Edit concept Question Editor Create issue ticket

Nasopharyngeal Disease


Presentation

  • Although NPC is endemic in some areas of Asia, it is uncommon in the United States and little is known about how it presents in children.[enttoday.org]
  • […] by MHC class I molecules N00480 EBV BILF1 to antigen processing and presentation by MHC class I molecules N00481 EBV BZLF1 to p53-mediated transcription N00482 EBV EBNA3C to p27-Cell cycle G1/S N00483 EBV EBNA3C to cell cycle G1/S N00484 EBV EBNA3C to[genome.jp]
  • Takhtani D, Melhem ER, Carson BS (2000) A heterotopic cerebellum presenting as a suprasellar mass with associated nasopharyngeal teratoma. AJNR 21: 1119–1121 PubMed Google Scholar 21. Wittekind C, Meyer H, Bootz F (Hrsg) (2002) Pharynx.[link.springer.com]
  • We present a case of optic neuritis as the first clinical manifestation of NPC. Case report A 55-year-old Taiwanese woman presented with pain and decreased vision in the right eye of about one week duration.[nature.com]
  • Clinical presentation includes epistaxis and conductive hearing loss.[radiopaedia.org]
Amyloidosis
  • Motosugi U, Ichikawa T, Araki T et al. (2007) Localized nasopharyngeal amyloidosis with remarkable early enhancement on dynamic contrast-enhanced MR imaging. Eur Radiol 17: 852–853 PubMed CrossRef Google Scholar 14.[link.springer.com]
Pseudotumor
  • De Vuysere S, Hermans R, Sciot R et al. (1999) Extraorbital inflammatory pseudotumor of the head and neck: CT and MR findings in three patients. AJNR 20: 1133–1139 Google Scholar 4.[link.springer.com]
Hodgkin's Disease
  • Epstein Barr virus-specific cytotoxic T lymphocytes expressing the anti-CD30 artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease. Blood. 2007; 110 :2620-2630 55. Comoli P.[jcancer.org]
Sore Throat
  • throat Headaches When to see a doctor Early nasopharyngeal carcinoma symptoms may not always prompt you to see your doctor.[mayoclinic.org]
  • Fever, sore throat, and lymhadenopathy, 2. an associated absolute lymphocytosis ( 50% of which at least 10% are atypical lymphocytes in the peripheral blood), 3. development of transient heterophil and persistent antibody responses against EBV and 4.[ibl-international.com]
  • 2018 2019 Billable/Specific Code Applicable To Gangrenous pharyngitis (acute) Infective pharyngitis (acute) NOS Pharyngitis (acute) NOS Sore throat (acute) NOS Suppurative pharyngitis (acute) Ulcerative pharyngitis (acute) J02.9 ) The following code([icd10data.com]
  • throat Keep in mind, such symptoms are more likely to occur with many other diseases and health conditions that are far less serious than nasopharyngeal cancer.[webmd.com]
Sleep Apnea
  • Since it is portable and simple to operate, it is useful in screening for sleep apnea syndrome.[jstage.jst.go.jp]
Ptosis
  • Horner syndrome (HS) is produced by damage to the oculosympathetic pathway and gives rise to palpebral ptosis, enophthalmos and myosis.[neurologia.com]
Paresis
  • Signs and symptoms related to the primary tumor include trismus, pain, otitis media, nasal regurgitation due to paresis (loss of or impaired movement) of the soft palate, hearing loss and cranial nerve palsy (paralysis).[en.wikipedia.org]

Treatment

  • Further chapters then explore surgical treatment, follow-up, treatment of metastatic disease, treatment-related complications, and nasopharyngeal cancer in children.[books.google.de]
  • To fill this gap, investigators used data from the National Cancer Data Base from January 1998 to 2011 to identify patients with NPC and to analyze data (demographic, tumor, and treatment characteristics) to understand the difference between pediatric[enttoday.org]
  • Several prospective randomized trials and meta-analyses have shown that concurrent chemoradiotherapy with or without adjuvant chemotherapy is superior to radiotherapy alone in the treatment of locoregionally advanced nasopharyngeal carcinoma, the researchers[ascopost.com]
  • Treatment for nasopharyngeal carcinoma usually involves radiation therapy, chemotherapy or a combination of the two. You can work with your doctor to determine the exact approach depending on your particular situation.[mayoclinic.org]
  • A detailed evolution of the current standard of care, and new techniques and treatment options will be reviewed. Intergroup 0099 established the role for chemoradiotherapy (chemo-RT) in the treatment of nasopharyngeal carcinoma.[dovepress.com]

Prognosis

  • In addition, some information on prognosis, staging, treatment and treatment related complications in this group of patients is provided. Copyright 2015 Elsevier Inc. All rights reserved.[ncbi.nlm.nih.gov]
  • Prognosis for patients with recurrent or metastatic nasopharyngeal carcinoma — accounting for approximately 10% of all cases — is poor,” Chiun Hsu, MD, PhD, professor in the graduate institute of oncology at National Taiwan University Hospital, and colleagues[healio.com]
  • Prognosis and survival are inversely proportional to the geometrical mean titres of VCA and EA antibodies. 2.[drtbalu.co.in]
  • A clinical study comprising 124 cases with special reference to clinical presentation and prognosis. Neurosurg Rev 1998; 21 : 243–248 2 Carlin L, Biller J, Laster DW, Toole JF. Monocular blindness in nasopharyngeal cancer.[nature.com]

Etiology

  • […] anatomy and histology blood blood supply cerebrospinal fluid chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology[ncbi.nlm.nih.gov]
  • […] geographic regions (Far East) and ethnic groups (Chinese origin) Content is based on one of the largest single institutional studies ever undertaken, plus an extensive review of the international literature Encompasses every aspect of the field, from etiology[thieme.de]
  • Abstract: Nasopharyngeal carcinoma (NPC) is a form of head and neck cancer of multifactorial etiologies that is highly prevalent among men in the population of Southern China and Southeast Asia.[eurekaselect.com]
  • The field of other/contributing etiological factors are only partially known and recently a subset of this carcinoma has been linked to transcriptionally active Human Papilloma virus.[ncbi.nlm.nih.gov]
  • Over several generations, the prevalence among Chinese-Americans gradually decreases to that among non-Chinese Americans, suggesting an environmental component to etiology.[merckmanuals.com]

Epidemiology

  • The first ten chapters document contain essential background information on subjects such as epidemiology, pathogenesis, molecular biology, pathology, and the use of imaging in diagnosis and staging.[books.google.de]
  • […] options Subheadings: analysis anatomy and histology blood blood supply cerebrospinal fluid chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology[ncbi.nlm.nih.gov]
  • Title Advances in cancer epidemiology: understanding causal mechanisms and the evidence for implementing interventions.[genome.jp]
  • Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.[headandneckcancerguide.org]
  • "The Enigmatic Epidemiology of Nasopharyngeal Carcinoma". Cancer Epidemiology, Biomarkers & Prevention. 15 (10): 1765–1777. doi : 10.1158/1055-9965.EPI-06-0353. PMID 17035381. Li, Yvonne Y.; Chung, Grace T. Y.; Lui, Vivian W.[en.wikipedia.org]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology The detection of the Epstein-Barr virus (EBV) nuclear antigen and viral DNA in nasopharyngeal carcinoma has revealed that EBV can infect epithelial cells and is associated with their malignant transformation. [1] Copies of the EBV genome[emedicine.medscape.com]

Prevention

  • […] imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology genetics history immunology metabolism microbiology mortality nursing organization and administration parasitology pathology physiology physiopathology prevention[ncbi.nlm.nih.gov]
  • Prevention No sure way exists to prevent nasopharyngeal carcinoma. However, if you're concerned about your risk of nasopharyngeal carcinoma, you may consider avoiding habits that have been associated with the disease.[mayoclinic.org]
  • NPC has claimed many thousands of lives worldwide; but the low awareness of NPC remains a hindrance in early diagnosis and prevention of the disease.[eurekaselect.com]
  • This gene cluster is deleted in about 40% of NPC tumors, suggesting that they are crucial for preventing cancerous growth. Additionally, this same SNP CDKN2A/CDKN2B SNP associated with NPC risk has been linked to glioma in European populations.[blog.23andme.com]
  • Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.[headandneckcancerguide.org]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!