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Myoclonic Seizures

Presentation

Ninety-five percent of cases begin in early infancy, typically presenting with irritability, hypertonicity, tonic spasms, visual loss with optic atrophy, and occasionally seizures. [ncbi.nlm.nih.gov]

Juvenile myoclonic epilepsy (JME) is one of the most common generalized epilepsy syndromes and typically presents in the teen years. Clinical Presentation of JME JME accounts for about 25% of all primary generalized epilepsy syndromes. [docneuro.com]

Workup

In this article, the author details the historical aspects, nomenclature, classification, clinical manifestations, pathophysiology, diagnostic workup, differential diagnosis, and management of the various types of myoclonic seizure, paying particular [medlink.com]

Treatment

Abstract Despite the availability of numerous treatment options, the diagnosis and treatment of myoclonic seizures continue to be challenging. [ncbi.nlm.nih.gov]

Prognosis

Abstract Congenital chromosomal abnormality with trisomy 13 is known to be associated with poor life prognosis and lethal. [ncbi.nlm.nih.gov]

With adequate treatment, idiopathic epilepsy syndromes have a good prognosis. [amboss.com]

While JME is a lifelong condition, the prognosis is good due to rare generalized seizures that can, in the majority of patients, be controlled with a single anti-seizure medication. References 1. National Library of Meidcine, JME . [docneuro.com]

This writing is devoted to a discussion of the clinical manifestations, EEC findings, etiology, prognosis and treatment of myoclonic epilepsy of childhood. [pediatrics.aappublications.org]

Juvenile myoclonic epilepsy is distinct from other myoclonic epilepsies, which are often accompanied by other neurologic abnormalities or progressive symptoms and carry a much worse prognosis. [meddean.luc.edu]

Etiology

However, many more treatment options exist today, and the clinician must match the appropriate treatment with the patient's epilepsy syndrome and its underlying etiology. [ncbi.nlm.nih.gov]

The 2 main classification systems of myoclonus are based on etiology and physiology. [medlink.com]

The symptomatic forms are associated with metabolic or structural abnormalities, while the etiology of cryptogenic epilepsies is unknown. [amboss.com]

Epidemiology

/adverse effects* Electroencephalography/statistics & numerical data* Epilepsies, Myoclonic/epidemiology Epilepsies, Myoclonic/genetics* Epilepsy, Frontal Lobe/genetics Epilepsy, Frontal Lobe/physiopathology Epilepsy, Reflex/epidemiology Epilepsy, Reflex [ncbi.nlm.nih.gov]

Epidemiology of epilepsy in Multnomah County, Oregon. Epilepsy, 1975, 8, 115–121. Google Scholar Neidermeyer, E. Compendium of the epilepsies. Springfield, Illinois: Charles C Thomas, 1974. Google Scholar O'Leary, K. D., Kent, R. N., & Kanowitz, J. [link.springer.com]

Pathophysiology

The pathophysiological mechanism of the myoclonic seizures in this uncommon condition was studied. [ncbi.nlm.nih.gov]

Overview Myoclonic seizures are sudden, brief, involuntary, single or multiple jerks that are isolated or rapidly repetitive and of variable topography and pathophysiology. [medlink.com]

Prevention

A program of contingent rest' was then applied on the hospital ward that demonstrated a reduction in myoclonic seizure frequency and the apparent prevention of several grand mal episodes. [ncbi.nlm.nih.gov]

Valproate is used as a first-line agent to prevent the recurrence of febrile seizures and oral/nasal/rectal benzodiazepine is used for any long-lasting seizures. [radiopaedia.org]

The management of triggers such as sleep deprivation and alcohol avoidance is very important to help prevent seizures in addition to taking medication reliably. [epilepsyqueensland.com.au]

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