Nitrobenzene poisoning presenting as Methemoglobinemia. Muller J Med Sci Res 2014;5:185-7 How to cite this URL: Bharadiya AA, Lakhotia AN, Patange A, Jaju JB, Choraria K. Nitrobenzene poisoning presenting as Methemoglobinemia. [mjmsr.net]

Pulse oximeters available at present are not useful in patients treated with methylene blue and should be used cautiously in the presence of cyanosis of unknown aetiology. [ncbi.nlm.nih.gov]

Late presentation of secondary cycling - nitrobenzene poisoning: A rare case report. IAIM, 2014; 1(3): 39-43. Transcript Late presentation of secondary cycling International Archives of Integrated Medicine, Vol. [documents.tips]

Late presentation of secondary cycling - nitrobenzene poisoning ISSN: 2394-0026 (P)Case Report ISSN: 2394-0034 (O) Late presentation of secondary cycling -nitrobenzene poisoning: A rare case report Virendra Goyal* 142,Taruchaya Nagar, Tonk Road, Jaipur [pubhtml5.com]

• Lymphadenopathy

  There was no pallor, icterus, cyanosis, lymphadenopathy, head lag, respiratory distress, pungent odor of the organophosphorus compounds, flaps, or altered mental status. [mjmsr.net]

• Nausea

  Symptoms of acute poisoning include headache, drowsiness, nausea, ataxia, cyanosis, and, in extreme cases, respiratory failure. Chronic exposure to nitrobenzene may cause headache, fatigue, loss of appetite, and anemia. [medical-dictionary.thefreedictionary.com]

  The symptoms and signs of poisoning are nausea, vomiting, prostration, intense gray blue cyanosis, convulsions, and coma (Sollmann). As with other benzene derivatives, there is a direct toxic effect FULL TEXT [annals.org]

  Patient complained of epigastric discomfort and nausea. She did not have any vomiting, loss of consciousness, or seizures while being transferred to the hospital. [mjmsr.net]

  In normal individuals methaemoglobin level must be greater than 10% to be clinically recognized and only mild symptoms, headache, fatigue and nausea occur at level of 20-30% [4]. [jpgmonline.com]

• Headache

  Symptoms of acute poisoning include headache, drowsiness, nausea, ataxia, cyanosis, and, in extreme cases, respiratory failure. Chronic exposure to nitrobenzene may cause headache, fatigue, loss of appetite, and anemia. [medical-dictionary.thefreedictionary.com]

  These cases have been characterized by marked cyanosis, sometimes accompanied by vertigo and weakness, digestive disorders, headache and somnolence. [jamanetwork.com]

  Eighteen hours after admission he was fully conscious but started having headache and occasional vomiting. Eight hours later, he became pale, sick, drowsy and had a seizure. [indianpediatrics.net]

  She was then taken to a local hospital where she presented with recurrent vomiting, headache, and light-headedness. She had a gastric lavage done and started on supportive treatment with intravenous fluids and intravenous paracetamol. [ijabmr.org]

  Beyond 20%, headache, dyspnea, chest pain, tachypnea, and tachycardia develop. [amhsjournal.org]

Methemglobinemia: Differential diagnoses and workup, e medicine from web med Available from: http://www.emedicine.medscape.com/article/956528-diagnosis [cited in 2010] Cited Here 8. Verive M, Kumar M. [journals.lww.com]

Methemglobinemia: Differential diagnoses and workup, e medicine from web med. Available http://www.emedicine.medscape.-diagnosis. Accessed Curry S. Methaemoglobinemia. Ann 1982; 11: 214-221. Whitwan JG, Taylor AR, White JM. [documents.tips]

(See Workup.) The most important aspects of the management of methemoglobinemia are recognition of the condition and prompt initiation of treatment, when indicated. [emedicine.medscape.com]

A case of methemoglobinemia Methemglobinemia: Differentialcaused by hair dyeing with henna. diagnoses and workup, e medicine fromKorean J Med, 2007; 72(2): 314–317. web med. Available14. [pubhtml5.com]

Important factors in treatment are discussed. These include, gastric lavage, the administration of methylene blue and exchange transfusion. The possibility of a late haemolytic reaction being a complication of methylene blue treatment is mentioned. [unboundmedicine.com]

Plan of management is based upon the principles of decontamination along with symptomatic and supportive treatment. lue is the drug of choice (antidote) for the treatment of acquired (toxic) ]. [documents.tips]

Methylene blue and exchange transfusion were the therapeutic methods applied in the treatment of the methemoglobinemia. Forty-eight hours after ingestion, a blood sample was collected in ICU and sent to our laboratory. [ncbi.nlm.nih.gov]

Treatment of aniline poisoning with exchange transfusion. J Toxicol Clin Toxicol 1988;26:357-64. 17. Harvey JW, Keitt AS. Studies of the efficacy and potential hazards of methylene blue therapy in aniline-induced methaemoglobinaemia. [galaxyjeevandhara.com]

Methemogobinemia can leads to safety (IPCS) – 2003 (8.11)high mortality but effective treatment with Nitrobenzene. Environmental healthmethylene blue is preferential. criteria 230. Geneva: WHO. [pubhtml5.com]

Younger age indicated a better prognosis. The absence of oculovestibular, oculocephalic reflexes, pupillary reflexes and / corneal reflexes suggests, poor outcome. The patient with low coma score of 3 to 4 had poorer prognosis. [japi.org]

Please find relevant information on First Aid for Fountain Pen Ink Poisoning regarding cause, signs & symptoms, administration of first aid treatment, prognosis, preventive measures, and additional resources HERE. [dovemed.com]

Prognosis The prognosis of mild cases of methemoglobinemia is very favorable. In severe cases, the prognosis is determined by the degree of anoxic end-organ damage. [emedicine.medscape.com]

Methemoglobinemia: Etiology, pharmacology, and clinical management. Ann Emerg Med 1999;34:646-56. 12. Ajmani A, Prakash SK, Jain SK, Shah P. Acquired methaemoglobinaemia following nitrobenzene poisoning. J Assoc Physicians India 1986;34:891-2. 13. [galaxyjeevandhara.com]

Conclusion: The most common cause of fever with acute onset altered sensorium, is an infective etiology, however noninfectious causes remain an important, but uncommon cause and proper diagnosis is sometimes missed in cases with accompanying complaints [japi.org]

Methemoglobinemia: etiology, pharmacology, and clinical management. Ann Emerg Med 1999;34:646-56. 4. Coleman MD, Coleman NA. Drug-induced methemoglobinemia. Treatment issues. Drug Saf 1996;14:394-405. 5. [ijccm.org]

Methemoglobinemia: Etiology, pharmacology, and clinical management. Ann Emerg Med 1999;34:646-56. [ PUBMED ] 2. Gupta A, Jain N, Agrawal A, Khanna A, Gutch M. A fatal case of severe methaemoglobinemia due to nitrobenzene poisoning. [ijabmr.org]

Methemoglobinemia: Etiology, Pharmacology, and clinical management. Ann Emerg Med 1999;34:646-56. [ PUBMED ] 3. Hoffman RS, Nelson SL, Howland MA, Lewin NA, Flomenbaum NE, Goldfrank LR, editors. Goldfrank's Manual of toxicological emergencies. [joacp.org]

Abstract Clinical and epidemiological information was collected on 1033 cases of poisoning which occurred during a period of 18 months. [pediatrics.aappublications.org]

These events are inadequately characterised and their quantification has been difficult due to limitations imposed by lack of clarity about its epidemiology and pathophysiology and also due to lack of any standardized te sting methods. [japi.org]

Indigo carmine Resorcinol Metoclopramide [50] Antibiotics – Sulfonamides, nitrofurans, and para-aminosalicylic acid Industrial/household agents – Aniline dyes, nitrobenzene, naphthalene (moth balls), aminophenol, and nitroethane (nail polish remover) Epidemiology [emedicine.medscape.com]

Additional pathophysiology content helps you better understand the effects of diseases and injuries on the body’s normal physiologic processes. [books.google.com]

Chemical burns: Pathophysiology and treatment. Burns. 2010;36(3):295–304. Web of Science Crossref Google Scholar [13] Cortazzo JA, Lichtman AD. Methemoglobinemia: A Review and recommendations for management. J Cardiothorac Vasc Anesth. [degruyter.com]

Physicians must be aware of common substance containing nitrobenzene compound, pathophysiology of these compound, and its complications and treatment modalities. References 1. International Programme on Chemical Safety (IPCS). Nitrobenzene. [amhsjournal.org]

Pathophysiology RBCs contain hemoglobin, which has a quaternary structure. Each hemoglobin molecule is composed of 4 polypeptide chains. [emedicine.medscape.com]

These events are inadequately characterised and their quantification has been difficult due to limitations imposed by lack of clarity about its epidemiology and pathophysiology and also due to lack of any standardized te sting methods. [japi.org]

It is also important to take care of the secondary cycling of nitrobenzene from body stores to prevent secondary recurrence of symptoms in patients after heavy exposure. [ncbi.nlm.nih.gov]

(ERG, 2020) Protective Clothing Excerpt from NIOSH Pocket Guide for Nitrobenzene: Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact. [cameochemicals.noaa.gov]

Immediate identification based on clinical features, odour of the compound with supporting evidence of increased methaemoglobin levels will help in a timely intervention thus preventing fatal outcome. [ijmrhs.com]

The importance of early identification of the compound on the basis of clinical suspicion corroborative with methemoglobin levels with timely intervention is required to prevent fatal outcome (Agrawal et al., 2011). [journalcra.com]