The patient was discharged on postoperative day 10 and during a 2-year follow-up has remained asymptomatic with normal bowel motility. The WCS score is 8 points, showing a significant difference compared to 20 points preoperatively. [ncbi.nlm.nih.gov]

There is also a report of two siblings with IND, mental retardation, dysmorphic features, hearing loss and short stature (13). Additional anomalies are more often observed in cases with diffuse IND (80%). [czytelniamedyczna.pl]

Due to excess abdominal tenderness and radiological findings, it was decided that an exploratory laparotomy would be appropriate. [ncbi.nlm.nih.gov]

In 30% of cases there may be IND-associated anomalies that include anorectal malformation, intestinal malrotation, megacystis, congenital short small bowel, hypertrophic pyloric stenosis, necrotizing enterocolitis, intestinal atresia, diffuse intestinal [czytelniamedyczna.pl]

She was admitted to hospital at 5 months because of a history of chronic constipation (she passed a hard stool with difficulty, every 4-5 days), loss of appetite, vomiting, and failure to thrive. She weighed 6700 g (10 th percentile). [czytelniamedyczna.pl]

Gálvez et al. [ 12 ] suggested that enteric nervous system dysplasia, including histological features of neuronal intestinal dysplasia, could be induced by chronic intestinal obstruction. [ncbi.nlm.nih.gov]

They also concluded that familial recurrence of associated IND-Malrotation-Short Bowel Syndrome suggests the possible presence of an autosomal recessive mode of inheritance. [czytelniamedyczna.pl]

Mitochondrial DNA analysis of an intestinal biopsy of patient 1 showed heteroplasmy consisting of a normal 16.5-kb band and an approximately 28-kb band, suggestive of a duplication. [journals.sagepub.com]

Neonatal onset of symptoms with ileus, meconium plug syndrome or neonatal constipation occurs in those with a coincidence of IND and aganglio-nosis (21). There is no significant difference in sex distribution. [czytelniamedyczna.pl]

This difficulty in exact estimation of the frequency of IND results from the considerable confusion regarding the essential diagnostic criteria. [czytelniamedyczna.pl]