A, A Shawaf H, Al Khalaf Y (2011) Stroke caused by left ventricular myxoma. J Am CollCardiol 57: e11. [omicsonline.org]
Diabetes Mellitus Increased incidence of CAD most common cause of death in adults with DM Two types of vascular disease Macrovascular Atherosclerosis & arteriosclerosis - CAD Cerebral circulation TIA, stroke Lower limb circulation claudication, [slideshare.net]
Workup
This case demonstrates the complimentary information offered by the multimodality workup of a rare myocardial tumor. [massgeneral.org]
On further workup, a transthoracic echocardiogram (TTE) showed a large mass within the right atrium, which extended into the right ventricle ( Figure 1 ). [ctsnet.org]
Other possibilities include cardiac myxoma or other cardiac tumors Cardiovascular magnetic resonance (CMR) has become a mainstream imaging modality in the workup of intracardiac masses. [omicsonline.org]
X-Ray
- Pericardial Effusion
A moderate pericardial effusion with peripheral enhancement is demonstrated. Figure 3. Delayed-enhanced inversion-recovery short-axis MR image demonstrates enhancing visceral and parietal pericardium separated by pericardial effusion. [massgeneral.org]
Effusion MI with left ventricular failure CHD with highest association of pericardial abnormalities ASD Site of pulmonic stenosis Valvular [learningradiology.com]
The echocardiogram showed a large pericardial effusion with diffuse thickening of the myocardium. [elsevier.pt]
effusion or tamponade 6. [slideshare.net]
Mild bradycardia, diastolic hypertension, low apical impulse, an increase in low-density lipoprotein and cholesterol and increased frequency of pericardial effusions are the main findings. [escardio.org]
Treatment
Patients received conventional treatment of heart failure and, in a few cases, additional treatment with interferon beta(1b) (virus positive) or prednisolone (inflammatory DCM). [ncbi.nlm.nih.gov]
The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. [books.google.com]
Currently, cryotherapy is mainly used in the treatment of lung, digestive, prostatic lesions and tumors, and in certain tachyarrhythmias In this article, we used cryotherapy in the treatment of benign heart tumors localized in critical areas to destruct [symbiosisonlinepublishing.com]
Losartan treatment prevented tumor-induced loss of muscle mass and in vitro c26 cell proliferation, decreased tumor weight, and attenuated myocardial expression of interleukin-6. [epublications.marquette.edu]
Prognosis
In patients with dilated cardiomyopathy, elevated plasma levels of tumor necrosis factor-alpha are associated with poor prognosis. [ncbi.nlm.nih.gov]
The malignant tumors of the heart have a worse prognosis. [en.wikipedia.org]
Prognosis in patients with heart tumors Nowadays, at the clinic "Herzliya Medical Center", the prognosis of cardiac cancer and tumors is quite favorable in most cases. [hmcisrael.com]
Patients with a resectable tumor usually have a good prognosis, but prognosis of the asymptomatic patient with an unresectable tumor is unpredictable and may have a poor prognosis because of ventricular tachycardia, sudden death, or local progression [scmr.org]
Etiology
Etiology The precise etiology of benign cardiac tumors is unknown. [emedicine.medscape.com]
Although echocardiography can be helpful to differentiate the etiology of the lesion, 16 histologic examination remains the gold standard for confirmation of the diagnosis. [pediatrics.aappublications.org]
Patient was started on anticoagulation with heparin with suspicion of possible apical thrombus however possibility of different etiology of cardiac mass was not entirely excluded. [omicsonline.org]
Epidemiology
Epidemiology Primary cardiac tumors have an estimated autopsy prevalence of 0.001-0.03% 2. [radiopaedia.org]
Epidemiology United States Benign cardiac tumors are extremely rare. Of all primary cardiac tumors, 75% are histologically benign. [emedicine.medscape.com]
Mesothelioma epidemiology, carcinogenesis, and pathogenesis. Curr Treat Options Oncol, 9 (2008), pp. 147-157 [16] T. Butz, L. Faber, C. Langer, et al. [elsevier.pt]
Pathophysiology
Pathophysiology Myxomas arise usually from the endocardium and range in size from 1-20 cm. [emedicine.medscape.com]
[…] predictor of ischemic events, similar to high CRP concentrations, it may reflect a concomitant exacerbated inflammatory state and positively correlate with other markers (IL-6, CRP and sICAM-1), all of which are involved in the inflammatory cascade and that pathophysiologically [revespcardiol.org]
Prevention
The recent recognition that inflammation is a risk factor and prognostic factor for heart disease has laid ground for preventive medicine and even anti-infective strategies in prevention and treatment of heart failure. معاينة هذا الكتاب » [books.google.com]
In the present study, we investigated whether an angiotensin (AT) 1-receptor antagonist could prevent the development of tumor-associated myocardial dysfunction. [epublications.marquette.edu]
Prevention By avoiding things that cause cancer, the risk of tumors can be greatly reduced, if not prevented. Don’t smoke or use tobacco products. Reduce, limit or otherwise moderate heavy drinking, excessive exposure to the sun and radiation. [hopkinsmedicine.org]
Lyme disease was first widely recognized in 1975 in […] September 20, 2018 According to a recent report published by the Centers for Disease Control and Prevention in the United States, insect-borne diseases in the US tripled during the […] [www4ro.dr-rath-foundation.org]
The thromboembolic complications prevention and pain management are also important. [hmcisrael.com]