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Myocardial Tumor

Neoplasm of Myocardium


Presentation

  • A case of sudden death of a previously asymptomatic young man, having a definitive autoptic diagnosis of dilated cardiomyopathy with endomyoelastofibrosis, is presented.[ncbi.nlm.nih.gov]
  • However, TNFα values were not analyzed later, unlike in the present study.[revespcardiol.org]
  • Abstract Objectives According to previous studies, the aim of the presented work is to investigate the possible association between the codon 72 polymorphism (Pro72Arg, rs1042522) of the tumor suppressor gene (p53) with acute myocardial infarction (AMI[jocms.org]
  • Here, we present a case of concomitant acute myocardial infarction and bleeding tumor in the transverse colon, and share our experience of successfully balancing anticoagulation therapy and hemostasis.[dovepress.com]
  • In the present study, we investigated whether an angiotensin (AT) 1-receptor antagonist could prevent the development of tumor-associated myocardial dysfunction.[epublications.marquette.edu]
Inflammation
  • Biopsies were analyzed for TNF-alpha, C5b-9, markers of inflammation and for viral genome.[ncbi.nlm.nih.gov]
  • Conclusions: These data suggest that Losartan may mitigate tumor-induced myocardial dysfunction and inflammation.[epublications.marquette.edu]
  • Inflammation. Interleukins. Tumor necrosis factor alpha.[revespcardiol.org]
  • The inflammation may cause a fever, and the patient may have joint pain or not feel well. What causes cardiac tumors? A small percentage of patients with cardiac tumors have a family history of the condition.[my.clevelandclinic.org]
Asymptomatic
  • A case of sudden death of a previously asymptomatic young man, having a definitive autoptic diagnosis of dilated cardiomyopathy with endomyoelastofibrosis, is presented.[ncbi.nlm.nih.gov]
  • Often cardiac haemangioma are asymptomatic and discovered incidentally during cardiac surgery or on autopsy.[scmr.org]
  • Clinical presentation ranged from asymptomatic patients to cardiac arrest. 111 In Octreotide SPECT•CT provides comprehensive characterization and localization of carcinoid metastases, especially in locations like the heart where accurate localization[usa.healthcare.siemens.com]
Hunting
  • Stoica SC, Mitchell IM, Foreman J, Hunt CJ, Wallwork J, Large SR. Atrial transplantation for recurrent cardiac sarcoma. J Heart Lung Transplant 2001; 20: 1220–1223.[link.springer.com]
Left Ventricular Dysfunction
  • Discussion Left ventricular thrombus formation is a frequent complication in the patient with history of anterior wall myocardial infarct and in those patients with systolic left ventricular dysfunction.[omicsonline.org]
  • Excessive tumor necrosis factor activation after infarction contributes to susceptibility of myocardial rupture and left ventricular dysfunction. Circulation. 2004;110:3221-8. Medline 15. Saraste A, Voipio-Pulkki LM, Laine P, Nieminem MS, Pulkki K.[revespcardiol.org]
Pulsus Paradoxus
Suggestibility
  • Conclusions: These data suggest that Losartan may mitigate tumor-induced myocardial dysfunction and inflammation.[epublications.marquette.edu]
  • […] distribution for the Pro72Arg variant of the p53 gene in AMI smokers patients (PP: n 20, 51.3%; RP: n 1, 2.6%; RR: n 18, 46.2%) and controls (PP: n 14, 82.4%; RP: n 2, 11.8%; RR: n 1, 5.9%) was significantly different (p 0.009).Conclusion These findings suggest[jocms.org]
  • There is a small focal area of increased uptake in the thorax that corresponds to the left ventricular apex (white arrows), which is suggestive of focal myocardial metastases. The myocardial lesion measured 0.9 cm in size.[usa.healthcare.siemens.com]
  • Demonstration of elevated serum dopamine is a sign of possible malignant transformation, suggesting tumor in an extra-adrenal site. Definitive treatment requires tumor removal (7).[escardio.org]
  • This information, together with the lack of predictive value of TNFα concentrations at admission in the patients who died, suggests that such an early sample is unlikely to be of prognostic use.[revespcardiol.org]

Workup

  • This case demonstrates the complimentary information offered by the multimodality workup of a rare myocardial tumor.[massgeneral.org]
  • On further workup, a transthoracic echocardiogram (TTE) showed a large mass within the right atrium, which extended into the right ventricle ( Figure 1 ).[ctsnet.org]
  • Other possibilities include cardiac myxoma or other cardiac tumors Cardiovascular magnetic resonance (CMR) has become a mainstream imaging modality in the workup of intracardiac masses.[omicsonline.org]
ST Elevation
  • DOI 10.1007/s00134-015-3749-6 Wei-Ting Chang Acute ruptured mycotic aneurysm mimicking Nan-Haw Chow Yi-Shan Tsai myocardial tumor with ST elevation myocardial Chih-Chan Lin infarction infection.[deepdyve.com]
  • We present the case of a patient with a primary pericardial mesothelioma presenting with ST-elevation myocardial infarction.[elsevier.pt]

Treatment

  • Patients received conventional treatment of heart failure and, in a few cases, additional treatment with interferon beta(1b) (virus positive) or prednisolone (inflammatory DCM).[ncbi.nlm.nih.gov]
  • The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure.[books.google.com]
  • Losartan treatment prevented tumor-induced loss of muscle mass and in vitro c26 cell proliferation, decreased tumor weight, and attenuated myocardial expression of interleukin-6.[epublications.marquette.edu]
  • […] equally to this work Abstract: Acute myocardial infarction complicated by bleeding colon tumor is problematic with regard to management, and appropriate balance of antiplatelet or anticoagulation therapy and hemostasis or surgery is crucial for effective treatment[dovepress.com]

Prognosis

  • In patients with dilated cardiomyopathy, elevated plasma levels of tumor necrosis factor-alpha are associated with poor prognosis.[ncbi.nlm.nih.gov]
  • Prognosis. Inflammation. Interleukins. Tumor necrosis factor alpha.[revespcardiol.org]
  • The malignant tumors of the heart have a worse prognosis.[en.wikipedia.org]
  • Prognosis in patients with heart tumors Nowadays, at the clinic "Herzliya Medical Center", the prognosis of cardiac cancer and tumors is quite favorable in most cases.[hmcisrael.com]

Etiology

  • Etiology The precise etiology of benign cardiac tumors is unknown.[emedicine.medscape.com]
  • Although echocardiography can be helpful to differentiate the etiology of the lesion, 16 histologic examination remains the gold standard for confirmation of the diagnosis.[pediatrics.aappublications.org]
  • Patient was started on anticoagulation with heparin with suspicion of possible apical thrombus however possibility of different etiology of cardiac mass was not entirely excluded.[omicsonline.org]

Epidemiology

  • Epidemiology Primary cardiac tumors have an estimated autopsy prevalence of 0.001-0.03% 2.[radiopaedia.org]
  • Epidemiology United States Benign cardiac tumors are extremely rare. Of all primary cardiac tumors, 75% are histologically benign.[emedicine.medscape.com]
  • Mesothelioma epidemiology, carcinogenesis, and pathogenesis. Curr Treat Options Oncol, 9 (2008), pp. 147-157 [16] T. Butz, L. Faber, C. Langer, et al.[elsevier.pt]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Myxomas arise usually from the endocardium and range in size from 1-20 cm.[emedicine.medscape.com]
  • […] predictor of ischemic events, similar to high CRP concentrations, it may reflect a concomitant exacerbated inflammatory state and positively correlate with other markers (IL-6, CRP and sICAM-1), all of which are involved in the inflammatory cascade and that pathophysiologically[revespcardiol.org]

Prevention

  • In the present study, we investigated whether an angiotensin (AT) 1-receptor antagonist could prevent the development of tumor-associated myocardial dysfunction.[epublications.marquette.edu]
  • Prevention By avoiding things that cause cancer, the risk of tumors can be greatly reduced, if not prevented. Don’t smoke or use tobacco products. Reduce, limit or otherwise moderate heavy drinking, excessive exposure to the sun and radiation.[hopkinsmedicine.org]
  • Lyme disease was first widely recognized in 1975 in […] September 20, 2018 According to a recent report published by the Centers for Disease Control and Prevention in the United States, insect-borne diseases in the US tripled during the […][www4ro.dr-rath-foundation.org]
  • The thromboembolic complications prevention and pain management are also important.[hmcisrael.com]
  • This may require emergency surgery to prevent sudden death. Cardiac tumor - myxoma; Heart tumor - myxoma Lenihan DJ, Yusuf SW, Shah A. Tumors affecting the cardiovascular system.[medlineplus.gov]

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