Presentation
Pathologic studies indicate that a posterior staphyloma is present in as many as 35 percent of eyes, although this is frequently underestimated during clinical examinations.3 Histopathologic studies demonstrate that retinal degeneration is present in [aao.org]
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment. [orpha.net]
Case presentation A 56-year-old Caucasian woman presented with a best-corrected visual acuity of 6/6-1 in her right eye and 6/24 in her left. [jmedicalcasereports.com]
A variety of topics were presented which engaged the attendees and sparked an in-depth discussion about the cases each of our doctors highlighted. [illinoisretina.com]
But rarely, these congenital malformations may present in young adults and they most commonly present with discharge through the umbilicus. [ispub.com]
Entire Body System
- Weakness
Correlation of MMD severity was strong for subfoveal CT (r = -0.70, P < 0.001) but weak for subfoveal ST (r = -0.31, P = 0.01). [ncbi.nlm.nih.gov]
Degenerative myopia that is associated with systemic diseases such as Marfan syndrome and Ehlers-Danlos syndrome can also associated with zonular weakness which can lead to higher incidence of lens dislocation. 4- Vitreous Body Posterior vitreous detachment [webeyeclinic.com]
• Retinal Tear and Detachment: People with severe short-sightedness (high myopia, pathological myopia) have an increased chance of having weak areas in the peripheral retina compared to normal people, which can result in retinal tears and detachment [strathfieldretina.com.au]
- Disability
Pathological myopia (PM) is one of the leading causes of visual disability in the world from 20-50 years of age.[1] Prevalence rates of PM vary between 2 and 9%, depending on the race and age of the population. [medscape.com]
About your students. that would be a good lesson to teach them how to respect people who have disability. [afb.org]
We look forward to the planned initiation of our comprehensive Phase 2 safety study in dry AMD and a pivotal study in SMD, two disabling diseases where there is no cure available today.” [businesswire.com]
It is a disabling and painful condition which can lead to... 882 Members Arthritis - Juvenile Juvenile idiopathic arthritis (JIA), formerly known as juvenile rheumatoid arthritis (JRA), is the most common form of persistent arthritis in... 58 Members [dailystrength.org]
Although macular degeneration is almost never a totally blinding condition, it can be a source of significant visual disability. There are two main types of age-related macular degeneration: Dry form. [webmd.com]
- Fever
Fever (but not everyone with the flu gets a fever) or feeling feverish/chills; Muscle or body aches. [deporteintegra.eu]
Other symptoms can accompany a discharge, such as abdominal pain, fever, and pain when a person urinates. Sebaceous cysts are also a cause of belly button discharge in some cases. The sebaceous glands release oil in the skin. [medicalnewstoday.com]
- Camping
^ Yang Z, Camp NJ, Sun H, Tong Z, Gibbs D, Cameron DJ, et al. (November 2006). "A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration". Science. 314 (5801): 992–3. [en.wikipedia.org]
Gastrointestinal
- Abdominal Pain
Discharge and abdominal pain The presence of pain and discharge from the navel can be associated with problems with abdominal operations, tightening or abnormal development of urachus, especially with bladder cysts. [semedic.ru]
Other symptoms can accompany a discharge, such as abdominal pain, fever, and pain when a person urinates. Sebaceous cysts are also a cause of belly button discharge in some cases. The sebaceous glands release oil in the skin. [medicalnewstoday.com]
Skin
- Flushing
Ask the RS to further dilute the Betadine and to repeatedly flush with lots of saline solution after the shot. [mdsupport.org]
[…] the fifth decade.[40] Posterior staphyloma formation is further linked to development of myopic maculopathy.[3] The eyes with shallow staphylomas show a larger drop in VA and a greater occurrence of CNV and macular hemorrhage.[41] The normal choroidal flush [ncbi.nlm.nih.gov]
Eyes
- Scotoma
Thus, biofeedback training using MP-1 can improve the visual function in patients with macular diseases and central scotoma. [ncbi.nlm.nih.gov]
The scotoma density was defined based on the threshold values: Normal function-threshold values of ≥10 dB; relative scotoma-threshold values of ≤10 dB and an absolute scotoma was present if no threshold could be seen. [5], [6] Best corrected visual acuity [ijo.in]
Eyes with PA generate patchy scotoma in PA lesions and reduced retinal sensitivity in regions beyond atrophic lesion on microperimetry. [physiciansweekly.com]
Floaters are of two primary types--lets call them "fixed" or stationary floaters (also called scotomas) and "mobile" floaters. [healthtap.com]
Central scotomas (shadows or missing areas of vision) Distorted vision (i.e. metamorphopsia) - A grid of straight lines appears wavy and parts of the grid may appear blank. Patients often first notice this when looking at mini-blinds in their home. [visivite.com]
- Vitreous Floaters
These side effects may include eye pain, subconjunctival hemorrhage (bloodshot eye), vitreous floaters, irregularity or swelling of the cornea, inflammation of the eye, and visual disturbances. [maculacenter.com]
These side effects may include eye pain, subconjunctival hemorrhage (bloodshot eye), vitreous floaters, swelling of the cornea, inflammation of the eye, and visual disturbances. [retinacare.org.uk]
- Retinal Hemorrhage
Figure 1 – Fundus images of 2 patients demonstrating the tessellated appearance (A), attenuated vasculature and peripapillary atrophy with associated retinal hemorrhage (C). [retinacare.org.uk]
I had already had a massive sub-retinal hemorrhage in my right eye, and my left eye had just begun to leak (all within 2 years time since the onset of the discovery of the first bleed). [mdsupport.org]
Workup
This dr. also did a full workup and looked at both eyes & point blank told me I will be legally blind in less then 2 years. So now I am on line reading what everyone has to say about it, and I'm scared. [afb.org]
Treatment
Treatment resulted in complete absence of angiographic leakage in 90.9% of eyes at 3 months and 2 (9.1%) eyes required further treatment up to 6 months. [retina3000.it]
Ways to Prevent Myopic Maculopathy There is currently no treatment to prevent myopic maculopathy. [healthhub.sg]
Myopic CNV respond well to anti-VEGF treatment, needing less treatment that pure ARMD. The long term prognosis is getting better. Younger patients have a better prognosis..the CNV get walled off. [goodhopeeyeclinic.org.uk]
There are no treatments available to stop the complications of high or pathological myopia. This is because it is not possible to control the growth of the eye. Currently treatment is aimed at managing complications when they happen. [mdfoundation.com.au]
Prognosis
The long term prognosis is getting better. Younger patients have a better prognosis..the CNV get walled off. All types of wet ARMD (CNV) will progress 4 times faster in smokers, a 400% increase. [goodhopeeyeclinic.org.uk]
Treatment for Myopic Macular Degeneration If you are squeamish, skip right on down to the next section, Long Term Prognosis. [insightfulllife.com]
One of the most serious complications of MMD is myopic choroidal neovascularization (mCNV), which often leads to a sudden and progressive decline in central vision and is associated with a poor prognosis unless treated. [evrs.eu]
We analysed the visual prognosis for the different types of macular degeneration and its related factors. [ncbi.nlm.nih.gov]
Hotchkiss and Fine 13 in a retrospective study also observed a poor visual prognosis and 20 of 27 eyes had a legal blindness. [retina3000.it]
Etiology
Introduction The degenerative myopia is often associated with blindness and the etiology is still not clear. [medical-clinical-reviews.imedpub.com]
Etiology of choroidal neovascularization in young patients. Ophthalmology. 1996;103(8):1241-1244. Ohno-Matsui K, Yoshida T, Futagami S, et al. [retinatoday.com]
If a navel is sore in an adult and a purulent fluid is released, but internal organic changes during ultrasound examination are not detected, regardless of the etiology of the disease, the diagnosis is omphalitis. [semedic.ru]
Epidemiology
Figure 2 Prevalence of any myopic macular degeneration (MMD) in adults aged 40 to 80 years in the Singapore Epidemiology of Eye Diseases (SEED) study stratified by age group and myopia level (N = 8716). [iovs.arvojournals.org]
Epidemiology and disease burden of pathologic myopia and myopic choroidal neovascularization: an evidence-based systematic review. [ncbi.nlm.nih.gov]
Kovin Naidoo Epidemiological data are lacking on the prevalence of myopia, high myopia and vision impairment associated with high myopia in Africa, Central America, South America and Oceania; the experts suggest these areas should be a priority for future [healio.com]
From the American Journal of Epidemiology : Data from the first National Health and Nutrition Examination Survey collected between 1971 and 1972 were used to determine what factors are associated with the prevalence of age-related macular degeneration [endmyopia.org]
Pathophysiology
He has spent his career studying ocular biomechanics, focusing in particular on biomechanics and mechanobiology of the optic nerve head (ONH), sclera, and lamina cribrosa to better understand the pathophysiology of glaucoma, a leading cause of irreversible [ophth.wisc.edu]
Although the pathophysiology is unknown, there are evidences - as the world standard for the disease distribution-indicating genetic influences. [medical-clinical-reviews.imedpub.com]
The pathophysiology of geographic atrophy is still uncertain. [en.wikipedia.org]
[…] in the development of HM.[22,23] Twin studies report high heritability values of up to 90%.[24] Currently, the most studied environmental parameter thought to be protective against development of myopia is time spent by children outdoors.[25,26,27] Pathophysiology [ncbi.nlm.nih.gov]
Prevention
Ways to Prevent Myopic Maculopathy There is currently no treatment to prevent myopic maculopathy. [healthhub.sg]
Early diagnosis and medical monitoring of myopic macular degeneration are key to preventing the disease from causing irreparable damage to vision. [areaoftalmologica.com]
Hopefully better understanding of this condition will lead to improved preventions and treatments. [brightfocus.org]
Myopic Macular Degeneration Prevention Study Myopic Macular Degeneration Prevention Study Glaucoma Up Laser Follow Trial Glaucoma Up Laser Follow Trial #5: Make and freeze large. At least once during your 20s and twice during your 30s. [deporteintegra.eu]