Symptomatic infection causes jaundice, lethargy, failure to thrive, abdominal distention, and clay-colored stools. Diagnosis is by serology. Rarely, severe illness may cause acute liver failure requiring liver transplantation. [msdmanuals.com]

By the age of 2 to 3 months, it becomes clear that an infant with neonatal hepatitis is not gaining weight and is growing at a slower than normal rate (failure to thrive). The infant may be irritable because of excessively itchy skin (pruritus). [rarediseases.org]

The younger brother developed jaundice and clay-colored stools at the age of 1 month. The diagnosis of extrahepatic biliary atresia was made at laparotomy at the age of 4 1/2 months. [ncbi.nlm.nih.gov]

Symptomatic infection causes jaundice, lethargy, failure to thrive, abdominal distention, and clay-colored stools. Diagnosis is by serology. Rarely, severe illness may cause acute liver failure requiring liver transplantation. [msdmanuals.com]

The observations on the critical evaluation of the neonatal jaundice cases led us to propose AIIMS clinical score (ACS) and this retrospective study was designed to evaluate the reliability of the ACS in all the 120 babies with jaundice referred to the [ncbi.nlm.nih.gov]

Infants with this condition are usually jaundiced. Jaundice that is caused by neonatal hepatitis is not the same as physiologic neonatal jaundice. [en.wikipedia.org]

Main Article Content Abstract It is known in this country that surgical obstructive jaundice cases used to be sent to the surgeon in the terminal state. [paediatricaindonesiana.org]

We present a case of severe HIDS in a young girl, whose symptoms started in the neonatal period with hepatomegaly, hepatitis, thrombocytopenia, and conjugated hyperbilirubinemia. [hindawi.com]

The hepatitis group had the highest frequencies of high-grade hepatomegaly and splenomegaly. Fifty six cases completely recovered. Two died of hepatic failure in early infancy and four had chronic liver diseases at the age of 12 months. [ncbi.nlm.nih.gov]

There was jaundice and hepatomegaly. Others systems were normal. [pediatriconcall.com]

[…] idiopathic • By mid-2000s, idiopathic neonatal hepatitis (INH) comprised only 15-30% of neonatal cholestasis due to increased ability to detect and diagnose metabolic and genetic disorders previously considered idiopathic Clinical Issues • Jaundice • Hepatomegaly [basicmedicalkey.com]

Jaundice that is caused by neonatal hepatitis is not the same as physiologic neonatal jaundice. In contrast with physiologic neonatal jaundice, infants with neonatal hepatitis present with dark urine. [en.wikipedia.org]

The observations on the critical evaluation of the neonatal jaundice cases led us to propose AIIMS clinical score (ACS) and this retrospective study was designed to evaluate the reliability of the ACS in all the 120 babies with jaundice referred to the [ncbi.nlm.nih.gov]

The detection of Au-Ag in prolonged neonatal jaundice with direct bilirubinemia favors a diagnosis of hepatitis type B, which in our experience carries a graver prognosis reflected in deaths and cirrhosis when compared to neonatal hepatitis not associated [pediatrics.aappublications.org]

At 30 hours of life, the infant was noted to have scleral icterus. Total and direct bilirubin was 26.6 and 15.1 mg/dl, respectively, and on repeat were 25.5 and 14.5 mg/dl. [nature.com]

CLINICAL PRESENTATIONCLINICAL PRESENTATION Jaundice Scleral icterus Hepatomegaly Acholic stools Dark urine Other signs and symptoms depend on specific disease process 18. [slideshare.net]

icterus, acholic stools, dark yellow urine, and hepatomegaly. [ncbi.nlm.nih.gov]

Paediatricians need to look for additional clinical signs, such as ichthyosis, hypertrichosis, cutis laxa, skeletal changes, or congenital deafness, which could point to new conditions emerging in the spectrum of prolonged neonatal cholestasis. [journals.lww.com]

Paediatricians need to look for additional clinical signs, such as ichthyosis, hypertrichosis, cutis laxa, skeletal changes, or congenital deafness, which could point to new conditions emerging in the spectrum of prolonged neonatal cholestasis. [journals.lww.com]

Serum C-reactive protein increased to 33.9 mg/L. [ncbi.nlm.nih.gov]

Transferrin receptor co-localizes and interacts with the hemochromatosis factor (HFE) and the divalent metal transporter-1 (DMT1) in trophoblast cells. J Cell Physiol. 2005; 204 901-912 10 Nicolas G, Bennoun M, Devaux I et al.. [doi.org]