Presentation
Seven patients (six males and one female) with radiation-associated temporal bone tumours are presented (five squamous cell carcinomas, one osteogenic sarcoma and one chondrosarcoma). [ncbi.nlm.nih.gov]
Case Presentation We present a 24 year old Asian female student presented with acute diminution of vision in both eyes 4 years back followed by complete loss of vision one year later in both eyes. [npplweb.com]
In North America, around 25% of patients present kind I, 12% presents kind II and 63% present kind III(4). [arquivosdeorl.org.br]
Unilateral cervical lymphadenopathy was present in 4 (36%) and bilateral in 7 (64%). Lateral retropharyngeal lymphadenopathy that measured greater than 1 cm in maximal transverse dimension was present in 10 (91%). [ajnr.org]
Log In or Register to continue Aug 24, 2017 | Posted by in OTOLARYNGOLOGY | Comments Off on Large nasopharyngeal inverted papilloma presenting with rustling tinnitus [entokey.com]
Gastrointestinal
- Diarrhea
My mom had diarrhea the day after treatment. She also had a little nausea. She will get another treatment in 2 days. They will give it to her every week. She also takes decadron before each Chemo. [cancercompass.com]
There are effective and readily available medications to address traditional side effects from cancer treatment (such as nausea, diarrhea, constipation and mouth sores.) [cancersupportcommunity.org]
Avoid with diarrhea or high or low blood pressure. Avoid taking pomegranate fruit husk with oil or fats to treat parasites. Pomegranate root/stem bark should only be used under the supervision of a qualified healthcare professional. [livingnaturally.com]
Jaw & Teeth
- Halitosis
Other symptoms include bleeding causing haemoptysis, halitosis, trismus (suggests involvement of the pterygoid muscles) and weight loss. See the separate articles on Problems in the Mouth, Oral Ulceration and Salivary Gland Disorders. [patient.info]
Eyes
- Diplopia
[…] and numbness of the face 21. 21 • neck lump - 60% • block sensation of ear - 41% • hearing loss - 37% • nasal bleeding - 30% • nasal obstruction - 29% • headache - 16% • ear pain - 14% • neck pain -13% • weight loss 10% • diplopia - 10% 22. 22 23. 23 [slideshare.net]
NASOPHARYNX TUMOUR (WITH GERMINATION IN THE HEAD CAVITY) The 38-year-old woman showed complaints to a diplopia and pains in the right eye-socket and an upper jaw. [infomeds.net]
Actual presentation is often delayed until more sinister signs are evident, including nodal masses in the neck (most common), cranial nerve palsies, tinnitus, headache, or even diplopia and proptosis 1,2. [radiopaedia.org]
Upon presentation, his physical exam was significant for horizontal diplopia with rightward gaze, which was worse at distance. There also was left eye nystagmus with the fast component to the left with a right gaze. [healio.com]
Face, Head & Neck
- Epistaxis
The most common symptoms were nasal obstruction (100%), epistaxis (75%) and rhinorrhea (50%), findings which agree on the nasoangiofibroma literatur(2). [arquivosdeorl.org.br]
Clinical presentation includes epistaxis and conductive hearing loss. [radiopaedia.org]
[…] and Nasorespiratory Symptoms • blood stained nasal discharge • blood stained saliva on hawking • profuse epistaxis • nasal obstruction • ozanea due to tumor necrosis 26. 26 Neurological Palsies • Most frequently involved are: VI - Lateral rectus palsy [slideshare.net]
Other symptoms include ear pain, purulent bloody rhinorrhea, frank epistaxis, cranial nerve palsies, and cervical lymphadenopathy. [merckmanuals.com]
Exclusion Criteria: Presence of local recurrence Presence of neck lymph node recurrence invading vascular structure; Presence of central lung lesions involving major blood vessels; History of hemoptysis or epistaxis within 4 weeks; Preexisting uncontrolled [clinicaltrials.gov]
- Facial Pain
Grade 3-5 investigator-assessed, treatment-related adverse events were hepatitis (n = 2); pneumonitis (n = 2); anemia (n = 1); facial pain (n = 1); increased blood creatine phosphokinase (n = 1); proteinuria (n = 1); and sepsis (n = 1). [ascopost.com]
pain); 4- cervical adenomegalies. [arquivosdeorl.org.br]
Sore throat : Oropharyngeal extension Pain : Compression of Vth cranial nerve ( facial pain) Trismus : Mandibular nerve involvement or pterygoid muscle invasion. 11. Cranial Nerve involvement 12. [slideshare.net]
Neurologic
- Confusion
NPC is one of the most confusing, commonly misdiagnosed, and poorly understood diseases. NPC has a remarkable racial and geographical distribution [ 1, 2 ]. [npplweb.com]
Nasopharyngeal cancer shouldn't be confused with other types of cancer that also affect the throat, such as laryngeal cancer and oesophageal cancer. [nhs.uk]
But the condition can quickly progress to shock, which is marked by falling blood pressure and body temperature, confusion, clotting abnormalities and bleeding into the skin. Blood poisoning is a medical emergency and can be fatal if left untreated. [livingnaturally.com]
LA GUÉRISON EST TOTALE APRÈS EXÉRÈSE COMPLÈTE. 1.8 : DIAGNOSTIC : UN LÉIOMYOSARCOME DE BAS GRADE DE MALIGNITÉ PEUT PRÊTER À CONFUSION AVEC UN LÉIOMYOME BÉNIN. LE NOMBRE DE MITOSES ET LES ATYPIES NUCLÉAIRES PERMETTENT CETTE DISTINCTION. 84. [fr.slideshare.net]
It was also confusion whether or not vesicular nucleus cell carcinoma was an independent variant of NPC. [jmio.org]
Workup
DIAGNOSTIC WORKUP A complete history and physical examination includes detailed evaluation of extent of disease in the pharynx ( Table 14-2 ). Extent of neck node metastases must be assessed, and a search made for distant metastases. [oncohemakey.com]
Workup includes: Careful visual examination (by mirror or endoscope), evaluation of neck nodes, evaluation of cranial nerve function and hearing. Skull X-rays (especially base-of-skull views) to evaluate neural foramina. CXR. [patient.info]
Treatment
Two patients died from the disease within three months of treatment with one patient surviving 36 months at the time of writing. One patient died from an unrelated medical condition three months after surgery. [ncbi.nlm.nih.gov]
Treatment innovations with molecularly targeted therapies and immunotherapy are being assessed to improve treatment outcomes in NPC and will impact oral complications and oral care. [scholars.northwestern.edu]
[…] down the treatment process. [saintpetershcs.com]
On the whole, the tolerance of the treatment was good (chemotherapy 71%, radiotherapy 82%). Treatment mortality was null. The BAC regime was the most effective. At the end of the treatment, a total response was obtained in 82% of cases. [ssl.elidee.com]
You will still receive the best standard treatment available. [macmillan.org.uk]
Prognosis
If you have nasopharyngeal cancer, you may have questions about your prognosis. A prognosis is the doctor’s best estimate of how cancer will affect someone and how it will respond to treatment. Prognosis and survival depend on many factors. [cancer.ca]
In order to support cancer therapy the dental provider must be aware of the diagnosis, prognosis and approach to treatment. [scholars.northwestern.edu]
As such, PD-1 and PD-L1 expression might correlate with poor prognosis in patients with nasopharyngeal carcinoma. [onclive.com]
Retropharyngeal lymph nodes [ edit ] It is not clear whether these are staged as N0 or N1, with differences among institutions Prognosis for RLN+ N0 appears comparable to N1 RLNs atrophy with age, and are usually obliterated by adulthood. [en.wikibooks.org]
The depth of infiltration is predictive of prognosis. T - Primary tumour Oropharynx: TX - primary tumour cannot be assessed. T0 - no evidence of primary tumour. Tis - pre-invasive cancer (carcinoma in situ). [patient.info]
Etiology
Etiology and general considerations of radiating implants are discussed. [semanticscholar.org]
Epidemiological and etiological factors associated with nasopharyngeal carcinoma. [npplweb.com]
To investigate genetic, dietary, occupational, and behavioral factors related to the etiology of NPC, several studies were conducted in including a case-control study of approximately 1,000 individuals and a multiplex family study of approximately 3,000 [grantome.com]
Etiology NPC is the commonest epithelial cancer in adults. [ojrd.biomedcentral.com]
Over several generations, the prevalence among Chinese-Americans gradually decreases to that among non-Chinese Americans, suggesting an environmental component to etiology. [merckmanuals.com]
Epidemiology
An epidemiologic and clinical study of nasopharyngeal carcinoma. International journal of radiation oncology, biology, physics. Mar-Apr 1978;4(3-4):182-198. [headandneckcancerguide.org]
Int J Cancer 85(3): 364–369 CrossRef PubMed Google Scholar Yu MC (1991) Nasopharyngeal carcinoma: epidemiology and dietary factors. [link.springer.com]
"The Enigmatic Epidemiology of Nasopharyngeal Carcinoma". Cancer Epidemiology, Biomarkers & Prevention. 15 (10): 1765–1777. doi : 10.1158/1055-9965.EPI-06-0353. PMID 17035381. ^ Li, Yvonne Y.; Chung, Grace T. Y.; Lui, Vivian W. [en.wikipedia.org]
Each entity is extensively discussed with information on clinicopathological, epidemiological, immunophenotypic and genetic aspects of these diseases. This book is in the series commonly referred to as the "Blue Book" series. Contributors: :Dr. [books.google.com]
Epidemiology Frequency United States Although the incidence varies according to geographic location, approximately 1 in every 100,000 children are diagnosed annually in North America. [emedicine.medscape.com]
Pathophysiology
Pathophysiology The detection of the Epstein-Barr virus (EBV) nuclear antigen and viral DNA in nasopharyngeal carcinoma has revealed that EBV can infect epithelial cells and is associated with their malignant transformation. [1] Copies of the EBV genome [emedicine.medscape.com]
Prevention
Causes, Risk Factors, and Prevention Learn about the risk factors for nasopharyngeal cancer and what you might be able to do to help lower your risk. Early Detection, Diagnosis, and Staging Know the signs and symptoms of nasopharyngeal cancer. [cancer.org]
Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. [headandneckcancerguide.org]
Prevention No sure way exists to prevent nasopharyngeal carcinoma. However, if you're concerned about your risk of nasopharyngeal carcinoma, you may consider avoiding habits that have been associated with the disease. [mayoclinic.org]
Tea tree oil : Tea tree oil is purported to have antiseptic properties, and has been used traditionally to prevent and treat infections. [livingnaturally.com]