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Nontuberculous Mycobacteria


Presentation

  • He subsequently expired within one month of presentation. CONCLUSIONS We present a unique case of high-grade anterior mediastinum ESOS and a review of the literature regarding all documented cases of ESOS to date.[ncbi.nlm.nih.gov]
  • CONCLUSION: The results have shown that NTM and MTB are present in the intestines of the patients booked for colonoscopy at the University Teaching Hospital in Lusaka, but their presence is not related to presenting symptoms.[ncbi.nlm.nih.gov]
  • We describe three patients with multifocal osteomyelitis caused by Mycobacterium avium and a family history of one or more first degree family members diagnosed with various clinical presentations of infections with nontuberculous mycobacteria.[ncbi.nlm.nih.gov]
  • Three cases of nontuberculous mycobacterial adenitis are presented, with clinical response to antibiotics before surgery.[ncbi.nlm.nih.gov]
  • We report 2 cases in sisters who were diagnosed with a genetic defect caused by a new mutation in Interleukin-12 receptor β1 chain (IL12Rβ1) leading to different clinical presentations and responses to therapy.[ncbi.nlm.nih.gov]
Physician
  • We retrospectively reviewed all cases (n 4) of presumptively diagnosed hot tub lung in immunocompetent individuals at the various physician practices in Springfield, Illinois, during 2001-2005.[ncbi.nlm.nih.gov]
  • To assist in the timely diagnosis and treatment of these infections, we aim to promote greater awareness among physicians who are likely to encounter such patients.[ncbi.nlm.nih.gov]
Localized Pain
  • The main patient complaint was local pain but some presented with systemic symptoms such as fever and malaise. Biopsies reported granulomatous chronic inflammation in the majority of cases.[ncbi.nlm.nih.gov]
Rapidly Progressive Glomerulonephritis
  • To our knowledge, this is the first report of rapidly progressive glomerulonephritis associated with NTM infection.[ncbi.nlm.nih.gov]
Aspiration
  • Histopathologic examination of aspirates or biopsy specimens from involved areas and staining and culture for mycobacteria are essential for diagnosis.[ncbi.nlm.nih.gov]
Otalgia
  • The rates of granulation tissue, otalgia, and facial palsy were 90.9%, 31.8%, and 9.1%, respectively. Soft tissue attenuation via imaging studies was demonstrated in all of the middle ear cavities.[ncbi.nlm.nih.gov]
Facial Skin Lesion
  • BACKGROUND: Nontuberculous mycobacteria rarely cause facial skin lesions in immunocompetent children. AIM: I describe the clinical features and treatment of nontuberculous mycobacteria facial lesions.[ncbi.nlm.nih.gov]
Facial Scar
  • Nonsurgical treatment is preferable, because surgical excision of the cutaneous lesions might lead to undesirable visible facial scars. 2016 Wiley Periodicals, Inc.[ncbi.nlm.nih.gov]
Facial Pain
  • Clinically, it is characterized by the triad of suppurative otitis media, deep facial pain, and abducens palsy. Most of the Gradenigo syndrome cases that have been reported in the literature were caused by pyogenic bacteria.[ncbi.nlm.nih.gov]
Neglect
  • The impact of NTM species diversity on clinical outcome is so far neglected in most of the clinical settings.[ncbi.nlm.nih.gov]

Treatment

  • […] the treatment of these individuals.[ncbi.nlm.nih.gov]
  • Treatment was started in 164 patients (34.6%). Among these 164 patients, 16 experienced changes of NTM species during or within 2 years of treatment completion.[ncbi.nlm.nih.gov]
  • Recent consensus guidelines for treatment of NTM in CF have provided a guide for the CF community, however research is lagging regarding accuracy of our diagnostic abilities and treatment efficacy.[ncbi.nlm.nih.gov]
  • Surgery, which is the mainstay of treatment, should be complemented with antibiotics. In those without temporal bone osteomyelitis, antibiotic treatment can be stopped after a dry ear is achieved.[ncbi.nlm.nih.gov]
  • The rarity of these infections in the parotid region and the lack of specific guidelines pose a treatment challenge to the clinician.[ncbi.nlm.nih.gov]

Prognosis

  • PNTMI was not identified as a significant factor associated with prognosis by either univariate or multivariate analysis (hazard ratio [HR]   0.950 and HR   0.948, respectively). Georg Thieme Verlag KG Stuttgart · New York.[ncbi.nlm.nih.gov]
  • KEYWORDS: chronic pulmonary aspergillosis; nontuberculous mycobacteria; outcome; prognosis[ncbi.nlm.nih.gov]

Etiology

  • Currently, NTM are recognized as etiological agents of several respiratory and extra-respiratory infections of immune-competent individuals.[ncbi.nlm.nih.gov]
  • NTM probably play an important role in the etiology of TB-like diseases in Zambia.[ncbi.nlm.nih.gov]

Epidemiology

  • MeSH terms, Substances MeSH terms Bacterial Proteins/genetics Chaperonin 60/genetics Cross Infection/epidemiology* Cross Infection/microbiology DNA, Bacterial/genetics Hospitals* Humans Iran/epidemiology Mycobacterium Infections, Nontuberculous/epidemiology[ncbi.nlm.nih.gov]
  • Further characterization of NTM epidemiology is increasingly important as percentages of immunocompromised individuals and the elderly increase in the U.S. Published by Elsevier Ltd.[ncbi.nlm.nih.gov]
  • AIMS: To analyze the epidemiological and laboratory profiles of patients with isolation of nontuberculous mycobacteria (NTM) over one decade.[ncbi.nlm.nih.gov]
  • In order to provide an overview of NTM, as well as recent epidemiological trends, all studies addressing NTM in the Middle East from 1984 to 2014 were reviewed.[ncbi.nlm.nih.gov]
  • KEYWORDS: Canada; Mycobacterium avium complex; NTM; Ontario; bacteria; epidemiology; infection; nontuberculous mycobacteria; nontuberculous mycobacterium; tuberculosis and other mycobacteria[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Prevention

  • Waterborne NTM infection affects susceptible patients through common, preventable exposure routes.[ncbi.nlm.nih.gov]
  • Primary prevention of this disease relies on ventilation and good use practices. Secondary prevention of this disease requires education of both the general public and clinicians to allow for the early diagnosis of this disease.[ncbi.nlm.nih.gov]
  • Participants identified as top research priorities the prevention of NTM infection; approval of more effective treatments with fewer side effects and easier administration; understanding the best chest physiotherapy methods; validating and using tools[ncbi.nlm.nih.gov]
  • In May 2001, union and management representatives requested assistance from CDC's National Institute for Occupational Safety and Health (NIOSH) in determining the cause of the illnesses and preventing further illness in employees.[ncbi.nlm.nih.gov]
  • Recent publications also raise the possibility of improved control of PNTM through enhanced adherence to current treatment guidelines as well as new approaches to treatment and even prevention.[ncbi.nlm.nih.gov]

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