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Non-viral Hepatic Infection

Hepatic Infections (excl Viral)


Presentation

  • Improve your interpretation of presenting symptoms with 41 new topics and 7 new references in the Differential Diagnosis section.[books.google.com]
  • Improve your interpretation of presenting symptoms with 41 new topics and 7 new references in the Differential Diagnosis section. Access current diagnostic and therapeutic information on more than 700 common medical conditions.[books.google.com]
  • Patients often present with fever, abdominal pain, and jaundice. Multiple serum lab values are often elevated, including AST, ALT, and GGT.[radiopaedia.org]
  • Invited lecture. www.bhiva.org/documents/Conferences/2016Manchester/Presentations/160419/PatrickKennedy.pdf (PDF slides) www.bhiva.org/160419PatrickKennedy.aspx (webcast)[thebodypro.com]
  • This review encompasses the major infections of the liver and biliary tree other than viral hepatitis and includes aspects of pathogenicity, epidemiology, clinical presentation, diagnosis and management.[ncbi.nlm.nih.gov]
Physician
  • Whether treatment will be successful depends on many factors, and these are best discussed with a physician who specializes in liver diseases. When treatment is successful, liver scarring and the potential for liver cancer are reduced.[sfcdcp.org]
  • Based on a text by Professor Court Pedersen, consultant, Professor Ove Schaffalitzky de Muckadell, consultant Last updated 09.11.2010 Reader and honorary consultant physician in infectious diseases and general medicine[netdoctor.co.uk]
  • Treatment options need to be discussed with a knowledgeable physician, as the appropriate combination is dependent upon multiple factors.[onhealth.com]
  • Viral hepatitis guide for practicing physicians. Cleve Clin J Med 2000; 67(suppl 1):SI6–SI45. Koff RS. Clinical manifestations and diagnosis of hepatitis A virus infection. Vaccine 1992; 10(suppl 1):S15–S17. Winokur PL, Stapleton JT.[clevelandclinicmeded.com]
  • Clinical criteria for inclusion in the study were a physician's diagnosis of acute viral hepatitis that was based on the discrete onset of signs and symptoms, serum aminotransferase activity that was more than 2.5 times the upper limit of normal, and[nejm.org]
Lymphadenopathy
  • […] the hepatic hilum (periportal edema) possible diffusely decreased parenchymal attenuation on noncontrast CT diffuse edematous change hepatic steatosis may be a cause (steatohepatitis) or a result of acute hepatitis possible periportal/hepatoduodenal lymphadenopathy[radiopaedia.org]
  • Mild hepatomegaly, splenomegaly, and cervical lymphadenopathy are found in 85%, 15%, and 14% of infected patients, respectively.[clevelandclinicmeded.com]
Epilepsy
  • This streamlined new edition covers the latest on genetics, neurology, infectious disease, melamine poisoning, sexual identity and adolescent homosexuality, psychosis associated with epilepsy, and more.[books.google.com]
Tachycardia
  • Ferri s popular "5 books in 1" format provides quick guidance on vitamin-D deficiency, statin-induced muscle syndrome, postural tachycardia syndrome (POTS), and much more.[books.google.com]
  • Ferri's popular "5 books in 1" format provides quick guidance on vitamin-D deficiency, statin-induced muscle syndrome, postural tachycardia syndrome (POTS), and much more.[books.google.com]

Workup

Coxiella Burnetii
  • burnetii (Q-fever) Rickettsia rickettsii (Rocky Mountain spotted fever) Treponema pallidum (secondary syphilis) Rickettsia typhi (typhus fever) Granulomatous disease Mycobacterium tuberculosis Sarcoidosis Hereditary disease/disorder Wilson disease Hemochromatosis[arupconsult.com]
Rickettsia Rickettsii
  • rickettsii (Rocky Mountain spotted fever) Treponema pallidum (secondary syphilis) Rickettsia typhi (typhus fever) Granulomatous disease Mycobacterium tuberculosis Sarcoidosis Hereditary disease/disorder Wilson disease Hemochromatosis Alpha-1-antitrypsin[arupconsult.com]

Treatment

  • Treatment for hepatitis Treatment depends on the type of hepatitis. Talk to your doctor about the treatment that is recommended for you.[betterhealth.vic.gov.au]
  • For some individuals, the risks of treatment may not be justified. Chronic Hepatitis C Treatment Treatment of chronic hepatitis C has evolved, rendering many earlier drugs obsolete.[onhealth.com]
  • Viekira Pak from AbbVie, a combination HCV treatment, was approved in December 2014. Viekira Pak is used for treatment of genotype 1a and 1b HCV in patients with or without cirrhosis.[drugs.com]
  • Treatment Hepatitis C is treated with anti-viral medications with the objective of having no hepatitis C virus detected in the body after completion of a 12-week course of treatment.[southerncross.co.nz]

Prognosis

  • A need for prompt investigation is emphasised by the potentially rapid progression and poor prognosis of some bacterial and fungal infections, and the public health implications of parasitic diseases.[ncbi.nlm.nih.gov]
  • Treatment and prognosis Treatment depends on the etiology of the acute hepatitis.[radiopaedia.org]
  • Natural history and prognosis of hepatitis B. Semin Liver Dis. 2003;23(1):47–58. Locarnini S, Hatzakis A, Chen D-S, Lok A. Strategies to control hepatitis B: Public policy, epidemiology, vaccine and drugs. J Hepatol. 2015;62(1):S76–86.[revistagastrocol.com]
  • Acute Hepatitis B Infection, 4.1 What happens when Initially infected. 4.2 Symptoms. 4.3 Treatment 4.4 Prognosis 5. Chronic Hepatitis B infection. 5.1 How does chronic Hepatitis B Develop. 5.2 Symptoms 5.3 Treatment 5.4 Prognosis 6.[hon.ch]

Etiology

  • In some cases, no clear etiology could be found (cryptogenic cirrhosis). However, the incidence of HCC varies greatly with etiologies and the molecular mechanisms linking cirrhosis and HCC are not well defined.[eurekaselect.com]
  • Etiologies may include: viral hepatitides: (e.g.[radiopaedia.org]
  • However, this study did not implicate HGV as an etiologic agent of non-A–E hepatitis.[nejm.org]
  • Definition and Etiology Hepatitis A virus (HAV) is a cause of acute liver inflammation or hepatitis. It can cause relapsing signs and symptoms but not a chronic infection. The virus is a 27-nm-diameter nonenveloped RNA virus.[clevelandclinicmeded.com]

Epidemiology

  • Related Journals: American Journal of Epidemiology, Journal of Clinical Epidemiology, Cancer Epidemiology Biomarkers and Prevention, International Journal of Epidemiology, Epidemiology, Journal of Immunology, Annual Review of Immunology, Journal of Allergy[hepatitis.imedpub.com]
  • This review encompasses the major infections of the liver and biliary tree other than viral hepatitis and includes aspects of pathogenicity, epidemiology, clinical presentation, diagnosis and management.[ncbi.nlm.nih.gov]
  • The diverse patterns of hepatitis A epidemiology in the United States: implications for vaccination strategies. J Infect Dis 1998; 178:1579–1594. Weekly epidemiological record.[clevelandclinicmeded.com]
  • Strategies to control hepatitis B: Public policy, epidemiology, vaccine and drugs. J Hepatol. 2015;62(1):S76–86. Ganem D, Prince AM. Hepatitis B virus infection-natu- ral history and clinical consequences. N Engl J Med. 2004;350(11):1118–29.[revistagastrocol.com]
  • Rickettsia typhi (typhus fever) Granulomatous disease Mycobacterium tuberculosis Sarcoidosis Hereditary disease/disorder Wilson disease Hemochromatosis Alpha-1-antitrypsin deficiency Ischemia Parasitic infection Liver trematodes Toxocara spp Background Epidemiology[arupconsult.com]
Sex distribution
Age distribution

Pathophysiology

  • […] source is found in 42% of all cases. 4 In the United States, a region of relatively low hepatitis A endemicity, calculations based on surveillance data from 1989 indicated annual medical and work-loss costs of approximately US 200 million. 5 Back to Top Pathophysiology[clevelandclinicmeded.com]

Prevention

  • Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets[books.google.com]
  • No vaccine is yet available to prevent hepatitis C. Most people recover from hepatitis, and the disease is often preventable. However, it is still considered a serious health risk because it can: Destroy liver tissue.[my.clevelandclinic.org]
  • Prevention : No vaccine is available. Prevention methods include: Abstain from sex or practice safer sex, including using latex or polyurethane condoms. Do not share injection drug equipment.[uhs.umich.edu]
  • However, later administration attenuates the clinical expression of HAV infection. 12 These recommendations for the prevention of hepatitis A are advocated by the Centers for Disease Control and Prevention (CDC).[clevelandclinicmeded.com]

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