Abstract This article reviews the various aspects of non-immune hydrops fetalis, including the historical background, aetiology, clinical presentation, antenatal diagnosis and perinatal management, as well as presenting some data on cases of non-immune [ncbi.nlm.nih.gov]

• Fever of Unknown Origin

  We conclude, that listeriosis should be excluded, whenever a non-immune hydrops fetalis is associated with septicemia, influenza-like illness and fever of unknown origin. [ncbi.nlm.nih.gov]

• Collapse

  […] forms of hydrops that are expressed with a clinical trend towards a worse prognosis, characterized by the intrauterine death of the fetus or the birth of a hydropic fetus that does not survive because of respiratory insufficiency and cardiocirculatory collapse [ncbi.nlm.nih.gov]

• Single Transverse Palmar Crease

  At birth, both individuals were noted to have marked edema of the entire body, slightly low set ears, small nose, mild micrognathia, small chest, camptodactyly, single transverse palmar creases, rhizomelic shortening of the upper extremities, slight ankle [ncbi.nlm.nih.gov]

• Broad Nasal Bridge

  nasal bridge, lymphedema, tooth anomalies, and ear defects). [ncbi.nlm.nih.gov]

[…] genetic physician or genetic counselor who will be evaluating your family health history for possible inheritable conditions that would cause hydrops Any other specialists as necessary to address underlying issues or abnormalities uncovered by the overall workup [chw.org]

Extensive clinical workup is required to attempt to identify the specific etiology. In patients in whom NIHF is suspected, the search for a cause starts with a maternal evaluation. [slideshare.net]

• Liver Biopsy

  In ascites fluid foamy macrophages were found, in a liver biopsy cytoplasmic inclusions and membrane-bound vacuoles were seen. [ncbi.nlm.nih.gov]

The survival rate in the intrauterine treatment group was higher than in the nontreatment group (treatment group: 10/15; non-treatment group: 5/34, p 0.001). [ncbi.nlm.nih.gov]

Treatment (for a newborn): Treatment may involve direct transfuions of packed red blood cells, small needle aspiration to remove any excess fluid from around the lung or abdomen. [lymphedemapeople.com]

Treatment Your doctors will try to identify the underlying cause of fetal hydrops. Certain conditions can be treated prenatally. [women.texaschildrens.org]

AIM: The prognosis for non-immune hydrops fetalis (NIHF) is still poor despite progress in perinatal care. [ncbi.nlm.nih.gov]

Prognosis and Outcomes: The prognosis depends on etiology, response to therapy if treatable, and on the gestational age at detection and delivery. [smfm.org]

Knowledge of the primary etiology is important for counseling and therapy. 2015 Japan Society of Obstetrics and Gynecology. [ncbi.nlm.nih.gov]

First, we performed epidemiological studies to determine the critical period during which maternal infection led to hydrops fetalis. [jstage.jst.go.jp]

Summary Epidemiology The prevalence of NIHF is unknown as it is difficult to obtain when many cases are not diagnosed before intrauterine death or may spontaneously resolve antenatally. Currently, NIHF constitutes up to 90% of all HF cases. [orpha.net]

[Source] Pediatric Hydrops Fetalis: Background, Pathophysiology, Epidemiology. 2016 Mar 24 [cited 2016 Apr 29]. [Source] Hydrops fetalis. In: Wikipedia, the free encyclopedia [Internet]. 2016 [cited 2016 Apr 29]. [keralamedicaljournal.com]

Diagnosis/definition: Non-immune hydrops is the presence of two or more abnormal fetal fluid collections in the absence of red cell alloimmunization. ( Figure 1 ).Epidemiology/Incidence: Non-immune hydrops fetalis (NIHF) refers specifically to cases of [smfm.org]

Congenital chylothorax: a prospective nationwide epidemiological study in Germany. Archives Dis Child Fetal & Neonatal Ed. 2015;100(2):F169-72. [adhb.govt.nz]

The exact pathophysiology is still poorly understood. It is important to detect NIHF early, diagnose the underlying cause and institute appropriate treatment. There is need for autopsy of all fetuses or neonates who die from NIHF. [ncbi.nlm.nih.gov]

Non-immune hydrops fetalis: a short review of etiology and pathophysiology. Am J Med Genet A. 2012;158A:597–605. CrossRef PubMed Google Scholar 2. Randenberg AL. Nonimmune hydrops fetalis part I: etiology and pathophysiology. [link.springer.com]

General Pathophysiology Fluid accumulates within … View Full Text Log in using your username and password Log in through your institution You may be able to gain access using your login credentials for your institution. [neoreviews.aappublications.org]

Evidence of endothelium involvement in the pathophysiology of hydrops fetalis? Early Hum Dev 2000;57:205-9. Crossref [hkmj.org]

[Source] Pediatric Hydrops Fetalis: Background, Pathophysiology, Epidemiology. 2016 Mar 24 [cited 2016 Apr 29]. [Source] Hydrops fetalis. In: Wikipedia, the free encyclopedia [Internet]. 2016 [cited 2016 Apr 29]. [keralamedicaljournal.com]

We suggest that an effective thalassemia-screening program for prevention and control of homozygous alpha-thalassemia-1 be established in all areas where the alpha-thalassemia-1 gene is prevalent. Copyright (c) 2005 S. Karger AG, Basel. [ncbi.nlm.nih.gov]

Fetal anemia and hydrops due to intrauterine fetal blood transfusion can be prevented. [tibbiyardim.com]

In such type of cases, it is required to counsel the couple that HF could not be preventable and hydrops baby usually cannot continue life except some correctable conditions e.g., congenital heart disease and some cases of diaphragmatic hernia. [jemds.com]

So, it is hard for this mother for optimum management and prevention of hydrops fetalis in subsequent pregnancies. [jmedsoc.org]