Two children died from sepsis within the first 12 months and one child died perinatally of cerebral palsy. [adc.bmj.com]

Sheu JN, Chen JH. 46,XY gonadal dysgenesis associated with congenital nephrotic syndrome and sepsis. Pediatr Nephrol 1999; 13: 927-9. 32. Drash A, Sherman F, Hartmann WH, Blizzard RM. [sjkdt.org]

Acute kidney injury may also be caused by excessive diuresis, interstitial nephritis due to use of diuretics or NSAIDs, sepsis or renal vein thrombosis [ 8 ]. [patient.info]

The most common infectious complications are bacterial sepsis, cellulitis, pneumonia, and peritonitis. [emedicine.medscape.com]

Differential Diagnosis of Acute Kidney Injury in Nephrotic Syndrome Acute allergic interstitial nephritis secondary to use of various drugs, including diuretics Acute tubular necrosis caused by volume depletion or sepsis Adverse effects of drug therapy [aafp.org]

Infants with congenital nephrotic syndrome may have failure to thrive and frequent infections. Although more commonly seen in individuals of Finnish descent, congenital nephrotic syndrome Finnish type has been reported worldwide. [malacards.org]

Patients with severe proteinuria may require bilateral nephrectomy because of severe hypoalbuminemia; dialysis should be initiated early to ameliorate nutritional deficits and mitigate failure to thrive. The disorder usually recurs in a renal graft. [msdmanuals.com]

The clinical course is marked by failure to thrive, recurrent life threatening bacterial infections, and early death from sepsis and/or uremia. A characteristic phenotype may be seen in children with CNS. [sjkdt.org]

Congenital Nephrotic Syndrome • Presents in first 3 months of life • Anasarca, hypoalbuminaemia, oliguria ‘Finnish’ Type Nephrotic Syndrome • Antenatally detectable : – Raised AFP in maternal serum and amniotic fluid • Complications – Failure o thrive [slideshare.net]

At this time, kidney transplantation seems to be the only treatment available for this condition. 0000093 Percent of people who have these symptoms is not available through HPO Abdominal distention Abdominal bloating Abdominal swelling Belly bloating [rarediseases.info.nih.gov]

However, others managed to survive life threatening infections including one patient who developed Haemophilus influenzae meningitis aged 14 months and another who recovered from pseudomonas septicaemia. [adc.bmj.com]

Common Features of the Disorder Increased risk for infections Increased levels of proteins in the blood Swelling of the body, particularly the face Malnutrition Growth delays Kidney failure Prognosis Individuals with Finnish Nephrosis have onset of symptoms [evolvegene.com]

About 10 to 30% develop progressive kidney failure. Relapses may respond to cyclophosphamide. [merckmanuals.com]

Acute kidney failure. Available online at . Accessed March 2014. MedlinePlus Medical Encyclopedia. Interstitial nephritis. Available online at . Accessed March 2014. MedlinePlus Medical Encyclopedia. Acute tubular necrosis. Available online at . [labtestsonline.it]

Since congenital nephrotic syndrome typically leads to kidney failure eventually, this radical approach merely pre-empts the inevitable. [gosh.nhs.uk]

However, others managed to survive life threatening infections including one patient who developed Haemophilus influenzae meningitis aged 14 months and another who recovered from pseudomonas septicaemia. [adc.bmj.com]

In the patient group, HLA-DR7 and HLA-CW6 were found to be significantly increased, while HLA-DQW1 and HLA-CW4 were significantly reduced. [cags.org.ae]

In the patient group, HLA-DR7 and HLA-CW6 were found to be significantly increased, while HLA-DQW1 and HLA-CW4 were significantly reduced. [cags.org.ae]