This is the first report of a female neonate presenting with hyponatremia due to NSIAD. [ncbi.nlm.nih.gov]

Neurologic workup was consistent with acute motor and sensory axonal neuropathy (AMSAN), a variant of Guillain-Barre syndrome. Concomitantly on admission, serum chemistry panel showed a sodium (Na) 115 mmol/L with normal kidney function. [pulmonarychronicles.com]

20-150 IU/L Uric Acid 4.6 mg/dl 2.5-5.5 mg/dl TSH 4.1 ng/dl 3-18 ng/dl T4 1.4 ng/dl 0.8-2.4 ng/dl ACTH 25-100pg/ml Renin 3.26 ng/ml/hr 2.9-24 ng/ml/hr Aldosterone 33.9 ng/dl 1-160 ng/dl Table 1: The pertinent laboratories values Special studies for workup [omicsonline.org]

[…] resonance imaging of the head (for detection of cerebral edema occurring as a complication of SIADH, for identification of a CNS disorder responsible for SIADH, or for helping to rule out other potential causes of a change in neurologic status) See Workup [emedicine.medscape.com]

An effective treatment of NSIAD is available. It consists of fluid restriction and administration of oral urea. Reported experience with furosemide treatment in NSIAD is still lacking. [ncbi.nlm.nih.gov]

In fact, the treatment choice for SIAD depends on Uosm. [myslide.es]

Management and treatment Treatment of NSIAD is lifelong. Fluid restriction is the cornerstone of treatment. It is generally sufficient to avoid episodes of hyponatremia and is well tolerated (good compliance). [orpha.net]

The constitutive signalling of R137C/L-V2R was not inhibited by treatment with the V2R inverse agonist SR121463. [molpharm.aspetjournals.org]

Prognosis The prognosis of NSAID is good, if episodes of severe hyponatremia are avoided. The documents contained in this web site are presented for information purposes only. [orpha.net]

Outlook (Prognosis) If a person drinks enough water, this condition will not have much effect on the fluid or electrolyte balance of the body. Sometimes, passing a lot of urine for a long time can cause other electrolyte problems. [umms.org]

Women appear to be more prone to drug-induced hyponatremia and to exercise-induced hyponatremia (marathon runners), although this may be an association with low body weight rather than sex. [5] Prognosis The prognosis of SIADH correlates with the underlying [emedicine.medscape.com]

We have elaborated two complementary strategies to treat SIADH-induced hyponatremia in an attempt to increase awareness of its importance, simplify its therapy, and improve prognosis. [revistanefrologia.com]

Etiology NSIAD is due to a gain of function mutation in the type 2 AVP receptor ( AVPR2 ) gene (location Xq28), thus representing the mirror image of nephrogenic diabetes insipidus (see this term). [orpha.net]

"[Etiology, diagnostics and therapy of hyponatremias]". Orv Hetil. 149 (29): 1347–54. doi : 10.1556/OH.2008.28409. PMID 18617466. Clayton, JA.; Le Jeune, IR.; Hall, IP. (2006). [wikidoc.org]

Volume depletion caused by diuretic induces ADH secretion. [4] Etiology central nervous system disorders [5] meningitis, encephalitis brain abscess CNS infections subarachnoid hemorrhage, subdural hematoma ischemic stroke neoplasm * Guillain-Barre syndrome [anvita.info]

Etiologies include adh-producing neoplasms, injuries or diseases involving the hypothalamus, the pituitary gland, and the lung. This syndrome can also be drug-induced. [icd10data.com]

Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced. [fpnotebook.com]

Summary Epidemiology NSIAD is a very rare disease with 21 cases of hyponatremia due to NSIAD having been reported to date, the majority of them coming from 5 families. NSIAD affects mainly males. [orpha.net]

A prospective analysis of its epidemiology and the pathogenetic role of vasopressin Ann Int Med, 102 (1985), pp. 164-168 [4.] J.A. Clayton, I.R. LE Jeune, I.P. [elsevier.es]

[…] medical societies: American Academy of Pediatrics, American College of Epidemiology, American Pediatric Society, Endocrine Society, Florida Pediatric Society, Lawson-Wilkins Pediatric Endocrine Society, and Society for Pediatric Research Disclosure: [emedicine.medscape.com]

An elucidation of the pathophysiology of this syndrome will provide more insight into the action of AVP. An effective treatment of NSIAD is available. It consists of fluid restriction and administration of oral urea. [ncbi.nlm.nih.gov]

This Second Edition has been thoroughly updated with the latest information on pathophysiology, treatment, and drug dosing. New chapters cover obesity, vitamin D deficiency, autoimmune polyendocrine syndromes, and endocrine disorders in HIV/AIDS. [books.google.com]

2009 2009 Thirst perception and arginine vasopressin production in a kindred with an activating mutation of the type 2 vasopressin receptor: the pathophysiology of nephrogenic syndrome of inappropriate… Siddharth Gupta, Tim D. [semanticscholar.org]

Centers for Disease Control and Prevention advised. [medworm.com]

The ability to find a definitive cause in this case has provided validation to our patient, given a rational for preventative management with fluid restriction, and allows the potential for family screening. [endocrine-abstracts.org]

NSIAD must be early recognized and treated to prevent severe hyponatremia, which can show a dangerous impact on neonatal outcome. In fact, it potentially leads to death or, in case of survival, neurologic sequelae. [link.springer.com]

Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.it]