General Presentation Children frequently present at the physician’s office or emergency room with a fever and rash. [learn.pediatrics.ubc.ca]

Sexual abuse may present with rectal bleeding. A high index of suspicion in the clinician will be alerted by unusual features in the history or examination. [patient.info]

Primarily extraintestinal presentation : About 10% of children with IBD present with extracolonic symptoms. The most common is growth failure. [medicalhomeportal.org]

Symptoms present at birth, and continuous. [102] Symptoms may be present at birth or early infancy. [102] Purpuric rash presenting at birth or in infancy. Vasculitis noted on skin biopsy. [autoinflammatory-search.org]

Objective/s This article examines neonatal dermatoses according to various clinical presentations. [racgp.org.au]

• Infectious Mononucleosis

  Mononucleosis, Susceptibility To Lymphoproliferative Disease, X-Linked Lymphoproliferative Syndrome, X-Linked Lyp Purtilo Syndrome Xlp XLP1 EBVS IMD5 XLPD 308240 Genetic Test Registry Lymphoproliferative Syndrome, X-Linked, 2 XIAP Deficiency XLP2 300635 [ukgtn.nhs.uk]

• Papule

  flat lesion ( – Papule: palpable, elevated lesion ( – Maculopapular: combination of macular and popular lesions – Purpura: non-blanching papules or macules due to extravasation of RBCs – Vesicle: fluid-filled, elevated skin lesion ( – Bulla: fluid-filled [learn.pediatrics.ubc.ca]

  Urticating and blistering papules and plaques in urticaria pigmentosa (a form of mastocytosis) Figure 9. [racgp.org.au]

  Clinical presentation: Benign vascular tumor, appears as small bright red papule that grows over several weeks to months into sessile or pedunculated papule with a “collarette” or scale. Usually no bigger than 1 cm. [unboundmedicine.com]

  Ulcers usually initially look like small bug bites or papules, and they progress to larger ulcers. Though the wounds rarely lead to death, they can cause pain and scarring. [en.wikipedia.org]

  It is characterized by small keratotic follicular papules forming disseminated salmon-colored scaly plaques that surround islands of normal skin, and diffuse red-orange palmoplantar keratoderma. Lesions typically progress rostral to caudal. [ojrd.biomedcentral.com]

Laboratory Testing Exclusion of infectious etiology is the first step in the workup. Infection should be reliably excluded before embarking on a more costly workup and initiation of immunosuppressant medications. [medicalhomeportal.org]

Study backs wider use of fecal calprotectin in pediatric IBD workup. Medscape Medical News by WebMD. May 27, 2013. Available at http://www.medscape.com/viewarticle/804796. Accessed: June 1, 2013. Henderson P, Anderson NH, Wilson DC. [emedicine.medscape.com]

Treatment may include: Lifestyle and Medical Treatment Drug therapy Diet Supplements Feeding through a vein Learn more about medical treatment for Crohn’s disease. [brighamandwomens.org]

They'll help draw up a specific treatment plan for you. [nhs.uk]

Treatment of collagenous colitis and lymphocytic colitis There is no cure, but treatment can manage the symptoms. [betterhealth.vic.gov.au]

Treatment Phototherapy, pictured here, is a treatment for cases of infant jaundice that do not resolve on their own. Typically, treatment for mild jaundice in infants is unnecessary, as it tends to disappear on its own within 2 weeks. [medicalnewstoday.com]

Many patients respond differently to different types of treatment, for example some benefit from a moist environment, so treatment should be carefully evaluated at each stage. [en.wikipedia.org]

NSCLC is often diagnosed at an advanced stage and has a poor prognosis. {ECO:0000269 PubMed:15118125, ECO:0000269 PubMed:16533793, ECO:0000269 PubMed:16672372}. Note=The gene represented in this entry is involved in disease pathogenesis. [genecards.org]

Reduction in the amount of soy-based intravenous lipid solutions or use of fish oil based lipid emulsions appears to significantly improve the prognosis. [rarediseases.org]

What is the prognosis for a person with colitis? Patients with infectious diarrhea tend to get better relatively quickly with supportive care. Most infections will resolve with or without specific treatment and often do not require antibiotics. [medicinenet.com]

As the prognosis is so severe, prenatal diagnosis can be discussed. [ojrd.biomedcentral.com]

[…] a good prognostic indicator in patients with sarcoidosis, although this may be true only for patients of northern European descent. 3 Sarcoidosis with hilar adenopathy, polyarthritis, and erythema nodosum is called Löfgren's syndrome and has a good prognosis [aafp.org]

Nursing Interventions Rationale Ascertain onset and pattern of diarrhea To assess etiology. Chronic diarrhea (caused by irritable bowel syndrome, infectious diseases affecting colon such as IBD). [nurseslabs.com]

Certain drugs, including oral contraceptives and some antibiotics, also may be etiologic. [aafp.org]

Although the differential diagnosis is very broad, adequate history and physical examination can help the clinician narrow down a list of more probable etiologies. [learn.pediatrics.ubc.ca]

Etiology and pathophysiology 2.1. [intechopen.com]

[…] microdeletion Alagille syndrome due to a JAG1 point mutation Tetralogy of Fallot Synonym(s): (no synonyms) Classification (Orphanet): - Rare gastroenterologic disease - Rare genetic disease - Rare skin disease Classification (ICD10): (no data available) Epidemiological [csbg.cnb.csic.es]

Meyer EA (1985) The epidemiology of giardiasis. Parasitology Today 1:101–105 PubMed CrossRef Google Scholar 76. [link.springer.com]

Epidemiology The incidence and prevalence of rectal bleeding in children are poorly documented. Certain causes such as anal fissure are common in general practice. Overall it is not a common presentation in children attending hospital. [patient.info]

Clinical presentation/epidemiology: Summarized by the SCRATCH principles. 15 S ymmetric eruption: Exposed areas and scalp commonly affected. Spares diaper region, palms, and soles. [unboundmedicine.com]

However, very little information has been assembled regarding the phenotype, genetics and epidemiology of the more recently discovered autoinflammatory disorders. [ojrd.biomedcentral.com]

Researchers Inc Tom Grill/Age Fotostock Luca Trovato/The Image Bank iStock Pixland Arthur Tilley/Taxi Gunter Lenz/Imagebroker RF Lester Leftowitz/Stone Tim Platt/Iconica Moment/Cultura REFERENCES: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: "Pathophysiology [onhealth.com]

Pathophysiology (4th ed). St. Louis, MO: Elsevier. 3. Paddock, C. (2011). Is Type 2 diabetes an autoimmune disease? 4. Crohn’s and Colitis Foundation of America. (2013). What are Crohn’s and Colitis? 5. Houtchens, M. (2013). [breastfeedingusa.org]

Pathophysiology and Histopathology Erythema nodosum is a nonspecific cutaneous reaction pattern to a variety of antigens, with many immune-mediated mechanisms implicated. [aafp.org]

Etiology and pathophysiology 2.1. [intechopen.com]

Pathophysiology of inflammatory bowel disease: an overview. Surg Clin North Am. 2007 Jun. 87(3):575-85. [Medline]. Rioux JD, Xavier RJ, Taylor KD, et al. [emedicine.medscape.com]

The goal of treatment is to relieve symptoms, prevent other problems, and prevent future flare-ups. [kidshealth.org]

Gradual resumption of liquids may prevent cramping and recurrence of diarrhea; however, cold fluids can increase intestinal motility. Provide opportunity to vent frustrations related to disease process. [nurseslabs.com]

[…] about treating migraine and preventing migraine. [nhs.uk]

Prevention The best way of reduce chances of an infant developing jaundice is to make sure they are well fed. [medicalnewstoday.com]

Postoperative medical therapy often prevents recurrence, although data are lacking regarding efficacy. [emedicine.medscape.com]