Before necrosis the following are common presentations :
- Poor oral hygiene
- Excessive salivation
- Malodour from the mouth
- Grey discoloration
- Gingival ulcer formation
These are followed by rapid, painless and extensive necrosis of the oral cavity which should involve the cheek, nose and palate bones. There may be necrosis of the genitalia and mucocutaneous gangrene may be seen during the neonatal period.
Entire Body System
Noma (cancrum oris, gangrenous stomatitis) is a severe gangrenous disease of orofacial tissues seen in malnourished children. [symptoma.com]
The many historical synonyms for this disease together with other historical data indicate that orofacial gangrene in children was a common affection in Europe in previous centuries. [ncbi.nlm.nih.gov]
The child had experienced occasional cough and fever and also had erupting tooth buds. These tooth buds had been seen as the cause of the cough and fever by the traditional herbalist; hence, they were extracted. [ncbi.nlm.nih.gov]
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The patient continued to have a non-healing oral ulcer with progressive pallor and was finally diagnosed as having acute lymphoblastic leukaemia. Immunodeficiency was ruled out by appropriate investigations. [ncbi.nlm.nih.gov]
It involves the extraction of tooth buds in babies with common childhood illnesses such as fever, cough, and diarrhea. It is thought that the tooth buds are responsible for the ailments seen in these infants. [ncbi.nlm.nih.gov]
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Noma is usually preceded by a debilitating illness, such as measles, malaria, diarrhea, tuberculosis, or necrotizing ulcerative gingivitis. [nejm.org]
KEYWORDS: Cancrum oris; Developing countries; Human rights; Malnutrition; Neglected diseases; Noma [ncbi.nlm.nih.gov]
Sort By: Most Relevant Most Recent Noma The neglected disease that destroys faces and lives Noma, a neglected and little-known non-contagious disease, mostly affects children under five living in poverty. [msf.org]
Noma should be formally acknowledged as a WHO neglected disease. States should promote a resolution at the World Health Assembly to list Noma as a neglected disease. [righttofood.org]
The clinical course for each case varies a great deal and the mortality and morbidity rate is high as 70-90% of cases die . It remains to be seen if this high mortality is as a result of clinical manifestations or as a result of poor or inaccurate diagnosis.
Fusobacterium necrophorum and Prevotella intermedia are believed to play a role in the development of this disease . The interactions that bring about the disease remain unclear but it is believed to develop following acute necrotising fasciitis.
The following are risk factors documented for the condition :
The condition is a disease of children as 80% of cases are seen in patients less than 10 years old . It is common in developing countries, most especially in the poorest areas of Africa, parts of Asia and parts of South America. A total of 100,000 people are affected per year by this condition.
Noma refers to a severe disfiguring gangrene of the face and mouth which first starts as gingival ulcer before it spreads rapidly through the tissues in the mouth and face . Unlike what is obtainable with other facially infectious processes, noma can disrupt anatomic barriers by spreading through the bone and muscle instead of progressing along anatomic spaces of the head and neck. The gangrene that results may involve the maxilla and the mandible and also extend to the infra-orbital margins as well as the nose.
The main preventive measures include proper nutrition, cleanliness as well as sanitation .
Noma is a type of disease which destroys the mucous membranes of the mouth as well as other tissues. It is seen mostly in malnourished children in parts of the world known for uncleanliness and living closely with animals.
The main cause is unknown however it I believed to be as a result of bacteria known as fusospirochetal organisms. The disorder is most potent when the child has had illnesses such as measles, scarlett fever, tuberculosis, cancer and other forms of immunocompression.
Treatment is often with the aid of antibiotics but the chance of survival is often very poor most of the time.
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