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Oculoglandular Listeriosis

Oculo-Glandular Listeriosis


Presentation

  • They are present worldwide in the environment and in the gut of humans, nonhuman mammals, birds, arachnids, and crustaceans. There are several species of Listeria, but L. monocytogenes is the primary pathogen in humans.[msdmanuals.com]
  • Egg-Yolk Agar : Lecithin is present to test for lecithinase. Double-Zone of hemolysis. Very fast replicating Alpha Toxin : Lecithinase, responsible for zone of incomplete hemolysis Beta Toxin : Cytotoxin, responsible for necrotizing enteritis.[kumc.edu]
Cervical Lymphadenopathy
  • lymphadenopathy; intestinal – intestinal pain, vomiting, and diarrhea; pneumonic – primary pleuropulmonary disease; typhoidal – febrile illness without early localizing signs and symptoms.[bccdc.ca]
Fever
  • Symptoms include fever and chills, headache, upset stomach and vomiting. Treatment is with antibiotics. Anyone can get the illness. But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems.[icdlist.com]
  • Clinical manifestations include fever, muscle pain, respiratory distress, nausea, diarrhea, neck stiffness, irritability, seizures, and lethargy.[icd10data.com]
  • Common symptoms: fever, watery diarrhea, nausea, headache, myalgias, joint aches Severe headache, fever, stiff neck, seizures Irritability, lethargy, poor feeding in neonates Illness dur...[5minuteconsult.com]
  • Streptococcus Pyogenes (Group A) Scarlet Fever Pyoderma (Impetigo, Erysipela) Pharyngitis Bacteremia Non-Suppurative: Rheumatic Fever, Glomerulonephritis GRAM( ) COCCI in chains of 8 to 4 BACITRACIN-SENSITIVE CATALASE (-) : Does not bubble H 2 O 2 in[kumc.edu]
  • Chills and fever are due to bacteremia. In immunosuppressed individuals it can produce serious illness, leading to meningitis. It is one of the leading causes of bacterial meningitis in patients with cancer and in renal transplant recipients.[microrao.com]
Sepsis
  • Listeriosis infection Oculoglandular listeriosis Sepsis due to Listeria monocytogenes 027.0 Excludes congenital listeriosis ( 771.2 ) Applies To Infection by Listeria monocytogenes Septicemia by Listeria monocytogenes Use Additional Use additional code[icd9data.com]
  • A32.9 Listeriosis, unspecified P37.2 Neonatal (disseminated) listeriosis A32.89 Other forms of listeriosis A32.11 Listerial meningitis A32.81 Oculoglandular listeriosis A32.7 Listerial sepsis A32... Listeriosis is most common at the extremes of age.[5minuteconsult.com]
  • Codes A32 Listeriosis A32.0 Cutaneous listeriosis A32.1 Listerial meningitis and meningoencephalitis A32.11 Listerial meningitis A32.12 Listerial meningoencephalitis A32.7 Listerial sepsis A32.8 Other forms of listeriosis A32.81 Oculoglandular listeriosis[icd10data.com]
  • Exposure on vaginal delivery results in the late onset disease resulting in meningitis or meningo-encephalitis with sepsis within 2 to 3 weeks. Adult Disease: Exposure to the organism can lead to asymptomatic miscarriage or disease in humans.[microrao.com]
Chills
  • Symptoms include fever and chills, headache, upset stomach and vomiting. Treatment is with antibiotics. Anyone can get the illness. But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems.[icdlist.com]
  • Symptoms include fever and chills, headache, upset stomach and vomiting. Anyone can get the illness. But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems.[icd10data.com]
  • Chills and fever are due to bacteremia. In immunosuppressed individuals it can produce serious illness, leading to meningitis. It is one of the leading causes of bacterial meningitis in patients with cancer and in renal transplant recipients.[microrao.com]
Pain
  • […] regional lymphadenopathy; glandular – regional lymphadenopathy with no ulcer; oculoglandular – conjunctivitis with preauricular lymphadenopathy; oropharyngeal – stomatitis or pharyngitis, or tonsillitis and cervical lymphadenopathy; intestinal – intestinal pain[bccdc.ca]
  • Clinical manifestations include fever, muscle pain, respiratory distress, nausea, diarrhea, neck stiffness, irritability, seizures, and lethargy.[icd10data.com]
  • Hemophilus Ducreyi CHANCROID : Painful Purulent Exudate Non-indurated GRAM(-) ROD Chocolate Agar, but difficult to grow.[kumc.edu]
Weakness
  • But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems.[icdlist.com]
Respiratory Distress
  • Clinical manifestations include fever, muscle pain, respiratory distress, nausea, diarrhea, neck stiffness, irritability, seizures, and lethargy.[icd10data.com]
Vomiting
  • Symptoms include fever and chills, headache, upset stomach and vomiting. Treatment is with antibiotics. Anyone can get the illness. But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems.[icdlist.com]
  • […] lymphadenopathy; glandular – regional lymphadenopathy with no ulcer; oculoglandular – conjunctivitis with preauricular lymphadenopathy; oropharyngeal – stomatitis or pharyngitis, or tonsillitis and cervical lymphadenopathy; intestinal – intestinal pain, vomiting[bccdc.ca]
  • Symptoms include fever and chills, headache, upset stomach and vomiting. Anyone can get the illness. But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems.[icd10data.com]
  • Bacillus Cereus Food Poisoning: Refried beans and rice Opportunistic nosocomial bacteremia GRAM( ) ROD Penicillin-Resistant -- chains of rods gamma-Phage resistant Emetic Toxin (early vomiting) Diarrheal Toxin (late diarrhea, heat resistant) beta-Lactamase[kumc.edu]
Diarrhea
  • […] glandular – regional lymphadenopathy with no ulcer; oculoglandular – conjunctivitis with preauricular lymphadenopathy; oropharyngeal – stomatitis or pharyngitis, or tonsillitis and cervical lymphadenopathy; intestinal – intestinal pain, vomiting, and diarrhea[bccdc.ca]
  • Yersinia Enterocolitica (Enterobacteriaceae) Watery Diarrhea Mesenteric Adenitis (5-15 yrs old) Terminal Ileitis (15-20 yrs old) Diarrhea HLA-B27 arthritis GRAM(-) ROD Enrichment broth used before collecting, due to low number of collecting organisms.[kumc.edu]
  • Common symptoms: fever, watery diarrhea, nausea, headache, myalgias, joint aches Severe headache, fever, stiff neck, seizures Irritability, lethargy, poor feeding in neonates Illness dur...[5minuteconsult.com]
  • Clinical manifestations include fever, muscle pain, respiratory distress, nausea, diarrhea, neck stiffness, irritability, seizures, and lethargy.[icd10data.com]
Food Poisoning
  • Ingestion of contaminated dairy products and raw vegetables (food poisoning) b. Direct contact, antepartum and intrapartum from mother to child, especially during abortions c. From infected animals to butchers and slaughterhouse workers.[microrao.com]
  • Bug Name Manifestations Identifying Properties Culture / Tests Virulence Vaccine / Rx Staphylococcus Aureus Food Poisoning Scalded Skin Syndrome TSS Syndrome Furuncle, Carbuncle Bacteremia, Osteomyelitis, Endocarditis GRAM( ) COCCI in clusters Catalase[kumc.edu]
Nausea
  • Common symptoms: fever, watery diarrhea, nausea, headache, myalgias, joint aches Severe headache, fever, stiff neck, seizures Irritability, lethargy, poor feeding in neonates Illness dur...[5minuteconsult.com]
  • Clinical manifestations include fever, muscle pain, respiratory distress, nausea, diarrhea, neck stiffness, irritability, seizures, and lethargy.[icd10data.com]
Ulcer
  • […] with regional lymphadenopathy; glandular – regional lymphadenopathy with no ulcer; oculoglandular – conjunctivitis with preauricular lymphadenopathy; oropharyngeal – stomatitis or pharyngitis, or tonsillitis and cervical lymphadenopathy; intestinal –[bccdc.ca]
  • Shigella (Enterobacteriaceae) DYSENTERY -- ulcerative colitis. Communicable and very low infective dose. GRAM(-) ROD NON-MOTILE NON-LACTOSE FERMENTING Special transport medium required.[kumc.edu]
Myalgia
  • Common symptoms: fever, watery diarrhea, nausea, headache, myalgias, joint aches Severe headache, fever, stiff neck, seizures Irritability, lethargy, poor feeding in neonates Illness dur...[5minuteconsult.com]
Suggestibility
  • These data, like those already appearing in the literature, suggest that intravenous ampicillin may be the therapy of choice, from the standpoint of both superior efficacy and relative lack of toxicity.[nejm.org]
Meningism
  • Listeria primarily causes infections of the central nervous system (meningitis, meningoencephalitis, brain abscess, cerebritis) and bacteremia in those who are immunocompromised, pregnant women, and those at the extremes of age (newborns and the elderly[icd.codes]
  • ICD code(s) ICD-10 code(s) A32 Listeriosis ( includes listerial foodborne infection; excludes neonatal (disseminated) listeriosis P37.2) A32.1 Listerial meningitis and meningoencephalitis (Listerial: meningitis (G01); meningoencephalitis (G05.0) A32.7[canada.ca]
  • […] by Listeria monocytogenes Use Additional Use additional code to identify manifestations, as meningitis ( 320.7 ) ICD-9-CM Volume 2 Index entries containing back-references to 027.0 :[icd9data.com]
  • Gram positive bacterial infection with the genus listeria including listeria meningitis which causes clinical manifestations including fever, altered mentation, headache, meningeal signs, focal neurologic signs, and seizures.[icd10data.com]
  • For treatment of neonatal meningitis, see Neonatal Bacterial Meningitis : Organism-specific antibiotic therapy.[msdmanuals.com]
Headache
  • Symptoms include fever and chills, headache, upset stomach and vomiting. Treatment is with antibiotics. Anyone can get the illness. But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems.[icdlist.com]
  • Common symptoms: fever, watery diarrhea, nausea, headache, myalgias, joint aches Severe headache, fever, stiff neck, seizures Irritability, lethargy, poor feeding in neonates Illness dur...[5minuteconsult.com]
  • Symptoms include fever and chills, headache, upset stomach and vomiting. Anyone can get the illness. But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems.[icd10data.com]
  • Chlamydia Pneumonia (Chlamydiaceae) Walking Pneumonia: infects columnar epithelium of upper airway OBLIGATE INTRACELLULAR PARASITE No Peptidoglycan Layer Tetracycline Chlamydia Psittaci (Chlamydiaceae) PSITTACOSIS : Dry hacking cough, severe CNS symptoms (headache[kumc.edu]
Irritability
  • Common symptoms: fever, watery diarrhea, nausea, headache, myalgias, joint aches Severe headache, fever, stiff neck, seizures Irritability, lethargy, poor feeding in neonates Illness dur...[5minuteconsult.com]
  • Clinical manifestations include fever, muscle pain, respiratory distress, nausea, diarrhea, neck stiffness, irritability, seizures, and lethargy.[icd10data.com]
Seizure
  • Clinical manifestations include fever, muscle pain, respiratory distress, nausea, diarrhea, neck stiffness, irritability, seizures, and lethargy.[icd10data.com]
  • Common symptoms: fever, watery diarrhea, nausea, headache, myalgias, joint aches Severe headache, fever, stiff neck, seizures Irritability, lethargy, poor feeding in neonates Illness dur...[5minuteconsult.com]
Lethargy
  • Common symptoms: fever, watery diarrhea, nausea, headache, myalgias, joint aches Severe headache, fever, stiff neck, seizures Irritability, lethargy, poor feeding in neonates Illness dur...[5minuteconsult.com]
  • Clinical manifestations include fever, muscle pain, respiratory distress, nausea, diarrhea, neck stiffness, irritability, seizures, and lethargy.[icd10data.com]

Workup

Listeria Monocytogenes
  • The ICD code A32 is used to code Listeriosis Listeriosis is a bacterial infection most commonly caused by Listeria monocytogenes, although L. ivanovii and L. grayi have been reported in certain cases.[icd.codes]
  • monocytogenes, bacteria found in soil and water.[icdlist.com]
  • monocytogenes Septicemia by Listeria monocytogenes Use additional code to identify manifestations, as meningitis (320.7) Comments Probable case definitions are provided as guidelines to assist with case finding and public health management, and are not[canada.ca]
  • monocytogenes 027.0 Excludes congenital listeriosis ( 771.2 ) Applies To Infection by Listeria monocytogenes Septicemia by Listeria monocytogenes Use Additional Use additional code to identify manifestations, as meningitis ( 320.7 ) ICD-9-CM Volume 2[icd9data.com]
  • The causative organism is Listeria monocytogenes. The incidence of Listeria monocytogenes infection in human subjects has been considered sporadic, but recent evidence from Germany indicates a greater frequency (15).[pubs.rsna.org]
Francisella Tularensis
  • Clinical diagnosis is supported by evidence or history of a tick or deerfly bite, exposure to the tissues of a mammalian host of Francisella tularensis, or exposure to potentially contaminated water.[bccdc.ca]
  • Tularensis TULAREMIA : Zoonotic, rabbits Ulceroglandular, oculoglandular, typhoidal, pneumonic Painful suppuration of lymph nodes GRAM(-) ROD: Coccobacillus Facultative Intracellular Parasite Cystine Agar Required -- notify lab 3 days to culture.[kumc.edu]

Treatment

  • Treatment includes prolonged administration of antibiotics, primarily ampicillin and gentamicin, to which the organism is usually susceptible.[icd.codes]
  • Treatment is with antibiotics. Anyone can get the illness. But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems.[icdlist.com]
  • Treatment includes penicillin, ampicillin (often with aminoglycosides), and trimethoprim /sulfamethoxazole.[msdmanuals.com]
  • DNAse Type-B : Diagnostic for non-suppurative sequelae Penicillin-G is treatment of choice.[kumc.edu]
  • Treatment: Penicillin (ampicillin) alone or in combination with gentamicin has been effective. Cephalosporins are not effective. Oculoglandular listeriosis and listerial dermatitis can be treated with erythromycin.[microrao.com]

Prognosis

  • Skin-test available (antigen derived from armadillos) to indicate prognosis Phenolic glycolipid is key antigen CD8-Suppressor cells involved in Lepromatous response.[kumc.edu]

Prevention

  • […] ready-to-eat foods as soon as you can Avoid raw milk and raw milk products Heat ready-to-eat foods and leftovers until they are steaming hot Wash fresh fruits and vegetables Avoid rare meat and refrigerated smoked seafood Centers for Disease Control and Prevention[icdlist.com]
  • […] use precooked and ready-to-eat foods as soon as you can avoid raw milk and raw milk products heat ready-to-eat foods and leftovers until they are steaming hot wash fresh fruits and vegetables avoid rare meat and seafood Centers for Disease Control and Prevention[icd10data.com]
  • Advise high-risk patients to prevent disease by not eating foods most likely to be contaminated. Click here for Patient Education[msdmanuals.com]
  • Chlamydia Trachomatis (Chlamydiaceae) CHLAMYDIA Lymphogranuloma Venereum Leading cause of preventable blindness in the world.[kumc.edu]

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