Presentation
Myopia is presented as an example of a complex clinical phenotype where genes and environment interact. [books.google.de]
Vitreous traction is often present. The macula in such cases is may be thickened and microcystic with areas of frank retinoschisis. Of course, vitreous degeneration and retinal detachments are well known sequelae of high myopia. [disorders.eyes.arizona.edu]
Inheritance - congenital achromatopsia is transmitted in an autosomal-recessive trait Presentation - patients present in early childhood with nystagmus, abnormal visual behaviour or photophobia. Acuity is less than 20/200. [patient.info]
Presents a more streamlined format to the printed text to help you focus on the clinically actionable information you need everyday. [books.google.ro]
Entire Body System
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Cerebral Palsy
Cerebral palsy is the most common cause of secondary dystonia. Primary dystonia may be sporadic or inherited (Jankovic, 2007). Cases with onset in childhood usually are inherited in an autosomal dominant pattern. [aetna.com]
Musculoskeletal
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Long Arm
Ideogram of the long arm of chromosome 17, region 21-23 with the markers within the interval containing the high myopia locus. [iovs.arvojournals.org]
New locus for autosomal dominant high myopia maps to the long arm of chromosome 17. Invest Ophthalmol Vis Sci. 2003; 44:1830-6. [PMID: 12714612] Zhang Q, Guo X, Xiao X, Jia X, Li S, Hejtmancik JF. [molvis.org]
New locus for autosomal dominant high myopia maps to the long arm of chromosome 17. Invest Ophthalmol Vis Sci 2003;44:1830-6. 19. Young TL, Ronan SM, Alvear AB, Wildenberg SC, Oetting WS, Atwood LD, et al. [ijo.in]
Paluru P, Ronan SM, Heon E, Devoto M, Wildenberg SC, et al. (2003) New locus for autosomal dominant high myopia maps to the long arm of chromosome 17. Invest Ophthalmol Vis Sci 44: 1830–1836. View Article Google Scholar 22. [journals.plos.org]
View Article PubMed PubMed Central Google Scholar Paluru P, Ronan SM, Heon E, Devoto M, Wildenberg SC, Scavello G, Holleschau A, Makitie O, Cole WG, King RA, Young TL: New locus for autosomal dominant high myopia maps to the long arm of chromosome 17. [bmcmedgenet.biomedcentral.com]
Treatment
Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. [books.google.com]
There are no proven treatments that halt the progressive enlargement of the eyeball and the only treatment of myopia known to correct vision is with the use of proper corrective lenses. [disorders.eyes.arizona.edu]
At present, there is no treatment for this condition. [afb.org]
Helps you make optimal use of the newest drug therapies, including Anti-VEGF treatment for wet ARMD and bevacizumab treatment for complications of diabetes. [books.google.ro]
Prognosis
Diagnosis and Prognosis: The diagnosis of myopia is made by an eye professional. [disorders.eyes.arizona.edu]
Prognosis - there is no progression. [patient.info]
Affected individuals should talk to their physician and medical team about their specific case, associated symptoms and overall prognosis. [rarediseases.org]
[…] retinopathy caused by shaken baby syndrome: a. the patient is usually between the age of 3 and 5 years of age b. the retinopathy may resemble central retinal vein occlusion c. neurological damage is common d. skull fracture is always present e. the visual prognosis [mrcophth.com]
Galil et al. (1991) described the physical, motor, cognitive, and academic development of a child with WZS from birth to the age of 8 years and suggested a more favorable prognosis for both physical and psychomotor development than previously reported [genome.jp]
Etiology
Models of myopia development The exact etiology and progression of myopia have been investigated for many decades. [news-medical.net]
We therefore speculate that there might be a possibility of an etiologic link between these entities. [link.springer.com]
Similarly, many patients report chronic fatigue, which may affect education and can manifest as inattention or poor concentration. 11 The etiology of the fatigue is likely heterogeneous, in part because of the underlying chronic condition, medications [pediatrics.aappublications.org]
Environmental factors such as work at close range and prolonged reading are suggested to be involved in the progression of myopia [ 1, 12, 13 ] and a body of evidence supports the idea that heredity plays a central role in the etiology of myopia. [molvis.org]
Can’t wait to find out the etiology of the folds! Also ordered a B-scan (for the drusen). This patient not interested in any membrane peeling so no point going any further with that.. .. [picstoc.com]
Epidemiology
Chapters on epidemiology, embryology, non-syndromic hearing loss, and syndromic forms of hearing loss have all been updated with particular attention to the vast amount of new information on molecular mechanisms, and chapters on clinical and molecular [books.google.com]
The following contribution on the epidemiology of hereditary ocular disorders provides an excellent reference to geneticists as well as clinicians. [books.google.de]
Recessive Epidemiology: Most Caucasian; 10 patients Clinical Onset age: 8 months to 7 years Extrapyramidal Dystonia Rigidity Choreoathetosis Cerebellum: Ataxia; Nystagmus Spasticity Mental development Poor speech Mental deficiency: Mild to Severe Other [neuromuscular.wustl.edu]
Generally, myopia is the result of elongated axial length in the region of 25.5 or 26.5mm. (1,2) Degenerative myopia is also known as other terminology including: High Myopia Degenerative Myopia Pernicious Myopia Malignant Myopia EPIDEMIOLOGY The epidemiology [optometrystudents.com]
Pathophysiology
Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any [books.google.com]
Identifying the genetic markers for myopia would be a useful step toward understanding the molecular defects that lead to the pathophysiology of myopia. [molvis.org]
The prevalence of myopia is increasing, especially in Asian countries, thus both understanding the pathophysiology and timely diagnosis represent are pivotal in tackling this problem. [news-medical.net]
The identification of this gene may provide insight into the pathophysiology of myopia and eye development.” Here is what I want to show you. [endmyopia.org]
Ongoing genetic research continues to change the understanding of pathophysiology. Stargardt's disease and fundus flavimaculatus [ 3 ] There has been some question as to whether this condition is two diseases or one. [patient.info]
Prevention
TREATMENT Prevention of Myopia in Otherwise Healthy Infants and Children Over the years, several rationales for the possibility of prevention of myopia have been proposed. [entokey.com]
Early detection through regular eye examination and prompt treatment is essential to prevent vision loss. [afb.org]
The research was supported by the National Institutes of Health (R01 EY014685), the Lew Wasserman Award from Research to Prevent Blindness Inc., a Duke-NUS core grant, the Toulouse Hospital Young Researcher Fellowship, the Fondation pour la Recherche [sciencedaily.com]
While research studies are promising, it could be years before scientists uncover conclusive evidence that might lead to more exacting risk predictors and preventive interventions. [eyeque.com]