Ocular signs are present in 90% of heterozygous females. These are typically lens opacities often involving the posterior Y sutures. More rarely dental anomalies and the characteristic facial features may also occur. [en.wikipedia.org]

• Turkish

  "A Turkish family with Nance-Horan syndrome due to a novel mutation". Gene. 525 (1): 141–145. doi:10.1016/j.gene.2013.03.094. PMID 23566852. ^ Horan, Margaret B.; Billson, F. A. (1974). "X-Linked Cataract and Hutchinsonian Teeth". [en.wikipedia.org]

• Developmental Delay

  Other:[2] The fourth metacarpal may be shortened 30% of patients also have some degree of intellectual impairment: of these 80% are mildly to moderately affected: the other 20% may have developmental delays and behavior problems. [en.wikipedia.org]

• Disability

  Nance–Horan syndrome is a rare X-linked dominant syndrome characterized by congenital cataracts leading to profound vision loss, characteristic dysmorphic features, and dental anomalies.[1][2] Microcornea, microphthalmia, and mild or moderate intellectual disability [en.wikipedia.org]

• Prognathism

  […] shape) widely separated teeth (diastemma) hypoplastic enamel dental agenesis presence of mesiodents (median incisor behind normal upper incisors) pulp chamber anomalies Facial features:[2] anteverted pinnae long face prominent nasal bridge and nose prognathism [en.wikipedia.org]

• Hutchinson's Teeth

  Presentation[edit] Dental features:[2] small teeth in males pointed (screwdriver shaped or conical) incisors (sometimes called Hutchinson teeth) incisors with an irregular incisal edge canines: enlarged and globular; may be dome or bud shaped with trilobed [en.wikipedia.org]

• Small Teeth

  Presentation[edit] Dental features:[2] small teeth in males pointed (screwdriver shaped or conical) incisors (sometimes called Hutchinson teeth) incisors with an irregular incisal edge canines: enlarged and globular; may be dome or bud shaped with trilobed [en.wikipedia.org]

• Short Arm

  [citation needed] Genetics[edit] This syndrome is caused by mutations in the Nance Horan gene (NHS) which is located on the short arm of the X chromosome (Xp22.13).[3] Diagnosis[edit] This section is empty. You can help by adding to it. [en.wikipedia.org]

• Strabismus

  […] incisors) pulp chamber anomalies Facial features:[2] anteverted pinnae long face prominent nasal bridge and nose prognathism occasionally Ophthalmic features:[citation needed] bilateral congenital nuclear opacities (100%) severe amblyopia nystagmus (93%) strabismus [en.wikipedia.org]

• Visual Impairment

  impairment in affected males. [en.wikipedia.org]

• Visual Impairment

  impairment in affected males. [en.wikipedia.org]

• Behavior Problem

  Other:[2] The fourth metacarpal may be shortened 30% of patients also have some degree of intellectual impairment: of these 80% are mildly to moderately affected: the other 20% may have developmental delays and behavior problems. [en.wikipedia.org]

• Nystagmus

  […] normal upper incisors) pulp chamber anomalies Facial features:[2] anteverted pinnae long face prominent nasal bridge and nose prognathism occasionally Ophthalmic features:[citation needed] bilateral congenital nuclear opacities (100%) severe amblyopia nystagmus [en.wikipedia.org]