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Nasopharyngeal Disease
Disease Nasopharyngeal

Presentation

Although NPC is endemic in some areas of Asia, it is uncommon in the United States and little is known about how it presents in children. [enttoday.org]

We present a case of optic neuritis as the first clinical manifestation of NPC. Case report A 55-year-old Taiwanese woman presented with pain and decreased vision in the right eye of about one week duration. [nature.com]

Clinical presentation includes epistaxis and conductive hearing loss. [radiopaedia.org]

[…] by MHC class I molecules N00480 EBV BILF1 to antigen processing and presentation by MHC class I molecules N00481 EBV BZLF1 to p53-mediated transcription N00482 EBV EBNA3C to p27-Cell cycle G1/S N00483 EBV EBNA3C to cell cycle G1/S N00484 EBV EBNA3C to [genome.jp]

Symptoms and Signs Nasopharyngeal cancer often presents with palpable lymph node metastases in the neck. Another common presenting symptom is hearing loss, usually caused by nasal or eustachian tube obstruction leading to a middle ear effusion. [merckmanuals.com]

Respiratoric

  • Sleep Apnea

    Apnea indices were improved in all 11 patients tested. The Apnomonitor cannot differentiate waking from sleeping during apnea, or central apnea from obstructive apnea. It simply shows the presence or absence of apnea during sleep. [jstage.jst.go.jp]

Treatment

Further chapters then explore surgical treatment, follow-up, treatment of metastatic disease, treatment-related complications, and nasopharyngeal cancer in children. [books.google.de]

Recurring tumors have worse prognosis compared to tumors that do not recur Response to treatment: Tumors that respond to treatment have better prognosis than tumors that do not respond to treatment Almost all individuals diagnosed and treated for stage [dovemed.com]

Clinical presentation, prior treatment, histological type and grade, clinical stage, details of surgical treatment, and postoperative adjuvant radiation therapy were studied. [thedoctorsdoctor.com]

After Treatment Get information about how to live well after nasopharyngeal cancer treatment and make decisions about next steps. [cancer.org]

Summary of the Treatment Patients will be treated in 1 of 2 ways depending on the stage of the disease: Treatment Group 1: Patients with early stages of disease will get radiation therapy only. [childrensoncologygroup.org]

Prognosis

[…] have better prognosis compared to those with poor health Age of the individual: Older individuals generally have poorer prognosis than younger individuals Whether the tumor is occurring for the first time, or is a recurrent tumor. [dovemed.com]

Nasopharyngeal carcinoma (NPC) 5 is often diagnosed at a late stage with concomitant poor prognosis ( 1 – 2 ). [clinchem.aaccjnls.org]

In addition, some information on prognosis, staging, treatment and treatment related complications in this group of patients is provided. Copyright © 2015 Elsevier Inc. All rights reserved. [ncbi.nlm.nih.gov]

NPC is a malignancy arising at the upper lining of nasopharynx, and the strategies for early diagnosis and prognosis are keys for NPC survival. [ijbs.com]

“Prognosis for patients with recurrent or metastatic nasopharyngeal carcinoma — accounting for approximately 10% of all cases — is poor,” Chiun Hsu, MD, PhD, professor in the graduate institute of oncology at National Taiwan University Hospital, and colleagues [healio.com]

Etiology

[…] anatomy and histology blood blood supply cerebrospinal fluid chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology [ncbi.nlm.nih.gov]

[…] geographic regions (Far East) and ethnic groups (Chinese origin) Content is based on one of the largest single institutional studies ever undertaken, plus an extensive review of the international literature Encompasses every aspect of the field, from etiology [thieme.de]

Abstract: Nasopharyngeal carcinoma (NPC) is a form of head and neck cancer of multifactorial etiologies that is highly prevalent among men in the population of Southern China and Southeast Asia. [eurekaselect.com]

Over several generations, the prevalence among Chinese-Americans gradually decreases to that among non-Chinese Americans, suggesting an environmental component to etiology. [merckmanuals.com]

Epidemiology

The first ten chapters document contain essential background information on subjects such as epidemiology, pathogenesis, molecular biology, pathology, and the use of imaging in diagnosis and staging. [books.google.de]

Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. [headandneckcancerguide.org]

[…] options Subheadings: analysis anatomy and histology blood blood supply cerebrospinal fluid chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology [ncbi.nlm.nih.gov]

Title Advances in cancer epidemiology: understanding causal mechanisms and the evidence for implementing interventions. [genome.jp]

"The Enigmatic Epidemiology of Nasopharyngeal Carcinoma". Cancer Epidemiology, Biomarkers & Prevention. 15 (10): 1765–1777. doi : 10.1158/1055-9965.EPI-06-0353. PMID 17035381. ^ Li, Yvonne Y.; Chung, Grace T. Y.; Lui, Vivian W. [en.wikipedia.org]

Pathophysiology

Pathophysiology The detection of the Epstein-Barr virus (EBV) nuclear antigen and viral DNA in nasopharyngeal carcinoma has revealed that EBV can infect epithelial cells and is associated with their malignant transformation. [1] Copies of the EBV genome [emedicine.medscape.com]

Prevention

This study examined the role of diets in the development and prevention of nasopharyngeal cancer. Researchers reviewed data and evidence extracted from several studies. [drcarney.com]

Prevention No sure way exists to prevent nasopharyngeal carcinoma. However, if you're concerned about your risk of nasopharyngeal carcinoma, you may consider avoiding habits that have been associated with the disease. [mayoclinic.org]

[…] imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology genetics history immunology metabolism microbiology mortality nursing organization and administration parasitology pathology physiology physiopathology prevention [ncbi.nlm.nih.gov]

Causes, Risk Factors, and Prevention Learn about the risk factors for nasopharyngeal cancer and what you might be able to do to help lower your risk. Early Detection, Diagnosis, and Staging Know the signs and symptoms of nasopharyngeal cancer. [cancer.org]

NPC has claimed many thousands of lives worldwide; but the low awareness of NPC remains a hindrance in early diagnosis and prevention of the disease. [eurekaselect.com]

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