Clinical Presentation Stargardt disease commonly presents in the second or third decade of life with slowly progressive bilateral visual loss, generally in the range of 20/30 to 20/200.2 The classic fundus appearance of eyes with Stargardt disease is [aao.org]

View abstract Early presentation of pigment dispersion syndrome. Can J Ophthalmol. 2020 02; 55(1):e47-e48. View abstract Placental CpG Methylation of Inflammation, Angiogenic, and Neurotrophic Genes and Retinopathy of Prematurity. [childrenshospital.org]

• Pain

  View abstract Effect of topical anesthesia and age on pain scores during retinopathy of prematurity screening. J Perinatol. 2010 Nov; 30(11):731-5. [childrenshospital.org]

View abstract Strabismus surgery outcomes in the Infant Aphakia Treatment Study (IATS) at age 5 years. J AAPOS. 2016 12; 20(6):501-505. View abstract Treatment of Amblyopia and Amblyopia Risk Factors Based on Current Evidence. [childrenshospital.org]

[…] disease, although research on disease pathophysiology and gene therapy provides hope for future treatment options. [aao.org]

Prognosis and Management Just as Stargardt disease presents with marked phenotypic variability, its impact on visual function is highly variable as well. [aao.org]

[…] retinitis pigmentosa; and they are linked with an increased risk of age-related macular degeneration.3 Although 95 percent of cases of Stargardt disease are caused by mutations in ABCA4, mutations in ELOVL4, BEST1, and PRPH2 genes are also implicated in its etiology [aao.org]

Although further information has been elucidated about the genetics and pathophysiology of Stargardt disease, and improved imaging has led to advances in diagnosis since that time, there is still no effective treatment for the disease. [aao.org]

View abstract Atropine for the Prevention of Myopia Progression in Children: A Report by the American Academy of Ophthalmology. Ophthalmology. 2017 12; 124(12):1857-1866. [childrenshospital.org]