The presentation of this case aims to encourage health care professionals to consider this entity as a differential diagnosis in similar cases. [revistas.unal.edu.co]

• Pain

  The first clinical manifestations of ENKL are usually local and the most common symptoms include epistaxis, mass sensation, nasal obstruction, and face pain and swelling (5); the latter two were observed in the reported patient. [revistas.unal.edu.co]

• Ulcer

  Soft or hard palate edema may also occur, which occasionally progress to deep necrotic ulceration, as in this case. [revistas.unal.edu.co]

Blood count on admission and on the fifth day of antimicrobial treatment. [revistas.unal.edu.co]

It has an aggressive course, and its prognosis is severe, with an average survival rate between 6 and 25 months (4). [revistas.unal.edu.co]

Although the etiology of this disease is unknown, some authors consider Epstein-Barr virus as an oncogenic factor because this infection causes neoplastic transformation of natural killer (NK) cells. [revistas.unal.edu.co]

Aggressive mature natural killer cell neoplasms: from epidemiology to diagnosis. Orphanet J Rare Dis. 2013;8(1):95. https://doi.org/fvb9. 16.International Non-Hodgkin’s Lymphoma Prognostic Factors Project. [revistas.unal.edu.co]