Presentation
Consequently, neurogenic shock's unique presentation includes: [5] [6] Neurogenic shock is diagnosed based on a person's symptoms and blood pressure levels. [en.wikipedia.org]
Therefore, awareness of and knowledge about the occurrence, clinical presentation and treatment are essential. [rba.elsevier.es]
Entire Body System
- Pain
[…] into two main categories: nociceptive pain and neuropathic pain. 2 Neuropathic pain, as outlined here, is defined as pain arising as a direct consequence of a lesion or disease affecting the somatosensory system. [ncbi.nlm.nih.gov]
Examining the time-to-improvement of pain in patients with chronic neuropathic pain due to spinal cord injury. J Pain. April 2013. 14(4, Supplement):S60. [medscape.com]
If you’ve recently injured your spine and are feeling nauseous or dizzy and have chest pain, you should call 911 and visit an emergency room immediately. [healthline.com]
These patients do not complain of dysuria or flank pain or increased urinary frequency. [6] Nevertheless, a standard test for UTI diagnosis in SCI patients is quoted from the National Institute on Disability and Rehabilitation Research (NIDRR). [jscisociety.com]
Neurologic
- Headache
Side effects were infrequent; only one patient complained of transient headaches. Neither hyponatremia nor serum electrolyte abnormalities occurred. [tandfonline.com]
On admission, in the emergency department, she presented with vomit, headache and somnolence (Glasgow Coma Scale (GCS) of 14) and her CT scan showed a triventricular hydrocephalus ( Fig. 1 ). [rba.elsevier.es]
Workup
Clinical Principle Urodynamics, cystoscopy and diagnostic renal and bladder ultrasound should not be used in the initial workup of the uncomplicated patient. [auanet.org]
Treatment
For treatment with lamotrigine, sleepiness is less likely, but caution should be exercised against skin eruption in the early phase of treatment. 5.5.2. [ncbi.nlm.nih.gov]
After assessment has been performed to exclude conditions requiring treatment and counseling, no treatment is an acceptable choice made by some patients and caregivers. [auanet.org]
Botulinum toxin type a is a safe and effective treatment for neurogenic urinary incontinence: results of a single treatment, randomized, placebo controlled 6-month study. J Urol 2005;174(1):196-200. Cruz F, Herschorn S, Aliotta P, et al. [renalandurologynews.com]
Pharmacological treatment Pharmacological treatment has no proven benefit, despite several drug treatments have already been reported. [neurologia.com]
“Botulinum toxin type a is a safe and effective treatment for neurogenic urinary incontinence: results of a single treatment, randomized, placebo controlled 6-month study.” J Urol 174(1): 196-200. Schurch, B., P. Denys, et al. (2007). [urotoday.com]
Prognosis
Cardiovascular prognosis of “masked hypertension” detected by blood pressure self-measurement in elderly treated hypertensive patients. JAMA. 2004 ; 291 : 1342–1349. [ahajournals.org]
[…] advocated in the treatment of NPE include fosfodiesterase inhibitors, beta1-antagonists alone or in combination with a vasodilator, and alfa-antagonists. 1,14 The pure form of NPE may resolve within 48–72 h with adequate treatment. 1,3,5 The patients prognosis [rba.elsevier.es]
Etiology
[…] years of various surgical technics directed toward alleviation of essential, or idiopathic, hypertension has renewed interest in the role of the sympathetic nervous system and its splanchnic divisions in regulation of blood pressure and their possible etiologic [jamanetwork.com]
[…] neurologic insult and the exclusion of other possible causes. 4 The most common causes of NPE are subarachnoid hemorrhages, followed by head trauma, seizures, embolic stroke, neurologic endovascular procedures and increased intracranial pressure (ICP) of any etiology [rba.elsevier.es]
Acquired stuttering can be further classified in psychogenic or neurogenic stuttering according to its etiology. [neurologia.com]
Intravesical oxybutynin has also been evaluated in limited studies involving detrusor overactivity of neurologic etiology [78]. Its use, however, requires catheterization and can be cumbersome. [urotoday.com]
Epidemiology
Epidemiology of traumatic spinal cord injury. Kirshblum S, Campagnolo DI, DeLisa JA, eds. Spinal Cord Medicine. Baltimore, Md: Lippincott Williams & Wilkins; 2002. 69-81. Go BK, DeVivo MJ, Richards JS. The epidemiology of spinal cord injury. [medscape.com]
To assemble new insights regarding the epidemiology, pathophysiology, diagnosis, evaluation and treatment of neurogenic stuttering. DEVELOPMENT. [neurologia.com]
Choo MS, Ku JH, Lee JB et al: Cross-cultural differences for adapting overactive bladder symptoms: results of an epidemiologic survey in Korea. World J Uro 2007; 25 : 505. 8. [auanet.org]
“Epidemiology and healthcare utilization of neurogenic bladder patients in a US claims database.” Neurourol Urodyn 30(3): 395-401. Metz, L. M., S. D. McGuinness, et al. (1998). “Urinary tract infections may trigger relapse in multiple sclerosis.” [urotoday.com]
Pathophysiology
Pathophysiology The underlying pathophysiologic mechanism is not yet fully understood. To this uncertainty contributes the fact that neurogenic stuttering can occur associated with multiple pathologies and multiple lesion sites. [neurologia.com]
Neurogenic shock results from damage to the spinal cord above the level of the 6th thoracic vertebra. [4] It is found in about half of people who suffer spinal cord injury within the first 24 hours, and usually doesn't go away for one to three weeks. [4] Pathophysiology [en.wikipedia.org]
Prevention
Treatment options are meant to stabilize you and prevent any additional injury or damage. First, your doctor will immobilize you to prevent further damage. Then they will give you fluids intravenously to regulate your blood pressure. [healthline.com]
If intubation and mechanical ventilation is needed, it should be performed using a technique which will avoid increase of either ICP or systemic arterial pressure yet maintain cerebral perfusion. 1 Ventilation with supplemental oxygen should prevent hypoxemia [rba.elsevier.es]
Urinary tract infections in patients with spinal cord lesions: Treatment and prevention. Drugs 2001;61: 1275-87. 5. García Leoni ME, Esclarín De Ruz A. Management of urinary tract infection in patients with spinal cord injuries. [jscisociety.com]
In the bladder, OnaBoNT-A acts at the presynaptic cholinergic junction where it prevents the release of acetylcholine from the presynaptic nerve terminal. This prevents stimulation of the detrusor muscle. [urotoday.com]
Population Age: Adults Gender: Male, Female Trial protocol: PT (Ongoing) CZ (Completed) Trial results: (No results available) EudraCT Number: 2013-003842-18 Sponsor Protocol Number: A301223 Start Date * : 2014-04-24 Sponsor Name: Erasmus MC Full Title: Prevention [clinicaltrialsregister.eu]