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Occipital Lobe Tumor

Neoplasm of Occipital Lobe of Brain

Tumors developing in the posterior aspect of the brain are termed occipital lobe tumors. Both primary and secondary (metastatic) lesions were recognized in clinical practice and tumors of neural, skeletal, mesenchymal, and vascular origins have all been described. The principal symptom of an occipital lobe tumor is visual disturbance, with the severity depending on the extent of tumor spread. Headaches and seizures are additional complaints. The diagnosis rests on clinical criteria and a comprehensive imaging follow-up, mainly through computed tomography (CT) and gadolinium-enhanced magnetic resonance imaging (MRI).


Presentation

Occipital lobe tumors encompass numerous neoplastic processes of different etiologies and clinical stages. The most important primary brain tumors that have been identified in the occipital lobe are tumors of neuroepithelial tissue (mainly gliomas, particularly low-grade), but vascular (such as hemangioendothelioma), mesenchymal (myxomas), and several other tumor types were also documented in the literature [1] [2] [3] [4]. Similarly to other brain tumors, headaches and seizures are common symptoms in this patient population [5] [6]. However, a suspicion toward an occipital lobe tumor can be made in the presence of visual disturbances [1] [5]. Visual hallucinations (that may or may not be accompanied by seizures) are some of the most frequent findings, presenting as light flashes consisting of different shapes, whereas prosopagnosia (inability to recognize previously known faces) is an important component of the clinical presentation [2]. Furthermore, patients with severe and expanding tumors that cause the destruction of one of the occipital lobes will suffer from homonymous hemianopia on the contralateral side [2]. When both lobes are affected, cortical blindness that is negated by patients (known as Anton syndrome) may be encountered [2]. In these cases, patients clearly state that they can see, despite a clinically confirmed absence of vision [2].

Vascular Disease
  • This second volume covers tumors, the phacomatoses, and vascular disease. Volume 1 covers the visual sensory system, the autonomic nervous system, the ocular motor system, the eyelid, facial pain and headache, and nonorganic disease.[books.google.com]
  • Dementia due to subcortical ischemic vascular disease. Clin Cornerstone 2001 ; 3 : 40 –51 Pasquier F, Henon H, Leys D. Relevance of white matter changes to pre- and poststroke dementia.[ajnr.org]
Photophobia
  • Her headache was characterized by recurrent episodes of visual aura confined to the left visual field followed by right hemicranial throbbing headaches accompanied by nausea, photophobia, and phonophobia.[miami.pure.elsevier.com]
Scotoma
  • Scotoma The Peristriate region of the occipital lobe is involved in visuospatial processing, discrimination of movement and color discrimination.[braininjury-explanation.com]
Facial Pain
  • Volume 1 covers the visual sensory system, the autonomic nervous system, the ocular motor system, the eyelid, facial pain and headache, and nonorganic disease.[books.google.com]
Visual Hallucination
  • Visual hallucinations (that may or may not be accompanied by seizures) are some of the most frequent findings, presenting as light flashes consisting of different shapes, whereas prosopagnosia (inability to recognize previously known faces) is an important[symptoma.com]
  • Occipital lesions can cause visual hallucinations. Lesions in the parietal-temporal-occipital association area are associated with color agnosia, movement agnosia, and agraphia.[en.wikipedia.org]
Compulsive Behavior
  • Presentation varies from small motor tics , unusual perceptual disturbances, time-distortion, derealization, panic-like sxs, compulsive behaviors, catatonic variants, atypical aggressive outbursts, obsessions, and much more.[healthtap.com]
Headache
  • Similarly to other brain tumors, headaches and seizures are common symptoms in this patient population. However, a suspicion toward an occipital lobe tumor can be made in the presence of visual disturbances.[symptoma.com]
  • KW - brain tumor KW - headache KW - migraine with aura UR - UR - U2 - 10.1046/j.1526-4610.1996.3601049.x DO - 10.1046/j.1526-4610.1996.3601049.x M3 - Article VL - 36 SP - 49 EP - 52 JO - Headache T2 - Headache JF - Headache SN - 0017-8748 IS - 1 ER -[miami.pure.elsevier.com]
  • When the headache returns, the concern is if the tumor is back or if it is precipitating migraine headaches. Migraine headaches can be precipitated by structural lesions(such as tumors), but care must be taken to rule out other causes.[medhelp.org]
  • This case illustrates that headache fulfilling the International Headache Society (IHS) criteria for migraine with typical aura can occur in association with an occipital lobe tumor.[ncbi.nlm.nih.gov]
  • In conjunction with the headache I would have congestion and an intermediate earache. I thought it was my sinuses so I would take sinus headache medication but that did not stop the pain.[healthboards.com]
Aura
  • @article{2fe013b57d98484f8a8f34febf60ca69, title "Occipital lobe tumor presenting as migraine with typical aura", abstract "We report the case of a 60-year-old woman in whom migraine with typical aura heralded the presence of an occipital lobe tumor.[miami.pure.elsevier.com]
  • Abstract We report the case of a 60-year-old woman in whom migraine with typical aura heralded the presence of an occipital lobe tumor.[ncbi.nlm.nih.gov]
  • A simple partial seizure can be a precursor to a larger seizure and then it is called an aura. A complex partial seizure affects a larger part of the hemisphere and the person may lose consciousness.[radiologyassistant.nl]
Throbbing Headache
  • Her headache was characterized by recurrent episodes of visual aura confined to the left visual field followed by right hemicranial throbbing headaches accompanied by nausea, photophobia, and phonophobia.[miami.pure.elsevier.com]
Sinus Headache
  • I thought it was my sinuses so I would take sinus headache medication but that did not stop the pain.[healthboards.com]
  • He finally accepted it wasn't sinus headaches only when he started violently vomitting for 2 days before going to the hospital. On December 1st, a CT and MRI confirmed a 3.8cm mass in his occipital lobe.[inspire.com]
Homonymous Hemianopsia
  • Clinical significance [ edit ] If one occipital lobe is damaged, the result can be homonymous hemianopsia vision loss from similarly positioned "field cuts" in each eye. Occipital lesions can cause visual hallucinations.[en.wikipedia.org]

Workup

The diagnostic workup of patients in whom an occipital lobe tumor is suspected should start by conducting a thorough patient history, which will assess the onset of complaints, their progression, as well as severity. If patients report progressive visual symptoms (with or without headaches or epilepsy), a thorough examination of visual fields and acuity should be performed in order to assess the localization of the deficits. After sufficient clinical evidence has been gathered, imaging studies need to be employed; these are the gold standard for diagnosing brain tumors [1] [4]. MRI, using T1 and T2-weighted studies with gadolinium as a contrast, as well as fluid-attenuated inversion-recovery (FLAIR) sequence imaging, is considered to be the first-line study that allows identification of the exact location and the characteristics of the lesion [1] [3] [4] [6] [7]. When MRI is contraindicated (for example, in the presence of foreign metallic bodies or pacemakers), CT of the endocranium serves as an alternative [1] [4]. More advanced techniques are indicated when further diagnosis and treatment planning is required, such as functional MRIs (fMRI), MR proton spectroscopy, single photon emission tomography (SPECT), positron-emission tomography (PET), or visual evoked potential [6] [8] [9]. A definite classification of the tumor type is made from imaging findings and biopsy samples obtained either preoperatively or postoperatively [1] [4].

Treatment

  • The third part reviews the surgical treatments for various neuro-related problems, including trauma, brain tumors, pain, and motor disorders.[books.google.com]
  • Coverage includes major updates on genetics of diseases, new diagnostic techniques, and the newest treatment options. This second volume covers tumors, the phacomatoses, and vascular disease.[books.google.com]
  • Treatments Treatment for an occipital lobe tumor is determined by where it is located.[healthyliving.azcentral.com]
  • More advanced techniques are indicated when further diagnosis and treatment planning is required, such as functional MRIs (fMRI), MR proton spectroscopy, single photon emission tomography (SPECT), positron-emission tomography (PET), or visual evoked potential[symptoma.com]
  • No facial or swallowing issues. thank you (all of you) for answering. i guess with his mass, he's heard several different courses of treatment that are vastly different. doc #1 - take a biopsy - get it out now. doc #2 - wait. then one said he may have[anausa.org]

Prognosis

  • References Similar Posts: Related posts: Appendix Cancer - Symptoms, Survival Rate, Prognosis, Treatment, Pilocytic Astrocytoma - Prognosis, Survival Rate and Treatment Merkel Cell Carcinoma - Pictures, Prognosis, Survival Rate, Treatment Glioblastoma[cancerwall.com]
  • Prognosis "Prognosis" is the medical term for a prediction of life expectancy. Keep in mind that these predictions are estimates.[abta.org]
  • The prognosis for vision with optic pathway gliomas is variable. Some of these remain stationary both in terms of their deleterious effect on vision and of their size on MRI.[childhoodbraintumor.org]
  • Anaplastic astrocytoma: diagnosis, prognosis, and management. Semin Oncol. 2004;31:618-34. Jennings MT, Ivengar S. Pharmacotherapy of malignant astrocytomas of children and adults: current strategies and future trends. CNS Drugs. 2001;15:719-43.[rarediseases.org]
  • If the meningioma does begin to grow, doctors may intervene with surgery, or radiation if the tumor is in a hard to access area, and the prognosis is ‘excellent’ if the tumor is removed entirely.[foxnews.com]

Etiology

  • Occipital lobe tumors encompass numerous neoplastic processes of different etiologies and clinical stages.[symptoma.com]
  • Occipital lobe epilepsies are etiologically idiopathic, symptomatic, or cryptogenic. [8] Symptomatic occipital seizures can start at any age, as well as any stage after or during the course of the underlying causative disorder.[en.wikipedia.org]
  • We have taken a pragmatic approach to this, including all of the lesions in the scoring system because existing pathologic evidence suggests that these lesions share common etiologic mechanisms.[ajnr.org]
  • MTS is the most common cause of partial complex epilepsy in adults and is also the most common etiology in young adult patients undergoing surgery.[radiologyassistant.nl]

Pathophysiology

  • Penning Published 2015 in BMC Research Notes DOI: 10.1186/s13104-015-1628-4 In the last decade canine models have been used extensively to study genetic causes of neurological disorders such as epilepsy and Alzheimer’s disease and unravel their pathophysiological[pdfs.semanticscholar.org]
  • This provides an ideal forum for students to gain a deeper understanding of the pathophysiology of movement disorders, recognizing important clinical findings, identifying potential DBS candidates and the perioperative management of this population.[jefferson.edu]

Prevention

  • الصفحة 1607 - Centers for Disease Control and Prevention: 1994 Revised Classification System for Human Immunodeficiency Virus Infection in Children Less Than 13 Years of Age, MMWR, 43, 1-19, No. ‏[books.google.com]
  • The headaches increased in frequency over 4 months despite a number of medications known to prevent attacks of migraine. A low-grade right occipital lobe tumor was eventually discovered on MR scan.[miami.pure.elsevier.com]
  • From the symptoms/history you describe I would recommend that you start a migraine preventative medication such as elavil 10mg-25mg at night, and get the EEG previously mentioned.[medhelp.org]
  • Página 310 - A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients. ‎[books.google.es]

References

Article

  1. Perkins A, Liu G. Primary Brain Tumors in Adults: Diagnosis and Treatment. Am Fam Physician. 2016;93(3):211-217.
  2. Pan E, Prados MD. Clinical Presentation. In: Kufe DW, Pollock RE, Weichselbaum RR, et al., editors. Holland-Frei Cancer Medicine. 6th edition. Hamilton (ON): BC Decker; 2003.
  3. Verma A, Rosenfeld V, Forteza A, Sharma KR. Occipital lobe tumor presenting as migraine with typical aura. Headache. 1996;36(1):49-52.
  4. Amit A, Bhake A, Banode P, Singh BR. Malignant hemangioendothelioma of occipital bone. Chin J Cancer Res. 2012;24(2):161-163.
  5. Kawatra M, Bhandari V, Phatak S, Kulkarni D. Primary occipital myxoma: A rare case report. J Pediatr Neurosci. 2013;8(2):129-131.
  6. Schneider T, Mawrin C, Scherlach C, Skalej M, Firsching R. Gliomas in Adults. Dtsch Arztebl Int. 2010;107(45):799-808.
  7. Tatsuzawa K, Owada K, Sasajima H, Yamada K, Mineura K. Surgical strategy of brain tumors adjacent to the optic radiation using diffusion tensor imaging-based tractography. Oncology Letters. 2010;1(6):1005-1009.
  8. Roux FE, Ibarrola D, Lotterie JA, Chollet F, Berry I. Perimetric visual field and functional MRI correlation: implications for image-guided surgery in occipital brain tumours. J Neurol Neurosurg Psychiatry. 2001;71:505–514.
  9. Lacerda S, Law M. Magnetic resonance perfusion and permeability imaging in brain tumors. Neuroimaging Clin N Am. 2009;19(4):527-557.

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Last updated: 2018-06-22 02:53