Presentation
Erythroderma is a common presentation. Some babies may present as " collodion " babies. Syndromes (e.g. [adhb.govt.nz]
Weiner, Bernard Gonik, Caroline Crowther, and Stephen Robson present an evidence-based approach to the available management options, equipping you with the most appropriate strategy for each patient. [books.google.com]
The most common presentations of MS include optic neuritis, transverse myelitis, arm-leg weakness, sensory disturbances, or balance problems. [umg.rwjms.rutgers.edu]
Among complications beyond the neonatal period, 8 (20.5%) children developed asthma, one presented negative ANA oligoarthritis and another presented immune thrombocytopenic purpura. [reumatologiaclinica.org]
Entire Body System
- Hypothermia
F Nayeri F Nili Keywords: Hypothermia, Abstract Hypothermia is one of the main causes of neonatal mortality in developing countries. [ijph.tums.ac.ir]
Hypothermia is a core temperature 36 to 36.5° C. In premature infants, hypothermia increases morbidity and mortality. Hypothermia may be purely environmental or represent intercurrent illness (eg, sepsis). [msdmanuals.com]
One such multi-country trial–‘HELIX’ (Hypothermia for Encephalopathy in Low Income countries) is currently being set up [35]. [journals.plos.org]
ICD-10-CM GUIDELINES • Hypothermia of newborn- P80 • Other disturbances of temperature regulation of newborn- P81 • Other conditions of integument specific to newborn- P83 • https://www.medesunglobal.com 9. THANK YOU [slideshare.net]
[…] of newborn P80.0 Cold injury syndrome P80.8 Other hypothermia of newborn P80.9 Hypothermia of newborn, unspecified P81 Other disturbances of temperature regulation of newborn P81.0 Environmental hyperthermia of newborn P81.8 Other specified disturbances [icd10data.com]
- Anemia
[…] panniculitis Majeed syndrome Maple syrup urine disease Marfan syndrome Mastocytosis Mitochondrial disease Mixed autoinflammatory and autoimmune syndrome Mixed connective tissue disease Neonatal antiphospholipid syndrome Neonatal autoimmune hemolytic anemia [se-atlas.de]
New chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors keep you current on the late preterm infant, the fetal origins of adult disease, neonatal anemia, genetic disorders, and more. "...a valuable reference [books.google.com]
[…] complicating pregnancy, first trimester O99.012 Anemia complicating pregnancy, second trimester O99.013 Anemia complicating pregnancy, third trimester O99.019 Anemia complicating pregnancy, unspecified trimester O99.02 Anemia complicating childbirth [app.drchrono.com]
The tests are organized into broad categories: Metabolic disorders (e.g., phenylketonuria, PKU) Endocrine disorders (e.g., congenital hypothyroidism [CH] and congenital adrenal hyperplasia [CAH ]) Hemoglobin disorders (e.g., sickle cell anemia ) Other [labtestsonline.org]
Read Next: Sickle Cell Anemia + 5 Natural Treatments to Manage Symptoms From the sound of it, you might think leaky gut only affects the digestive system, but in reality it can affect more. [draxe.com]
- Weight Loss
It generally begins with vague symptoms like weakness, joint pain, weight loss, fatigue and/or rashes. After a few months, more serious symptoms may set in. ISN. Personal Stories Lupus Personal Stories. [sclero.org]
Research shows that optimal breast-feeding practices, which result in minimal initial weight loss and early onset of weight gain, are associated with reduced breastfeeding jaundice. ( 9 ) Poor Weight Recovery Research has found that newborns born at very [draxe.com]
(11) Bottle feeding (1) Childhood obesity (44) Dehydration (2) Diabetic diet (6) Diet (72) Diet and cancer (3) Food labeling (3) Malnutrition (3) Minerals (1) Nutrition (122) Obesity (97) Overweight (53) Parenteral nutrition, total (2) Vitamins (2) Weight [innovations.ahrq.gov]
Other: facial pain due to trigeminal neuralgia, hand paresthesias, headache, stroke, fatigue, calcinosis and weight loss. [en.wikipedia.org]
- Pallor
Some lesions had a target appearance with central pallor surrounded by an erythematous border. Others coalesced into large patches. Subsequently, the baby's mother was diagnosed with an autoimmune disorder, probably Systemic Lupus Erythematosis. [adhb.govt.nz]
Severe RDS or those inadequately treated may develop: Hypotension Cyanosis Pallor increase Grunting decrease or disappear Mixed respiratory-metabolic acidosis Apnea and irregular respirations which indicate fatigability Complications of neonatal respiratory [lecturio.com]
- Candidiasis
[…] tetanus neonatorum (A33) P37.0 Congenital tuberculosis P37.1 Congenital toxoplasmosis Hydrocephalus due to congenital toxoplasmosis P37.2 Neonatal (disseminated) listeriosis P37.3 Congenital falciparum malaria P37.4 Other congenital malaria P37.5 Neonatal candidiasis [embryology.med.unsw.edu.au]
[…] unspecified P37.0 Congenital tuberculosis P37.1 Congenital toxoplasmosis Includes: Hydrocephalus due to congenital toxoplasmosis P37.2 Neonatal (disseminated) listeriosis P37.3 Congenital falciparum malaria P37.4 Other congenital malaria P37.5 Neonatal candidiasis [app.drchrono.com]
Gastrointestinal
- Abdominal Pain
pain (1) Abdominal pain, chronic (1) Celiac disease (1) Crohn's disease (1) Cystic fibrosis (3) Digestive system disorders (1) Digital rectal examination (3) Functional gastrointestinal disorders (1) Gastroesophageal reflux disease (2) Gastrointestinal [innovations.ahrq.gov]
Other symptoms in adults vary, but individuals may experience: Abdominal pain Fever Arthritis Headache Weight loss Swelling in legs or abdomen Rectal bleeding Nausea, vomiting and diarrhea Pale-colored stools Dark-colored urine Weakness ( 6 ) Jaundice [draxe.com]
Cardiovascular
- Hypertension
The possibility that neonatal pulmonary hypertension represents an isolated autoimmune disease or a hitherto undescribed neonatal syndrome is proposed and the immunogenetic autoantibody implications are discussed. [ncbi.nlm.nih.gov]
Hypertensive response to TRH testing in scleroderma. Arthritis and Rheum. S4:24, 1982. Whitman HH. At al. Variable Response to oral converting enzyme inhibitor in hypertensive scleroderma patients. [hss.edu]
Neonatal Scleroderma Anatomical Context for Neonatal Scleroderma MalaCards organs/tissues related to Neonatal Scleroderma: 42 Bone Publications for Neonatal Scleroderma Articles related to Neonatal Scleroderma: # Title Authors Year 1 Isolated pulmonary hypertension [malacards.org]
Systemic scleroderma can manifest itself in pulmonary fibrosis, raynaud's syndrome, digestive system telangiectasias, renal hypertension and/or pulmonary hypertension. A chronic multi-system disorder of connective tissue. [icd10data.com]
Apply new evidence-based management options to treat genetic and constitutional factors leading to a high-risk pregnancy (such as diabetes, obesity, hypertension, and cardiac disease) through new and expanded coverage of these increasingly common presentations [books.google.com]
- Vascular Disease
Includes: autoimmune disease NOS collagen (vascular) disease NOS systemic autoimmune disease systemic collagen (vascular) disease Excludes1 autoimmune disease, single organ or single cell-type -code to relevant condition category M34 Systemic sclerosis [icd10coded.com]
[…] from the GAD Gene-Disease Associations dataset. peripheral vascular diseases; systemic scleroderma Gene Set From GAD Gene-Disease Associations genes associated with the disease peripheral vascular diseases; systemic scleroderma in GWAS and other genetic [amp.pharm.mssm.edu]
Hemodynamic effects of captopril in pulmonary hypertension of collagen vascular disease. Am Heart J. 104:834-8, 1982 Whitman HH, Case DB. New Developments in the treatment of scleroderma. [hss.edu]
NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases Collagen vascular disease (Medical Encyclopedia) Scleroderma (Medical Encyclopedia) Swallowing problems (Medical Encyclopedia) [ Read More ] Systemic scleroderma Systemic scleroderma [icdlist.com]
Liver, Gall & Pancreas
- Jaundice
Jaundice Causes Neonatal (Newborn Jaundice) Jaundice is common among newborns because the metabolism, circulation and excretion of bilirubin are slower than in adults. [draxe.com]
[…] the GAD Gene-Disease Associations dataset. jaundice, neonatal; neonatal jaundice Gene Set From GAD Gene-Disease Associations genes associated with the disease jaundice, neonatal; neonatal jaundice in GWAS and other genetic association datasets from the [amp.pharm.mssm.edu]
A significant relationship was found between hypothermia and respiratory distress in the first six hours of birth and death, as well as with jaundice, hypoglycemia and metabolic acidosis in the first three days of birth (P=0.0001). [ijph.tums.ac.ir]
[…] due to other excessive haemolysis Excl.: jaundice due to isoimmunization (P55-P57) P58.0 Neonatal jaundice due to bruising P58.1 Neonatal jaundice due to bleeding P58.2 Neonatal jaundice due to infection P58.3 Neonatal jaundice due to polycythaemia P58.4 [embryology.med.unsw.edu.au]
[…] due to bruising P58.1 Neonatal jaundice due to bleeding P58.2 Neonatal jaundice due to infection P58.3 Neonatal jaundice due to polycythemia P58.41 Neonatal jaundice due to drugs or toxins transmitted from mother P58.42 Neonatal jaundice due to drugs [app.drchrono.com]
Skin
- Skin Rash
It consists of red scaly skin lesions and resembles the rash with SLE. It appears that newborn girls are slightly more susceptible to the skin rash. The rash is not permanent, but in some rare cases skin lesions may persist into childhood. [mollysfund.org]
Anti-Ro activity is also found in approximately 40 percent of patients with systemic lupus erythematosus and is associated with photosensitive skin rash, pulmonary disease and lymphopenia. 13 Anti-La activity is detected in 10 to 15 percent of patients [aafp.org]
[…] and soft-tissue care (37) Burn injury (2) Decubitus ulcer (23) Diabetic foot (5) Psoriasis (1) Skin rash (1) Sun exposure (3) Wound care (3) ► Substance abuse (177) Alcohol abuse (39) Alcohol and/or drug screening (10) Alcohol consumption (19) Alcohol [innovations.ahrq.gov]
- Yellow Discoloration of the Skin
[…] cries Adult Adults with jaundice will have a yellow discoloration of the skin and may also have yellowing of the whites of the eyes or mucous membranes. [draxe.com]
Musculoskeletal
- Arthritis
A self-help guide for youth, Juvenile Arthritis: The Ultimate Teen Guide is also useful to family members, friends, and caregivers of those suffering from the disease. [books.google.com]
[…] purpura, HCV-associated arthritis, HIV-associated rheumatic disease syndrome, Raynaud’s phenomenon, fungal arthritis, hypermobility syndrome, polymyositis, infectious arthritis, juvenile arthritis, juvenile dermatomyositis, juvenile spondylarthropathy [reumed.ro]
Prospective study of cell-free fetal DNA and disease activity during pregnancy in women with inflammatory arthritis. Arthritis Rheum 54:2069-73, 2006. Adams KA, Nelson JL. [gs.washington.edu]
The skin lesions in a large number of the 100 or so diseases that cause arthritis are treated differently. [uihc.org]
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31:315–24. 5. Shmerling RH. Rheumatic disease: choosing the most useful diagnostic tests. [aafp.org]
Psychiatrical
- Withdrawn
Results Thirty three neonates were entered into the study but 10 were withdrawn from analysis: four had not met the entry criteria as they received feeds on the tenth postoperative day; five patients completed the seven days of treatment but were subsequently [fn.bmj.com]
Neurologic
- Seizure
It is a highly individualized disease; involvement may range from mild symptoms to life threatening. seizure disorder A chronic medical condition produced by temporary changes in the electrical function of the brain, causing seizures which affect awareness [michigan.gov]
You should seek immediate emergency care for your child if you observe more serious symptoms like shortness of breath, heart problems, and seizures. [intermountainhealthcare.org]
Workup
Sclerodera Workup. Medscape. Available online at http://emedicine.medscape.com/article/331864-workup. Accessed September 2013. Scleroderma: An Overview. Cleveland Clinic. [labtestsonline.it]
If the cause is unclear, the individual receives a laboratory workup that measures blood counts and tests for liver function and infectious hepatitis. [draxe.com]
"Scleroderma Workup". Medscape Reference. WebMD. Archived from the original on 6 March 2014. Retrieved 6 March 2014. ^ a b c d e f g Jimenez, SA; Cronin, PM; Koenig, AS; O'Brien, MS; Castro, SV (15 February 2012). [en.wikipedia.org]
Treatment
Make informed clinical choices for each patient, from diagnosis and treatment selection through post-treatment strategies and management of complications, with new evidence-based criteria throughout. [books.google.com]
Symptoms and Complications Treatments for Lupus Treatments for Lupus. [sclero.org]
Stool was passed on 6.3 (SEM 0.4) treatment days in the cisapride subgroup compared with 4.1 (SEM 1.0) treatment days in the placebo subgroup. [fn.bmj.com]
[ edit ] Main treatment [ edit ] There is no definitive cure for LS. [22] Behavior change is part of treatment. [en.wikipedia.org]
Prognosis
The prognosis is poor if it becomes generalized. [medical-dictionary.thefreedictionary.com]
With the proper support and medical care, most children with scleroderma can expect a good prognosis and a normal lifespan. Scleroderma [skleer-uh-DUR-muh], which means “hard skin,” is a chronic disease that occurs rarely in children. [intermountainhealthcare.org]
Although permanent, the long-term prognosis for children with heart block is good. And for those babies who only have skin issues of neonatal lupus, the long-term prognosis is excellent. [mollysfund.org]
Diagnosing monogenic autoimmunity is crucial for patients’ prognosis and clinical management. [diabetes.diabetesjournals.org]
Prognosis is poor. • Minimal inflammation helps distinguish sclerema neonaturum from subcutaneous fat necrosis of the newborn. 4. [slideshare.net]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Etiology and Pathophysiology of IRDS Discussing the normal lung development is important to understand the pathophysiology of neonatal respiratory distress syndrome. [lecturio.com]
X-ray diffraction techniques have confirmed that infants with sclerema neonatorum have an increase in saturated fats and that the crystals within the fat cells are composed of triglycerides. [3, 4] Etiology Associated underlying conditions include pneumonia [emedicine.medscape.com]
Epidemiology
"Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers". Current Opinion in Rheumatology. 24 (2): 165–70. doi : 10.1097/BOR.0b013e32834ff2e8. [en.wikipedia.org]
[…] syndrome, congenital heart defects, gastroenteritis, intestinal obstruction, and severe malnutrition. [2, 5, 6, 7] Two case reports have described sclerema neonatorum that developed after therapeutic hypothermia initiated for neonatal asphyxia. [8, 9] Epidemiology [emedicine.medscape.com]
Pathophysiology
The pathophysiologic basis for the development of neonatal autoimmunity is not entirely clear, but differences in the neonatal immune system compared with the adult immune system, as well as unique characteristics of target antigens in the newborn period [ncbi.nlm.nih.gov]
Muckle-Wells syndrome, which all share a common pathophysiologic mechanism. [widodojudarwanto.wordpress.com]
Springer-Verlag 1991 Pathogenesis of vitamin K deficiency in newborn infants (In : Vitamins and Biofactors in Life Science) Center for Academic Publications Japan 1992 Research Grants & Projects Study on Pathogenesis of Vitamin K Deficiency Study on Pathophysiology [researchmap.jp]
Etiology and Pathophysiology of IRDS Discussing the normal lung development is important to understand the pathophysiology of neonatal respiratory distress syndrome. [lecturio.com]
Endothelin signalling is implicated in the pathophysiology of fibrosis. [22] Vitamin D is implicated in the pathophysiology of the disease. [en.wikipedia.org]
Prevention
You can also find out more about preventive medicine and the steps you can take to keep you and your family healthy by reading the companion article Wellness and Prevention in an Era of Patient Responsibility. [labtestsonline.org]
Maintaining an appropriate environmental temperature is the most important step in preventing hypothermia in neonates. [msdmanuals.com]
Succinct, targeted coverage of normal childhood growth and development, as well as the diagnosis, management, and prevention of common pediatric diseases and disorders, make this an ideal medical reference book for students, pediatric residents, nurse [books.google.com]
[…] care processes (977) Fall prevention (46) Immunizations (98) Prenatal care (68) Primary prevention (596) Secondary prevention (425) Tertiary prevention (10) ► Patient Population ► Age (662) Adolescent (13-18 years) (260) Adult (19-44 years) (77) Aged [innovations.ahrq.gov]
Management of IRDS Prevention of neonatal respiratory distress syndrome As the respiratory distress syndrome is a disease of prematurity, the most effective preventive method is to avoid the pre-term labor. [lecturio.com]