Presentation
It is the purpose of this paper to present this case and to discuss some problems concerning genesis of symptoms of temporal arteritis. [ncbi.nlm.nih.gov]
Of these 12 at least 8 have presented with a similar symptomatology. Etiologic theories are discussed, and suggestions are made as to the possible management of infants presenting a similar diagnostic problem. Received November 3, 1958. [pediatrics.aappublications.org]
Disorders that present with pulmonary-renal syndrome, a combination of RPGN and DAH, include AAV, SLE, and Goodpasture's syndrome. RPGN is nearly always present in MPA, only rarely in EGPA, and sometimes in GPA. [clinicaladvisor.com]
Skin
- Skin Ulcer
Cutaneous: Livedo reticularis, skin ulcers, tender erythematous nodules, bullous or vesicular eruptions, infarction and gangrene of fingers or toes, or a combination may occur. [msdmanuals.com]
It can produce deep dermal ulcers, localized skin infarction, ischemia or necrosis of the fingertips, scleritis, and inflammation of multiple nerves (mononeuritis multiplex). vasculitis Widespread inflammation of blood vessels occurring as the principal [medical-dictionary.thefreedictionary.com]
Infections of chronic, deep skin ulcers have led to death from sepsis. Some investigators have postulated that HCV-related type II MC is a benign of low-grade B-cell lymphoproliferative disease. [lupusinternational.com]
Workup
Progress logically from the histologic pattern, through the appropriate workup, around the pitfalls, to the best diagnosis. [books.google.com]
DAH in conjunction with other manifestations of systemic vasculitis (see section below on common findings) should trigger a workup to establish a diagnosis. [clinicaladvisor.com]
X-Ray
- Cavitary Lesion
In contrast to GPA with its classic upper airway findings and cavitary lesions and EGPA with its asthma and ground glass opacities, MPA does not have features that distinguish it from other AAV aside from its very high rate of renal involvement. [clinicaladvisor.com]
Treatment
545 Dialysis ultrafiltration and hemofiltration 555 Use of drugs in uremia and dialysis 567 Donor and recipient selection in renal transplantation 587 Immunosuppression and treatment of rejection in renal transplantation 595 XIII 606 Renal tubular and [books.google.com]
However, it is sometimes difficult to set a boundary between severe cPAN and systemic PAN, and their optimal treatments are still unclear. [acrabstracts.org]
TREATMENT STUDIES Prompt treatment of interstitial keratitis with topical glucocorticoids usually prevents corneal scarring and vascularization. [lupusinternational.com]
Improved treatment has dramatically improved the survival but there is still significant morbidity from the disease (and/or its treatment). An understanding of the different types of vasculitis is helped by understanding classification. [lupusuk.org.uk]
Prognosis
The vasculitides represent a heterogenous set of disorders that differ in prognosis and response to therapy. [ncbi.nlm.nih.gov]
Prognosis is better if disease remission is achieved within 18 months after diagnosis. Relapses are less common than in other vasculitic disorders. [msdmanuals.com]
For example, a patient with purpura, nephritis, and abdominal pain caused by Henoch–Schönlein purpura usually has a good prognosis. .. [nejm.org]
What is the Prognosis of Necrotizing Vasculitis? (Outcomes/Resolutions) Outcomes for individuals with necrotizing vasculitis greatly vary depending on the location of inflammation and the severity of tissue damage. [dovemed.com]
Outlook (Prognosis) The outcome depends on the location of the vasculitis and the severity of tissue damage. [ufhealth.org]
Etiology
Etiologic theories are discussed, and suggestions are made as to the possible management of infants presenting a similar diagnostic problem. Received November 3, 1958. Accepted December 10, 1958. [pediatrics.aappublications.org]
Although the etiology is unclear, these clinical and epidemiological relations suggest that these patients form a distinct entity and that our concepts of necrotizing vasculitis should be broadened. FULL TEXT [annals.org]
These protean clinical manifestations, combined with the etiologic nonspecificity of the histologic lesions, complicate the diagnosis of specific forms of vasculitis. [nejm.org]
[…] vasculitides thought to represent hypersensitivity to an antigenic stimulus, such as a drug, infectious agent, or exogenous or endogenous protein; all disorders in this group involve the small vessels. nodular vasculitis a chronic vasculitis of unknown etiology [medical-dictionary.thefreedictionary.com]
Secondary pulmonary vasculitis can be associated with a number of diverse etiologies, including infection, drug reactions, connective tissue disease, and malignancy. [clinicaladvisor.com]
Epidemiology
Although the etiology is unclear, these clinical and epidemiological relations suggest that these patients form a distinct entity and that our concepts of necrotizing vasculitis should be broadened. FULL TEXT [annals.org]
An epidemiologic and histopathologic analysis. Arthritis Rheum 37: 1007-1012. Nordborg E, Bengtsson BA (1990) Epidemiology of biopsy-proven giant cell arteritis (GCA). J Intern Med 227: 233-236. [omicsonline.org]
Henoch-Schonlein purpura in children from northwestern Spain: a 20-year epidemiologic and clinical study. Medicine 2001;80(5):279-90. [ Links ] 40. Peru H, Soylemezoglu O, Bakkaloglu SA, et al. [scielo.org.mx]
"The epidemiology of the primary systemic vasculitides in northwest Spain: implications of the Chapel Hill Consensus Conference definitions". Arthritis Rheum. 49 (3): 388–93. doi : 10.1002/art.11115. PMID 12794795. ^ Churg J (September 1993). [en.wikipedia.org]
The INSERM Unit 169 of statistical and epidemiological studies: factors related to outcome in intensive care. French Multicenter Study. Crit Care 1989 ; 17 : 305 –8 7 Raffin T. Intensive care unit survival of patients with systemic illness. [academic.oup.com]
Pathophysiology
The differential diagnosis of the lesion is considered, and the pathophysiology of hypertension due to large vessel arteritis is discussed. [ncbi.nlm.nih.gov]
Suzuki H, Kiryluk K, Novak J et al (2011) The pathophysiology of IgA nephropathy. J Am Soc Nephrol 22(10):1795–1803 PubMedCentral PubMed CrossRef Google Scholar 25. [doi.org]
Behcet's syndrome pathophysiology and potential therapeutic targets. Intern Emerg Med. 2014;9:257–65. PubMed Google Scholar Arida A, Fragiadaki K, Giavri E, Sfikakis PP. [thrombosisjournal.biomedcentral.com]
Prevention
Furthermore it seems to be important to be aware of the specificity of focal arteritis in female genital tract as distinct from the generalized form to prevent unnecessary surgical or chemotherapeutical therapy for this lesion. [ncbi.nlm.nih.gov]
Collaborative Meta-Analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients. [books.google.es]
In cases of tissue infection, antibiotics are used How can Necrotizing Vasculitis be Prevented? Since little is known about the cause of necrotizing vasculitis, there are no known methods of preventing the condition. [dovemed.com]
Emergency symptoms include: Changes in pupil size Loss of function of an arm, leg, or other body part Speech problems Swallowing difficulty Weakness Severe abdominal pain Prevention There is no known way to prevent this disorder. [ufhealth.org]
N Engl J Med الصفحة 339 - Anderson JL, Muhlestein JB, Carlquist J, Allen A, Trehan S, Nielson C, Hall S, Brady J, Egger M, Hörne B, Lim T (1999) Randomized secondary prevention trial of azithromycin in patients with coronary artery disease and serological [books.google.com]