Edit concept Question Editor Create issue ticket

Non-Seminoma Testicular Cancer

Non Seminoma Testicular Cancer


Presentation

  • The present study aims to determine if socioeconomic factors may play a role in both etiology and survival from non-seminoma testicular cancer.[ncbi.nlm.nih.gov]
  • This survey demonstrates the importance of having all treatment information presented in an objective fashion and for the need to seek the opinion of more than one physician, preferably in a different subspecialty.[texasoncology.com]
  • Let’s take a quick look at the clinical presentation, pathologic subtypes, and prognosis of this common cancer. Clinical Presentation Testicular cancer usually presents as a firm, painless enlargement of the testis.[pathologystudent.com]
  • Some men may also present initially with symptoms such as a neck mass, bone pain, cough or shortness of breath if the cancer has already spread to other organs. However, the condition normally presents in its early stages.[myvmc.com]
  • Presented February 16, 2017. Expert Point of View: Prof. Noel Clarke, MBBS, FRCS, ChM Noel Clarke, MBBS, FRCS, ChM Formal discussant of the 111 trial, Prof.[ascopost.com]
Pathologist
  • The pathologists look at it carefully under the microscope and tell doctors if it is a seminoma, non-seminoma or some mixture of both. This helps doctors decide how to advise men on what to do next.[sharecare.com]
  • Germinal cell tumors Due to the frequent appearance of several tumor type components in germinal tumors of the testis, the pathologist must study several microscopic sections.[oncolex.org]
Surgical Procedure
  • Orchidectomy An orchidectomy is a surgical procedure to remove a testicle. If you have testicular cancer, the whole of the affected testicle will need to be removed because only removing the tumour may lead to the cancer spreading.[nhs.uk]
Tingling
  • … news.cancerconnect.com Like Like Comment Neuropathy (Numbness and Tingling )- How is it Prevented and Treated? Like Like Comment Looking for women living with breast cancer for research study.[news.cancerconnect.com]
  • Men in the study group who smoked regularly were more likely to have symptoms of Raynaud's, numbness or tingling in the hands or feet, and hearing impairment than the men in the study who had never smoked.[raysahelian.com]
  • […] hair loss nausea sore mouth and mouth ulcers loss of appetite fatigue breathlessness and lung damage infertility ringing in your ears ( tinnitus ) skin that bleeds or bruises easily low blood counts increased vulnerability to infection numbness and tingling[nhs.uk]
Sleep Disturbance
  • Cancer Connect 4 days Cancer Survivorship: Insomnia and Sleep Disturbance Dr. Barrie Cassileth Chief of Integrative Medicine MSKCC. Mind body therapy, medication, exercise, CAM all play a role.[news.cancerconnect.com]
Insomnia
  • Cancer Connect 4 days Cancer Survivorship: Insomnia and Sleep Disturbance Dr. Barrie Cassileth Chief of Integrative Medicine MSKCC. Mind body therapy, medication, exercise, CAM all play a role.[news.cancerconnect.com]
Testicular Mass
  • Tabs Content Clinical Overview Diagnosis Indications for Testing Testicular mass Testicular pain Nonresolving epididymitis/orchitis Laboratory Testing AFP, beta-hCG, and LDH serum concentrations – mandatory prior to testicular cancer treatment Molecular[arupconsult.com]
  • Testicular Masses. American Family Physician [serial online] 1998 [cited: February 15, 1998]; 57(4). Available from URL: Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL. Harrisonà ₠℠s Principles of Internal Medicine.[myvmc.com]
Testicular Pain
  • Tabs Content Clinical Overview Diagnosis Indications for Testing Testicular mass Testicular pain Nonresolving epididymitis/orchitis Laboratory Testing AFP, beta-hCG, and LDH serum concentrations – mandatory prior to testicular cancer treatment Molecular[arupconsult.com]
  • Testicular pain is reported in up to one fifth of cases.[en.wikipedia.org]
Swelling of the Scrotum
  • Consult a doctor if you have any of these symptoms: Swelling in the scrotum A lump or swelling in either testicle Build-up of fluid on the scrotum Dull ache in the groin or lower abdomen Pain or discomfort in the scrotum or a testicle Cleveland Clinic[my.clevelandclinic.org]
Scrotal Pain
  • References: [8] [9] [3] [10] [11] [11] [12] [13] [14] Clinical features Painless testicular nodule or swelling Negative transillumination test Dull lower abdominal or scrotal discomfort is more common than acute scrotal pain (30–40% of cases).[amboss.com]

Workup

  • Testicular Cancer Workup. Available online at . Accessed July 2014. Motzer RJ, Agarwal N, Beard C, et al. Testicular Cancer. Journal of the National Comprehensive Cancer Care Network . 2009;7:672-693. Available online at . Accessed July 2014.[labtestsonline.it]

Treatment

  • The potential benefits of receiving cancer treatment must be carefully balanced with the potential risks of receiving cancer treatment. The following is a general overview of the treatment of stage I testicular non-seminoma.[texasoncology.com]
  • Treatment protocols for nonseminoma testicular cancer are provided below, including the following: Recommendations for treatment of stage I-III disease Second-line recommendations for metastatic disease Recommendations for persistent or recurrent disease[emedicine.medscape.com]
  • But seminomas and nonseminomas have two different categories of treatments and that's why we distinguish the two categories.[howcast.com]
  • How We Can Stop Them in Their Tracks Recent statistics reveal some fantastic news: fewer Americans than ever before are being diagnosed with or dying from ca Cancer Connect 2 days Heartburn - GERD - Reflux and Cancer Treatment Cancer and its treatment[news.cancerconnect.com]
  • Kataja This Clinical Practice Guideline for Testicular Seminoma and Non-seminoma features epidemiology of these rare malignancies in young men, the diagnosis, management of the primary tumour, post-orchiectomy staging and risk assessment, treatment recommendations[esmo.org]

Prognosis

  • Featured 6,735 Community 48 Act Your Age When It Comes to Skin Care Act Your Age When It Comes to Skin Care Cancer Connect 12 hrs Cyramza Improves Survival in Poor-Prognosis Liver Cancer Cyramza Improves Survival in Poor-Prognosis Liver Cancer Cancer[news.cancerconnect.com]
  • : Unfavorable prognosis [1] is defined by incomplete response, high marker levels, high tumor volume, an extratesticular primary tumor, and late relapse Treat these patients with chemotherapy; clinical trials or conventional-dose VeIP or TIP regimens[emedicine.medscape.com]
  • ., Artificial neural networks for diagnosis and prognosis in prostate cancer, Semin. Urol.[link.springer.com]
  • If you have testicular cancer, you may have questions about your prognosis. A prognosis is the doctor’s best estimate of how cancer will affect someone and how it will respond to treatment. Prognosis and survival depend on many factors.[cancer.ca]

Etiology

  • The present study aims to determine if socioeconomic factors may play a role in both etiology and survival from non-seminoma testicular cancer.[ncbi.nlm.nih.gov]
  • Etiology Risk factors Cryptorchidism (increased risk for germ cell tumors ) [4] Contralateral testicular cancer Germ cell neoplasia in situ (GCNIS) Family history of testicular cancer Klinefelter syndrome, Down syndrome (increased risk for germ cell tumors[amboss.com]

Epidemiology

  • Kataja This Clinical Practice Guideline for Testicular Seminoma and Non-seminoma features epidemiology of these rare malignancies in young men, the diagnosis, management of the primary tumour, post-orchiectomy staging and risk assessment, treatment recommendations[esmo.org]
  • […] common in Hispanics compared to Asian and black populations in the US References: [1] [2] [3] Epidemiological data refers to the US, unless otherwise specified.[amboss.com]
  • Monitoring AFP, LDH, beta-hCG – markers of choice; refer to National Comprehensive Cancer Network (NCCN) Testicular Cancer guidelines (2016) for suggested monitoring schedule Schedule varies based on tumor stage/type and treatment Background Epidemiology[arupconsult.com]
  • These groups are defined by epidemiological characteristics, histological composition and chromosomal constitution (Table 1).[atlasgeneticsoncology.org]
Sex distribution
Age distribution

Pathophysiology

  • […] in African Americans Highest incidence in Caucasians Risk Factors Personal history of testicular cancer Family history of testicular cancer – highest risk if sibling had testicular cancer Cryptorchidism Infertility /subfertility Klinefelter syndrome Pathophysiology[arupconsult.com]
  • Epidemiology : usually develop after the age of 4 Pathophysiology : produces amounts of testosterone and a small amount of estrogen, progesterone, and corticosteroids testosterone excess causes precocious puberty in males (and masculinization in females[amboss.com]

Prevention

  • Cancer Connect 3 days Overview of Melanoma Melanoma: Signs & Symptoms, Diagnosis, Screening, Prevention & Early Detection Cancer Connect 3 days Sunscreen May Reduce Risk of Melanoma Regular use of sunscreen may help prevent melanoma.[news.cancerconnect.com]
  • Prevention It’s not possible to prevent testicular cancer since most of the risk factors (young age, undescended testicles, being white, etc.) cannot be changed or controlled.[urmc.rochester.edu]
  • As such, it’s not possible to prevent testicular cancer in most cases. For this reason, early detection is key.[gopedal.org]
  • Preventing testicular cancer There are no proven measures to prevent testicular cancer. Source Understanding Testicular Cancer, Cancer Council Australia ? 2018. Last medical review of source booklet: August 2018.[cancer.org.au]
  • Prevention Performing a testicular self-examination (TSE) each month may help detect testicular cancer at an early stage, before it spreads. Finding testicular cancer early is important for successful treatment and survival.[stlukes-stl.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!