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Noninfiltrating Intraductal Carcinoma


Presentation

  • We present a unique case of synchronous pure intraductal carcinoma of the breast (DCIS) and invasive carcinoma of ectopic breast tissue of the vulva. A 53-year-old woman presented with a 2-cm nodule in left labium major of the vulva.[ncbi.nlm.nih.gov]
Sepsis
  • […] associated with this congenital abnormality is currently 16 As the prenatal diagnosis of posterior urethral valves may be difficult, most deaths occur in newborns with severe bilateral renal dysplasia, pulmonary hypoplasia, electrolyte imbalances, or sepsis[abdominalkey.com]
Epigastric Pain
  • A 67-year-old Japanese man with a complaint of epigastric pain was examined by endoscopic retrograde pancreatography, which demonstrated multiple dilated branches of the pancreatic duct in the body and tail of the pancreas.[ncbi.nlm.nih.gov]
  • CASE PRESENTATION A Seventeen-year-old woman was admitted to our surgical department due to epigastric pain associated with vomiting.[pancreas.imedpub.com]
Intestinal Disease
  • disease M9765/1 Monoclonal gammopathy M9766/1 Angiocentric immunoproliferative lesion M9767/1 Angioimmunoblastic lymphadenopathy M9768/1 T-gamma lymphoproliferative disease (M980-M980) Leukaemias NOS M9800/3 Leukaemia NOS M9801/3 Acute leukaemia NOS[celsius.lshtm.ac.uk]
Nipple Discharge
  • In current clinical practice, the use of nipple discharge cytology as a screening and diagnostic tool for breast carcinoma is largely supplemental; however, this case illustrates the occasional utility of nipple discharge cytology in the diagnosis of[ncbi.nlm.nih.gov]
  • PH1216 Intraductal Papillomas Non-cancerous wart-like growths that have grown inside the breast, often involving the large milk ducts near the nipple, causing bloody nipple discharge.[lifeworkpotential.com]
  • discharge). 7% of serous and 14% of blood nipple discharges are malignant.[radnotes.co.nz]
  • discharge from a single duct the most common cause of spontaneous bloody nipple discharge from a single duct palpable subareolar mass; may be nonpalpable [typically small, but may grow to several centimeters] Mammographic Features of an Intraductal Papilloma[quizlet.com]
Nipple Retraction
  • Retraction 203 Ulceration 206 Cutaneous Metastases 207 Lesions That Arise Outside the Ducts and Lobules 213 Skin Tumors 218 Calcifications of the Epidermis and Subcutaneous Tissue 222 Nipple Changes 223[books.google.com]
  • Nipple retraction Lymphatics - involved - block the local area of skin drainage  lymphedema , skin thickening. Tethering of the skin to the breast by Cooper ligaments  peau d'orange . Mammography  Radiodense mass 30.[slideshare.net]
  • Local lymphatic occlusion causes nipple retraction.[radnotes.co.nz]
Breast Mass
  • (primarily breast masses) 14 2/181 (1.1) 1/2 (50) Pijnappel et al., 2004 [ 22 ] Breast mass and calcifications only 14 or 18 8/128 (6.3) 5/8 (62.5) Crystal et al., 2005 [ 21 ] Breast masses 14 6/715 (0.8) 4/6 (66.7) Sauer et al., 2005 [ 20 ] Breast masses[e-ultrasonography.org]
  • Recognize US and mammographic features that support or preclude biopsy of an echogenic breast mass. •. Discuss clinical situations in which biopsy of an echogenic breast mass can be safely avoided. •.[pubs.rsna.org]
  • Biopsy provides definitive diagnosis PASH pseudoangiomatous stromal hyperplasia represents a focal overgrowth of stromal connective tissue that forms a breast mass the stromal tissue contains avascular, lit-like cavities that look similar to vascular[quizlet.com]
  • Before surgery, all patients in this study were subjected to full history taking, thorough clinical examination, fine needle aspiration cytology (FNAC) or excision biopsy from the breast mass for pathological examination, laboratory investigations including[scirp.org]
  • It occurs in patients in their 30s and 40s who present with a breast mass, and by imaging, they are round, oval or lobulated [ 42 ].[journals.sagepub.com]

Treatment

  • Has a known additional malignancy that is progressing or requires active treatment.[clinicaltrials.ucsf.edu]
  • Survival rates which were similar for patients with DCIS regardless of form of local treatment were better than that observed for negative node patients with invasive cancer enrolled in protocol 6.[ncbi.nlm.nih.gov]

Prognosis

  • Either stellate (with focal necrosis, very poor prognosis) or circular/oval (1/3, better prognosis). Molecular classes correlate with prognosis and response to therapy: Luminal A (40-55%) – ER positive and HER2/neu negative.[radnotes.co.nz]
  • KEYWORDS: diagnostic criteria; intraductal carcinoma of the prostate; prognosis [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov]
  • Excellent prognosis. 41. INVASIVE PAPILLARY & MICROPAPILLARY CARCINOMA Rare - 1% or fewer of all invasive cancers. More commonly seen in DCIS. INVASIVE PAPILLARY CA. ER positive. Favorable prognosis. INVASIVE MICROPAPILLARY CA.[slideshare.net]
  • Histo path of infiltrating breast carcinoma anaplastic duct appear in epithelial cells appear in masses that invade the stroma pathogenesis of infiltrating breast carcinoma fibrous reaction responsible for hard, palpable mass Epidemiology and prognosis[brainscape.com]

Etiology

  • […] anatomy and histology blood blood supply cerebrospinal fluid chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology[ncbi.nlm.nih.gov]
  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • […] the most common benign solid breast tumor noninfiltrative lesion compresses surrounding tissues as it grows within normal tissue planes the pseudocapsule of a fibroadenoma represents the leading edge of compressed breast tissue surrounding the mass Etiology[quizlet.com]
  • Furthermore, it seems that the connection between these two diseases may not just be etiologic and there may be synergism between the two cancers after tumorigenesis has occurred.[ejbc.kr]

Epidemiology

  • […] options Subheadings: analysis anatomy and histology blood blood supply cerebrospinal fluid chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology[ncbi.nlm.nih.gov]
  • Expert authors in this issue review this topic in articles such as: Applications for Breast MRI; Lobular Neoplasia; Epidemiology of Breast Cancer; Percutaneous Ablation of Breast Tumors; Triple Negative Breast Cancer and the Basal Breast Cancer Subtype[books.google.ro]
  • EPIDEMIOLOGY AND CLINICAL FEATURES LCIS is most frequently diagnosed in women aged 40 to 55 years ( 4, 11 ).[oncohemakey.com]
  • Availability of data and materials The datasets analyzed during the current study are available on the Surveillance, Epidemiology, and End Results Program.[bmcmedinformdecismak.biomedcentral.com]
Sex distribution
Age distribution

Pathophysiology

  • Diagnosis of the two conditions in a single patient is often thought to be coincidental, but there is evidence supporting a possible pathophysiological connection involving a common genetic background or etiologic factor, or possibly, one disease causes[ejbc.kr]

Prevention

  • […] imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology genetics history immunology metabolism microbiology mortality nursing organization and administration parasitology pathology physiology physiopathology prevention[ncbi.nlm.nih.gov]
  • […] high-grade (grade II-III), palpable mass, hormone receptor negative (less than 1%), Her2 positive, young age (less than 45 years old), and large size (greater than 5 cm) Patients with a history of tamoxifen and/or aromatase inhibitor use for treatment or prevention[clinicaltrials.ucsf.edu]
  • A prominent physician at a San Francisco hospital recommended a course of preventative treatment—just to be safe. But Ms. Adams did not wish to undergo preventative chemotherapy or radiation.[ptreyeslight.com]
  • Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 12 participants Allocation: Non-Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Preventing[clinicaltrials.gov]
  • It may be argued that those invasive cancers, with their potential for dissemination, could have been prevented had the primary tumor been treated by mastectomy.[nejm.org]

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