However, controversy remains surrounding its definition and management especially in asymptomatic patients. [ncbi.nlm.nih.gov]

Asymptomatic hypoglycemic (blood glucose level Results: Dextrose gel with feeds increased the blood glucose level in 184/250 (74%) of asymptomatic hypoglycemic infants compared to 144/248 (58%) with feeds only (p 0.01). [karger.com]

The level of blood glucose at which treatment is recommended in asymptomatic babies is unclear. Blood glucose levels as low as 30 mg/dL in the first 1–2 hours after birth in asymptomatic babies may not be harmful. [babygooroo.com]

Hypothermia 5. Hyperviscosity 6. Erythroblastosis fetalis, fetal hydrops 7. Other a. Iatrogenic causes b. Congenital cardiac malformations C. Intrauterine growth restriction D. Hyperinsulinism E. Endocrine disorders F. [aafp.org]

Factors which increase the risk of hypoglycemia • Various factors which increase the risk of hypoglycemia are hypothermia & cold Stress, cold environment, wet baby and inadequate feeding. 6. [slideshare.net]

Neuroglycopenic signs include seizure, coma, cyanotic episodes, apnea, bradycardia or respiratory distress, and hypothermia. Listlessness, poor feeding, hypotonia, and tachypnea may occur. [msdmanuals.com]

Symptoms Jittery or Tremors Lethargic Hypotonia Apnea Hypothermia Cyanosis Seizures Weak or high pitched cry Poor feeding V. [fpnotebook.com]

A 6-day old term infant born to a non-diabetic mother was admitted to our hospital with, seizures, irritability and poor feeding. The infant's Apgar score was 8 at 1 minute and 9 at 5 minutes and weighed 3100 g. [ijri.org]

Difficulty breathing or pauses in breathing (apnea) Rapid breathing Problems regulating body temperature Decreased muscle tone, medically referred to as hypotonia Irritability Grunting Fatigue Listlessness Nausea Skin paleness Vomiting Poor feeding Sweating [thecplawyer.com]

[…] pale skin Breathing problems, such as rapid breathing (tachypnea), pauses in breathing (apnea), or a grunting sound Irritability or listlessness Loose or floppy muscles (hypotonia) Vomiting or poor feeding Weak or high pitched cry Tremors, shakiness, sweating [abclawcenters.com]

Other symptoms may be dizziness, tremulousness, sweating, and insomnia. [kmle.co.kr]

[…] associated with the hypoglycemic neonates were, refusal of feeding (45%), hyporeflexia (36.2%), irritability (30%), cyanosis (28.4%), tackypnea (24.5%), seizure (16.6%), weak cry (15.8%), apneic spels (9.8%), pallor (1.9%), cardiac arrest (9.1%) and sweating [pjms.com.pk]

Bluish-colored or pale skin Breathing problems, such as pauses in breathing (apnea), rapid breathing, or a grunting sound Irritability or listlessness Loose or floppy muscles Poor feeding or vomiting Problems keeping the body warm Tremors, shakiness, sweating [medlineplus.gov]

Ictal manifestations of main seizures were identical to occipital lobe seizures, such as eye deviation, eye blinking, ictal vomiting, and visual hallucination. [ncbi.nlm.nih.gov]

Adrenergic signs include diaphoresis, tachycardia, lethargy or weakness, and shakiness. Neuroglycopenic signs include seizure, coma, cyanotic episodes, apnea, bradycardia or respiratory distress, and hypothermia. [msdmanuals.com]

View/Print Table TABLE 1 Clinical Signs Associated with Hypoglycemia* Changes in levels of consciousness Irritability Lethargy Stupor Apnea, cyanotic spells Coma Feeding poorly after feeding well Hypothermia Hypotonia, limpness Tremor Seizures TABLE 1 [aafp.org]

The most common clinical manifestations can include altered level of consciousness, seizure, vomiting, unresponsiveness, and lethargy. [emedicine.medscape.com]

Some infants will display no obvious symptoms, while others will exhibit lethargy, apnea, a bluish hue to the skin, low body temperatures, jitters, and in severe cases, seizures. [thurswell.com]

Nine children with neonatal seizures had moderate or severe white matter injury and 7 had cortical involvement. At 18-month follow-up of 34 children, outcome was normal in 8, showed mild impairment in 15, moderate in 8, and severe impairment in 3. [pediatricneurologybriefs.com]

seizures -- Intraventricular hemorrhage -- Surgical emergencies in the newborn -- Necrotizing enterocolitis. [worldcat.org]

Figures and Tables - Analysis 1.5 Comparison 1 Dextrose gel versus control, Outcome 5 Neonatal seizures. Figures and Tables - Analysis 1.6 Comparison 1 Dextrose gel versus control, Outcome 6 Exclusive breast feeding after discharge (WHO definition). [cochranelibrary.com]

Neonatal seizure s ‐ No seizures occurred in the dextrose gel or placebo group in the one study that reported this outcome (one study, 237 infants). Therefore, the odds ratio is not estimable. [doi.org]

“In approximate order of frequency there are jitteriness or tremors, apathy, episodes of cyanosis, convulsions, intermittent apneic spells or tachypnea, weak or high-pitched cry, limpness or lethargy, difficulty in feeding, and eye rolling. [cps.ca]

[…] judgment Nonspecific dysphoria, moodiness, depression, crying, exaggerated concerns Feeling of numbness, pins and needles (paresthesia) Negativism, irritability, belligerence, combativeness, rage Personality change, emotional lability Fatigue, weakness, apathy [en.wikipedia.org]

Other neurologic problems included developmental delays, learning and behavior problems, hyperactivity and attention difficulties, autistic features, microcephaly and cortical blindness. [ncbi.nlm.nih.gov]

This glycolytic pathway along with free fatty acids increases adenosine triphosphate (ATP) production within the β-cell. KATP channels consist of two subunits, the sulfonylurea (SUR) and the inward rectifier potassium channel (Kir6.2) subunits. [ncbi.nlm.nih.gov]

In addition, the incidence of neurodevelopmental delay was 44%.51 Adverse outcomes are presumed to be caused by hypoketotic hypoglycemia, but there may be other genetic abnormalities affecting neurodevelopment in this patient population as yet unidentified [ncbi.nlm.nih.gov]

Activating mutations of glucokinase (GCK) ( Fig. 1 ), the “glucose sensor” of the β-cell, are rare and, depending on the mutation, may cause fasting hypoglycemia in varying degrees at varying ages of life ( 8 ). [diabetes.diabetesjournals.org]

Protein-sensitive and fasting hypoglycemia in children with the hyperinsulinism/hyperammonemia syndrome. J Pediatr. 2001;138:383–9. PubMed CrossRef Google Scholar 16. Bahi-Buisson N, Roze E, Dionisi C, Escande F, Valayannopoulos V, Feillet F, et al. [link.springer.com]

HI Patients with this disorder present post-prandial and fasting hypoglycemia and permanent hyperammoniemia, neurological signs and epilepsy occur later in infancy and are not consequences of recurrent hypoglycemia [17]. [latunisiemedicale.com]